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Document Title |
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7371408 |
Bone graft substitute composition
A bone graft substitute composition comprising calcium sulfate; a mixing solution selected from the group consisting of sterile water, sodium chloride, phosphate buffered saline, potassium...
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7294187 |
Rapid-hardening calcium phosphate cement compositions
A bone or dental implant material in the form of a paste includes a mixture of calcium phosphate and/or calcium-containing powders and a solution that is (1) an acidic calcium phosphate solution...
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7291179 |
Bone graft substitute composition
Bone graft substitute compositions and methods of making the compositions are disclosed. In some embodiments, a method of making a composition includes contacting a mixing solution with a first...
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7238209 |
Bone replacement material
A bone replacement material for use in a treatment for repairing a vertebral body compression fracture is formed into a pellet having a roughly polyhedral shape. Each pellet having the roughly...
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7189263 |
Biocompatible bone graft material
Biocompatible bone graft material having a biocompatible, resorbable polymer and a biocompatible, resorbable inorganic material exhibiting macro, meso, and microporosities.
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7179299 |
Osteoimplant and method for making same
A method of manufacturing an osteoinductive osteoimplant is provided which comprises the steps of: demineralizing part or all of at least one surface of a monolithic section of cortical bone to a...
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7172629 |
Osteogenic paste compositions and uses thereof
Described are osteogenic paste compositions with enhanced osteoinductive properties for use in bone repair. Compositions comprising a quickly resorbable paste carrier, a more slowly resorbed...
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7163965 |
Process for producing porous composite materials
This invention relates to a process for producing porous and composite materials comprising steps of: freezing a complex containing at least one calcium salt selected from calcium carbonate,...
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7156880 |
Devices and methods for treating defects in the tissue of a living being
An implantable material for deployment in select locations or select tissue for tissue regeneration is disclosed. The implant comprises collagen, ceramics, and or other bio-resorbable materials or...
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7140882 |
Method of producing low molecular weight chitin/chitosan and method of producing an osteoconduction substance
By irradiating 60 Co γ ray to chitin/chitosan, chitin/chitosan having high molecular weight is separated or decomposed into low molecular weight chitin/chitosan. A method of producing an...
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7083672 |
Method and product for phosphosilicate slurry for use in dentistry and related bone cements
The present invention is directed to magnesium phosphate ceramics and their methods of manufacture. The composition of the invention is produced by combining a mixture of a substantially dry powder...
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7063726 |
Plasticized bone grafts and methods of making and using same
The invention provides a plasticized bone and/or soft tissue product that does not require special conditions of storage, for example refrigeration or freezing, exhibits materials properties that...
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7052517 |
Delivery device for biological composites and method of preparation thereof
An apparatus for the delivery of a biological composite and a method, kit, and system for preparing a biological composite is described herein. The biological composite includes both inorganic and...
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7037867 |
Artificial bone graft substitute using calcium phosphate compounds and method of manufacturing the same
A bone graft substitute using magnesium substituted calcium phosphate compounds and a method of manufacturing the same is provided in which the bone graft substitute is used for recovering bones...
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7018460 |
Self-hardening calcium phosphate materials with high resistance to fracture, controlled strength histories and tailored macropore formation rates
A bone replacement material and therapy comprises the combination of calcium phosphate compounds and two or more soluble fillers in the form of fibers, mesh or other materials which have the dual...
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7008450 |
Porous hydroxy apatite containing silicon and magnesium, and a preparation method thereof
Disclosed are a silicon- and magnesium-containing porous hydroxyapatite, and a preparation method thereof which comprises the steps of performing a hydrothermal treatment of a natural coral and...
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7004974 |
Material for bone reconstruction
The invention relates to a preparation for restoring bone in the body of humans or animals in connection with an existing structure, a bone implant or some other prosthetic construction, as well as...
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6989033 |
Implant for recreating verterbrae and tubular bones
The invention relates to an implant for at least partially creating, recreating or stabilizing vertebral bodies or tubular bones. In said implant, a metallic, nonmetallic or ceramic hollow body is...
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6989030 |
Transplant material and method for fabricating the same
A transplant material which is capable of imparting desired mechanical properties, elevating bone tissue repair speed and improving biocompatibility. This transplant material comprises an...
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6977095 |
Process for producing rigid reticulated articles
A process for producing a rigid reticulated article involves coating a reticulated substrate which has open, interconnected porosity with a first dispersion comprising a ceramic or metal powder to...
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6911212 |
Malleable putty and flowable paste with allograft bone having residual calcium for filling bone defects
The invention is directed toward a malleable bone putty and a flowable pastel composition for application to a bone defect site to promote new bone growth at the site which comprises a new bone...
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6902584 |
Bone grafting matrix
A porous three-dimensional bone grafting matrix is provided which is biodegradable. The matrix is preferably formed from mineralized collagen where the mineral comprises particulate calcium...
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6887272 |
Artificial pyramid
Disclosed is an artificial vertebra having a bone-marrow regenerating function, comprising a hydroxyapatite (HAp)/collagen (Col) composite body formed by pressure-dehydrating a coprecipitate of...
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6863694 |
Osteogenic implants derived from bone
An osteogenic osteoimplant in the form of a flexible sheet comprising a coherent mass of bone-derived particles, the osteoimplant having a void volume not greater than about 32% and a method of...
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6846493 |
Synthetic biomaterial compound of calcium phosphate phases particularly adapted for supporting bone cell activity
The present invention is directed to a synthetic biomaterial compound based on stabilized calcium phosphates and more particularly to the molecular, structural and physical characterization of this...
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6840961 |
Machinable preformed calcium phosphate bone substitute material implants
The present invention provides machinable calcium phosphate bone substitute material implants having mechanical properties comparable to those of natural bone. The implants include intimately mixed...
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6764517 |
Tissue repair matrix
A porous three-dimensional tissue repair matrix is provided which is biodegradable. The matrix is preferably formed from mineralized collagen where the mineral comprises particulate calcium...
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6736799 |
Delivery device for biological composites and method of preparation thereof
An apparatus for the delivery of a biological composite and a method, kit, and system for preparing a biological composite is described herein. The biological composite includes both inorganic and...
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6713420 |
Porous ceramics body for in vivo or in vitro use
A porous ceramics body for in vivo or in vitro 1use in which a number of pores are closely distributed in three dimensional directions, adjoining pores thereof being partitioned by wall portions...
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6709463 |
Prosthetic joint component having at least one solid polycrystalline diamond component
Prosthetic joints, components for prosthetic joints, superhard bearing and articulation surfaces, diamond bearing and articulation surfaces, substrate surface topographical features, materials for...
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6692760 |
Polymeric material for artificial bone
A novel polymeric material for artificial bones, comprising a solid or gel-form base containing, as the main component, either a polysaccharide having carboxyl groups or their derivatives, or a...
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6692532 |
Bone repair composite material
There is provided an admixture comprising morsellised bone particles and particles of water-soluble biodegradable glass. The particle size distribution and diameter range is pre-selected to produce...
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6679918 |
Implantable putty material
The present invention provides compositions for an implantable putty material for delivery of active compounds to a patient. More specifically, the present invention provides a material having a pH...
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6616698 |
Bone graft and guided bone regeneration method
An implantable, biocompatible, osteogenic bone graft comprises at least one zone of impermeability to soft tissue ingrowth which is integral with the bone graft. Application of the bone graft to a...
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6602294 |
Implantable substrates for the healing and protection of connecting tissue, preferably cartilage
Implantable substrate for the healing and/or protection of connecting tissue, preferably cartilage, comprising at least one composition for the activation of locally present cells for tissue...
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6591581 |
Method for preparing and inserting round, size specific osteochondral cores in the knee
In a method of performing a hyaline cartilage allograft transplantation procedure in which a surgeon has pre-operatively determined a size of allograft to be needed for the procedure, a service...
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6582715 |
Antimicrobial orthopedic implants
An orthopedic surgical implant of one or more components having a surface which is to be contacted by body tissue and/or fluid. The surface contains an inorganic antimicrobial agent either...
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6569204 |
Bone tissue regenerating composition
A composition for use in bone tissue regeneration and a method for its preparation, for application principally, but not exclusively, in the practice of oral surgery. The composition makes use of a...
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6544289 |
Plasticized bone grafts, and methods of making and using same
The present invention provides a plasticized dehydrated or freeze-dried bone and/or soft tissue product that does not require special conditions of storage, for example refrigeration or freezing,...
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6533820 |
Biomaterials for bone replacements
The present invention involves compositions for use as granular bone replacements. The compositions of the present invention are comprised of hyaluronic acid esters or salts of hyaluronic acid in...
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6530958 |
Tissue regeneration matrices by solid free-form fabrication techniques
Solid free-form (SSF) techniques for making medical devices for implantation and growth of cells from polymers or polymer/inorganic composites using computer aided design are described. Examples of...
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6527810 |
Bone substitutes
A strong, porous article useful as a bone substitute material. The article comprises a continuous strong framework structure having struts defining interstices which interconnect throughout the...
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6511510 |
Osteoinductive ceramic materials
The invention relates to an osteoinductive biomaterial, which is based on a ceramic material and which has a total porosity of 20 to 90%, wherein macropores are present having a size ranging from...
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6506217 |
Moldable post-implantation bone filler and method
Methods for correcting defects at bone repair sites are provided, which use a moldable, post-implantable bone conforming material. The method includes the steps of preparing a bone conforming...
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6437018 |
Malleable paste with high molecular weight buffered carrier for filling bone defects
The invention is directed toward a malleable bone putty and a flowable gel composition for application to a bone defect site to promote new bone growth at the site which comprises a new bone growth...
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6436138 |
Process for producing flexible sheets from demineralized, elongate, bone particles
A process for fabricating shaped material from demineralized bone particles includes the steps of applying a liquid slurry of demineralized bone particles to a support, removing excess liquid form...
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6364912 |
Pleiotrophin-based compositions for enhancing connective tissue repair
Bioactive compositions that induce or enhance the repair of damaged or diseased connective tissues upon contact of the tissues with the compositions in vivo include an effective amount of...
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6340648 |
Calcium phosphate porous sintered body and production thereof
A calcium phosphate porous sintered body which comprises spherical pores communicating with one another substantially throughout the body with a porosity of 55% or more and 90% or less, and has an...
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6322592 |
Macro-porous composite support for medicinal substance(s) that can be used as a bone reconstitution material and a method of producing it
The invention relates to a macro-porous composite that can be used as a bone reconstitution material. The composite is made up of a combination of synthetic aragonite and at least one medicinal...
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6309422 |
Bone grafting material
The application relates to a synthetic bone grafting powder mix comprising a calcium compound and protein. Preferably, the ratio by weight of the calcium compound to protein is between 90:10 to...
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