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7377943 |
Surface treated metallic implant and blasting material
The invention relates to a metallic implant, which has vitreous-crystalline bioactive material on the surface thereof. According to the invention, a metallic implant base body arranged on the...
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7361724 |
Self assembling monolayer compositions
A surface coating composition for providing a self-assembling monolayer, in stable form, on a material surface or at a suitable interface, as well as a method of preparing such a composition and a...
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7247364 |
Coating for implantable medical devices
An implantable medical device, such as a stent, is disclosed having a coating. The coating includes a poly(butylene terephthalate-co-ethylene glycol)polymer. The coating can also include a drug.
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7192445 |
Medical prosthetic devices and implants having improved biocompatibility
Disclosed are medical prosthetic devices or medical implants which exhibit improved biocompatitibly. The devices or implants include a metal material, e.g. titanium, in which the metal surface...
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7163920 |
Peptide with osteogenic activity
The present invention provides a composition including an isolated or recombinant peptide component that has osteogenic cell proliferative activity. The peptide, which promotes proliferation of...
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7087086 |
Biological agent-containing ceramic coating and method
The invention provides an implantable article, a method of preparing the same, and methods of modifying a ceramic-coated implantable article. The implantable article comprises a biocompatible...
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7063884 |
Stent coating
A stent comprising a coating layer is disclosed. The coating layer has a hydrophobic component and a hydrophilic component, wherein a region of the coating layer on or about the outermost surface...
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7018411 |
Endoprothesis with galvanised silver layer
A bone replacement endoprosthesis has a metallic support structure, at least part of the surface of which is galvanically silvered. Beneath the silver layer a bond layer is provided which can...
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7015206 |
Use of a polysaccharide excreted by the Vibrio diabolicus species in bone repair
The invention concerns the use of a polysaccharide excreted by the Vibrio diabolicus species for making a medicine with cicatrising activity, in particular bone repair activity. The invention...
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7014661 |
Transcutaneous prosthesis
A transcutaneous prosthesis is disclosed comprising a first component ( 1 ) shaped for implantation into a bone ( 2 ), a second component ( 4 ) intended for location between the bone ( 2 ) and the...
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7004975 |
Coated joint endoprosthesis
Joint endoprostheses are provides which respectively have a joint part with a metallic core, wherein the metallic core is coated, in regions that roll and/or slide on another joint part during...
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6969400 |
Synthetic implant with nonimmunogenicity coating
Provided are crosslinked polymer compositions that include a first synthetic polymer containing multiple nucleophilic groups covalently bound to a second synthetic polymer containing multiple...
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6926919 |
Method for fabricating a coating for a medical device
Methods for fabricating coatings for implantable medical devices are disclosed. The coatings include blends of hydrophilic and hydrophobic polymers. The methods provide for treatment of the...
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6863693 |
Phospholipid-coated implants
A prosthesis or implant has a surface carrying a coating comprising at least one phospholipid at a concentration to improve osteointegration. A method of making such a prosthesis or implant and a...
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6749639 |
Coated prosthetic implant
A prosthesis for implanting into a bone having a cavity is disclosed. The prosthesis comprises a body and a stem. A first coating including a bone ingrowth promoting material that promotes ingrowth...
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6736849 |
Surface-mineralized spinal implants
A spinal implant is provided to integrate with and support vertebrae in a vertebral column. The spinal implant includes a body and a mineralized, bioactive surface coating chemically bonded to a...
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6730129 |
Implant for application in bone, method for producing such an implant, and use of such an implant
An implant for application in bone, especially jaw bone, is provided. The implant includes a unit that can be applied in the bone, and which is made of a biocompatible material such as titanium....
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6726718 |
Medical articles prepared for cell adhesion
A prosthesis is formed from a biocompatible material having one or more associated cell adhesion stimulating proteins. The biocompatible material can be a ceramic material or a carbon coated...
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6719989 |
Sustained release drug carrier, and method of manufacturing sustained release drug carrier
A sustained release drug carrier comprises a ceramic composite which is formed by bonding a plurality of ceramic bodies together, and drugs impregnated into the ceramic composite. A method of...
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6627321 |
Implants with modified surfaces for increased biocompatibility, and method for production thereof
An implant with a surface modified for improved bio-compatiability consisting of a metal or an alloy thereof, said implant surface comprising a modified outer layer is disclosed, wherein said metal...
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6582715 |
Antimicrobial orthopedic implants
An orthopedic surgical implant of one or more components having a surface which is to be contacted by body tissue and/or fluid. The surface contains an inorganic antimicrobial agent either...
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6569547 |
Hard tissue repairing materials and the process for producing the same
A hard tissue repairing material including a base material and a surface layer having a crystalline zirconia covering the base material, being characterized in that the film includes a Zr—OH...
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6530958 |
Tissue regeneration matrices by solid free-form fabrication techniques
Solid free-form (SSF) techniques for making medical devices for implantation and growth of cells from polymers or polymer/inorganic composites using computer aided design are described. Examples of...
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6508838 |
Compositions for medical implantation
A composition or device suitable for orthopedic or dental implantation to bone, characterized by tartrate-resistant acid phosphatase (TRAP) adsorbed to a porous hydroxyapatite substratum.
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6497729 |
Implant coating for control of tissue/implant interactions
A tissue/implant interface, comprising an implant and a bioactive polymer layer adjacent at least a portion of the outer surface of the implant, wherein the polymer layer contains at least one...
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6419708 |
Calcium-phosphate coated implant element
The invention relates to an implant element for permanent anchorage in bone tissue in which at least the surface intended to face the tissue in the implantation region is made of a biocompatible...
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6371985 |
Prostheses restrained by immediate attachment while ingrowth proceeds naturally over time
The invention is a surgically implantable bone and bone joint prosthesis which is designed to be directly attached during surgery and which includes ingrowth receptive zones or stationing sites for...
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6361567 |
Non-irritating antimicrobial coating for medical implants and a process for preparing same
The present invention provides a process of forming an antimicrobial coating on a surface of a medical implant, the coating comprising an antimicrobially effective amount of antimicrobial metal...
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6344061 |
Device for incorporation and release of biologically active agents
The invention provides an implantable device coated with a layer of calcium phosphate and optionally one or more biologically active substances such as growth factors, lipis, (lipo)polysaccharides,...
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6251142 |
Implantation device and a kit including the device
The apparatus comprises an implantation device having a body, the surface of which has at least a portion coated with a receptor, and a preparation containing a ligand formed from the combination...
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6235061 |
Poly(organophosphazene) matrices for bone replacement
A highly porous three-dimensional biodegradable poly(organophosphazene) matrix with hydrolytically unstable side chains is prepared and used as a scaffold for the growth of osteoblast cells. In a...
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6221111 |
Bioactive surface layer for bone implants
A bioactive surface layer with 0.01 μm to 5 mm thickness is suitable for a metallic bone implant. The surface layer has the following composition: (A) calcium compounds (CaX) consisting of...
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6143036 |
Bone augmentation for prosthetic implants and the like
Bone augmentation in a mammalian body by insertion of a mesh comprising one or more fibrillar wires having a coating into a bone cavity or socket. The one or more fibrillar wires are arranged or...
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6017366 |
Resorbable interposition arthroplasty implant
A resorbable implant for interposition arthroplasty which is intended to fill a void between two adjacent bone ends, providing a cushion between the bone ends to prevent impingement of the bone...
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5980973 |
Implantable medical device with biocompatible surface and method for its manufacture
A method of providing biocompatible surface texturing on a metal component of an implantable device and the device so produced. The coating is provided by applying particles of metal falling...
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5035718 |
Joint prosthesis
A joint prosthesis, especially for a hip joint has a metal shaft receivable in the marrow cavity of the bone, a closure plate at the upper end of the shaft, and a formation adapted to form the ball...
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4904264 |
Artifical joint system
The invention relates to an artificial joint system which, by a combination of defined pretension in the implant in the resection plane and a wholly or partially resorbable shaft or clamping system...
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4705694 |
Process for making bioactive coatings on osseous prostheses, and prostheses thus obtained
The present invention relates to a process for making bioactive coatings on osseous prostheses, wherein a mist of particles containing calcium ions and orthophosphate ions is made from solutions...
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4702930 |
Method of producing implantable bone replacement materials
Metallic implants with a coating of hydroxyl apatite are described. Hot isostatic pressing permits pore-free compaction of the hydroxyl apatite layer and results in firm bonding of the layer on the...
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4636218 |
Artificial articulation
An artificial articulation includes a socket which has a spherical inner surface, a bone head ball member which is pivotably, slidably received in the spherical inner surface of the socket, and a...
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4542539 |
Surgical implant having a graded porous coating
This biologically compatible surgical prosthetic implant has a multi-layer coating formed from metallic particles having sizes which increase in the direction from the metallic body of the implant...
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4234972 |
Bioglass coated metal substrate
A prosthesis for cement-free bonding to bone comprising a metal substrate coated with a biologically active glass or glass-ceramic of uniform composition and thermal coefficient of expansion and...
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4202055 |
Anchorage for highly stressed endoprostheses
An implantable prosthesis anchorage which contains a non-porous outer coating in the regions which is positioned in contact with bone. The non-porous outer coating consists of (i) at least one...
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3924274 |
An adjunct and method for facilitating implantation of joint prostheses
Implantation of joint prostheses by means of mineral cement adhesives is facilitated by using a temporary barrier shield of biologically compatible material between the cement and the bone tissue...
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3919723 |
Bone shaft or bone joint prosthesis and process
A bone shaft or bone joint prosthesis made of a compacted Al 2 O 3 ceramic, cement-free implant. At least one substance capable of releasing bone-growth stimulating ionic material (i.e., lithium...
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