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7594974 |
Method of cutting material for use in implantable medical device
A method of cutting material for use in an implantable medical device employs a plotted laser cutting system. The laser cutting system is computer controlled and includes a laser combined with a...
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7591847 |
Stentless bioprosthetic valve having chordae for replacing a mitral valve
A stentless bioprosthetic valve includes at least one piece of biocompatible material comprising a bi-leaflet conduit having a proximal end and a distal end. The proximal end defines a first...
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7563280 |
Efficient implantation of heart valve prostheses
Tools can be used to assist with the implantation of heart valve prostheses, especially stentless aortic heart valve prostheses. In some embodiments, a heart valve prosthesis includes a plurality...
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7556645 |
Translumenally implantable heart valve with formed in place support
A cardiovascular prosthetic valve includes a cuff having a distal end and a proximal end. An inflatable structure is coupled to the cuff and has at least one inflatable channel that forms a...
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7547322 |
Prosthetic valve and method for making same
A prosthetic valve for placement within a body passage includes at least two valve leaflets made from a first layer of either peritoneal fascia tissue or pleural tissue. Support structure is...
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RE40570 |
Apparatuses and methods for treating biological tissue to mitigate calcification
An apparatus for treating fixed biological tissue to inhibit calcification of the biological tissue following implantation thereof in a mammalian body. The apparatus includes a container for...
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7323010 |
Biomaterial including animal corneal tissue
Biomaterial including tissues basically obtained from an animal cornea, in particular, from a fish cornea. A cardiac valve ( 10 ) which may envisage at least one cusp ( 15 ) made with an organic...
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7316712 |
Tissue heart valve with annulus support structure
A heart valve prosthesis can be formed with a harvested tissue heart valve and a sewing rim that extends outwardly from the annulus of the harvested heart valve for easier attachment of the...
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7141064 |
Compressed tissue for heart valve leaflets
A process and system for compressing bioprosthetic tissue for use in medical implants. The process involves placing the tissue between two compressive surfaces and applying a force to reduce any...
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7037333 |
Prosthetic heart valve
A tubular prosthetic semilunar or atrioventricular heart valve is formed by cutting flat, flexible leaflets according to a pattern. The valve is constructed by aligning the side edges of adjacent...
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7029434 |
Methods for treating implantable biological tissues to mitigate post—implantation calcification
A method for treating fixed biological tissue inhibits calcification of the biological tissue following implantation thereof in a mammalian body. The method includes placing the biological tissue...
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7025780 |
Valvular prosthesis
A valvular prosthesis and method of using the prosthesis are disclosed. A valve apparatus is located within a stent apparatus, such that the prosthesis is deformable between a first condition and a...
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7014655 |
Method for conserving biological prostheses, conserved biological prostheses and conserving solutions
The invention concerns a method of conserving biological prostheses, wherein the method includes the following steps: (a) treating biological prostheses with a solution which contains a mixture of...
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6945996 |
Replacement mitral valve
A sewing ring ( 12 ) has a diameter commensurate with a diameter of a removed mitral valve. Skirts ( 44, 46 ) of mesh or net material extend downward from the sewing ring and line the walls of an...
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6911043 |
Prosthetic heart value
A tubular prosthetic semilunar or atrioventricular heart valve is formed by cutting flat, flexible leaflets according to a pattern. The valve is constructed by aligning the side edges of adjacent...
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6872226 |
Method of cutting material for use in implantable medical device
A method of cutting material for use in an implantable medical device employs a plotted laser cutting system. The laser cutting system is computer controlled and includes a laser combined with a...
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6861211 |
Stabilization of implantable bioprosthetic devices
The invention relates to methods of stabilizing glycosaminoglycans in a biological tissue (e.g. a bioprosthetic implant) in conjunction with cross-linking of protein in the tissue. The methods of...
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6837902 |
Methods of making bioprosthetic heart valves with strain matched leaflets
Heart valve leaflet selection methods and apparatuses which subject individual leaflets to loads and measure the resulting deflection to more reliably group leaflets of similar physical...
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6830586 |
Stentless atrioventricular heart valve fabricated from a singular flat membrane
A stentless atrioventricular valve intended for attaching to a circumferential valve ring and papillary muscles of a patient comprising a singular flexible membrane of tissue or synthetic...
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6719789 |
Replacement heart valve
A prosthetic heart valve has leaflets made of a thin and flexible material. The side edges of adjacent leaflets are sewn together so as to form a substantially tubular valve structure having an...
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6652583 |
Cardiac valve replacement
The invention provides a replacement heart valve which contains an acellular matrix as a structural scaffold. The scaffold is seeded with isolated myofibroblasts and/or endothelial cells prior to...
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6610088 |
Biologically covered heart valve prosthesis
A system and method are disclosed for covering a heart valve prosthesis with biological tissue, such as pericardium. In one aspect, the prosthesis includes a stent that is covered with a fabric...
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6592618 |
In vitro modification of cardiac valvular xenografts
The present invention is directed to methods for obtaining heart valves from a donor animal that have a reduced tendency to cause inflammation when implanted into a human patient. The valves...
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6558417 |
Single suture biological tissue aortic stentless valve
A semilunar stentless valve is formed entirely of biological tissue, and has a plurality of leaflets that are joined to form an annulus and coapt to form a one-way valve. The leaflets open fully to...
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6553681 |
Methods for measuring a bio-material for use in an implant
A system and method to facilitate thickness measurement of bio-material workpiece, preferably a sheet, and to topographically map the sheet into similar thickness zones for later use. In...
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6540781 |
Cryopreserved homografts and other stentless bioprosthetic heart valves having natural tissue sewing rings
Pre-trimmed, cryopreserved homografts and other stentless bioprosthetic heart valves having natural tissue sewing rings formed thereon. The sewing ring may be formed of strip of pericardium or...
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6497725 |
Differential treatment of prosthetic devices
An apparatus is disclosed for differentially treating a medical device. One portion of the device is treated with a first fluid and a separate portion is treated with a second fluid. The second...
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6413275 |
Apparatus for testing bioprosthetic heart valve leaflets
Heart valve leaflet selection methods and apparatuses which subject individual leaflets to loads and measure the resulting deflection to more reliably group leaflets of similar physical...
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6409759 |
Harvested tissue heart valve with sewing rim
A heart valve prosthesis can be formed with a harvested tissue heart valve and a sewing rim that extends outwardly from the annulus of the harvested heart valve for easier attachment of the...
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6375680 |
Substrates for forming synthetic tissues
A prosthesis is formed from a substrate with an associated attraction compound. The attraction compound binds viable precursor cells to the substrate. Thus, the substrate forms a synthetic tissue...
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6358277 |
Atrio-ventricular valvular device
An anatomically designed atrioventricular valve is made of biologically compatible synthetic membrane or biological membrane of autologous, homologous or heterologous origin. A single piece of the...
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6350282 |
Stented bioprosthetic heart valve
A supported bioprosthetic heart valve is provided. The valve includes a stent and a bilogical valve member. The stent has an annular frame defined by a support rail. The support rail is formed to...
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6338740 |
Flexible heart valve leaflets
A heart valve with a structural stent and radially moveable cusps and commissures. The stent may be of three separate elements, each having a cusp portion and two commissure portions. The...
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6328763 |
Optimized geometry of a tissue pattern for semilunar heart valve reconstruction
A new and unique, optimized, two-dimensional heart valve tissue pattern, valve, and a method of reconstructing a three-dimensional semilunar heart valve, or portion thereof. In one preferred...
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6270526 |
Replacement semilunar heart valves using flexible tubes
A method is disclosed for using tubular material to replace a semilunar heart valve (i.e., an aortic or pulmonary valve). To create such a replacement valve, the native valve cusps are removed from...
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6254635 |
Calcification-resistant medical articles
Medical articles can include biocompatible material with a deposit of anticalcific elemental metal. The biocompatible material can be tissue, fabric or the like. The biocompatible material can be...
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6245105 |
Method of testing bioprosthetic heart valve leaflets
Heart valve leaflet selection methods and apparatuses which subject individual leaflets to loads and measure the resulting deflection to more reliably group leaflets of similar physical...
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6165216 |
Human cardiac valve placement with marine mammal ventricular outflow (aortic or pulmonary) valve
The present invention provides a method of treating human cardiac valve dysfunction, by replacing the existing valve with a novel bioprosthesis of the present invention which comprises a marine...
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6126686 |
Artificial vascular valves
A method for preparing vascular valves from submucosal tissue is described. Both bicuspid and tricuspid valve constructs are described. The bicuspid constructs can be formed with or without a...
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6110201 |
Bifurcated biological pulmonary valved conduit
The present invention comprises a pulmonary valved conduit that permits inflow diameters greater than about 22 mm while still maintaining the advantages of a naturally-formed biological valved...
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6060640 |
Multiple-layer, formed-in-place immunoisolation membrane structures for implantation of cells in host tissue
A permeable structure forms a chamber to hold living cells. The structure includes a first permeable region surrounding at least a portion of the chamber having a conformation that, when implanted...
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5935168 |
Glutaraldehyde-fixed bioprostheses
Methods for treating glutaraldehyde-fixed collagenous tissues to mitigate there propensity for subsequent calcification and to improve durability. Collagenous tissues which have been harvested and...
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5549666 |
Natural tissue valve prostheses having variably complaint leaflets
Variably compliant natural tissue valve leaflets and vascular bioprosthetics incorporating variably compliant leaflets are provided along with methods for their manufacture. The variably compliant...
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5489297 |
Bioprosthetic heart valve with absorbable stent
The invention relates to a bioprosthetic heart valve having leaflets affixed to a substantially absorpable stent. The leaflets can be derived from a biological membrane which is affixed to the...
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5336258 |
Stentless heart valve and holder
A stentless aortic heart valve having a disposable holder with a removable handle can be manually reversed by the physician during suturing to provide a relatively unobstructed view into the...
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5080670 |
Bioprosthetic valve
A bioprosthetic valve made from a biological tissue containing collagen which has been cross-linked with a polyepoxy compound is disclosed. The valve has excellent biocompatibility and is durable...
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4790844 |
Replacement of cardiac valves in heart surgery
A cardiac valve has an annular body of unsupported natural or artificial tissue. The annular body has a bishop's miter shape with a cylindrical end and a pair of diametrically-opposite triangular...
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4778461 |
Heart valve prosthesis and process for its production
A heart valve prosthesis for replacing the aortic valve or the pulmonary valve, consisting of a support ring with at least two commissure supports in each case and flexible cusps, is characterized...
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4759758 |
Prosthetic heart valve
An improved prosthetic heart valve comprises a support body or stent covered by a layer of biological tissue having only the smooth surfaces thereof presented outwardly. The stent has a cutaway...
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4666442 |
Cardiac valve prosthesis with valve flaps of biological tissue
A cardiac valve prosthesis comprises an annular frame and a valve sleeve with a plurality of valve flaps which are forced apart by the blood passing through the prosthesis in one direction and...
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