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9017405 Skin substitute and wound dressing with variable pore sizes  
An improved skin substitute is presented comprised of a silicone layer backed up with a woven nylon fabric layer, the silicone layer possessing a regular pattern of slits that permit the porosity...
8992613 Unshrunken tissue equivalent and methods for producing such an unshrunken tissue equivalent  
The invention relates to a method for producing an unshrunken tissue equivalent. Said method is comprising in that: a mixture is produced that contains at least one element of an extracellular...
8790636 Human skin equivalents expressing exogenous polypeptides  
The present invention relates generally to compositions for wound closure. More specifically, the present invention provides human skin equivalents engineered to express exogenous polypeptides...
8747467 Muscle-based grafts/implants  
The present invention is directed to a composition comprising a matrix suitable for implantation in humans, comprising defatted, shredded, allogeneic human muscle tissue that has been combined...
8728170 Bioerodible nano-fibrous and nano-porous conductive composites  
A bioerodible conductive tissue scaffold that can provide, e.g., improved tissue growth.
8728466 Treating burn injuries with reduced hypertrophic scarring  
This document provides methods and materials involved in treating burn injuries. For example, methods and materials for using skin grafts (e.g., autologous skin grafts) treated with an autologous...
8709081 Cellular scaffold  
A cellular scaffold that is suitable for tissue regeneration, cell culture and in vitro assays. The invention relates to a layered cell scaffold that is seeded with mesenchymal and ectodermal...
8394141 Connective-tissue-based or dermal-tissue-based grafts/implants  
The present invention is directed to a composition comprising a matrix suitable for implantation in humans, comprising defatted, shredded, allogeneic human muscle tissue that has been combined...
8337554 Skin substitute membrane, mold, and method of evaluating external preparation for skin  
A skin substitute membrane includes a surface on one side including a groove-shaped depressed portion and a planar portion, the depressed portion having a cross section having a chamfered V-letter...
8292956 Silicone elastomer composition for artificial integument  
The present invention relates to a silicone elastomer composition for an artificial integument which satisfies the following formula: tan δ≧0.23−0.006X wherein tan δ represents the loss tangent of...
8257435 Skin integrated device  
A skin integrated device for implantation with an improved device-skin interface for the ingrowths of skin cells and tissues throughout the pores, having a solid frame, which may also be...
8105380 Cellular scaffold  
A cellular scaffold that is suitable for tissue regeneration, cell culture and in vitro assays. The invention relates to a layered cell scaffold that is seeded with mesenchymal and ectodermal...
8092531 Human skin equivalents expressing exogenous polypeptides  
The present invention relates generally to compositions for wound closure. More specifically, the present invention provides human skin equivalents engineered to express exogenous polypeptides...
8049059 Medical graft device with meshed structure  
A tissue graft product includes at least one collagen layer comprised of submucosa or renal capsule tissue having slits therein to provide a mesh pattern which in turn establishes a graft...
7955790 Skin substitutes with improved barrier function  
The present invention relates to in vitro cultured skin substitutes, and in particular to in vitro cultured skin substitutes that have improved barrier function. In some embodiments, improved...
7815931 Artificial skin substitute  
An improved skin substitute is presented comprised of non-biological materials produced with a series of regularly-spaced pores and a nylon weave netting. The top component is a thin...
7763081 Tissue graft  
The present invention relates to a method of preparing a tissue graft material. The invention also relates to a multipurpose tissue graft material and to methods of using same as a replacement for...
7736894 Method for constructing reconstructed skin  
The present invention relates to a method for constructing human skin tissue, in which human skin tissue is reconstructed on a body surface of an immunodeficient non-human animal.
7674291 Human skin equivalents expressing exogenous polypeptides  
The present invention relates generally to compositions for wound closure. More specifically, the present invention provides human skin equivalents engineered to express exogenous polypeptides...
7244552 Artificial dermis and production method therefor  
Artificial dermis (1) obtained from plasma with platelets (2) and human fibroblasts. The plasma with platelets (2) is obtained from the fractionating of total blood (4) from the patient (8) by...
7160326 Method and apparatus for implantation of soft tissue implant  
A method of securing a soft tissue implant to damaged tissue of a patient is provided. The method includes preparing a layer of extracellular matrices (ECM) for surgery. The method further...
7004969 Artificial skin and method for evaluating UV screening agent by use of the same  
Artificial skin having a thickness of 100 to 1,000 μm, and prepared from a polymer which, when formed into a thin film having a thickness of 100–1,000 μm, exhibits a percent transmission of light...
6964869 Method and composition for skin grafts  
A chimeric skin comprising immortalized human keratinocyte cells cocultured with donor keratinocytes is disclosed.
6861211 Stabilization of implantable bioprosthetic devices  
The invention relates to methods of stabilizing glycosaminoglycans in a biological tissue (e.g. a bioprosthetic implant) in conjunction with cross-linking of protein in the tissue. The methods of...
6790454 Processes for the preparation of novel collagen-based supports for tissue engineering, and biomaterials obtained  
A composite product is disclosed as a collagen support comprising at least one porous collagen layer covered on at least one side with an essentially compact collagen membrane consisting either of...
6733530 Material and method for engraftment of a composite biocompatible skin graft on the neodermis of artificial skin  
Autologous cultured keratinocytes are grown on a biosynthetic and biocompatible substratum following pre-seeding with autologous or allogenic dermal fibroblasts. The resultant composite material...
6712850 Porous tissue scaffolds for the repair and regeneration of dermal tissue  
The present invention is a synthetic, biocompatible, bioabsorbable, porous foam tissue scaffolds possessing physicochemical properties suitable for use in the repair and regeneration of dermal...
6699287 Dermal scaffold using alkaline pre-treated chitosan matrix or alkaline pre-treated chitosan and alkaline pre-treated collagen mixed matrix  
Disclosed are a dermal scaffold comprising alkaline pre-treated free amine-containing chitosan matrix, alkaline pre-treated free amine-containing chitosan and alkaline pre-treated collagen mixed...
6652594 Resorbable implant materials  
A non-crosslinked, decellularized and purified mammalian tissue (e.g., bovine pericardium) having particular use as an implantable resorbable material. The material is treated by alkylating its...
6541023 Use of collagen of aquatic origin for the production of supports for tissue engineering, and supports and biomaterials obtained  
Use of collagen of aquatic origin for the production of supports for tissue engineering is disclosed. The collagen may be obtained from fish skin, preferably in its native form. Novel tissue...
6537313 Surgical prostheses  
A biomaterial is provided which is suitable for use in surgery in a human patient. It includes a coherent layer of non-human collagenous tissue which has been subjected to glutaraldehyde tanning...
6383220 Artificial skin  
The invention relates to an artificial skin based on a copolymer of a polyalkylene glycol and an aromatic polyester, which skin has a thickness between 50 and 2000 μm, and which skin has an upper...
6364908 Method and instruments for stretching skin grafts  
A method for spreading skin grafts, wherein the skin grafts are placed on an elastic membrane, after which the membrane is stretched in at least two directions substantially perpendicular to each...
6341952 Fabrication of tissue products with additives by casting or molding using a mold formed by solid free-form methods  
A system for molding a tissue or substitute tissue product in a mold having an exterior surface, and an interior surface, wherein at least one portion of the interior surface is porous and whose...
6162962 Areal implant  
An areal implant, in particular for abdominal wall closure, has a flexible basic structure made from a knitted fabric comprising non-resorbable or slowly resorbable material or a combination of...
6133236 Products and methods for improving keratinocyte adhesion to the dermis  
Improving adhesion of epidermis to an underlying dermal substrate including the step of providing an amount of purified kalinin between the epidermis and dermal substrate wherein the kalinin...
6110212 Elastin and elastin-based materials  
It is a general object of the invention to provide a method of effecting repair or replacement or supporting a section of a body tissue. Specifically to provide an elastin or elastin-based...
6110208 Artificial skin containing as support biocompatible materials based on hyaluronic acid derivatives  
Artificial human skin is disclosed which is based on: (a) a microperforated membrane based on a hyaluronic acid derivative on which keratinocytes have been seeded and cultured; (b) an underlying...
6039760 Composite living skin equivalent  
Skin equivalents and processes for preparing them are described. The living skin equivalent comprises a layer of cultured keratinocyte cells, a layer of high purity, non-porous collagen and a...
5968097 Elastic device for extending living tissue and having large capacity for elongation  
A device for extending living tissue includes at least two rigid supports that respectively have a plurality of hook-like barbs on one end thereof for attachment to the skin, each point of...
5945101 Skin model system  
This invention relates to a skin model system that can be used as an in vitro test system or which can be used for therapeutic purposes. The skin model system comprises a three-dimensional,...
5849579 Native-state histoculturing method for skin  
Methods and compositions for a native-state histoculturing system for skin are disclosed. Skin samples are placed on an extracellular support matrix immersed in a medium whereby the internal...
5830507 Biotherapeutic cell-coated microspheres  
A living skin replacement for the treatment of partial-thickness and full-thickness skin injuries, such as burns and other wounds, consists of a slurry of cell-coated microspheres which can be...
5723009 Device for extending living tissue  
A method for extending skin tissue involving an apparatus that it surgically implanted within the human body, and in particular, beneath the scalp area to extend hair producing tissue for reducing...
5716411 Method of skin regeneration using a collagen-glycosaminoglycan matrix and cultured epithelial autograft  
The present invention relates to a method of skin regeneration of a wound or burn in an animal or human. This method comprises the steps of initially covering the wound with a collagen...
5697383 Preparation of inexpensive, HIV-free human skin allograft  
A new method for the preparation and sterilization of skin allografts is presented. Human skin allografts are radiated in the present invention and applied as a temporary wound dressing on a graft...
5667961 Skin substitute  
The invention concerns a skin substitute composed of a dermis equivalent covered with an epidermis equivalent. The dermis equivalent is a film formed from a type I collagen gel containing...
5662714 Device for extending living tissues  
The technical field of the invention is that of making surgical materials implantable in the human body. The extender device (2) comprises at least two independent resilient members (8) each...
5658331 Biocompatible perforated membranes, processes for their preparation, their use as a support in the in vitro growth of epithelial cells, the artificial skin obtained in this manner, and its use in skin grafts  
The invention relates to biocompatible membranes constructed of materials of natural, synthetic or semisynthetic origin, and having a thickness of between 10 and 500μ, characterized by containing...
5634944 Body membrane prosthesis  
A prosthesis and method are disclosed for patching openings in body membranes such as the dura mater. The novel prosthesis includes patch comprising a patch flange and a suture flange extending...

Matches 1 - 50 out of 69 1 2 >