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8182527 |
Heparin barrier coating for controlled drug release
Medical devices, and in particular implantable medical devices, may be coated to minimize or substantially eliminate a biological organism's reaction to the introduction of the medical device to...
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8105391 |
Merhods of treatment with devices having a coating containing pegylated hyaluronic acid and a pegylated non-hyaluronic acid polymer
Provided herein are a method, which comprises implanting in a patient an implantable device comprising a coating that includes a PEGylated hyaluronic acid and a PEGylated non-hyaluronic acid...
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8061298 |
Stent mandrel fixture and method for selectively coating surfaces of a stent
A stent mandrel fixture for supporting a stent during the application of a coating substance is provided. A method supporting a stent during the application of a coating substance is also provided.
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8051798 |
Mounting assembly for a stent and a method of using the same to coat a stent
A mounting assembly for a stent and a method of coating a stent using the assembly are provided.
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7918181 |
Stent mandrel fixture and method for reducing coating defects
A stent mandrel fixture for supporting a stent during the application of a coating substance is provided.
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7887572 |
Implantable devices for accelerated healing
Implantable devices (e.g., stent) having a protein patterning or bioactive patterning for accelerated healing and method of forming and using the same are provided.
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7887576 |
Endoluminal device with extracellular matrix material and methods
An endoluminal device comprises a stent and a tubular graft supported by the stent. The graft has a proximal and a distal opening and comprises a synthetic material and a bioremodelable material....
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7749263 |
Poly(ester amide) filler blends for modulation of coating properties
Provided herein is a PEA polymer blend and coatings or implantable devices formed therefrom.
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7735449 |
Stent fixture having rounded support structures and method for use thereof
A stent fixture for supporting a stent during the application of a coating substance is provided.
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7628859 |
Mounting assembly for a stent and a method of using the same to coat a stent
A mounting assembly for a stent and a method of coating a stent using the assembly are provided.
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7604700 |
Stent mandrel fixture and method for selectively coating surfaces of a stent
A stent mandrel fixture for supporting a stent during the application of a coating substance is provided. A method supporting a stent during the application of a coating substance is also provided.
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7591841 |
Implantable devices for accelerated healing
Implantable devices (e.g., stent) having a protein patterning or bioactive patterning for accelerated healing and method of forming and using the same are provided.
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7585319 |
Self-aggregating protein compositions and use as sealants
An implantable member for use in the body is provided herein. This implantable member includes a porous biocompatible substrate; the substrate having at least one surface sealed fluid-tight with...
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7563278 |
Drug-eluting intravascular prostheses and methods of use
The present invention provides intravascular prostheses and methods of production and use. An implantable device for treating a vascular disease or disorder includes an intravascular prosthesis...
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7556837 |
Method for coating stents
An apparatus for coating implantable medical devices, such as stents, and a method of coating stents using the apparatus is also disclosed. The apparatus includes a barrier or barriers for...
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7550004 |
Endoluminal device with extracellular matrix material and methods
An endoluminal device comprises a stent and a tubular graft supported by the stent. The graft has a proximal and a distal opening and comprises a synthetic material and a bioremodelable material....
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7301001 |
Bioabsorbable, biobeneficial polyester polymers for stent coatings
This disclosure covers polymers, some of which are useful in medical device applications. Some of these medical devices are implantable within a mammalian body, such as in a body lumen. The...
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7220276 |
Endovascular graft coatings
An endovascular graft, having both an expandable stent portion and a stent cover portion positioned, the graft itself and/or a stent cover-portion coated with a bioactive agent adapted to promote...
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7175658 |
Artificial vascular grafts, their construction and use
The present invention relates to artificial vascular grafts, methods for manufacturing and uses for them. The grafts are coated on their lumen with UP50. The grafts comprise an inner surface on...
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7094256 |
Coatings for implantable medical device containing polycationic peptides
Coatings for implantable medical devices and methods for fabricating the same are disclosed. The coatings include carboxylated acrylates and polycationic peptides, for example R7.
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7070607 |
Bioabsorbable polymeric implants and a method of using the same to create occlusions
A new embolic agent, bioabsorbable polymeric material (BPM) is incorporated to a Guglielmi detachable coil (GDC) to improve long-term anatomic results in the endovascular treatment of intracranial...
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7037332 |
Medical device with coating that promotes endothelial cell adherence
A medical device coated with one or more antibodies and one or more layers of a matrix is disclosed. The antibodies or fragments thereof react with an endothelial cell surface antigen. Also...
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6972054 |
Coupling device for a stent support fixture
A coupling device to connect a stent support fixture to a processing apparatus is provided.
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6955723 |
Mandrel for supporting a stent and method of using the mandrel to coat a stent
A device for supporting a stent is disclosed. The device includes a mandrel and a gear. The gear allows for rotation of the stent during a coating process.
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6638520 |
Structures and methods for promoting vascularization
One aspect of the present invention provides implantable medical devices that comprise: (a) a device body; and (b) a surface layer attached to at least a portion of the device body, the surface...
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6605115 |
Method and composition for inhibiting cardiovascular cell proliferation
Cardiovascular cell proliferation in a blood vessel subjected to trauma, such as angioplasty, vascular graft, anastomosis, or organ transplant, can be inhibited by contacting the vessel with a...
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6579322 |
Biomedical material for improving the adhesion and proliferation of cells and a modified artificial vessel
A novel biomedical material, which is characterized by coating a genetically engineered CBD-RGD peptide layer on the surface of a biomedical material consisting of PU to improve the attachment of...
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6527863 |
Support device for a stent and a method of using the same to coat a stent
A support device for a stent and a method of coating a stent using the device are provided.
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6193749 |
Calcification-resistant biomaterials
In general, the invention features a bioprosthetic article including a biocompatible material having at least one bound exogenous storage structure, the storage structure having a quantity of...
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6187039 |
Tubular submucosal graft constructs
An easy-to-produce and mechanically strong tube of an implantable submucosal tissue has been developed which is manufactured in any desired length, wall thickness, or diameter. The construct...
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5891192 |
Ion-implanted protein-coated intralumenal implants
Ion-implanted protein-coated occlusion coils are described which have essentially the same dimensions as untreated coils and exhibit altered surface properties, e.g., thrombogenicity, endothelial...
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5591225 |
Composite artificial blood vessel
An artificial blood vessel comprising a tube of a porous synthetic polymer on a surface of which a protein or a peptide having cell adhesion and growth functions is covalently bonded through...
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5584877 |
Antibacterial vascular prosthesis and surgical suture
An antibacterial vascular prosthesis obtained by winding a tube, fiber or sheet formed from a polymeric material and combined with an antibacterial substance on the outer surface of a vascular...
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5578073 |
Thromboresistant surface treatment for biomaterials
A biomaterial with a thromboresistant surface and a method for forming same are provided. The thromboresistant surface is comprised of a distinct coating layer of a chitosan-based membrane and a...
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5554182 |
Method for preventing restenosis
An intraluminal stent comprising fibrin and heparin is capable of providing a treatment of restenosis.
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5549664 |
Artificial blood vessel
An artificial blood vessel which has excellent long-term patency and can be used stably in a living body for a long time. The artificial blood vessel has improved durability under pulsation and can...
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5383928 |
Stent sheath for local drug delivery
This invention provides a sheath for encompassing at least a portion of a stent to locally deliver a drug to an arterial wall or lumen into which the stent has been inserted, comprising a polymer...
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5370681 |
Polyumenal implantable organ
A polylumenal implantable device comprises a body defining a plurality of capillary lumina. The prosthetic device is suitable for implantation in a patient as an arterial or venous bypass graft or...
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5336256 |
Elastomeric polypeptides as vascular prosthetic materials
A vascular prosthetic material having at least one layer containing an elastomeric material capable of reversibly contracting and relaxing by an inverse temperature transition.The vascular...
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5236447 |
Artificial tubular organ
An artificial tubular organ composed of a tubular supporting frame made of a plastic material which is provided on at least one surface therefore with a medical prosthetic material. The supporting...
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5211657 |
Laminin a chain deduced amino acid sequence, expression vectors and active synthetic peptides
The present invention relates to peptides and derivatives thereof having laminin-like activity. The invention further relates to pharmaceutical compositions containing these peptides, to antibodies...
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5152784 |
Prosthetic devices coated with a polypeptide with type IV collagen activity
A polypeptide having the following formula is provided: gly-glu-phe-tyr-phe-asp-leu-arg-leu-lys-gly-asp-lys which can bind heparin and promote cellular adhesion.Medical devices such as prosthetic...
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5064430 |
Polynonapeptide bioelastomers having an increased elastic modulus
A polynonapeptide of the formula: --X--(αβγδεθλπρ)n Y--wherein: α is a peptide-forming residue of L-Valine or another peptide-forming residue capable of functioning in position i of a β-turn in...
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5007925 |
Prosthetic devices coated with polypeptides with type IV collagen activity
A composition which can bind heparin and promote cellular adhesion is provided which consists essentially of a polypeptide of the formula:...
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4960423 |
Method of enhancing the attachment of endothelial cells on a matrix and vascular prosthesis with enhanced anti-thrombogenic characteristics
The attachment and growth of endothelial cells on the luminal surface of a vascular prosthesis are enhanced by coating the luminal surface of the vascular prosthesis with peptide derived from...
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4879135 |
Drug bonded prosthesis and process for producing same
There is disclosed an improved prosthesis coated, respectively, with an anionic surfactant, a drug such as an antibiotic and/or antithrombotic agent. Optionally, the coated prosthesis may be...
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4870160 |
Polypeptides with laminin activity
A composition which can bind heparin and promote cellular adhesion is provided which consists essentially of a polypeptide of the formula: arg-tyr-val-leu-pro-arg- This invention was made with...
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4822361 |
Tubular prosthesis having a composite structure
A tubular prosthesis having a composite structure comprising (i) tubular polytetrafluoroethylene having a microfibrous structure comprising small nodes interconnected with fibrils and (ii)...
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4661111 |
Polypeptide
A polypeptide having the cell-attaching activity of fibronectin. The polypeptide has 108 amino acid residues and the formula:...
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4589882 |
Enzymatically crosslinked bioelastomers
A method of repairing a natural elastic system in a human or animal body, which comprises replacing a damaged portion of the system with a shaped artificial elastomeric copolymer comprising an...
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