Matches 1 - 45 out of 45
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7326238 Method and apparatus for treating vulnerable plaque  
An apparatus and method to treat vulnerable plaque. In one embodiment, the apparatus has a medical device to treat an occlusive plaque, and is also adapted to release a biologically active agent to...
7235096 Implantable device for promoting repair of a body lumen  
An implantable stent having surface features adapted to promote an organized growth pattern of infiltrating cells when implanted in a tubular organ is provided. The surface features comprise...
7179287 Bioreactor mediated recellularization of natural and tissue engineered vascular grafts  
Processes for producing a tissue graft comprising acellularizing or devitalizing a tubular tissue to produce a tissue matrix. The tissue matrix is then populated with at least some viable cells....
7175658 Artificial vascular grafts, their construction and use  
The present invention relates to artificial vascular grafts, methods for manufacturing and uses for them. The grafts are coated on their lumen with UP50. The grafts comprise an inner surface on...
7169764 Promoter for smooth muscle cell expression  
Disclosed is a smooth muscle cell specific promoter, the SM22α gene promoter as well as the murine cDNA and genomic SM22α nucleic acid sequences. Also disclosed are methods of preventing...
7147846 Prosthetic grafts  
An improved prosthetic graft for the bypass, replacement or repair of vessels and organs that are in contact with blood flow is disclosed. The prosthetic graft includes a porous prosthetic implant...
7112218 Tissue engineered blood vessels and apparatus for their manufacture  
The invention is a tissue engineered blood vessel (TEBV) made from a cultured fibroblast sheet rolled into a multilayer vessel which has sufficient burst strength to withstand physiological blood...
7108717 Stent covered with heterologous tissue  
A covered stent assembly comprising a tubular, expandable stent having a metallic framework covered with a cylinder of biocompatible, non-thrombogenic expandable material, such as heterologous...
7056337 Natural tissue stent  
A medical implant made from multiple layers of non-synthetic, natural tissues is provided. The medical device includes openings that extend radially through the wall of the medical implant. One...
6926743 Biological stent-graft  
A biological stent-graft and a method of making the same wherein a stent is surgically implanted in the lumen of an artery of a mammal, harvesting the stent-graft precursor after the stent has been...
6709467 Arterial prosthesis  
The arterial prosthesis is produced based on weaving technology using biologically inert polyester and polyuretan yarns, braided in a complicated structure. Then the prosthesis is impregnated with...
6579313 Methods for implanting cells  
A method for implanting cells onto a prosthesis includes the steps of: (a) providing a prosthesis including a porous tube, where at least 25% of the pores on the inner surface of the tube have...
6544249 Biological microfistula tube and implantation method and apparatus  
The present invention provides a microfistula tube including a soluble duct, defining a drainage canal having an inner surface, the duct being biocompatible, wherein the microfistula tube is coated...
6503273 Tissue engineered blood vessels and methods and apparatus for their manufacture  
The invention is a tissue engineered blood vessel (TEBV) made from a cultured fibroblast sheet rolled into a multilayer vessel which has sufficient burst strength to withstand physiological blood...
6355055 Endovascular support device and method of use  
An endovascular support device adapted for local delivery of a therapeutic agent and for minimizing the rate of restinosis having a cylindrical support body with an inside surface and an opposite...
6187039 Tubular submucosal graft constructs  
An easy-to-produce and mechanically strong tube of an implantable submucosal tissue has been developed which is manufactured in any desired length, wall thickness, or diameter. The construct...
6176874 Vascularized tissue regeneration matrices formed by solid free form fabrication techniques  
Solid free-form fabrication (SFF) methods are used to manufacture devices for allowing tissue regeneration and for seeding and implanting cells to form organ and structural components, which can...
6117979 Process for making a bioprosthetic device and implants produced therefrom  
Bioprosthetic devices made of collagen-based material having collagen amine groups and collagen carboxyl groups are provided as well as methods for their formation. The methods comprise combining...
6117166 Apparatus and methods for grafting blood vessel tissue  
Apparatus and methods especially useful for facilitating grafting of healthy blood vessel tissue onto the internal wall of a blood vessel are described. In one embodiment, the apparatus includes a...
6087552 Method of producing fused biomaterials and tissue  
It is a general object of the invention to provide a method of effecting tissue repair or replacement using a biomaterial. It is a specific object of the invention to provide a biomaterial suitable...
6060640 Multiple-layer, formed-in-place immunoisolation membrane structures for implantation of cells in host tissue  
A permeable structure forms a chamber to hold living cells. The structure includes a first permeable region surrounding at least a portion of the chamber having a conformation that, when implanted...
5575815 Local polymeric gel therapy  
A method for providing a synthetic barrier made of biocompatible polymeric materials in vivo which involves application of a material to a tissue or cellular surface such as the interior surface of...
5549700 Segmented prosthetic articulation  
A ball and socket prosthetic joint device. A plurality of curved rigid segments are embedded within and extend out of a polymeric cushion to form a discontinuous hemispherical bearing surface for...
5492826 Apparatus and method for seeding endothelial cells  
An apparatus and method for culturing living endothelial cells is provided. The apparatus comprises a cell growth container, which in a preferred embodiment is a synthetic graft, heat crimped at...
5383928 Stent sheath for local drug delivery  
This invention provides a sheath for encompassing at least a portion of a stent to locally deliver a drug to an arterial wall or lumen into which the stent has been inserted, comprising a polymer...
5230693 Implantable prosthetic device for implantation into a human patient having a surface treated with microvascular endothelial cells  
The present invention provides a synthetic or naturally occurring implant, such as a vascular graft, for implantation into a human patient. Uncultured, microvascular endothelial cells, isolated...
4932964 Artificial body for a prosthesis  
A prosthesis wall for an artificial organ, e.g. an artificial arterial blood vessel, to be coated without gaps on one side with biologically active epithelial, e.g. endothelial cells is provided...
4902289 Multilayer bioreplaceable blood vessel prosthesis  
Process for forming a multilayer blood vessel prosthesis. Each layer is formed from bioreplaceable materials which include those produced by contacting collagen with an aminopolysaccharide and...
4820626 Method of treating a synthetic or naturally occuring surface with microvascular endothelial cells, and the treated surface itself  
The present invention provides a novel method of treating a synthetic or naturally occurring implant, such as a vascular graft, intended for implantation in a human patient, comprising obtaining...
4804382 Artificial vessel  
The artificial vessel has a membrane of at least semi-permeable bio-inert synthetic material with a monolayer of endothelial cells on the internal surface and a layer of smooth elastic...
4795459 Implantable prosthetic device with lectin linked endothelial cells  
An implantable prosthetic device made of biocompatible polymer and having a substantially continuous layer of autologus living cells attached via oligosaccharidelectin recognition linkages.
4686098 Encapsulated mouse cells transformed with avian retrovirus-bovine growth hormone DNA, and a method of administering BGH in vivo  
Recombinant DNA constructs having an avian retroviral long terminal repeat (LTR) ligated to the bovine growth hormone gene, were co-transformed into a mammalian cell (mouse) culture in order to...
4681588 Biomaterial  
Material for use in a biological environment is produced by subjecting a sheet of parietal pleura to glutaraldehyde tanning. The pleura is stretched and cleansed of excessive tissue to result in a...
4662885 Percutaneously deliverable intravascular filter prosthesis  
An intravascular prosthesis comprises a lining rolled upon itself around an axis so that it is introducible into a vascular lumen. An inflatable channel is included for unrolling the lining when...
4648881 Implantable biological tissue and process for preparation thereof  
A process for the preparation of implantable biological tissue, and in particular bioprosthetic heart valves, which are prone to calcification after implantation. The process includes treatment of...
4575372 Intraocular lens and method of manufacture using ultrasonic bonding  
An intraocular lens loop, with an eyelet formed on the loop, and a method of forming the eyelet employing ultrasound energy. There is also disclosed a special fixture for use in manufacturing the...
4553272 Regeneration of living tissues by growth of isolated cells in porous implant and product thereof  
A method of repair of patient tissues by implant including providing a living cell sample which is introduced into an implant member having a porous open structure. The cell sample may be cultured...
4502159 Tubular prostheses prepared from pericardial tissue  
Novel tubular prostheses, e.g. vascular or ureteral prostheses, prepared by sewing the opposed edges of a sheet of pericardial tissue together with a thread to form a longitudinal seam are...
4485097 Bone-equivalent and method for preparation thereof  
A bone-equivalent, useful in the fabrication of prostheses, is disclosed which is prepared from a hydrated collagen lattice contracted by fibroblast cells and containing demineralized bone powder.
4485096 Tissue-equivalent and method for preparation thereof  
A tissue-equivalent, useful in the treatment of burns or other skin wounds and in the fabrication of prostheses, is disclosed which is prepared from a hydrated collagen lattice contracted by a...
4466139 Vascular prostheses  
A vascular prosthesis is produced by subjecting a length of animal ureter to glutaraldehyde tanning. The lumen of the ureter is dilated and the ureter is set in the dilated configuration by the...
4309776 Intravascular implantation device and method of using the same  
An intravascular device having a chamber for containing transplanted cells. The device is adapted to be implanted in a wall of a blood vessel with a porous chamber-forming wall of the chamber...
3974526 Vascular prostheses and process for producing the same  
A process for producing tubular prostheses for use in vascular reconstructive surgery is described. The invention comprises chemically and structurally modifying the veins and arteries of the human...
3938524 Compliant mandrel and mandrel assembly for growing graft tubes  
A mandrel of sponge rubber or gel has a tension element for withdrawing the mandrel from a graft tube grown from living tissue. In a first embodiment the tension element comprises a strip of cloth...
3894530 Method for repairing, augmenting, or replacing a body conduit or organ  
The umbilical cord is used for grafts in the vascular system or other body conduits, such as the ureter.
Matches 1 - 45 out of 45