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7620451 Methods and apparatus for pulsed electric field neuromodulation via an intra-to-extravascular approach  
Methods and apparatus are provided for pulsed electric field neuromodulation via an intra-to-extravascular approach, e.g., to effectuate irreversible electroporation or electrofusion, necrosis...
7616993 Heart stimulator using a Bezier function to define AV-delay values  
A heart stimulator provides for a more appropriate yet simple setting of the AV-delay. The heart stimulator comprises a stimulation pulse generator adapted to generate electric stimulation pulses...
7616992 Intravascular medical device  
An implantable medical device is configured so that all of the major components including a housing and attached leads are disposed within the vasculature of a patient. A tether extends from the...
7616991 Method for digital cardiac rhythm management  
A cardiac rhythm management apparatus includes a proximal housing, a distal housing and a lead. The proximal housing includes a first energy storage device. The distal module is implantable within...
7615010 System for monitoring the physiologic parameters of patients with congestive heart failure  
A telemetric sensing system for monitoring physiological parameters for diagnosis and treatment of congestive heart failure in a patient. This system includes one or more implantable sensing...
7613511 Implantable vagal stimulator for treating cardiac ischemia  
A device and method for treating cardiac ischemia with vagal stimulation is disclosed. In one embodiment, an implantable device is configured to deliver vagal stimulation upon obtaining an...
7610092 Leadless tissue stimulation systems and methods  
Systems including an implantable receiver-stimulator and an implantable controller-transmitter are used for leadless electrical stimulation of body tissues. Cardiac pacing and arrhythmia control is...
7603172 System and method of using regression models to estimate vulnerable periods for heart stimulation parameters  
Heart stimulator that provides for timing a premature stimulation pulse for anti-tachycardia pacing outside the vulnerable phase of a ventricle, to terminate stable ventricular tachycardia while...
7599741 Systems and methods for improving heart rate kinetics in heart failure patients  
Adaptive rate pacing for improving heart rate kinetics in heart failure patients involves determining onset and sustaining of patient activity. The patient's heart rate response to the sustained...
7599740 Ventricular event filtering for an implantable medical device  
Pacing parameters are provided to address cross talk and intrinsic ventricular events occurring within a predefined blanking period following an atrial event. The parameters are used in conjunction...
7599739 Multi-chamber timing for premature cardiac pacing  
A pacing control is used in multi-chamber cardiac potentiation therapy to provide a first premature pacing pulse to a first chamber based on a previous event sensed in the first chamber, and to...
7599738 Synchronized ventricular pacing to promote atrial sensing  
Methods and systems are described that involve synchronized ventricular pacing that promotes sensing of atrial events. The atrioventricular pacing delay is modified based on characteristics of...
7593773 Implantable medical device with ventricular pacing protocol including progressive conduction search  
An implantable medical device operates to promote intrinsic ventricular depolarization according to a pacing protocol. The medical device operates to promote intrinsic conduction by providing...
7590448 Method and apparatus for prevention of atrial tachyarrhythmias  
A multi-site atrial pacemaker capable of delivering pacing pulses to one location synchronized to sensed or paced atrial depolarizations on another location and a method of its use. A defined...
7590446 Methods for ventricular pacing  
An exemplary method includes determining an atrial to ventricular activation time for a right ventricle; determining an atrial to ventricular activation time for a left ventricle; and determining a...
7587240 Atrial capture verification  
Methods and systems for classifying cardiac responses to pacing stimulation and/or preventing retrograde cardiac conduction are described. Following delivery of a pacing pulse to an atrium of the...
7587239 Cardiac pacemaker system, lead and method for rejecting far-field signals  
An implantable cardiac lead comprises a lead body having a proximal end and a distal end, the proximal end of the lead body carrying a connector assembly connectable to an implantable medical...
7587238 Combined neural stimulation and cardiac resynchronization therapy  
Methods and devices for delivering cardiac therapy to a patient are provided. Various implantable device embodiments comprise a plurality of leads and a controller. The leads include at least one...
7583995 Temporary disablement feature for implantable device with anti-tachyarrhythmia functions  
An implantable cardiac rhythm management device for delivering anti-tachyarrhythmia therapy is provided with a temporary disablement feature so that the delivery of anti-tachyarrhythmia therapy may...
7580749 Method for monitoring end of life for battery  
A system is described. The system includes a lithium battery, a charge storage capacitor electrically connected to the lithium battery, a first device, and at least one second device. The first...
7580744 Classification of supraventricular and ventricular cardiac rhythms using cross channel timing algorithm  
A system and method for classifying cardiac complexes sensed during a tachycardia episode. A first cardiac signal and a second cardiac signal are sensed, where the first cardiac signal has a...
7577479 Methods and devices for implementing time of day pacing adjustments  
Methods and systems are directed to delivering cardiac pacing therapy to a patient. A pacing therapy associated with one or more pacing parameters is delivered. Alternate cardiac pacing therapies...
7574258 Cardiac therapy triggered by capture verification  
The present invention provides methods and systems for tachyarrhythmia therapy involving pacing the heart to prior to the application of a cardioversion/defibrillation shock. One or more pace...
7570996 Complex-shaped ceramic capacitors for implantable cardioverter defibrillators and method of manufacture  
An improved manufacturing and packaging process for optimizing the size of various implanted medical devices is disclosed. Specifically, complex shapes involving ceramic capacitors with various...
7567838 Method for sensing cardiac contractile function using a lead insertable motion sensor  
Systems and methods for detecting and measuring cardiac contractile function of a heart using an acceleration sensor unit inserted within the heart, such as within a vein of the cardiac wall are...
7565196 System and method for promoting intrinsic conduction through atrial timing  
An atrial based pacing protocol promotes intrinsic conduction. An entire cardiac cycle is monitored for ventricular activity and permitted to lapse with ventricular activity. Ventricular pacing is...
7558626 Cardiac resynchronization via left ventricular pacing  
The invention is directed to techniques for providing cardiac resynchronization therapy by synchronizing delivery of pacing pulses to the left ventricle with intrinsic right ventricular...
7555341 System to treat AV-conducted ventricular tachyarrhythmia  
Various aspects of the present subject matter provide devices and methods to treat AV-conducted ventricular tachyarrhythmia (AVCVT). According to various embodiments of the method, an AVCVT is...
7555340 Electrogram morphology-based CRT optimization  
A method and system for determining an optimum atrioventricular delay (AVD) interval and/or ventriculo-ventricular delay (VVD) intervals for delivering ventricular resynchronization pacing in an...
7555336 Automatic LV/RV capture verification and diagnostics  
The present invention provides a technique for verifying pacing capture of a ventricular chamber, particularly to ensure desired delivery of a ventricular pacing regime (e.g., cardiac...
7551962 Implantable medical device with voice responding and recording capacity  
An implantable medical device such as a cardiac pacemaker or implantable cardioverter/defibrillator with the capability of receiving communications in the form of speech spoken by the patient. An...
7551961 Cardiac stimulation device with selective atrial pacing on premature ventricular complex detection and method  
An implantable cardiac stimulation device provides selective atrial pacing upon detection of a premature ventricular complex (PVC). The device comprises a premature ventricular complex detector...
7548782 Method for reversal of myocardial remodeling with electrical stimulation  
A method for reversing ventricular remodeling with electro-stimulatory therapy. A ventricle is paced by delivering one or more stimulatory pulses in a manner such that a stressed region of the...
7548780 Cell therapy and neural stimulation for cardiac repair  
A method and system to enhance cell, gene and/or cytokine therapy for cardiac repair in a mammal.
7547301 Device and method to slow or stop the heart temporarily  
Implantable cardiac drug delivery systems. The systems are installed endocardially into a chamber in the heart, and are variously capable of delivering anti-arrhythmia agents into the heart wall,...
7546162 Automatic selection of stimulation chamber for ventricular resynchronization therapy  
A method and apparatus for selection of one or more ventricular chambers to stimulate for ventricular resynchronization therapy. Intrinsic intracardia electrograms that include QRS complexes, are...
7546161 Methods for loss of capture and fusion avoidance in biventricular pacing therapy  
An exemplary method includes delivering biventricular pacing therapy using one or more timing parameters, detecting loss of capture, deciding if fusion exists without adjusting the one or more...
7546160 Reduction of interaction with tachyarrhythmia detection by negative offset pacing  
A device and method is disclosed for improving tachyarrhythmia detection when the ventricles are resynchronized by delivering paces to both ventricles separated by a specified negative offset...
7542807 Conduction block verification probe and method of use  
Devices and methods provide for ablation of cardiac tissue for treating cardiac arrhythmias such as atrial fibrillation. Although the devices and methods are often to be used to ablate epicardial...
7542800 Method and apparatus for synchronizing neural stimulation to cardiac cycles  
A neural stimulator senses a reference signal indicative of cardiac cycles each including a predetermined type timing reference event using a sensor external to the heart and blood vessels. The...
7542799 Implantable medical device with ventricular pacing protocol  
An implantable medical device operates to promote intrinsic ventricular depolarization according to a pacing protocol. The medical device determines a course of action based upon the presence or...
7536223 Mode transition timing for synchronized pacing  
A system and method for avoiding short-interval paces during pacing mode transitions. The method may be particularly useful in switching to or from a biventricular pacing mode.
7532930 Cardiac pacemaker  
Certain embodiments of the present invention disclose an electrostimulator, in particular an atrial cardiac pacemaker, comprising electrode connections which are connected to a stimulation unit for...
7532929 Adaptive ventricular rate smoothing during atrial fibrillation  
An implantable cardiac device is provided for adaptive ventricular rate smoothing during atrial fibrillation (AF). When AF is detected, the operation of the device is switched to non-atrial...
7529585 Method and apparatus for optimizing ventricular synchrony during DDD resynchronization therapy using adjustable atrio-ventricular delays  
A pacing system for providing optimal hemodynamic cardiac function for parameters such as ventricular synchrony or contractility (peak left ventricle pressure change during systole or LV+dp/dt), or...
7529584 Pacing method  
A method for delivering physiological pacing includes selecting an electrode implant site within an interventricular septal zone, which is in proximity to the bundle of His where pacing stimulation...
7526336 Left heart implantable cardiac stimulation system with clot prevention and method  
An implantable cardiac stimulation device provides pacing stimulation therapy from within the left ventricle of a heart. The device includes a pulse generator adapted to be coupled to an...
7519423 Dual-chamber pacemaker system for simultaneous bi-chamber pacing and sensing  
A method of pacing opposing chambers of a heart with a pacing system is provided. The pacing system comprises a first bipolar medical electrical lead having at least one first electrode configured...
7519422 Electrotherapy device  
Certain embodiments of the present invention disclose an implantable electrotherapy device comprising a housing in which are arranged an activity sensor, an impedance or conductivity measuring unit...
7515958 System and method for altering pacing modality  
An implantable medical device operates according to a ventricular pacing protocol (VPP) that precludes ventricular pacing in any cardiac cycle where a sensed ventricular event has occurred in the...