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5720894 Ultrashort pulse high repetition rate laser system for biological tissue processing  
A method and apparatus is disclosed for fast, efficient, precise and damage-free biological tissue removal using an ultrashort pulse duration laser system operating at high pulse repetition rates....
5710148 Corneal opacification inhibitory composition  
An ophthalmic preparation which comprises a fumagillol derivative represented by the general formula(I): ##STR1## wherein R 1 is hydrogen; R 2 is a halogen, N(O) m R 5 R 6 , N + R 5 R 6 R 7 ...
5707403 Method for the laser treatment of subsurface blood vessels  
The invention provides a method for selectively destroying blood vessels contained at a selected depth and in a selective area of a patients dermis by positioning a laser so that light from the...
5693049 Method and apparatus for in vivo blood irradiation  
In vivo irradiation of blood is performed via catheters which can also or alternately be used to introduce fluids into blood vessels. The catheters include narrow tubular portions which are at...
5662646 Method and apparatus for laser surgery  
An apparatus for use with a laser surgical tool comprises an elongate substantially hollow sheath having a pair of spaced apart axially extending guide members on a distal end and an attaching...
5649924 Medical device for irradiation of tissue  
A medical device applies localized heat to a site in a patient's body by irradiation with light and by conduction. The device includes a radiant energy transmitting conduit, typically an optic...
5643334 Method and apparatus for the diagnostic and composite pulsed heating and photodynamic therapy treatment  
The present invention is directed toward an apparatus and method for diagnostic and composite treatment of a wide range of solid tumors. More particularly, the invention relates to an efficient...
5634920 Method and apparatus for removing epithelium from the surface of the eye  
A apparatus and method for controlling an apparatus for removing tissue from the eye performs various types of corrections using a relatively large beam, but oscillating, or dithering, that being...
5634922 Cancer diagnosis and treatment device having laser beam generator  
A cancer diagnosis and treatment device comprising a solid-state laser generator such as an Nd-YAG laser, an alexandrite laser, or titanium sapphire laser for emitting a first laser beam having a...
5632767 Loop diffusers for diffusion of optical radiation  
Methods and apparatus are disclosed for diffusing radiation from a optical fiber to provide a larger exposure area for phototherapy and to provide a substantially uniform energy distribution to a...
5628744 Treatment beam handpiece  
A dermatology handpiece delivers a treatment beam of optical energy to a lesion. The handpiece has the ability to selectively determine whether or not the treatment beam is delivering optical...
5624432 Illuminating bougie and methods for diagnostic, therapeutic and surgical procedures  
An illuminated bougie in which the elongate bougie body is formed of flexible light-transmitting material. A socket for detachably attaching the light-transmitting end of a fiber optic bundle is...
5609591 Laser balloon catheter apparatus  
A laser balloon catheter apparatus emits laser light, received through optical fiber, via a balloon for irradiating tissue. It includes a laser light emitting means, a coolant supply passage...
5580555 Regeneration of injured central nervous system axons  
Administration of tumor necrosis factor to the site of injured central nervous system axons will result in facilitation of the regeneration of axons across the site of the injury. Recombinant human...
5568503 Solid-state laser device with optical fiber cable connection  
This invention has as its object to provide a solid-state laser device which can supply a laser beam pumped by a solid-state laser medium from the distal end of an optical fiber. In order to...
5534000 Laser fiber apparatus having a contact tip and adjacent diffuser element and surgical methods for using same  
An improved laser fiber assembly is provided which is capable of both effecting direct ablation of tissue or of effecting deep tissue coagulation. The fiber assembly is preferably provided with an...
5531738 Process for operating a laser  
For an interstitial thermotherapeutic treatment of biological tissue in which, for generating a coagulation necrosis, the radiation of the laser within a radiation period is guided into the tissue...
5527350 Pulsed infrared laser treatment of psoriasis  
A method for treating psoriasis with pulsed infrared laser illumination. A pulsed infrared diode laser having a wavelength of 800 nm and a pulse duration in the millisecond range selectively...
5514168 Treatment of vascular headache and atypical facial pain  
A new method of treatment of vascular headaches (migraine, cluster) as well as atypical pain is presented, comprising the application of bursts of low power laser light to the area of intra-oral...
5507739 Dental laser  
A dual wavelength laser is disclosed for use in dental therapeutic applications. The dual wavelength laser includes a laser cavity in which a laser crystal is disposed and preferably the laser...
5505725 Shapeable optical fiber apparatus  
A shapeable optical fiber apparatus includes an optical fiber, a support structure secured over a distal end portion of the optical fiber, and terminates in a lens at its distal end. The transition...
5505726 Article of manufacture for the photodynamic therapy of dermal lesion  
An article of manufacture for photodynamic therapy of a dermal lesion located at a dermal treatment site on skin including the stratum corneum, transparent hydrogel for covering the dermal...
5489279 Method of applying photodynamic therapy to dermal lesion  
Method of applying photodynamic therapy to dermal lesion located at a dermal treatment site in skin which includes the stratum corneum, including the steps of hydrating the stratum corneum at the...
5486170 Medical catheter using optical fibers that transmit both laser energy and ultrasonic imaging signals  
A medical catheter which includes one or more optical fibers, each of which transmits both ultrasonic signals for imaging of the treatment area and laser energy for treatment of a medical...
5467767 Method for determining if tissue is malignant as opposed to non-malignant using time-resolved fluorescence spectroscopy  
A method for determining if tissue is malignant as opposed to non-malignant (i.e., benign tumor tissue, benign tissue, or normal tissue). In one embodiment, the method comprises irradiating a human...
5464436 Method of performing laser therapy  
A method of treating a patient, includes providing a laser source for emitting a laser light, diagnosing an afflicted area of the patient, delivering the laser light to the afflicted area for at...
5454782 Translumenal circumferential energy delivery device  
A probe for translumenal circumferential delivery of energy through a biological lumen comprises a catheter which is constructed and arranged to be placed within a particular biological lumen. A...
5445146 Biological tissue stimulation by low level optical energy  
Biological tissue of a living subject is irradiated with optical energy at a wavelength and at a power dissipation level to cause the amount of optical energy absorbed and converted to heat in the...
5445608 Method and apparatus for providing light-activated therapy  
Light developed by an implantable probe is used to illuminate a treatment site that has been perfused with a photoreactive agent. A number of different embodiments of implantable probes are...
5427095 Method and apparatus for detecting cataractogenesis  
A method and an apparatus are disclosed for using quasielastic light scattering to determine the degree of cataractogenesis of a lens in vivo. By collecting and analyzing light scattered from the...
5417653 Method for minimizing restenosis  
Disclosed is a light angioplasty catheter and method for exposing the interior of a body lumen to a source of light. Light exposure may be accomplished prior to, during, or following conventional...
5409482 Probe, and method of use thereof for biomodulation of tissue, nerve and immune systems  
The probe for biomodulation is disclosed. The probe includes a semiconductor laser and a drive circuit which causes the laser to generate pulses in bursts. The pulses themselves are of nanosecond...
5409483 Direct visualization surgical probe  
A surgical probe for use in a hollow vessel or other region of the body which comprises a multi-lumen catheter having a transparent, non-compliant balloon coupled to the distal end, such that the...
5409480 Laser endoscope system console  
An endoscope laser system console including a chassis having a front wall, a rear wall, and a first side wall connecting the front and rear walls; an interior wall connected to the rear wall and...
5403307 Apparatus, system, and method for softening and extracting cataractous tissue  
A laser may be used to soften the cataractous tissue prior to removal with the wedge-tipped probe. The cataract softening or other laser energy used during the surgical procedure being performed...
5395362 Methods and apparatus for distributing laser radiation  
Apparatus and methods are disclosed for distributing and delivering laser radiation with substantially uniform intensity to multi-spatial locations. Laser radiation is directed into a fiber optic...
5390204 Intracavity modulated pulsed laser with a variably controllable modulation frequency  
An intracavity modulated pulsed laser comprising an amplification medium, a pulsed pumping source, a beam modulator, and two mirrors, one totally reflective and one partially reflective for...
5387211 Multi-head laser assembly  
A laser device is provided for the co-axial positioning of plural laser beams of same or different wavelengths along a single axis. At least two laser oscillators are provided, each producing a...
5380317 Medical device applying localized high intensity light and heat, particularly for destruction of the endometrium  
A medical device applies localized heat to a site in a patient's body by irradiation with light and by conduction. The device includes a radiant energy transmitting conduit, typically an optic...
5368031 Magnetic resonance surgery using heat waves produced with a laser fiber  
Surgery is performed with pulsed heat means that selectively destroys tissue in a region within a patient. The size of the region destroyed is dependent upon the frequency of the pulses of the...
5360426 Force-controlled contact applicator for laser radiation  
A contact applicator arrangement for applying laser radiation to an object is disclosed. The contact applicator arrangement includes: a holder having an outer surface and defining a longitudinal...
5360447 Laser assisted hair transplant method  
A hair transplant procedure is described which includes preparing a plurality of hair plugs from a donor site on the scalp. A corresponding number of incisions are drilled into the hairless...
5354324 Laser induced platelet inhibition  
A method for preventing platelet adhesion to a vascular surface in a mammal, which includes irradiating the vascular surface with a pulse of laser energy having a pulse duration less than the...
5354323 Optical heating system  
A laser heating system projects a beam of optical radiation on a region to be heated. A sensor detects changes in temperature of the region by sensing the black body radiation of the heated region....
5350376 Optical controller device  
An improved configuration for a surgical laser instrument to provide the alternate contact cutting and no-contact coagulating of biological tissues by means of a fiber-optically guided irradiation...
5346488 Laser-induced ablation of atherosclerotic plaque  
A method of ablating atherosclerotic plaque by means of short-duration laser light pulses. A carotenoid, such as beta-carotene, is preferably administered to the patient by injection or ingestion...
5344434 Apparatus for the photodynamic therapy treatment  
The invention relates to an apparatus for an efficient photodynamic therapy treatment. The apparatus comprises the following parts: (a) a lamp possessing a narrow beam light with half angle...
5342350 Method of endoscopically treating lithiases with a multichannel probe suitable for draining the treated lithiases  
A multichannel probe comprising a hollow tube defining a distal end and a proximal end, the tube being made of a flexible self-supporting material enabling the tube to fold or to be curved, and...
5342353 System for laser treatment of the female urethra and bladder  
A CO2 laser system which includes the CO2 laser unit, a microscope for receiving the laser beam and directing the beam to the infected area; a modified air cystoscope which further comprises a...
5336217 Process for treatment by irradiating an area of a body, and treatment apparatus usable in dermatology for the treatment of cutaneous angio dysplasias  
The invention relates to a process of treatment in the field of dermatology, for the treatment of cutaneous angio dysplasias, using the energy emitted by a laser source, as well as to an apparatus...