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7590449 Patient signaling method for treating cardiovascular disease  
A method of treating cardiovascular disease in a medical patient is provided. The method includes the steps of generating a sensor signal indicative of a fluid pressure within the left atrium of...
7580746 Implantable medical device for generating cardiac pressure-volume loop and optimizing therapy  
An implantable medical device for generating a cardiac pressure-volume loop, the implantable medical device comprising a pulse generator including control circuitry, a first cardiac lead including...
7529583 Therapeutic device and method using feedback from implantable pressure sensor  
Devices and methods to reduce the incidence of both false positive and false negative detection of rhythm anomalies. Implantable devices that measure vascular pressure, vascular blood flow, tissue...
7526338 Implantable cardiac device for monitoring diastolic heart failure and method of operation and use thereof  
An implantable cardiac device is used to measure one or more parameters relating to cardiac activity of a patient's heart, from which diastolic heart failure (“DHF”) may be monitored and/or...
7493164 Application of blood pressure profile parameter to assess circadian state of patients  
A monitoring and/or stimulation device to receive a signal from a lead sensor positioned in the heart of patient. The monitoring and/or stimulation device processes the blood pressure data received...
7483742 Detection of diastolic heart failure  
An implantable medical apparatus for detecting diastolic heart failure, DHF, has a DHF determining device for determining at least one blood pressure parameter for detecting a DHF state of the...
7460909 Implantable device for monitoring hemodynamic profiles  
An exemplary method includes providing a filling pressure parameter, providing a perfusion parameter, determining a hemodynamic profile based at least in part on the filling pressure parameter and...
7450989 Method and device in connection with pressure measurement  
Pressure measurement device ( 2 ) including a pressure sensor ( 6 ) adapted to perform pressure measurements in the left ventricle of a heart ( 8 ). The sensor is connected to a measurement unit (...
7437192 System and method for detecting heart failure and pulmonary edema based on ventricular end-diastolic pressure using an implantable medical device  
Techniques are provided for detecting left ventricular end diastolic pressure (LV EDP) using a pressure sensor implanted within the heart of a patient and for detecting and evaluating heart failure...
7409244 Method and apparatus for adjusting interventricular delay based on ventricular pressure  
A method and apparatus for pacing left and right ventricles of the heart involve measuring one or both of a right ventricular (RV) pressure and a left ventricular (LV) pressure, and computing a...
7409241 Monitoring the sympathico-vagal activity by analysis of endocardiac acceleration in an active implantable medical device  
An active implantable medical device having a function for monitoring the sympathico-vagal activity by an analysis of endocardiac acceleration. The device collects at least one physiological...
7392084 Demand-based cardiac function therapy  
A method and device for delivering cardiac function therapy on a demand basis. An implantable device for delivering cardiac function therapy is programmed to suspend such therapy at periodic...
7366569 Non-invasive method and apparatus for cardiac pacemaker pacing parameter optimization and monitoring of cardiac dysfunction  
A plethysmogram signal is sensed from a patient and provided to a programmer device for monitoring the condition of the patient and for optimizing pacing parameters of a cardiac device implanted in...
7364550 Method and device for motion and noise immunity in hemodynamic measurement  
A method and device, such as an implantable cardiac device, for motion and noise immunity in hemodynamic measurement is presented. The method includes obtaining a template waveform representing...
7363077 Adaptive timing interval control method for treating congestive heart failure  
A method of treating a heart with an implantable cardiac stimulation device involves transiently disturbing the steady state hemodynamic parameters by altering a cardiac cycle timing interval...
7269460 Method and apparatus for evaluating and optimizing ventricular synchronization  
A method and apparatus for determining a metric of cardiac ventricular synchronization and optimizing a cardiac therapy based on the ventricular synchronization metric are provided. A ventricular...
7260431 Combined remodeling control therapy and anti-remodeling therapy by implantable cardiac device  
A method and device for delivering ventricular resynchronization pacing therapy in conjunction with electrical stimulation of nerves which alter the activity of the autonomic nervous system is...
7225022 Method of optimizing patient outcome from cardiac resynchronization therapy  
A method of data management for optimizing the patient outcome from the provision of cardiac resynchronization therapy (CRT) is described. This method describes a process by which sets of dynamic...
7206636 Pacing optimization based on changes in pulse amplitude and pulse amplitude variability  
A signal indicative of cardiac contractions of a patient's heart is produced, as the patient's heart is paced using different sets of pacing interval parameters. Measures of pulse amplitude are...
7181283 System and method for controlling implantable medical device parameters in response to atrial pressure attributes  
In an implantable medical device a real-time left atrial pressure (“LAP”) signal obtained from a patient's heart is used as a feedback control mechanism to adjust one or more device parameters....
7177686 Using photo-plethysmography to monitor autonomic tone and performing pacing optimization based on monitored autonomic tone  
The autonomic tone of a patient is measured based on a photo-plethysmography signal that is representative of arterial pulse pressure of the patient. Such measures of autonomic tone can be used to...
7158830 Method and apparatus for optimizing stroke volume during DDD resynchronization therapy using adjustable atrio-ventricular delays  
A pacing system for providing optimal hemodynamic cardiac function for parameters such as ventricular synchorny or contractility (peak left ventricle pressure change during systole or LV+dp/dt), or...
7136705 Method and apparatus for monitoring sensor performance during rate-responsive cardiac stimulation  
A cardiac stimulation device and method monitor and store discrepancies in sensor indicated rates determined from two or more sensors generating signals related to metabolic demand. One feature...
7110817 Method and apparatus for optimizing ventricular synchrony during DDD resynchronization therapy using adjustable atrio-ventricular delays  
A pacing system for providing optimal hemodynamic cardiac function for parameters such as ventricular synchorny or contractility (peak left ventricle pressure change during systole or LV+dp/dt), or...
7069079 Pressure regulated atrio-ventricular delay for multi-site pacing  
The hemodynamic operation of certain heart disease patient can be improved using pressure regulated atrio-ventricular delay. The pressure regulated atrio-ventricular delay involves recording atrial...
7058450 Organizing data according to cardiac rhythm type  
A plurality of sensors are disposed in and around the heart of a patient to collect data such as various electrical parameters, pressure parameters and temperature parameters. The data collected...
7027866 Mechanically-based interval optimization for a biventricular pacing engine  
According to the present invention, discrete measurements of fluid pressure development (and derivatives thereof) are used in optimizing hemodynamics for cardiac resynchronization therapy (CRT)...
7024244 Estimation of stroke volume cardiac output using an intracardiac pressure sensor  
Techniques are described for estimating a rate of blood flow from a heart, such as a stroke volume or a cardiac output, as a function of a pressure in the heart. A pressure monitor may measure...
6970742 Method for detecting, diagnosing, and treating cardiovascular disease  
A method of treating cardiovascular disease in a medical patient is provided. The method includes the steps of generating a sensor signal indicative of a fluid pressure within the left atrium of...
6937902 Pacemaker with determination of the dependency of cardiac output on the AV-delay  
A cardiac pacemaker has a pulse generator for delivering stimulation pulses to a patient's heart and a control unit for controlling the delivery of the stimulation pulses from the pulse generator....
6934586 Cardiac resynchronization with adaptive A1-A2 and/or V1-V2 intervals  
In a system that provides bi-atrial and/or bi-ventricular pacing, the system adjusts an interval between paces delivered to the atria, and/or an interval between paces delivered to the ventricles,...
6915162 Implantable medical device for measuring ventricular pressure  
An implantable medical device has a pressure sensing arrangement to measure right ventricular pressure of a heart including a pressure sensor adapted to be positioned in the right ventricle of the...
6865419 Method and apparatus for measurement of mean pulmonary artery pressure from a ventricle in an ambulatory monitor  
A system and method for determining mean pulmonary arterial pressure (MPAP) using a pressure sensor located within a ventricle of a heart, and a signal indicative of cardiac electrical activity...
6792309 Multi-sensor system for controlling an implantable heart stimulator  
A multi-sensor system for controlling an implantable heart stimulator, and an implantable heart stimulator containing such a multi-sensor system, have a piezoelectric pressure sensor adapted for...
6754532 Coronary sinus flow regulated pacing  
An implantable system having a left ventricular pacing lead for implantation in the great cardiac vein via the coronary sinus of a patient's heart. The pacing lead includes a sensor for measuring...
6748271 Method and system for treatment of neurocardiogenic syncope  
A method and apparatus for treating or preventing neurocardiogenic syncope is disclosed. Upon detection of bradycardia or a drop in blood pressure indicating the onset of syncope,...
6738667 Implantable medical device for treating cardiac mechanical dysfunction by electrical stimulation  
An implantable stimulator and monitor measures a group of heart failure parameters indicative of the state of heart failure employing EGM signals, measures of blood pressure including absolute...
6719701 Implantable syncope monitor and method of using the same  
An implantable monitor and method to acquire, store, and display physiological data for the diagnosis of vasovagal syncope or intermittent cardiac arrhythmias. Physiological data monitored...
6666826 Method and apparatus for measuring left ventricular pressure  
A body implantable system employs a lead system having at least one electrode and at least one pressure transducer at a distal end. The lead system is implanted within a patient's heart in a...
6662047 Pacing mode to reduce effects of orthostatic hypotension and syncope  
An implantable cardiac stimulation device is programmed to administer pacing therapy in response to a change in a patient's position and a drop in blood pressure. The stimulation device is equipped...
6580946 Pressure-modulated rate-responsive cardiac pacing  
Techniques for pacing the heart of a patient as a function of an intra-cardiac pressure make use of a pressure monitor that receives a pressure signal from a pressure sensor in the patient's right...
6547737 Intelligent transcranial doppler probe  
A system for automatic manipulation of a transcranial Doppler probe device designed for placement on a patient's head comprising a bi-temporal probe hanger, a cylindrical probe housing having an...
6540699 System for incorporating sonomicrometer functions into medical instruments and implantable biomedical devices  
A biomedical apparatus is disclosed including an implantable biomedical device for providing biomedical assistance to the body structure and a device controller for regulating the operation of the...
6468219 Implantable telemetric transcranial doppler device  
The invention relates to a cerebral blood flow velocity monitoring system and method that comprises a transcranial Doppler ultrasound device that is adapted to be implanted in the human body, an...
6450942 Method for reducing heart loads in mammals  
A method and apparatus for treating a mammal or other living organism having a heart and a peripheral vascular system to achieve a heart load reduction, said organism having a pulse rate and a...
6371922 Method for measuring baroreflex sensitivity and therapy optimization in heart failure patients  
A method and apparatus for determining the baroreflex sensitivity in a chronic heart failure patient and a method for chronic heart therapy evaluation. The method including providing a series of...
6366811 Extraction of hemodynamic pulse pressure from fluid and myocardial accelerations  
A cardiac stimulating apparatus and method is described that non-intrusively determines an amount indicative of hemodynamic pulse pressure from an accelerometer signal. The amount indicative of...
6314323 Heart stimulator determining cardiac output, by measuring the systolic pressure, for controlling the stimulation  
A heart stimulator has a circuit for determining cardiac output and for producing a control signal corresponding to the determined cardiac output, and a controller for controlling cardiac...
6277078 System and method for monitoring a parameter associated with the performance of a heart  
An intrabody implantable system for long-term, real time monitoring of at least one parameter associated with heart performance. The system includes (a) a first sensor being implantable within a...
6233486 Ischemia detector and heart stimulator provided with such an ischemia detector  
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