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7621906 |
Method and apparatus to deliver drug and pacing therapy for treatment of cardiac disorders
A drug delivery system uses an electrically sensitive polymer to store a drug and applies an electric field onto the electrically sensitive polymer for quantitatively and temporally controlled drug...
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7596415 |
Medical devices incorporating carbon nanotube material and methods of fabricating same
The present invention relates generally to medical devices; in particular and without limitation, to unique electrodes and/or electrical lead assemblies for stimulating cardiac tissue, muscle...
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7584005 |
Steroid eluting pacing tip electrode
An implantable cardioverter defibrillator (ICD) including a set of leads having electrodes disposed therein. The electrodes may include a weld electrode connected to an internal wire of the lead...
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7547301 |
Device and method to slow or stop the heart temporarily
Implantable cardiac drug delivery systems. The systems are installed endocardially into a chamber in the heart, and are variously capable of delivering anti-arrhythmia agents into the heart wall,...
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7529592 |
Subcutaneous electrode and lead with temporary pharmacological agents
An implantable subcutaneous device and method employ a lead and an electrode for cardiac monitoring and intervention. The device includes an implantable lead having a lead body, a subcutaneous...
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7499757 |
Absorbable myocardial lead fixation system
A myocardial lead attachment system for securing a distal end of a lead within a myocardium of a patient's heart. The system includes a lead body, an anchor mechanism formed of a bioabsorbable or...
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7460914 |
Devices and methods to stimulate therapeutic angiogenesis for ischemia and heart failure
A method for stimulating angiogenesis is provided that includes the use of an electrical output channel adapted to deliver a sub-threshold voltage, a lead that includes a proximal end adapted to be...
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7421295 |
Implantable cardiac lead having removable fluid delivery port
An implantable cardiac lead includes an elongated lead body having opposed proximal and distal end portions, and a fluid delivery lumen extending therethrough. A connector assembly is operatively...
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7398126 |
Drug dispensing medical electrode lead and method for making same
In an electrically conductive lead adapted for implantation in a human or animal body, and a method for making such a lead, a drug-dispensing member is disposed at a distal end portion of the lead,...
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7386350 |
Combination electrical stimulating and infusion medical device
A combined electrical and chemical stimulation lead is especially adapted for providing treatment to intervertebral discs. The combination lead may be placed proximate to intervertebral disc...
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7366573 |
Polymer lead covering with varied material properties
This document discusses, among other things, a lead assembly including a lead body, at least one conductor extending through the lead body, and a covering having varied material properties. In an...
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7363091 |
Method of molding silicone elastomer drug carrier in an endocardial lead
A drug-eluting endocardial lead and method of manufacture. The silicone elastomer of the present invention is ideally suited to a manufacturing environment due to its extended pot life and...
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7337011 |
System and method for enhancing cardiac signal sensing by cardiac pacemakers through genetic treatment
The present invention provides delivery systems for and methods of delivering ion channel protein genetic material to cardiac cells in areas adjacent to where an electrode is to be positioned in a...
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7289856 |
Medical electrical lead containing a pyroelectric material
A medical electrical lead containing a pyroelectric material is provided. The pyroelectric material is capable of dissipating heat generated in the lead due to radio frequency energy. The...
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7282213 |
Method for applying a drug coating to a medical device
A method for coating a medical device with a drug is provided. Energy, preferably thermal energy, is applied to a crystalline deposit of a drug on the surface of a medical device to increase the...
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7274966 |
Medical fluid delivery system
A medical fluid delivery system includes an implantable medical lead including a fixation element adapted to secure the lead to a tissue site and a fluid delivery device including a tissue piercing...
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7245973 |
His bundle mapping, pacing, and injection lead
A cardiac rhythm management system includes a lead assembly for intracardiac mapping, pacing, and drug delivery. The lead assembly includes an implantable endocardial lead having a proximal end for...
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7236834 |
Electrical lead body including an in-line hermetic electronic package and implantable medical device using the same
An assembly is provided for an implantable medical lead. The assembly includes a first lead body comprising one or more electrical leads, and a hermetic encasement. The encasement comprises a...
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7211063 |
Pressure sensor for therapeutic delivery device and method
The present invention is an apparatus for treating a selected patient tissue or organ region, at the surface of such region. The apparatus has an accessing tool for accessing the patient region,...
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7209792 |
RF-energy modulation system through dynamic coil detuning
An RF-energy modulation system dynamically adjusts tuned receiving circuits within a plurality of slave devices, thereby regulating the level of power reception in each slave device. The slave...
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7203550 |
Implantable medical device with a current generated for infection control
In a cardiac stimulating device, an infection control current is generated and applied to a subject in whom a medical device is implanted by completing a circuit including an entirely electrically...
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7195776 |
Patch stabilization of rods for treatment of cardiac muscle
The present invention relates to a system and method for the delivery of therapeutic agents, such as therapeutic drugs or genetic material, into the muscle or tissue that minimizes the loss of...
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7187980 |
Cardiac lead with steroid eluting ring
A cardiac lead is disclosed which includes an elongated lead body having opposed proximal and distal ends, a tip electrode operatively associated with the distal end of the elongated lead body, a...
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7184839 |
Catheter-delivered cardiac lead
A lead for delivering electrical signals to and/or receive electrical signals from a human heart that includes a solid inner conductor, and a fixation device having a titanium nitride coated...
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7174221 |
Method of manufacturing a drug-eluting endocardial lead utilizing silicone elastomer as a drug carrier
A drug-eluting endocardial lead and method of manufacture. The silicone elastomer of the present invention is ideally suited to a manufacturing environment due to its extended pot life and...
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7155292 |
Active fixation assembly for an implantable device
An implantable device such as a lead is adapted for implantation on or about the heart and for connection to a system for monitoring or stimulating cardiac activity. The implantable device includes...
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7127302 |
Electrode lead
An intracardial electrode lead comprises a distal end, a proximal end and an elongate electrode lead body which includes a helical coil having a lumen and a sheath enclosing the helical coil. The...
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7104988 |
Cardiac drug delivery system
A system is disclosed, for administering a therapeutic agent locally and to a depth within cardiac tissue. An elongate, flexible catheter contains a flexible electric conductor and supports at its...
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7103418 |
Active fluid delivery catheter
A medical system incorporating fluid delivery and lead delivery lumens dispense fluid into a volume of tissue. The fluid comprises or contains a pharmacologic, genetic, or biologic agent. The fluid...
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7092753 |
Drug delivery device
Apparatus ( 800 ) for targeted release of a molecule carried in a circulating reservoir, comprising: at least one electrode ( 804 ); and a controller ( 810 ) adapted to electrify said electrode (...
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7031769 |
Dosage control electrode for iontophoresis device
An electrode assembly for use in an iontophoresis device for the transcutaneous administration of an active therapeutic species includes a base layer of conductive material which is consumed...
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7029466 |
Cardiac drug delivery system and method for use
Implantable cardiac drug delivery systems. The systems are installed endocardially into a chamber in the heart, and are variously capable of delivering anti-arrhythmia agents into the heart wall,...
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7013181 |
Coronary vein lead having combination fixation features with lumen restriction and method therefor
A lead assembly includes insulative tubing with at least one tine coupled thereto, and a lumen extends through the tubing. The tine has a first position that extends away from the exterior of the...
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7001372 |
Apparatus and method for treating body tissues with electricity or medicaments
A therapeutic device and therapeutic method for delivering electrical energy or a medicament to a body tissue or organ utilizing ultrasonic vibration to cause a device implanted in the body tissue...
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6978184 |
Optimization method for cardiac resynchronization therapy
The patterns of contraction and relaxation of the heart before and during left ventricular or biventricular pacing are analyzed and displayed in real time mode to assist physicians to screen...
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6965798 |
Implantable device for treating atrial fibrillation and method of using same
A device for treating atrial fibrillation includes a pad which houses the distal end of an electrode which is adapted to deliver a substantially uniform shock gradient to an atrial surface of a...
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6931286 |
Delivery of active fixation implatable lead systems
An implantable lead system includes an elongated device slideably engaged within a lumen of a lead body. A distal portion of the elongated device is slidable through a helix tip coupled to a distal...
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6889092 |
High impedance electrode assembly
A lead having an electrode assembly has a high impedance electrode. The high impedance electrode includes a partially insulated sleeve electrode or a wire filament. The high impedance electrode...
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6856840 |
Ionically conductive polymeric composition
An ionically conductive polymeric composition is disclosed. The composition is especially useful for coating an implantable hot can defibrillator electrode. The polymeric composition, for example,...
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6775570 |
Iontophoretic treatment device
A low cost, accurate, single use, disposable, iontophoretic fluid delivery device having cationic and anionic chambers separated by container structure and arranged to promote a flow of treatment...
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6748653 |
Method of making a temporary medical lead having biodegradable electrode mounting pad loaded with therapeutic drug
A method of making a temporary medical electrical lead for pacing or defibrillating a heart of a patient. The method comprises providing at least one electrical conductor having proximal and distal...
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6733485 |
Microstimulator-based electrochemotherapy methods and systems
A small implantable stimulator(s) includes at least two electrodes for delivering electrical stimulation to surrounding tissue and/or a pump and at least one outlet for delivering a drug or drugs...
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6702777 |
Apparatus and method for intracardiac therapy using sensor for heart wall thickness
Apparatus for intracardiac drug administration, including a catheter which is inserted into a chamber of the heart and brought into engagement with a site in the heart wall. The catheter includes...
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6671562 |
High impedance drug eluting cardiac lead
A high impedance bipolar cardiac lead is disclosed that includes a lead body with a distal electrode assembly that includes an anodic ring electrode and a coaxially disposed cathodic tip electrode,...
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6671561 |
Catheter with electrode having hydrogel layer
A catheter having an improved electrode that minimizes irritation to the heart tissue and counters the occurrence of foreign body reactions is provided. The catheter comprises an elongated,...
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6547787 |
Drug delivery catheters that attach to tissue and methods for their use
A drug delivery catheter suited for cardiac procedures including transmyocardial revascularization. The catheter includes a distal helical coil or other fixation and penetrating element, which can...
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6511477 |
Method of drug delivery to interstitial regions of the myocardium
A method of treating the heart and other body tissues by injecting a compound comprised of microsphere encapsulated macromolecule therapeutic agents into the myocardium, such that the microsphere...
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6405091 |
Lead assembly with masked microdisk tip electrode and monolithic controlled release device
A passive fixation, body implantable lead assembly has a cylindrical tip electrode whose outer side surface is covered with a thin dielectric insulating layer so as to mask an active, disk-shaped...
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6385491 |
Temporary medical electrical lead having biodegradable electrode mounting pad loaded with therapeutic drug
A temporary cardiac electrical stimulating lead comprises a stimulating electrode mounted in or on a biodegradable electrode mounting pad disposed at a distal end of the lead. The electrode...
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6370427 |
Method and apparatus for dual chamber bi-ventricular pacing and defibrillation
Device and method are disclosed in which leads with pacing and defibrillating electrodes are implanted into both the right and left ventricles of a patient's heart to enable simultaneous pacing of...
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