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7435789 |
Crystalline high-compliance glycolide copolymers and applications thereof
The present invention is directed toward an absorbable crystalline segmented copolymer comprising a polyalkylene succinate segment end-grafted in a single-step with a mixture of monomers comprising...
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7424320 |
Tissue localizing and marking device and method of using same
A delivery apparatus for the percutaneous placement of a medical device at an area of interest in a tissue mass comprises an introducer comprising a cannula having an insertion tip, an expulsion...
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7378144 |
Oriented polymer implantable device and process for making same
A device is formed by the process into a bone screw or fastener, wherein the head has a degree of polymer alignment and strength, and wherein the shank has a higher degree of polymer alignment and...
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7329271 |
High strength suture with absorbable core
A novel high tensile strength semi-absorbable composite suture with minimized non-absorbable mass. The suture has a core made from a bioabsorbable polymer. The core is covered by a braided sheath....
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7321008 |
Bioabsorbable branched polymers end-capped with diketene acetals
Star polymers of soft segment forming monomers are useful in forming surgical devices. The star polymers can be endcapped with diketene acetals, mixed with a filler and/or cross-linked. The polymer...
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7192437 |
High strength fibers of l-lactide copolymers, ε-caprolactone, and trimethylene carbonate and absorbable medical constructs thereof
The present invention is directed to crystalline copolymers of l-lactide and a minor portion of a cyclic monomer, preferably ε-caprolactone or trimethylene carbonate or both. The present...
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7148315 |
Monomer addition techniques to control manufacturing of bioabsorbable copolymers
Monomer addition methodology is provided to adjust monomer addition rates to a polymerization reactor. Advantages of the invention include control of bioabsorbable copolymer structure, improvement...
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7144412 |
Gold suture and method of use in wound closure
A method of wound closure comprising providing a gold suture and closing the laceration with the gold suture. The laceration is closed by: inserting the suture into the dermis and through the...
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7141302 |
Suture material for surgery, processes for its production and the use thereof
A suture material for surgery comprises one or more filaments and is formed with a coating, which is characterized in that the coating at least partly comprises a bioresorbable polymer, which is...
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7129319 |
Amorphous polymeric polyaxial initiators and compliant crystalline copolymers therefrom
An absorbable crystalline, monocentric polyaxial copolymer comprising a central carbon or nitrogen atom and at least three axes, each of which includes an amorphous flexible component adjacent and...
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7070858 |
Amorphous polymeric polyaxial initiators and compliant crystalline copolymers therefrom
An absorbable crystalline, monocentric polyaxial copolymer comprising a central carbon or nitrogen atom and at least three axes, each of which includes an amorphous flexible component adjacent and...
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7070610 |
Monofilament suture and manufacturing method thereof
The present invention relates to a monofilament suture prepared by co-extruding polymers having different Young's moduli and to a process for preparing the same. The suture is prepared in such a...
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7048753 |
Coated, slow-absorbing textile constructs for sutures and tissue engineering
The present invention is directed to crystalline copolymers of l-lactide and a minor portion of a cyclic monomer, preferably ε-caprolactone or trimethylene carbonate or both. The present...
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7029490 |
High strength suture with coating and colored trace
A high strength abrasion resistant surgical suture material with improved tie down characteristics is color coded for visualization and identification purposes. The suture features a multifilament...
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7026437 |
Amorphous polymeric polyaxial initiators and compliant crystalline copolymers therefrom
An absorbable crystalline, monocentric polyaxial copolymer comprising a central carbon or nitrogen atom and at least three axes, each of which includes an amorphous flexible component adjacent and...
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7001410 |
Bioabsorbable sealant
Openings in a mammalian body made by any medical procedure or non-medical event are sealed with a bioabsorbable plug or sewn with a bioabsorbable suture. In one exemplary embodiment, the plug in...
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6994719 |
High strength suture with colored trace at one end
A high strength abrasion resistant surgical suture material with improved tie down characteristics is color coded for visualization and identification purposes. The suture features a multifilament...
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6977231 |
Suturable adhesion-preventing membrane
A suturable adhesion-preventing membrane has high suture strength, good biocompatibility, decomposition and absorption in a living body, sufficient adhesion-preventing effect, and desirable guided...
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6945985 |
Method for making fast absorbing sutures by hydrolysis
A method for making a surgical article is provided which comprises exposing a bioabsorbable material, e.g., a copolymer derived from a major amount of glycolide and a minor amount of lactide, to a...
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6881766 |
Sutures and coatings made from therapeutic absorbable glass
Sutures fabricated from and/or coated with compositions including water-soluble glass are described herein. Pledgets containing water-soluble glass within the interstices of the pledget and/or...
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6878757 |
Antimicrobial suture coating
Compositions with antimicrobial properties contain a fatty acid ester salt mixed with a bioabsorbable copolymer. These compositions are useful in forming coatings for surgical articles, including...
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6794484 |
Crystallizable polylactone copolymers prepared from mono- and di-functional polymerization initiators
The present invention is directed to absorbable polylactone copolymers prepared in part from about 2 to about 80 mole percent glycolide, utilizing a combination of a monofunctional polymerization...
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6747121 |
Poly(L-lactide-co-glycolide) copolymers, methods for making and using same, and devices containing same
The present invention relates in general to implantable, resorbable copolymers containing L-lactide and glycolide repeat units, and in particular to terpolymers containing L-lactide, glycolide, and...
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6743505 |
Bioabsorbable multifilament yarn and methods of manufacture
The present invention relates to a process of forming bioabsorbable, multifilament yarn from Lactide-rich copolymers, including the steps of extruding and spinning a Lactide-rich copolymer to form...
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6712838 |
Braided suture with improved knot strength and process to produce same
The present invention discloses a process for producing a braided suture having an improved knot strength comprising heating a braided suture coated with a low molecular weight biocompatible...
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6706058 |
Resorbable, synthetic, medical coating material, method for its manufacture and its use in medicine
The invention relates to a coating material for medical treatment, particularly a wound contact material, of resorbable, synthetic material, which is formed from a terpolymer based on lactide,...
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6703035 |
Absorbable &egr -caprolactone copolymers
This invention deals with crystalline, nitrogen copolyester lubricant coating devices comprising sutures, wherein said lubricant comprises a triaxial copolyester chain with a central nitrogenous...
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6689153 |
Methods and apparatus for a coated anchoring device and/or suture
A coated/impregnated anchoring device and/or suture to prevent infection, deliver site specific drugs, and deliver human growth factors to the surgical site. The coatings can include anti-microbial...
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6624097 |
Implantable fibers and medical articles
An implantable medical article as well as an implantable fiber which is particularly useful for medical implants is disclosed. The fiber includes comprises a first component formed from a...
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6616687 |
Surgical suture
The present invention relates to a coating material for surgical sutures which comprises as essential ingredients a copolymer having repeating units of lactic acid and ε-caprolacton and calcium...
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6607548 |
Resorbable polymer compositions
A novel polymer composition is provided which includes a base material including a biodegradable polymer or copolymer, and a copolymer additive including one or more monomers imparting a tensile...
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6605294 |
Methods of using in situ hydration of hydrogel articles for sealing or augmentation of tissue or vessels
Pharmaceutically acceptable hydrogel polymers of natural, recombinant or synthetic origin, or hybrids thereof, are introduced in a dry, less hydrated, or substantially deswollen state and rehydrate...
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6503991 |
Copolyesters with minimized hydrolytic instability and crystalline absorbable copolymers thereof
The present invention is directed to crystalline, absorbable block/segmented copolymers which are the reaction product of a linear prepolymer which is a polytrimethylene dicarboxylate of succinic,...
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6498229 |
Direct synthesis of segmented glycolide copolymers and crystalline materials therefrom
The present invention is directed to a method for the direct, one-step synthesis of crystalline segmented glycolide copolymers having less than 80 percent glycolide-based sequences in the...
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6494898 |
Absorbable copolymers and surgical articles fabricated therefrom
A synthetic absorbable monofilament comprising glycolide and epsilon caprolactone is provided. The monofilament exhibits physical characteristics equivalent to or superior than gut sutures. The...
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6335383 |
Microdispersions for coating surgical devices
The present invention provides surgical article and suture coated with bioabsorbable microdispersions which contains a fluid carrier that is a liquid polymer and a particular material.
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6332884 |
Two phase thermally deformable biocompatible absorbable polymer matrix for use in medical devices
An absorbable biocompatible polymeric matrix is described. The matrix has a continuous phase that is preferably amorphous. The matrix also has a disperse phase of low melting biocompatible material...
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6315788 |
Composite materials and surgical articles made therefrom
Composite materials have a core portion formed from a polyalkylene oxide initiated block copolymer having one of the blocks made from hard phase forming monomers and another of the blocks made from...
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6277927 |
Absorbable block copolymers and surgical articles fabricated therefrom
Block copolymers wherein the first block contains from about 20 to about 80 mole percent of repeating units derived from lactide randomly combined with from about 20 to 80 mole percent of repeating...
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6270517 |
Suture assembly and method
A suture assembly made of bioabsorbable material is disclosed having a central body member with a plurality of elongated lateral members extending therefrom, each lateral member having body tissue...
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6264674 |
Process for hot stretching braided ligatures
The present invention provides an apparatus and process for improving the properties of braided ligature by hot stretching the braid.
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6235869 |
Absorbable polymers and surgical articles fabricated therefrom
Synthetic absorbable medical devices made totally or in part from a random polymer comprising glycolide, lactide, trimethylene carbonate, and caprolactone are provided. The polymer can be...
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6206908 |
Absorbable polymer and surgical articles fabricated therefrom
Absorbable copolymers are fabricated from the random polymerization of 1,4 dioxane-2-one and 1,3 dioxane-2-one monomers. The copolymers are useful in forming surgical articles, including both...
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6203564 |
Braided polyester suture and implantable medical device
A braided polyester suture made from polyester yarn filaments having a tenacity of from about 7 to about 11 g/denier, a percent elongation to break of less than about 30 percent and the polymer...
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6197320 |
Absorbable E-caprolactone polymers and medical devices
Crystalline, low melting -Caprolactone polymers which undergo accelerated hydrolysis, and their use as lubricant coatings and/or as coatings containing bioactive agents, as carriers of viable...
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6183499 |
Surgical filament construction
We have discovered a surgical filament suitable for use as a suture or ligature that comprises a multifilament core having a plurality of filaments that are oriented having an external surface and...
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6177094 |
Bioabsorbable blends and coating composition containing same
A bioabsorbable blend is provided which comprises the reaction product of 1) a bioabsorbable copolymer obtained by polymerizing a major amount of epsilon-caprolactone and a minor amount of at least...
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6165202 |
Absorbable polymers and surgical articles fabricated therefrom
Synthetic absorbable medical devices made totally or in part from a random polymer comprising glycolide, lactde and caprolactone are provided. The polymer can be fabricated into a monofilament...
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6143863 |
Melt-stable lactide polymer composition and process for manufacture thereof
A lactide polymer composition combining compositional and purity limitations and catalyst optimization or addition of stabilizing agents resulting in a melt-stable polymer is disclosed. The...
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6130271 |
Deformable absorbable surgical device
A deformable surgical repair device is manufactured from a block or graft copolymer. The copolymer comprises a plurality of first linkages selected from the group consisting of glycolic acid ester...
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