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8142475 Adhesive suture structure and methods of using the same  
According to an aspect of the present disclosure, a surgical suture needle assembly is provided including an elongate tube defining a lumen through at least a portion of a length thereof; and a...
8092823 Osteogenic implants with combined implant materials and methods for same  
Described are osteogenic implants that include a first implant material covered at least in part by a second implant material carrying an osteogenic protein such as a bone morphogenic protein. The...
8080521 Flowable carrier matrix and methods for delivering to a patient  
A carrier matrix may be delivered to a target position within a patient in a minimally invasive manner by first cutting a collagen sponge sheet into a plurality of relatively small pieces. These...
7850985 Tissue augmentation devices and methods  
Tissue augmentation devices, as well as methods of manufacturing and using the same, are disclosed. In certain embodiments, a tissue augmentation device comprises an elongate tissue penetrating...
7850894 Tissue holding devices and methods for making the same  
Various methods are provided for forming tissue holding devices having predetermined shapes suitable for use in surgical applications, and devices formed in accordance with such methods are also...
7722895 Osteogenic implants with combined implant materials, and materials and methods for same  
Described are osteogenic implants that include a first implant material covered at least in part by a second implant material carrying an osteogenic protein such as a bone morphogenic protein. The...
7671014 Flowable carrier matrix and methods for delivering to a patient  
A carrier matrix may be delivered to a target position within a patient in a minimally invasive manner by first cutting a collagen sponge sheet into a plurality of relatively small pieces. These...
7626070 Reinforced closure anchor  
A reinforced closure anchor includes a fabric layer having an adhesive side, an opposite non-adhesive side, and an outer edge. An anchor member layer having a reinforcing structure, an adhesive...
7001410 Bioabsorbable sealant  
Openings in a mammalian body made by any medical procedure or non-medical event are sealed with a bioabsorbable plug or sewn with a bioabsorbable suture. In one exemplary embodiment, the plug in...
6977231 Suturable adhesion-preventing membrane  
A suturable adhesion-preventing membrane has high suture strength, good biocompatibility, decomposition and absorption in a living body, sufficient adhesion-preventing effect, and desirable guided...
6773699 Light energized tissue adhesive conformal patch  
Consistent with the present invention, tissue adhesive compositions and an associated laser exposure system are provided for bonding or sealing biological tissues. The compositions are comprised of...
6183499 Surgical filament construction  
We have discovered a surgical filament suitable for use as a suture or ligature that comprises a multifilament core having a plurality of filaments that are oriented having an external surface and...
5954748 Gelatin coated gut suture  
A catgut suture includes a cross linked gelatin coating which is substantially insoluble in tubing or storage solution. The gelatin coating is formed by immersing the gut suture in aqueous gelatin...
5931165 Films having improved characteristics and methods for their preparation and use  
Gelatin film compositions are useful for immobilization over tissue, usually by the application of energy to the films. Exemplary films comprise cross-linked and non-cross-linked granular and...
5925065 Coated gut suture  
A coated gut suture is prepared by applying a moisture-retaining substance to the gut suture, followed by coating the suture with a synthetic bioabsorbable polymer. A particularly useful...
5919473 Methods and devices for delivering opioid analgesics to wounds via a subdermal implant  
An analgesic agent delivery system and method of treating postoperative pain comprising an analgesic agent such as morphine and an extended-release drug delivery device. The device may be placed in...
5891167 Collagen coated gut suture  
A catgut suture includes a dehydrothermal cross-linked collagen coating which is insoluble in tubing solution. The collagen coating is formed by immersing the gut suture in a solution of collagen...
5725522 Laser suturing of biological materials  
Methods and systems for endoscopic suturing of biological tissue are disclosed. Endoscopic instruments are described which serve to position a suture material at an anastomotic site and deliver...
5690675 Methods for sealing of staples and other fasteners in tissue  
Wounds in lung tissue are closed in a two step method consisting essentially of applying fasteners to a region adjacent to the wound, wherein the fasteners may cause penetrations. The fasteners are...
5618312 Medical materials and manufacturing methods thereof  
Disclosed are a medical material and a production process thereof. The medical material has a membrane configuration and is produced by impregnating a membranous material with collagen or gelatin...
5614587 Collagen-based bioadhesive compositions  
Collagen-based compositions useful in the attachment of tissues, or the attachment of tissues to synthetic implant materials, are disclosed. The compositions comprise collagen crosslinked using a...
5584857 Suture coating and tubing fluid  
A coating and tubing fluid for sutures, especially gut sutures, is provided. The coating composition includes linseed oil, an organic solvent and a catalyst. The tubing fluid includes water, a...
5514181 Absorbable structures for ligament and tendon repair  
A fully absorbable prosthesis (1) for the repair of damaged ligaments and/or tendons in the form of a multilayer spiral roll comprising the following spiral layers: a foraminous layer (2) of a...
5431639 Treating wounds caused by medical procedures  
Incised or injured tissue is treated by introducing material that encourages healing to desired depths within the tissue. Particularly, the invention provides treatment of an access channel to a...
5211644 Process and apparatus for a dermal graft  
The process and apparatus for an autologous dermal graft transfer provides for the easy and accurate placement of dermal grafts during plastic surgery, typically for the filling of wrinkles or scars.
4511653 Process for the industrial preparation of collagenous materials from human placental tissues, human collagenous materials obtained and their application as biomaterials  
This process of preparation consists in subjecting said placental tissue after pressing, grinding and washing in a neutral and acid medium to a treatment in alkaline medium at a temperature less...
4451397 Method of preparing collagen products  
New and highly stable preparations containing collagen in association with mucopolysaccharides are obtained by combining a homogeneous gel or solution of crosslinked or decrosslinked collagen, and...
4433688 Method of coating a catgut suture  
Catgut suturing filament protected by a flexible polymer sheath that is slowly hydrolytically degradable and impervious to body fluid degratative enzymes. The sheath is prepared by coating the...
4394370 Bone graft material for osseous defects and method of making same  
Complexes of reconstituted collagen and demineralized bone particles or reconstituted collagen and a solubilized bone morphogenetic protein fabricated in a sponge suitable for in vivo implantation...
4378017 Composite material of de-N-acetylated chitin and fibrous collagen  
A composite material of de-N-acetylated chitin and fibrous collagen, which may be prepared by bringing the de-N-acetylated chitin and the fibrous collagen into mutual contact in an aqueous acidic...
4350629 Procedures for preparing composite materials from collagen and glycosaminoglycan  
This invention relates to crosslinked collagen and glycosaminoglycan materials, and to procedures for preparing such materials. It has been discovered that if collagen fibrils in an aqueous acidic...
4347234 Medicinally useful, shaped mass of collagen resorbable in the body  
A shaped mass resorbable in the body, comprises collagen and a bioresorbable binding agent for collagen, the binding agent being selected, e.g., from polymers of C2-16 α-hydroxyalkanoic acids, ...
4280954 Crosslinked collagen-mucopolysaccharide composite materials  
Composite materials are disclosed which are formed by contacting collagen with a mucopolysaccharide and subsequently covalently crosslinking the resultant polymer. These composite materials have a...
4115928 Freeze-dry process and product  
An improvement in freeze-drying of skin tissue for use in treating wounds and diseased areas of the body wherein un-frozen skin is partially dried and frozen by drawing a vacuum across the skin...
4034750 Electrochemically linking collagen fibrils to animal tissue  
Skin-like collagen membranes are adapted for protecting a wound, lesion or the like on animal bodies. These collagen membranes are semipermeable and are electrochemically-linked to the damaged...
4021522 Method of forming collagen dispersions  
A method of preparing collagen fibre dispersions comprising treating a collagenous material such as hide corium with a solution containing an alkaline earth metal hydroxide and an alkaline earth...
4016877 Fibrous collagen derived web having hemostatic and wound sealing properties  
Non-woven, liquid-laid, fibrous web having hemostatic and adhesive properties adapted to seal a wound formed of fibers consisting of an ionizable, water-insoluble, partial salt of collagen, the web...
3988782 Non-antigenic, non-thrombogenic infection-resistant grafts from umbilical cord vessels and process for preparing and using same  
Arteries and veins of umbilical cords are hardened and shaped by processes described. Prostheses in the form of tubes, patches and conduits are prepared from the shaped vessels. The prostheses are...
3949755 Surgical ligature  
A surgical ligature in which a sterile thread has a surface on which is a succession of areas, for example, lines or dots, of contrasting shades, whereby at least one of the shades appears dark...
3918455 Combined surgical suture and needle  
A combination suture-needle assembly wherein the suture diameter and the maximum needle diameter are preferably the same or the suture diameter may be less than the needle diameter. The needle is...
3896814 Collagen based threads  
A new type of thread comprising collagen or catgut, remaining supple in dry condition is described. The thread is treated with water and with one or more products capable of maintaining moisture on...
3896813 Sutures having long-lasting biocidal properties  
Sutures are provided with long-lasting biocidal properties against both gram-negative and gram-positive bacteria by incorporating substantially water-insoluble salts of an acid antibiotic and a...
3894132 Method of forming collagen dispersions  
A method of preparing collagen fibre dispersions comprising softening the collagen in an alkali hydroxide solution, coarsely dicing or mincing the collagen and mashing or extruding the diced or...
3810473 LIQUID-LAID, NON-WOVEN, FIBROUS COLLAGEN DERIVED SURGICAL WEB HAVING HEMOSTATIC AND WOUND SEALING PROPERTIES  
Liquid-laid, non-woven, fibrous web having hemostatic and adhesive properties sufficient to seal a wound formed of fibers of ionizable, water-insoluble, partial acid salts of collagen, the web...
3799169 LATERAL RELEASE SUTURE  
A surgical needle is manufactured with an open channel at the blunt end thereof sized to receive a suture. The suture is bonded to the channel with an adhesive that prevents "pull-out" of the...
3791388 COVERED SUTURE  
Surgical sutures having an improved knot strength are constructed with a central core of multifilament yarn that has been impregnated with an adhesive binder. The adhesive binder coated core yarn...
3729007 RESORBABLE SURGICAL SUTURE  
A resorbable catgut surgical suture impregnated with a liquid silicone, such as dimethylpolysiloxane.
3649163 METHOD FOR REMOVING NONCOLLAGENOUS MATTER FROM MAMMALIAN GUT  
Gut strands used to manufacture sutures, tennis racquet stringing and such are treated at least once with an aqueous nonionic surfactant solution consisting essentially of from about 0.2 to about 5...
3625811 METHOD OF PREPARING YARN AND THE LIKE FROM ANIMAL HIDE  
Collagen fiber is obtained from limed animal hide by a process which involves reliming, treating with an enzyme, and finally, beating to loosen the fiber structure of the hide. The fiber structure...
3551560 PROCESS OF RECONSTRUCTING TENDONS,CARTILAGE,NERVE SHEATHS,AND PRODUCTS  
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