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7588565 |
Method and device for anastomoses
Provided herein is a device for use in an anastomosis of tissue(s) comprising a biocompatible material and a means of applying radiofrequency energy or electrical energy to generate heat within...
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7553319 |
Auto-injector apparatus and methods for sealing a vascular puncture
Apparatus for sealing a puncture communicating with a blood vessel includes a pair of syringe barrels having sealing components therein, and a plunger assembly biased to slide within the barrels...
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7482504 |
Dressing for treatment of short wounds located in high tension areas
A dressing and method for treating high-tension wounds. First and second layers of a 1-butyl cyanoacrylate 16 adhesive are applied to a short, high-tension wound, with the first and second layers...
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7431729 |
Patent foramen ovale (PFO) closure device with radial and circumferential support
The present invention provides a device for occluding an anatomical aperture, such as a septal defect or patent foramen ovale (PFO). The occluder includes two sides connected by an intermediate...
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7351249 |
Systems, methods, and compositions for achieving closure of suture sites
Systems and methods employ functional instruments to close incisions and wounds using a suture knot in combination with a biocompatible material composition. The systems and methods are well suited...
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7316705 |
Adhesive including medicament and device and method for applying same
The present invention provides a device and method for safely applying cyanoacrylate or other adhesives to skin lacerations.
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7279001 |
Systems, methods, and compositions for achieving closure of vascular puncture sites
Systems and methods convey a closure material into a catheter, e.g., to seal a puncture site in a blood vessel. The closure material comprises a mixture of first and second components, which, upon...
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7267681 |
Wound closure system and method
Methods and systems for closing wounds using wound closures and a flowable adhesive skin paint are disclosed. The flowable adhesive does not adhere the wound closures to the skin over the wound to...
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7182744 |
Method and apparatus for aneurismal treatment
An irritant or polymer is dispensed to the inner surface area of an aneurysm to exert a contractile force on the inner surface area of the aneurysm, thereby shrinking the aneurysm. As a result, the...
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7105011 |
Method for achieving tissue changes in bone or bone-derived tissue
A method of achieving tissue changes in bone or bone-derived organic tissue, in which method bone or bone-derived organic tissue is provided, an interfacing agent is applied to the bone or...
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7081103 |
Direct dual filling device for sealing agents
A filling device for connecting a dispensing instrument having multiple fluid reservoirs to multiple containers is disclosed. More particularly, the present invention discloses a connecting device...
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7044982 |
Surgical repair of tissue defects
A method for repairing a defect in living mammalian tissue comprising: covering a tissue defect and surrounding tissue with a prosthetic by placing the prosthetic over the defect and against the...
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7044916 |
Technique to confirm correct positioning of arterial wall sealing device
Methods and systems related to sealing punctures in blood vessels (such as following an angio or PTCA procedure) are disclosed. The position of a distal end of an introducer assembly in tissue is...
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6989022 |
Clotting cascade initiating apparatus and methods of use and methods of closing wounds
Wound closure methods and apparatus are provided which utilize blood fluid by activating the clotting cascade of the blood fluid outside the body within a substantially enclosed sterile container...
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6955682 |
Wound closure system and methods
A wound closure system and methods utilizes a patient's own blood. The system preferably includes a chamber with a needle and a plunger for transferring and storing blood prior to surgery and the...
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6939364 |
Composite tissue adhesive
Consistent with the present invention, tissue adhesive compositions and an associated laser exposure system are provided for bonding or sealing biological tissues. The compositions are comprised of...
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6932833 |
Method and barrier for limiting fluid movement through a tissue rent
A method and device provides for limiting fluid movement through a rent in a membranous tissue by forming a biocompatible and biodegradable barrier at the site of the rent. The barrier is formed by...
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6921380 |
Component mixing catheter
A multi-component sealant applicator comprises a dual catheter for delivering sealant. Each catheter communicates with one of a pair of fluid sealant agent sources and comprises a mixing volume...
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6894140 |
Fast curing compositions
Fast curing surgical adhesives and sealants contain an NCO-terminated hydrophilic urethane prepolymer derived from an aromatic diisocyanate and a polyol. Substantially all the aromatic diisocyanate...
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6849082 |
Method for curing cyanoacrylate adhesives
A new adhesive method using an adhesive composition including cyanoacrylate adhesive and a stabilizing agent to join together portions of a substrate, particularly useful in suturing and similar...
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6783539 |
Phototriggerable, collagen-crosslinking compounds for wound closure
A phototriggerable composition and method for use in crosslinking protein such as collagen comprising application of a tethered diazopyruvate composition followed by irradiation, whereby the...
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6743248 |
Pretreatment method for enhancing tissue adhesion
A closure device is provided for sealing a puncture in a body vessel. The closure device includes an energy delivery device for delivering energy to tissue adjacent the vessel puncture which...
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6733515 |
Universal introducer
A device for introducing a catheter into a vessel through a puncture in a vessel and for sealing the puncture. The device includes an elongated body having a proximal end and a distal end sized to...
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6723114 |
Polyester/cyanoacrylate tissue adhesive formulations
The present invention is directed to bioabsorbable adhesive/hemostatic formulations of a 2-alkoxyalkylcyanoacrylate and liquid or solid polymeric modifiers and adjuvant. The present adhesive...
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6702760 |
Biopsy and coagulant device
The biopsy device has a biopsy channel connected to an aspiration and collecting chamber and at least one application channel connected to a dispensing chamber integrally connected with the...
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6699484 |
Fibrin sealants or adhesives comprising a hyaluronic acid derivative material
An especially useful fibrin glue composition comprises a biocompatible, bioabsorbable hyaluronic acid derivative material, upon which are applied or chemically bonded fibrinogen and thrombin, along...
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6699262 |
Percutaneous tissue track closure assembly and method
A percutaneous tissue track closure assembly ( 2 ) includes a semipermeable barrier ( 26 ) mounted to the distal end of a tubular barrier carrier ( 20 ). The barrier is passed down a tissue track (...
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6673093 |
Methods and apparatus for in situ formation of hydrogels
Methods and apparatus of forming in situ tissue adherent barriers are provided using a sprayer capable of applying two or more viscous crosslinkable components to tissue. The sprayer comprises...
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6669713 |
Implantable tissue fastener and system for treating gastroesophageal reflux disease
A system including an implantable fastener for fastening layers of tissue is disclosed. In one embodiment, the fastener includes a proximal anchor member and a distal anchor member each being...
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6652559 |
Wound closure system
A wound closure system ( 10 ) for closing a wound on a patient comprises an elongated flexible backing strip ( 12 ) having a length and width sufficient to secure facing edges of the wound in close...
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6622731 |
Bone-treatment instrument and method
Ablation devices and associated methods are provided for use in palliative treatment of a bone tumor on or in a compact bone region. The bone treatment devices include an elongate probe having a...
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6613020 |
Method of applying a mixture of two liquid components as well as a device for carrying out the method
A novel device and method for applying two or more liquid components, for example fibrin sealant-forming components, comprises sources of the components fliud communication with, but remote from,...
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6610078 |
Suture material for wounds based on methylidene malonate
A method for the suture of wounds, includes applying a sufficient quantity of a biocompatible, bio-adhesive mixture with at least 50% by weight of a methylidene malonate-based composition...
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6592597 |
Adhesive for attaching buttress material to a surgical fastening device
A surgical stapling instrument for clamping and stapling tissue. The instrument has a handle and first and a second opposed tissue clamping members connected to the handle. The members are movable...
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6589269 |
Patch and glue delivery system for closing tissue openings during surgery
A patch applicator has an elongate body with an inner lumen and an outer lumen arranged concentrically. A patch is also provided. In operation, a source of vacuum draws a vacuum through the inner...
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6585773 |
Insertable stent and methods of making and using same
An insertable stent is provided for joining together and facilitating healing of adjacent tissues. Typically, the tissues are mammalian tissues. The insertable stent is made from completely...
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6583117 |
Method of tissue repair
A method for joining tissue comprising aligning and abutting edges of the tissue to be joined applying a biodegradable, biological solder or an analogue thereof, across the edges and exposing the...
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6569185 |
Continuous infusion technique for arterial sealing
A method of performing a vascular closure whereby closure material is safely injected into the blood vessel and into the vascular opening.
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6547794 |
Method for fusing bone during endoscopy procedures
A method of fusing or welding bone in vivo and in a fluid medium, comprising: harvesting a piece of autologous implant bone; treating the implant bone and/or a receiving bone to expose organic...
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6524327 |
In-situ bonds
The invention relates to an organic hydrogel bond for living tissue. The bond is comprised of living tissue pre-treated with hydrogen peroxide, body derived fluids, including at least one...
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6482179 |
Apparatuses, methods and compositions for closing tissue puncture openings
Medical devices, and more particularly, devices, methods and compositions for sealing tissue puncture openings of patients after surgical operations are provided. A puncture wound sealing apparatus...
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6479725 |
Method of treatment of a wound or incision
A method for forming an incision or wound dressing. First, second, and third layers 2-octyl cyanoacrylate adhesive 18, 20 , and 22 are applied to a wound or incision site 14 , with each layer...
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6475182 |
Fluidic media introduction apparatus
A fluidic media introduction apparatus for closing an opening in a vessel wall includes an elongated member with a fluidic media introduction port and a guide wire lumen. The guide wire lumen...
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6458147 |
Compositions, systems, and methods for arresting or controlling bleeding or fluid leakage in body tissue
A biocompatible and biodegradable hydrogel compound, which is free of a hemostatic agent, is applied to arrest the flow of blood or fluid from body tissue. The compound preferably includes a...
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6454787 |
Collagen hemostatic foam
A hemostatic device formed of collagen particles and methods for producing and using the hemostatic device to control bleeding are provided. The collagen particles of the hemostatic device have a...
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6454786 |
Devices and methods for applying a mixture of two or more liquid components to form a biomaterial
Novel methods and devices which provide enhanced mixing and application of two liquid components to form a biomaterial with minimized aerosols is achieved using air flow rates below about 1.25...
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6428561 |
Biocompatible glue
Use of one or more saccharides, for example one or more non-toxic mono-, di-, tri-, oligo- or polysaccharides, in the manufacture of a biocompatible glue for adhering a first structure to a surface...
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6391049 |
Solid biodegradable device for use in tissue repair
A composition and method for a light activated composition for improved wound closure, is disclosed. The composition includes a biodegradable polymer that is impregnated with a solder that is...
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6371975 |
Compositions, systems, and methods for creating in situ, chemically cross-linked, mechanical barriers
A biocompatible and biodegradable barrier material is applied to a tissue region, e.g., to seal a vascular puncture site. The barrier material comprises a compound, which is chemically cross-linked...
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6361551 |
Collagen hemostatic fibers
A collagen fiber and methods for producing and using the collagen fiber of the inventions to prepare hemostatic fabrics to control bleeding are provided. The collagen particles (e.g., fibrils) of...
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