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Document Title |
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7384418 |
Methods and devices for delivery of agents to breast milk ducts
The invention provides devices, kits and methods for delivering an agent to a breast milk duct. Intraductal agent delivery provides an opportunity to treat a breast condition locally and avoid the...
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7371229 |
Dual electrode advanced electrochemical delivery system
The present invention is disclosed herein as an electrochemical cell having a cell housing with a first half cell and a second half cell, and an ion selective membrane between the cells. The...
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7338464 |
Non-constant pressure infusion pump
The present invention relates to an implantable infusion pump having a refillable infusate reservoir in fluid communication with a delivery site via a flow path. This flow path includes a flow...
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7335193 |
Osmotically-driven fluid dispenser
Improvements in a mini-osmotic pump and coating compositions are described. The dispensing pump includes an inner fluid-filled bag encased by an osmotic layer and outer, semi-permeable membrane....
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7316680 |
Osmotic delivery device having a two-way valve and a dynamically self-adjusting flow channel
An implantable osmotically driven delivery system having a dynamic, two-way valve and a self-adjusting, variable geometry fluid flow channel. As pressure within the agent delivery system increases,...
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7303674 |
Forward osmosis pressurized device and process for generating potable water
There is disclosed a process and device for Forward Osmosis (FO) Pressurized Device (FOPD) in general and one hydraulically coupled to a reverse osmosis (RO device for a FOPRO (Forward Osmosis...
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7250043 |
Catheter for modification of agent formulation
The present invention provides a catheter for use in delivering formulation that allows modification of the formulation prior to or concomitant with its transport or at a delivery site. The...
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7241457 |
Osmotically driven active agent delivery device providing an ascending release profile
In one aspect, the present invention is directed to an osmotic pump that automatically provides an ascending release rate of active agent as the osmotic pump functions in an environment of...
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7235068 |
Osmotic delivery system having space-efficient piston
An osmotic delivery system having a space-efficient piston is provided. The enclosure has an interior holding the piston, a protein or peptide, and an osmotic agent. The piston is movable with...
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7211076 |
Medical device for fluid delivery having low fluid flow rate
A device for delivering a drug includes a body having a proximal end and a distal end and an opening in the distal end thereof. An orifice mechanism at the distal end of the body communicates with...
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7207982 |
Osmotic pump with means for dissipating internal pressure
The present invention includes an osmotic pump that includes a means for venting an osmotic composition included in the pump before the internal pressure of the pump has the opportunity to build to...
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7112335 |
Minimally compliant, volume-efficient piston for osmotic drug delivery systems
An osmotic pump having a minimally compliant, volume-efficient piston positioned within a capsule is provided. The capsule has an interior surface, a beneficial agent, and an osmotic agent. The...
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7090668 |
Time-released substance delivery device
An implantable, time-released substance delivery device includes a casing having an exterior surface, and a number of pores disposed on the exterior surface of the casing. The time-released...
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7087035 |
Device and method for enhancing skin piercing by microprotrusions
A device and method for enhancing skin piercing by microprotrusions involves pre-stretching the skin to enhance pathway formation when the microprotrusions are pressed into the skin. An expandable...
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6979315 |
Passive flow control devices for implantable pumps
An implantable drug delivery device is provided with a passive flow control device is provided in the form of a valve which may assume two flow states. Flow control is achieved by duty cycling the...
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6976981 |
Osmotic delivery system with membrane plug retention mechanism
An osmotic delivery system has a membrane plug retention mechanism which can also be used to control the delivery rate of a beneficial agent from the osmotic delivery system. The osmotic delivery...
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6939556 |
Minimally compliant, volume efficient piston for osmotic drug delivery systems
An osmotic pump having a minimally compliant, volume-efficient piston positioned within a capsule is provided. The capsule has an interior surface, a beneficial agent, and an osmotic agent. The...
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6923800 |
Osmotic delivery system, osmotic delivery system semipermeable body assembly, and method for controlling delivery rate of beneficial agents from osmotic delivery systems
Osmotic delivery system semipermeable body assemblies that control the delivery rate of a beneficial agent from an osmotic delivery system incorporating one of the semipermeable body assemblies are...
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6918901 |
Device and method for enhancing transdermal agent flux
An agent delivery or sampling device ( 2 ) comprising a member ( 6 ) having a plurality of blades ( 4 ) for piercing the skin and a connecting medium ( 65 ) covering at least a part of the skin...
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6852104 |
Programmable insulin pump
An apparatus for delivering a bolus of a medical agent to a patient. The apparatus comprises a pump mechanism, a data input device, and a processor in data communication with the keypad and...
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6824538 |
System for preventing sudden cardiac death by nerve sprouting from right stellate ganglion
A system or apparatus is described for reducing the likelihood of the occurrence of ventricular arrhythmia in the heart of a patient having a myocardial infarction and an atrioventricular block,...
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6768425 |
Medical apparatus remote control and method
A system for providing medical treatment to a patient, including a medical treatment apparatus and a remote control device. The medical treatment apparatus has a local processor, and a local...
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6753328 |
Methods of inhibiting metastases
The invention relates to methods for preventing and treating disseminating cancers. Inhibition metastases of a primary tumor to a liver tissue is carried out by directly contacting a liver tissue...
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6740077 |
Implant with permeable element
An implant is suggested having a receptacle space for a therapeutic agent, which can leave the receptacle space through a permeable element. For exact dosage, an open-pore diffusion element is...
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6719751 |
Osmotic dosage form composed of an extruded polymer tube form
A dosage form manufactured from an extruded polymer tube and method for manufacturing the dosage form are disclosed. The dosage form is preferably an osmotic dosage form and includes a therapeutic...
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6689373 |
Devices and methods for pain management
The invention features devices and methods for the systemic delivery of fentanyl or a fentanyl congener (e.g., sufentanil) to treat pain. In the present invention, a drug formulation comprising...
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6682522 |
Valve for osmotic devices
An osmotic delivery system for controlled delivery of a beneficial agent includes an implant capsule having a beneficial agent reservoir, an osmotic agent which expands on contact with fluid...
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6666845 |
Implantable infusion pump
An implantable infusion pump to deliver stored infusate to a desired fluid delivery site. The pump includes a collapsible fluid chamber. The pump can include a multi-stage filtration system to...
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6652510 |
Implantable infusion device and reservoir for same
An implantable infusion device includes of a disc-shaped housing that is made from a biocompatible material and contains a reservoir. The reservoir defines a chamber that contains at least one...
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6643537 |
Programmable injector control
A fluid injection arrangement, particularly involving a systematic fluid injection programming capability, in the context of patient imaging systems, in which phases of contrast medium infection...
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6635268 |
Sustained delivery of an active agent using an implantable system
The invention is directed to a device for delivering an active agent formulation for a predetermined administration period. An impermeable reservoir is divided into a water-swellable agent chamber...
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6632217 |
Implantable osmotic pump
An implantable osmotic pump for delivering a pharmaceutical agent to a patient includes an osmotic engine, a substantially toroidal compartment disposed at least partially around the osmotic engine...
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6616652 |
Osmotic pump delivery system with pre-hydrated membrane(s) and/or primable catheter
An implantable osmotic pump system includes a pre-hydrated semipermeable membrane to reduce the time interval between implantation of the system into the patient and full operation of the pump...
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6599284 |
Osmotic device having a preformed passageway that increases in size
The present invention provides a simple and improved osmotic device ( 1 ) that is capable of providing a controlled release of active agent contained in the core ( 4 ) through a preformed...
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6582418 |
Drug pump with reinforcing grooves
A pump for pumping drugs, medicaments or other liquids is disclosed having suture loops co-extensive with the outside wall of the pump. At least one depression is formed in the outside wall of the...
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6569152 |
Sustained release delivery systems for solutes
The present invention relates to devices that allow for linear, sustained-release of solutes with adjustable initial-release kinetics. In particular, the present invention relates to devices for...
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6554822 |
Microbolus infusion pump
An implantable microbolus infusion pump is disclosed which includes an elastically deformable reservoir, an electrically activated microvalve, and a remotely activated control system. The control...
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6544252 |
Osmotic delivery system having space efficient piston
An osmotic delivery system having a space efficient piston. The capsule has an interior holding the piston, a beneficial agent, and an osmotic agent. The piston is movable with respect to an...
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6541021 |
Devices and methods for pain management
The invention features devices and methods for the systemic delivery of fentanyl or a fentanyl congener (e.g., sufentanil) to treat pain. In the present invention, a drug formulation comprising...
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6514689 |
Hydrogel biosensor
A biosensor ( 10 ) has a hydrogel ( 30 ) in a rigid and preferably biocompatible enclosure ( 20 ). The hydrogel ( 30 ) includes an immobilized analyte binding molecule (ABM) and an immobilized...
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6511473 |
Implantable bioartificial active secretion system
An implantable bioartificial active secretion system for providing a physiological secretion such as insulin necessary for functionality of a physiologic activity such as glucose metabolism of a...
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6491684 |
Fluid delivery device having a water generating electrochemical/chemical pump and associated method
A fluid delivery device generally including: an electrochemical pump, wherein the electrochemical pump is capable of generating water; an electrochemical pump product chamber, wherein the...
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6475750 |
Glucose biosensor
A biosensor ( 10 ) has a hydrogel ( 30 ) in a rigid and referably biocompatible enclosure ( 20 ). The hydrogel ( 30 ) includes an immobilized glucose-binding molecule such as concanavalin A (Con A)...
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6471689 |
Implantable drug delivery catheter system with capillary interface
The present invention relates to a drug delivery device which is implantable within a mammal and adapted for long-term efficient drug delivery to surrounding tissue. The drug delivery device is...
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6471688 |
Osmotic pump drug delivery systems and methods
Implantable osmotic pump devices and systems include multiple osmotic pumps and/or semipermeable membranes to extend the useful life cycle and functionality of the drug delivery system. Use of an...
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6464688 |
Osmotic pump delivery system with flexible drug compartment
An implantable osmotic pump system includes a rigid pump housing defining an opening adapted to receive a catheter; one or more membrane assemblies fitted to the pump housing; an osmotic engine...
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6454759 |
Microfabricated injectable drug delivery system
A microfabricated, fully integrated drug delivery system capable of secreting controlled dosages of multiple drugs over long periods of time (up to a year). The device includes a long and narrow...
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6443942 |
Medication device with protein stabilizing surface coating
The present invention provides medical devices such as medication infusion pumps having internal surfaces that are treated to inhibit protein denaturation. In accordance with the invention,...
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6436091 |
Methods and implantable devices and systems for long term delivery of a pharmaceutical agent
Implantable devices and osmotic pump and catheter systems for delivering a pharmaceutical agent to a patient at selectable rates include an impermeable pump housing and a moveable partition...
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6283953 |
Osmotic drug delivery monitoring system and method
Performance of delivery systems for delivering beneficial agents to an animal are monitored to determine the delivery rate of the beneficial agent and the proper operation of the beneficial agent...
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