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8167836 |
Tissue expander configured for drug delivery
A device includes a tissue expanding portion and an enclosure positioned on a surface of the tissue expanding portion. The enclosure includes an enclosure wall and a drug formulation pocket defined...
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8158150 |
Two-piece, internal-channel osmotic delivery system flow modulator
An osmotic delivery system flow modulator includes an outer shell constructed and arranged for positioning in an opening, an inner core inserted in the outer shell, and a fluid channel having a...
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8158002 |
Responsive gels and methods of use thereof
The present invention provides variable pore size filters. The variable pore size filters of the present invention comprise a fabric matrix, having a set pore size, wherein the fabric matrix is...
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8109923 |
Osmotic pump with remotely controlled osmotic pressure generation
Embodiments of a system including a remotely controlled osmotic pump device and associated controller are described. Methods of use and control of the device are also disclosed. According to some...
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8109922 |
Orifice device having multiple channels and multiple layers for drug delivery
An orifice device for delivering one or more drugs includes an inner member having a proximal end and a distal end; and a plurality of windings helically wound around the inner member. Each winding...
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8105307 |
Determining an injection region in a heterogeneous body structure
A device and method for determining at least one infusion and/or injection region for infusing and/or injecting a medical drug into a heterogeneous body structure in order to achieve a distribution...
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8052996 |
Two-piece, internal-channel osmotic delivery system flow modulator
An osmotic delivery system flow modulator includes an outer shell constructed and arranged for positioning in an opening, an inner core inserted in the outer shell, and a fluid channel having a...
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7981106 |
Electronically-controlled device for release of drugs, proteins, and other organic or inorganic chemicals
A device for drug release including a drug reservoir including a gate, wherein opening of the gate releases a drug stored in the drug reservoir, an electronic command and control (C & C) unit in...
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7976535 |
Method for control of the volume flux of a liquid in an osmotic micropump and osmotic micropump
The invention refers to a method for control of a volume flow in an osmotic micropump and an osmotic micropump. According to the invention, the osmotically driven volume flow of the solvent through...
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7955305 |
Needle inserter and method for infusion device
An infusion media delivery device includes a housing having a base adapted to be secured to a user's skin. An infusion media reservoir is supported by the housing. A moveable hollow needle is...
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7914500 |
Container for storing a product to be injected, and an injection device for use with the container
A container for storing a product to be injected, e.g., a therapeutic or diagnostic liquid, wherein the container includes a container body and a piston body arranged in the container body in a...
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7896867 |
Fluid delivery device having an electrochemical pump with an ion-exchange membrane and associated method
The present invention is directed to an apparatus and method for controllably adjusting a fluid delivery device. The device includes an electrochemical pump capable of transporting a fluid. A...
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7896868 |
Method and system for control of osmotic pump device
Embodiments of a system including a remotely controlled osmotic pump device and associated controller are described. Methods of use and control of the device are also disclosed. According to some...
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7879027 |
Controlled release devices for fusion of osteal structures
A device includes a first reservoir configured to include a degradation agent, a first control element configured to provide access to the first reservoir, and an expandable component configured to...
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7879028 |
Osmotic delivery systems and piston assemblies for use therein
An osmotic delivery system is disclosed for delivering an active agent formulation to a fluid environment. The osmotic delivery system typically comprises a reservoir having a lumen that contains...
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7819858 |
Remote controlled in vivo reaction method
Embodiments of a system including a remotely controlled reaction device and associated controller are described. Methods of use and control of the device are also disclosed. According to various...
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7817030 |
Remote controller for in situ reaction device
Embodiments of a system including a remotely controlled reaction device and associated controller are described. Methods of use and control of the device are also disclosed. According to various...
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7803148 |
Flow-induced delivery from a drug mass
Drug solutions (or other combinations of vehicle with entrained drug) are prepared by removing drug from one or more masses of a solid form of the drug. The solid form of the drug may be sparingly...
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7794451 |
Implantable central venous injection port and external needle guide
An assembly for subcutaneous injections comprising an implantable injection port comprising a body with a plenum, an elastomeric self-sealing diaphragm sealed to the body or with a plenum, an...
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7771414 |
Controlled release devices for therapeutic treatments of spinal discs
A device includes a first reservoir configured to include a degrading agent, a first valve in fluid communication with the first reservoir, and a reservoir driver configured to manipulate the first...
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7758567 |
Medical device including processor running independent processes to cooperatively control therapy
A medical system comprising an implantable medical device and an external controller. The medical device includes a therapy administration subsystem, a telemetry subsystem, and a control subsystem...
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7744556 |
Delivery tube assembly for an applicator
A delivery tube assembly is provided, the delivery tube assembly including a delivery tube including a delivery tube attachment end, an open delivery tube second end opposite the delivery tube...
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7708873 |
Induced-charge electro-osmotic microfluidic devices
This invention provides devices and apparatuses comprising the same, for efficient pumping and/or mixing of relatively small volumes of fluid. Such devices utilize nonlinear electrokinetics as a...
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7699834 |
Method and system for control of osmotic pump device
Embodiments of a system including a remotely controlled osmotic pump device and associated controller are described. Methods of use and control of the device are also disclosed. According to some...
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7682356 |
Osmotic delivery systems and piston assemblies for use therein
An osmotic delivery system is disclosed for delivering an active agent formulation to a fluid environment. The osmotic delivery system typically comprises a reservoir having a lumen that contains...
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7678103 |
Orifice device for delivering drugs at low fluid flow rates
An orifice device for delivering a drug includes an inner member having a proximal end and a distal end. A winding is helically wound around the inner member. The winding and the inner member...
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7621907 |
Implantable drug delivery system
An implantable medicament delivery device includes a core body which further includes a single basin or multiple smaller basins for containing a drug or a medicament. Each basin is covered by a...
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7479135 |
Automatic conveyor driven by hydrogels, provided with an adjustable output characteristic for conveying a medium
A device for the dosed output of a substance, the device involving hydrogel-based osmotic drive, wherein output characteristics of the device, including a time profile, may be adjusted by a user....
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7470267 |
Fluid delivery device having an electrochemical pump with an anionic exchange membrane and associated method
A fluid delivery device, comprising an electrochemical pump, wherein the pump is capable of transporting water; a pump product chamber, wherein the pump product chamber is capable of retaining...
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7419484 |
Administering device with an osmotic drive
An administering device with an osmotic drive for administering an injectable product includes a housing with a first chamber containing a solvent, a second chamber containing a solution and a...
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7407500 |
Osmotic delivery system flow modulator apparatus and method
An osmotic delivery system flow modulator assembly, an osmotic delivery system with a flow modulator assembly, and a method of assembling an osmotic delivery system. The osmotic delivery system...
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7407499 |
Osmotic pump with self-retaining, fast-start membrane plug
An osmotic pump includes a capsule having at least one delivery port formed at a first end and a membrane plug retained in a second end of the capsule remote from the delivery port to provide a...
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7384418 |
Methods and devices for delivery of agents to breast milk ducts
The invention provides devices, kits and methods for delivering an agent to a breast milk duct. Intraductal agent delivery provides an opportunity to treat a breast condition locally and avoid the...
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7371229 |
Dual electrode advanced electrochemical delivery system
The present invention is disclosed herein as an electrochemical cell having a cell housing with a first half cell and a second half cell, and an ion selective membrane between the cells. The...
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7338464 |
Non-constant pressure infusion pump
The present invention relates to an implantable infusion pump having a refillable infusate reservoir in fluid communication with a delivery site via a flow path. This flow path includes a flow...
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7335193 |
Osmotically-driven fluid dispenser
Improvements in a mini-osmotic pump and coating compositions are described. The dispensing pump includes an inner fluid-filled bag encased by an osmotic layer and outer, semi-permeable membrane....
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7316680 |
Osmotic delivery device having a two-way valve and a dynamically self-adjusting flow channel
An implantable osmotically driven delivery system having a dynamic, two-way valve and a self-adjusting, variable geometry fluid flow channel. As pressure within the agent delivery system increases,...
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7303674 |
Forward osmosis pressurized device and process for generating potable water
There is disclosed a process and device for Forward Osmosis (FO) Pressurized Device (FOPD) in general and one hydraulically coupled to a reverse osmosis (RO device for a FOPRO (Forward Osmosis...
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7250043 |
Catheter for modification of agent formulation
The present invention provides a catheter for use in delivering formulation that allows modification of the formulation prior to or concomitant with its transport or at a delivery site. The...
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7241457 |
Osmotically driven active agent delivery device providing an ascending release profile
In one aspect, the present invention is directed to an osmotic pump that automatically provides an ascending release rate of active agent as the osmotic pump functions in an environment of...
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7235068 |
Osmotic delivery system having space-efficient piston
An osmotic delivery system having a space-efficient piston is provided. The enclosure has an interior holding the piston, a protein or peptide, and an osmotic agent. The piston is movable with...
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7211076 |
Medical device for fluid delivery having low fluid flow rate
A device for delivering a drug includes a body having a proximal end and a distal end and an opening in the distal end thereof. An orifice mechanism at the distal end of the body communicates with...
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7207982 |
Osmotic pump with means for dissipating internal pressure
The present invention includes an osmotic pump that includes a means for venting an osmotic composition included in the pump before the internal pressure of the pump has the opportunity to build to...
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7112335 |
Minimally compliant, volume-efficient piston for osmotic drug delivery systems
An osmotic pump having a minimally compliant, volume-efficient piston positioned within a capsule is provided. The capsule has an interior surface, a beneficial agent, and an osmotic agent. The...
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7090668 |
Time-released substance delivery device
An implantable, time-released substance delivery device includes a casing having an exterior surface, and a number of pores disposed on the exterior surface of the casing. The time-released...
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7087035 |
Device and method for enhancing skin piercing by microprotrusions
A device and method for enhancing skin piercing by microprotrusions involves pre-stretching the skin to enhance pathway formation when the microprotrusions are pressed into the skin. An expandable...
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7074762 |
Composition and method for improving function of embryonic kidney transplants
A method and composition for enhancing the development of metanephric tissue upon transplantation into an allogenic or xenogenic host are disclosed. Metanephric tissue is removed from an embryonic...
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6979315 |
Passive flow control devices for implantable pumps
An implantable drug delivery device is provided with a passive flow control device is provided in the form of a valve which may assume two flow states. Flow control is achieved by duty cycling the...
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6976981 |
Osmotic delivery system with membrane plug retention mechanism
An osmotic delivery system has a membrane plug retention mechanism which can also be used to control the delivery rate of a beneficial agent from the osmotic delivery system. The osmotic delivery...
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6923800 |
Osmotic delivery system, osmotic delivery system semipermeable body assembly, and method for controlling delivery rate of beneficial agents from osmotic delivery systems
Osmotic delivery system semipermeable body assemblies that control the delivery rate of a beneficial agent from an osmotic delivery system incorporating one of the semipermeable body assemblies are...
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