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5788979 |
Biodegradable coating with inhibitory properties for application to biocompatible materials
A method is disclosed for coating a biomaterial to be placed in contact with a patient's blood flow to inhibit blood coagulation from adhering to the biomaterial that would otherwise result from...
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5786216 |
Inner-supported, biocompatible cell capsules
A biocompatible capsule for containing cells for implantation is prepared containing an inner support that provides tensile strength to the capsule. The capsule may be a tubular semipermeable...
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5782798 |
Techniques for treating eating disorders by brain stimulation and drug infusion
Techniques using one or more drugs and/or electrical stimulation for treating an eating disorder by means of an implantable signal generator and electrode and/or an implantable pump and catheter. A...
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5783302 |
Thermoplastic elastomers
TPE's which comprise A blocks or B blocks or both A blocks and B blocks, which are crystalline and in which at least a part of the crystallinity result from the presence of crystallizable side...
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5780044 |
Liquid delivery compositions
Improved biocompatible liquid delivery compositions, which are useful for the formation of sustained release delivery systems for active agents, are provided. The compositions include liquid...
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5776184 |
Intravasoular stent and method
A device for delivery of a therapeutic substance into a body lumen including a polymer in intimate contact with a drug on a stent allows the drug to be retained on the stent during expansion of the...
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5770076 |
Micromachined capsules having porous membranes and bulk supports
Surface micromachining and bulk micromachining are employed for realizing a porous membrane with bulk support for a microparticle fiter. The filter is sufficiently sturdy to allow for easy...
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5762638 |
Anti-infective and anti-inflammatory releasing systems for medical devices
Medical devices for implantation into the body are coated with anti-infective and or anti-inflammatory agents. The medical devices can be, for example, endotracheal/tracheostomy tubes and...
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5755688 |
Alteration of nutritional product during enteral tube feeding
An apparatus and method are disclosed for modifying a liquid enteral nutritional product during delivery thereof from a supply to a feeding tube delivering the modified liquid enteral nutritional...
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5755689 |
Apparatus for adding marker dye to nutritional product during enteral tube feeding
An apparatus is useful for dye marking a liquid enteral nutritional product during delivery thereof from a supply container to a feeding tube delivering the nutritional product to the...
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5746715 |
Method of adding marker dye to nutritional product during enternal tube feeding
A method for dye marking a liquid enteral nutritional product during delivery thereof from a supply container to a feeding tube delivering the nutritional product to the gastrointestinal tract of a...
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5744151 |
Silver-based pharmaceutical compositions
The present invention relates to pharmaceutical compositions which are photostable and antimicrobially active comprising one or more medicinal agents and a stabilized ionized silver-based...
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5741243 |
Method of altering composition of nutritional product during enteral tube feeding
A method is disclosed for modifying a liquid enteral nutritional product during delivery thereof from a supply container to a feeding tube delivering the nutritional product to the gastrointestinal...
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5738651 |
Apparatus for altering composition of nutritional product during enteral tube feeding
An apparatus is disclosed for modifying a liquid enteral nutritional product during delivery thereof from a supply thereof, such as a hangable container, to a feeding tube delivering the liquid...
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5736160 |
Process and device for treating and healing a bone void
An improved method or process and device for treating and healing a bone void is disclosed, and in particular a method employing a surfactant for efficiently incorporating a biologically active...
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5731001 |
Locking couplings for osmotic delivery devices
A delivery system is disclosed for delivering a fluid-sensitive active agent such as a somatotropin, or an analogue or derivative thereof, to an animal such as a bovine. The delivery system...
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5728405 |
Method for preventing keratocyte loss
Keratocyte loss after trauma or injury to the corneal epithelium is prevented or reduced by applying to the corneal epithelium a keratocyte maintenance solution over a period of time sufficient to...
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5718694 |
Inhibition of adherence of microorganisms to biomaterial surfaces by treatment with carbohydrates
A method of inhibiting adherence of bacteria, fungus and other similar microorganisms to the surface of biomaterials is disclosed wherein biomaterials such as catheters and prosthetic devices are...
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5713852 |
Oral dosage and method for treating painful conditions of the oral cavity
A method is described for delivering a beneficial agent, such as an antiinflammatory agent, to the site of a painful condition in the oral cavity of a human being that utilizes an oral dosage form...
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5713888 |
Tissue implant systems
An implant assembly for a host tissue is provided. The implant assembly comprises a pouch including wall means defining a chamber for holding a second member, the wall means including an outer...
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5705191 |
Sustained delivery of active compounds from tubules, with rational control
The present invention is a method for releasing an active agent into a use nvironment, by disposing this active agent within the lumen of a population of tubules, and disposing the tubules into a...
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5693018 |
Subdermal delivery device
An apparatus for accurately infusing fluids into a patient at specific rates over an extended period of time. The apparatus is of a low profile, laminate or layered construction having a stored...
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5690682 |
Device and method for treatment of cardiac arrhythmia
An implantable programmable drug delivery system for injection of a pharmaceutical agent into the peritoneum to treat cardiac arrhythmia is described. The device consists of essentially three...
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5683424 |
Non-invasive monitoring and treatment of subjects in cardiac arrest using ECG parameters predictive of outcome
A method and apparatus for determining the metabolic state of the myocardium of a subject in ventricular fibrillation or asystole and/or for guiding therapeutic interventions. Electrocardiogram...
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5681278 |
Coronary vasculature treatment method
Method and apparatus for treating blood vessels in a mammal, particularly humans, especially coronary blood vessels, for vascular thrombosis and angioplasty restenosis, thereby to decrease...
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5674205 |
Device for treating gastrointestinal muscle disorders and other smooth muscle dysfunction
Direct injection of sphincteric botulinum toxin is disclosed as an effective, safe and simple method of treatment for disorders of gastrointestinal muscle or smooth muscles elsewhere in the body,...
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5660187 |
Process for preparing an intravaginal application system
In the process for preparing an intravaginal application system for the controlled release of substances, a milled sheet of silicone rubber containing the substances is inserted into one mold...
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5656032 |
Fluid delivery apparatus and method of making same
An apparatus for accurately infusing fluids into a patient at specific rates over an extended period of time and the method for making same. The apparatus includes one or more dispensers, of a low...
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5640954 |
Method and apparatus for continuously monitoring the concentration of a metabolyte
The present invention is directed to a method and an apparatus for continuously monitoring the concentration of a metabolite, such as glucose or lactic acid, in biological tissue, in which a...
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5632727 |
Biodegradable film dressing and method for its formation
The invention is directed to a biodegradable film dressing with or without additional therapeutic agents, an apparatus for spray delivery and a method for formation of the film dressing on a human...
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5630843 |
Double chamber tissue expander
A tissue expansion device for subcutaneous implantation in a patient consisting of an implantable expandable bladder prepared from a porous material which defines an infusion solution chamber, and...
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5618275 |
Ultrasonic method and apparatus for cosmetic and dermatological applications
Low frequency ultrasonic pressure waves of high intensity are applied to the skin to cause cavitation. A therapeutic agent may be applied to the skin in a predetermined amount prior to the...
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5613958 |
Transdermal delivery systems for the modulated administration of drugs
A transdermal delivery system for the modulated administration of drugs is described. The drug delivery device comprises a backing; a drug reservoir containing the drug, a plasticizer-type...
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RE35474 |
Transdermal drug delivery devices with amine-resistant silicone adhesives
This invention relates to an improved transdermal drug delivery device for the controlled transdermal delivery of amino-functional drugs. The improvement resides in providing the device with a...
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5595752 |
Increasing dressing percentage and carcass weight in finishing beef cattle
Beef cattle treated with bovine somatotropin and an estrogenic agent during the final stages of growth show improved carcass weight and dressing percent when the somatotropin is administered...
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5575815 |
Local polymeric gel therapy
A method for providing a synthetic barrier made of biocompatible polymeric materials in vivo which involves application of a material to a tissue or cellular surface such as the interior surface of...
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5569194 |
Device for permanent connection between an abdominal wall and an abdominal cavity
The invention relates to a structure for bringing about a permanent connection between the abdominal wall and the abdominal cavity of humans and animals. The structure is intended for the supply of...
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5569462 |
Methods for enhancing vascularization of implant devices
Methods for enhancing vascular support of cells housed within an implanted apparatus are disclosed. The methods comprise placing a population of therapeutic substance-producing cells into the cell...
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5567488 |
Multilayer barrier film for transdermal drug delivery system and ostomy applications
An oxygen and moisture impermeable multilayer barrier film is provided including a barrier layer comprising a homopolymer of vinylidene chloride or a copolymer of vinylidene chloride and vinyl...
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5567489 |
Multilayer halogen-free barrier film for ostomy and transdermal drug delivery applications
An oxygen and moisture impermeable multilayer barrier film which is free of halogens and which may be produced by coextrusion or lamination techniques is provided. The film provides excellent...
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5564439 |
Infusion device for soft tissue
An implant is provided with an open-celled silicone elastomer foam outer layer. The implant may be formed by compressively deforming beads mixed with liquid elastomer in a mold containing a...
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5562652 |
Antiseptic medical apparatus
A water activated antiseptic sheet including a base member having opposed surfaces and a reservoir located within the base member, the reservoir containing a water-activated antiseptic agent,...
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5562653 |
Medical devices composed of low ceiling temperature polymers
The present invention provides shaped medical devices adapted for implant and subsequent in-vivo disintegration within a human or animal body. In one embodiment, the medical device is fabricated...
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5562915 |
Sustained release capsule and formulations
A sustained release capsule adapted to be inserted into the rumen of a ruminant animal and means for retention of the capsule in the rumen. A sustained release capsule adapted to be inserted into...
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5562918 |
Drug dispensing system
A drug capsule comprises a sleeve forming a side wall of the capsule and having first and second end caps which close the opened ends of the sleeve. The end faces of the end caps are frangible so...
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5558664 |
Device for the dermal absorption of medicinal solutes
The device consists of: (a) an application reservoir or cell (1) whose base has a filling hole (4) for the solution and an opening that is fitted with a stopper (5) which presents micro-recesses on...
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5554148 |
Renewable neural implant device and method
Refillable immunoisolatory neurological therapy devices for local and controlled delivery of a biologically active factor to the brain of a patient. The devices include a cell chamber adapted for...
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5544651 |
Medical system and associated method for automatic treatment
A medical device comprises a sensor for at least periodically measuring a predetermined physiological parameter of a patient and for generating a signal encoding a measured value of the...
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5545139 |
Fluid container for use with a fluid delivery apparatus
A fluid container assembly which can be aseptically filled in the field with selected fluids and one which is specially designed for sterile coupling and use with fluid dispensing and delivery...
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5533971 |
Reduction of skin irritation during electrotransport
An electrotransport delivery device utilizing reservoir buffering at a select pH ranges in order to reduce skin irritation and skin resistance is provided. Cathodic reservoirs are buffered to a pH...
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