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7232435 Delivery of a sympatholytic cardiovascular agent to the central nervous system to counter heart failure and pathologies associated with heart failure  
A sympatholytic cardiovascular agent delivered by a drug delivery pump to a central nervous system site to alleviate symptoms and otherwise treat heart failure (HF) and pathologies associated with...
7226442 Microchip reservoir devices using wireless transmission of power and data  
Devices, systems, and methods are provided for wirelessly powering and/or communicating with microchip devices used for the controlled exposure and release of reservoir contents, such as drugs,...
7220245 Infusion apparatus  
A compact fluid dispenser for use in controllably dispensing fluid medicaments, such as, antibiotics, oncolytics, hormones, steroids, blood clotting agents, analgesics, and like medicinal agents...
7220244 Infusion apparatus with constant force spring energy source  
A fluid dispenser for use in controllably dispensing fluid medicaments, such as antibiotics, oncolytics, hormones, steroids, blood clotting agents, analgesics, bio pharmaceuticals and like...
7216665 Retractable reel  
A retractable reel includes a housing having a front cover and a rear cover, the rear cover including a first opening and the front cover including a second opening, a trough extending radially...
7214221 Multi-stage fluid delivery device and method  
A fluid delivery device for delivering a substance to a patient by way of infusion delivers the preparation at a rate of flow which varies in steps from a substantially constant higher rate, to a...
7211062 Solid solution perforator for drug delivery and other applications  
A solid drug perforator (SSP) system and an associated drug reservoir are provided for delivering theraputic, prophylactic and/or cosmetic compounds, for nutrient delivery and for drug targeting....
7201872 System and method for determining the presence of a substance in-vivo  
The present invention relates to a method and system for the in vivo determination of the presence and/or concentration of biological and/or chemical substances in body lumens. The system of the...
7198489 Use of ozone for the treatment of gum disease  
A method of treating gum disease, includes directing a stream of oxidizing gas onto a diseased gum for a period of time sufficient to kill microorganisms.
RE39533 Process for intra-uterine fertilization in mammals and device for implementation thereof  
The A fertilization process comprises includes the following steps: a) a container ( 15 ) which can be introduced into, and lodged in, the uterine cavity of the mammal is provided; b) the...
7169128 Multichannel fluid delivery device  
A compact fluid dispenser for use in controllably dispensing fluid medicaments, such as antibiotics, oncolytics, hormones, steroids, blood clotting agents, analgesics, and like medicinal agents...
7156838 Intradermal delivery device  
A delivery device for delivering a substance intradermally into the skin of a patient including a housing for contacting the surface of the skin and a disposable cartridge to be received in the...
7150741 Programmable dose control module  
The invention is directed to a dose control module for manipulating the dosage of one or more pharmaceutical solutions emanating from an implantable drug infusion pump. The dose control module has...
7144729 Methods and compositions for tissue regeneration  
The present invention provides the use and composition of matter of angiogenic or other growth/cytokine factors expressed by mixtures of allogeneic human cell strains or lines of various types and...
7122541 Methods of inhibiting metastases  
The invention relates to methods for preventing and treating disseminating cancers. Inhibition metastases of a primary tumor to a liver tissue is carried out by directly contacting a liver tissue...
7117041 System and method for programming a clinical device  
A care management system in which the management of the administration of care for patients is automated. Hospital information systems are monitored and the information from those systems is used...
7107106 System and method for collecting data and managing patient care  
A care management system in which the management of the administration of care for patients is automated. Hospital information systems are monitored and the information from those systems is used...
7103419 System and method for monitoring medication delivery to a patient  
A care management system in which the management of the administration of care for patients is automated. Hospital information systems are monitored and the information from those systems is used...
7096072 System and method for recording medication delivery to a patient  
A care management system in which the management of the administration of care for patients is automated. Hospital information systems are monitored and the information from those systems is used...
7094230 Systems and methods for delivering drugs to selected locations within the body  
An implantable reservoir device ( 400 ) including an enclosed membrane ( 408 ) on an expandable frame ( 402 ) that defines a reservoir ( 410 ) and includes a porous region ( 418 ). The reservoir...
7083068 Platen pump  
Disclosed is an infusion pump for expelling a fluid from a collapsible fluid reservoir to a patient. The pump includes a housing having a chamber therein for receiving the fluid reservoir. A first...
7070590 Microchip drug delivery devices  
Devices are provided for the controlled release of drug or other molecules. The devices include (1) a substrate, which optionally includes two or more substrate portions bonded together, (2) at...
7072725 Implantable therapeutic substance infusion device configuration system  
The present invention provides for a software-based computing environment that uses data communication systems or networks, including the Internet and World Wide Web technologies, to implement a...
7048729 Catheter and method of fluid removal from a body cavity  
A catheter comprises a catheter body having a wall defining a lumen therein and having plural holes defined through the wall in a pattern which prevents loculation, migration and blockage of a...
7008397 Cardiac implant and methods  
Cardiac implants include a conduit or scaffold having a first therapeutic agent in at least partial covering relation to at least a first portion of the scaffold, and a second therapeutic agent,...
7001371 Porous drug delivery system  
An implantable infection shield and system for drug delivery in vascular tissue includes a relatively non-biodegradable porous linked fibrous biomaterial which controls and directs cell growth and...
7001372 Apparatus and method for treating body tissues with electricity or medicaments  
A therapeutic device and therapeutic method for delivering electrical energy or a medicament to a body tissue or organ utilizing ultrasonic vibration to cause a device implanted in the body tissue...
6979315 Passive flow control devices for implantable pumps  
An implantable drug delivery device is provided with a passive flow control device is provided in the form of a valve which may assume two flow states. Flow control is achieved by duty cycling the...
6976981 Osmotic delivery system with membrane plug retention mechanism  
An osmotic delivery system has a membrane plug retention mechanism which can also be used to control the delivery rate of a beneficial agent from the osmotic delivery system. The osmotic delivery...
6978174 Methods and devices for renal nerve blocking  
A method and apparatus for treatment of cardiac and renal diseases associated with the elevated sympathetic renal nerve activity by implanting a device to block the renal nerve signals to and from...
6973718 Methods for conformal coating and sealing microchip reservoir devices  
Methods are provided for conformally coating microchip devices and for sealing reservoirs containing molecules or devices in a microchip device. One method comprises (i) providing a substrate...
6969382 Method and apparatus for treating bodily tissues with medicinal substance  
A therapeutic device and therapeutic method for delivering electrical energy to a polymer containing a medicament that allows release of the medicament to a body tissue or organ. The device and...
6960351 Implantable biocompatible immunoisolatory vehicle for delivery of selected therapeutic products  
An immunoisolatory vehicle for the implantation into an individual of cells which produce a needed product or provide a needed metabolic function. The vehicle is comprised of a core region...
6953455 Medicine delivery system  
A medicine delivery system ( 10 ) implantable into a human or animal body includes a medicine delivery unit ( 14 ) and a control unit ( 12 ). A membrane ( 26 ) seals the delivery opening ( 22 ) of...
6950707 Systems and methods for treatment of obesity and eating disorders by electrical brain stimulation and/or drug infusion  
Systems and methods for introducing one or more stimulating drugs and/or applying electrical stimulation to the brain to at least treat or prevent obesity and/or other eating disorders uses at...
6929631 Method and apparatus for percutaneously accessing a pressure activated implanted port  
Methods and apparatus for percutaneously accessing an implanted port using an access tube which is periodically introduced to the implanted port. The apparatus is preferably an implantable port...
6929637 Device and method for intra-bronchial provision of a therapeutic agent  
The present invention includes an intra-bronchial device, system, and method for providing a therapeutic agent to a patient. A device includes a flow control member for placement in an air...
6929636 Internal drug dispenser capsule medical device  
The present invention provides a swallowable internal drug medical device. The device includes a swallowable capsule. A sensing module is disposed in the capsule. A bioactive substance dispenser is...
6899697 Surgical system pump and method therefor  
The automatically controlled pump supplies pressurized irrigation fluid to a surgical site. The pump system includes a motor in a housing and a pump in a housing defining input and output ports....
6884239 Ingestible device for the release of substances at distinct locations in alimentary canal  
The field of the invention is site-specific drug delivery capsules (SSDC's). The disclosure relates to a closure member ( 14 ) for a substance reservoir ( 12 ) of an SSDC ( 10 ). The SSDC ( 10 )...
6875196 Vestibular irrigator test system (VITS)  
The present invention provides automated control of aural irrigation by utilizing a process controller in connection with an irrigation supply unit and irrigation delivery unit. Sensors situated in...
6875208 Microchip devices with improved reservoir opening  
Microchip devices and methods of manufacture thereof are provided to increase the uniformity and reliability of active exposure and release of microchip reservoir contents. In one embodiment, the...
6872200 External infusion device with remote programming, bolus estimator and/or vibration alarm capabilities  
An infusion system for infusing a liquid into a body includes an external infusion device and a remote commander. The external infusion device includes a housing, a receiver, a processor and an...
6849463 Microfabricated devices for the storage and selective exposure of chemicals and devices  
Microchip devices and methods of use are provided for the controlled exposure of a secondary device. In one embodiment, the microchip device include a substrate, a plurality of reservoirs in the...
6835194 Implantable devices and methods for treatment of pain by delivery of fentanyl and fentanyl congeners  
The invention features devices and methods for treatment of pain. The drug delivery device is a drug delivery system adapted for whole implantation in a subject and to provide pain relief by...
6808522 Microchip devices for delivery of molecules and methods of fabrication thereof  
Methods of manufacturing microchip devices are provided for controlled release of molecules, such as drugs. Methods include compression molding and casting, alone or in combination with...
6802811 Sensing, interrogating, storing, telemetering and responding medical implants  
Implants and implants, including sensors responsive to pressure, fluid flow, concentration of analytes, pH and other variables, including a feedback loop and means for modifying the implant after...
6800070 Lockable tranquilizer bracelet  
A tranquilizer bracelet which can be locked onto A wearer's wrist. The bracelet contains A power source, an electronic control module, and means for injecting A tranquilizing agent into the wearer....
6776991 Methods for treating priapism  
A method for treating priapism in a mammal by administration of a botulinum toxin.
6773428 Implantable delivery system and method for the pharmacologic management of erectile dysfunction  
An implantable delivery system of the invention for managing a patient's erectile dysfunction, generally comprises: one or more reservoir members adapted to be substantially implanted in the...