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7354392 |
Structurally optimized hollow fiber membranes
An elongated hollow microporous fiber comprises an inner wall surface defining an interior fiber lumen, an outer wall surface, and a microporous fiber wall therebetween, the fiber wall having one...
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7326182 |
Method of using device for bio-affinity material for treatment of blood or plasma
Bio-affinity material containing at least one biologically active saccharide which is covalently bound via at least one spacer to a cross-linked matrix and that the material is autoclaved....
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7291269 |
Apparatus and process for extracorporeal treatment of blood with selective extraction of solutes
A device and method for an extracorporeal blood treatment is described. The device comprising at least one exchanger equipped with at least one first inlet for the blood to be treated, a first...
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7270645 |
Apparatus for producing blood component products
A method and apparatus for producing blood component products. In one embodiment, a plurality of a predetermined type of blood component is harvested from a source of whole blood. At least two...
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7195711 |
Specialized hollow fiber membranes for in-vivo plasmapheresis and ultrafiltration
An in-vivo plasmapheresis and/or in-vivo ultrafiltration membrane comprises elongated hollow fibers each fiber having an interior lumen extending along the fiber length, the fiber wall having a...
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7195606 |
Syringe and a method for its utilization in analysis
The invention provides a syringe for preventing anemia resulting from withdrawal of blood from a patient for analysis, the syringe including a cylindrical tube having a nozzle at its lower end to...
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7186231 |
Blood component collection method
An object is to provide a blood component collection system capable of collecting a desired blood component of high quality. A blood component collection system 1 comprises a centrifugal...
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7169547 |
High concentration white blood cells as a therapeutic product
A therapeutic product formed from a high concentration of white blood cells having a high degree of cell viability. The white blood cells are sequestered from their normal population presence in...
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7115205 |
Method of simultaneous blood collection and separation using a continuous flow centrifuge having a separation channel
A system for automatically collecting and separating whole blood into its components is described. The system includes a console, which contains all motors, pumps, sensors, valves and control...
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7108672 |
Extracorporeal blood processing methods and apparatus
An extracorporeal blood processing system is disclosed which includes a variety of novel components and which may be operated in accordance with a variety of novel methodologies. For instance, the...
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7025881 |
Filter arrangement for the separation of blood into plasma and cellular components and device for application thereof on the donor
The invention relates to a filter arrangement for the separation of blood into plasma and cellular components, comprising at least one filter element with an inlet line and an outlet chamber in a...
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7001513 |
Automated processing of a biological component
A biological fluid processing device includes a multiple biological fraction container enclosing a liquid biological fraction. A rigid cassette contains at least one biological fluid processing...
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6960178 |
Apparatus for enhanced plasmapheresis and methods thereof
An apparatus and methods for enhanced plasmapheresis comprising a filter membrane under an orbital motion or movement that has optimal local shear forces and maximum plasma flow output. The methods...
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6949078 |
Apparatus and method for selective reduction of segmental intracellular and extracellular edema
Segmental edema is treated by inserting a plasma extraction filter device in a major vein of a body segment or servicing the body segment containing the edemic tissues, and inserting a return...
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6945948 |
Extra-corporeal dual stage blood processing method and apparatus
Methods and apparatus particularly involving the separation of blood into blood components and the collection of such components are disclosed. In one aspect, an extra-corporeal method for the...
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6899692 |
Plasmapheresis filter device and catheter assembly
A filter device for being implanted in a blood vessel for carrying out in-vivo plasma separation comprises one or more elongated hollow tubes and a plurality of elongated hollow microporous fibers,...
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6893412 |
Platelet collecting apparatus
A platelet collecting apparatus 1 comprises a centrifugal separator 20 possessing a rotatable rotor 142 ; a first line 21 for allowing the flow of the blood entering the centrifugal...
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6869412 |
Method and device for intravascular plasma fluid removal
Plasma fluid removal is needed in a variety of clinical conditions including congestive heart failure and moderate renal insufficiency. In order to avoid the problems inherent in extracorporeal...
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6755802 |
Whole blood sampling device
A portable hand-held blood sampling device having a self-filling capability includes a blood separation filter. The filter has a plurality of pores sized to permit passage of selected blood...
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6709413 |
Platelet gel manufacturer for use in a closed corporeal circuit
The platelet gel manufacturer includes a platelet gel applicator, a controllable platelet receptacle, a controllable coagulant receptacle, and a controllable platelet gel receptacle. The...
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6706008 |
Automated system and method for withdrawing compounds from blood
Automated systems and methods for withdrawing a selected compound from blood are disclosed. The systems and methods utilize a disposable fluid circuit mounted on a re-usable hardware component or...
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6653131 |
Method of treating systemic inflammatory response syndrome
A method for treating systemic inflammatory response syndrome (SIRS) by contacting the bodily fluid of a patient with renal tubule cells outside of the kidney.
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6652476 |
Method and apparatus for producing blood component products
A method and apparatus for producing blood component products. In one embodiment, a plurality of a predetermined type of blood component is harvested from a source of whole blood. At least two...
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6641552 |
Blood collection and separation system
A system compact enough to be located entirely beside the donor's chair, and able to process the blood while the donor is still resting in the chair after having donated the blood. The separated...
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6632191 |
System and method for separating blood components
A system for collecting red blood cells (RBCs) and other blood components that reduces the need for human intervention. A disposable set is provided having a port, an RBC container, a centrifuge...
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6607501 |
Process and apparatus for utilization of in vivo extracted plasma with tissue engineering devices, bioreactors, artificial organs, and cell therapy applications
The present invention is directed to a method of treating cells, tissues or organs using in vivo plasma separation by implanting a plasma separation filter device within a blood vessel of a...
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6423023 |
Method and apparatus for enhanced plasmapheresis
An apparatus and methods for enhanced plasmapheresis comprising a filter membrane under an orbital motion or movement that has optimal local shear forces and maximum plasma flow output. The...
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6325775 |
Self-contained, transportable blood processsing device
A blood processing device is self-contained within a case, which sized to enable hand transport. Self-contained in the case is a blood separation device, which, for example, can comprise a...
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6251284 |
Systems and methods which obtain a uniform targeted volume of concentrated red blood cells in diverse donor populations
Blood separation systems and methods draw whole blood from a blood donor selected from a population of blood donors. The whole blood of the selected blood donor has a known hematocrit value that...
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6197202 |
Systems and methods for estimating platelet counts using a spleen mobilization function
Systems and methods separate platelets from a selected donor. The systems and methods convey anticoagulated blood containing plasma and platelets from the selected donor into the separation device...
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6102883 |
Blood collection and separation process
A system compact enough to be located entirely beside the donor's chair, and able to process the blood while the donor is still resting in the chair after having donated the blood. The separated...
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6007725 |
Systems and methods for on line collection of cellular blood components that assure donor comfort
Systems and methods convey anticoagulated blood suspension from a donor into a separation device for component separation. One or more components are retained for therapeutic use, while one or more...
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5980478 |
Apparatus and method for the treatment of acute and chronic renal disease by continuous passive plasma ultrafiltration
An apparatus for treatment of acute and chronic renal disease by continuous passive plasma ultrafiltration includes a plasmapheresis element comprising a catheter and a plasmapheresis filter...
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5968004 |
Microporous membrane sheet plasma extraction catheter
An assembly for being implanted in a blood vessel for carrying out in vivo plasma separation incorporates a plasma extraction capsule formed of a microporous polymeric membrane sheet having a pore...
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5863289 |
Cross-spike prevention system
An improved device and process of assuring separation of an anticoagulant type fluid from a saline type fluid each of which is utilized in the process and operation of a plasma-pheresis apparatus...
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5858238 |
Salvage of autologous blood via selective membrane/sorption technologies
Methods and apparatuses for salvaging blood from a patient are disclosed. A blood salvaging and/or blood processing circuit coupled to a cardiopulmonary bypass circuit, cardiotomy circuit, or...
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5833866 |
Blood collection systems and methods which derive instantaneous blood component yield information during blood processing
Systems and methods for separating platelets from blood derive the yield of platelets in real time as processing is accomplished. The systems and method determine an incremental blood volume...
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5746979 |
Method for receiving and separating a fluid into its ingredients
A method of separating fluid into two or more separable fractions. One container section (2) and the adjacent portion of the other container section are made of solid material, and the two...
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5735809 |
Fiber assembly for in vivo plasma separation
An improved plasma extraction element for being implanted in a blood vessel for carrying out in vivo plasma separation comprises an elongated catheter having a fan-like assembly of elongated hollow...
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5733254 |
Method for treating patients suffering from immune thrombocytopenic purpura
Immune thrombocytopenic purpura is treated by removal of IgG and circulating immune complexes from the patient's blood. Removal is accomplished by exposing the blood or blood plasma to an...
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5679260 |
Process for simultaneously removing tumour necrosis factor α and bacterial lipopolysaccharides from an aqueous liquid
Disclosed is a process to remove tumour necrosis factor α (TNFα) or/and bacterial lipopolysaccharides (LPS) from an aqueous liquid, in particular blood, blood plasma or serum, in an...
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5676841 |
Blood processing systems and methods which monitor citrate return to the donor
Blood collection systems and methods minimize citrate toxicity in donors. The systems and methods convey whole blood at a prescribed rate Q b into a separation device for separation into red blood...
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5643794 |
Apparatus for bioprocessing a circulating fluid
The invention relates to the safe and effective biotreatment of circulating fluids. In one general aspect of the invention, an apparatus (e.g., liver assist system) for circulating and...
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5643192 |
Autologous fibrin glue and methods for its preparation and use
A fibrin glue includes a fibrinogen component and a thrombin component, both prepared from single donor plasma. The plasma is precipitated to produce a precipitate containing fibrinogen and a...
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5562836 |
Method for storing blood in a container having multiple chambers
A method for separating blood into its components and individually storing same is provided. The method has the steps of: providing a container having a body with at least a first and second...
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5516431 |
Method of washing secondary filter in process for filtering plasma
In a plasma filtration process including a treatment with a primary filter for separating blood into blood cells and plasma and a treatment with a secondary filter for removing harmful...
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5505685 |
Automation of plasma sequestration
A plasma sequestration system having a volume control system is provided. When a calculated volume of whole blood has been processed, the system switches from a fill to an empty cycle. The...
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5494592 |
Apheresis apparatus and method
An apheresis apparatus and method is disclosed for increasing the purity and yield of platelets separated from donated whole blood in a centrifuge. The whole blood in the centrifuge is diluted by...
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5494578 |
Centrifugation pheresis system
A system and method of separation of therapeutic components from blood. The system includes a dual member centrifuge and a disposable single use fluid transfer set. The set includes an elongated...
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5480378 |
Apparatus for preparing a concentrate of coagulation factors from a blood sample
An apparatus for preparing a concentrate of coagulation factors, such as fibrinogen, from a blood sample, comprises a first chamber (14) for collection and separation of said blood sample so as to...
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