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7547281 |
Algorithm sensor augmented bolus estimator for semi-closed loop infusion system
An infusion system is for infusing a fluid into the body of a patient. The infusion system includes at least one sensor for monitoring blood glucose concentration of the patient and an infusion...
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7452532 |
Transluminal application of adult stem cells for body organ tissue repair
A method for repairing tissue of a selected organ from among heart, brain, liver, pancreas, kidney, glands, and muscles in a patient's body. Adult stem cells that have the capability to repair...
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7452344 |
Platelet concentration syringe kit
A single-use system for separating blood and producing platelet concentrates includes an elongated container for receiving blood from a patient. The container has a movable plunger mounted within...
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7270655 |
Autologous material delivery apparatus and method
An apparatus and method for providing autologous medical treatment to a patient. The apparatus is characterized by its provision of a harvest catheter operatively connected to a pump and a delivery...
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RE39533 |
Process for intra-uterine fertilization in mammals and device for implementation thereof
The A fertilization process comprises includes the following steps: a) a container ( 15 ) which can be introduced into, and lodged in, the uterine cavity of the mammal is provided; b) the...
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6979308 |
Bioreactor design and process for engineering tissue from cells
A scaled-up multi-coaxial fiber bioreactor, and variations of this bioreactor. The device is characterized by a hollow housing and an array of from about 20 to about 400 modules of hollow fibers,...
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6958060 |
Method for muscle delivery of drugs, nucleic acids and other compounds
A method is disclosed for delivering molecules such as pharmaceutical drugs and nucleic acids into skeletal muscle in vivo. The molecule is first injected into the muscle at one or multiple sites....
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6899877 |
Process for generating plasmin in the vitreous of the eye and inducing separation of the posterior hyaloid from the retina
A process for inhibiting vascular proliferation separately introduces components into the eye to generate plasmin in the eye in amounts to induce complete posterior vitreous detachment where the...
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6862479 |
Spinal cord stimulation as a therapy for sexual dysfunction
One or more implantable system control units (SCU) apply one or more stimulating drugs and/or electrical pulses to a spinal section responsible for innervating the male reproductive organs. The SCU...
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6846306 |
Single cell electroporation
A single cell electroporation assembly and method involve delivery of a substance into a single cell. The substance is combined into an electroporation fluid and placed into a container having a...
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6821264 |
Gene delivery device and gene delivery method
A gene delivery device for localizing and enhancing the efficacy of gene transfer that provides a contact surface for contacting with a tissue site. By applying a pharmaceutical composition...
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6805860 |
Method of transluminal application of myogenic cells for repair or replacement of heart tissue
A process is described for cellular repair of failing tissue of an organ if a patient's body. In the process, a catheter is positioned to provide an entry point for stem cell injection at the...
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6758828 |
Catheter for cell delivery in tissue
An apparatus delivers an agent to a treatment region, the apparatus having an outer cannula or lumen that has an internal surface and an external surface, the external surface being substantially...
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6746441 |
Flow-through electroporation system for ex vivo gene therapy
A method and apparatus for introducing a preselected molecule into a living cell by contacting the cell with the preselected molecule and applying a multiple series of electrical pulses to the...
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6719738 |
Device for directly delivering an active substance within a cell tissue, means for implanting said device and appliances for injecting active substance into said device
The invention concerns a device for directly delivering an active substance within all or part of a human or animal tissue cell, characterized in that it is in the form of a hollow tube ( 1 ),...
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6685695 |
Method and apparatus for providing nutrition to intervertebral disc tissue
An intervertebral disc is treated by providing supplemental nutrition to increase viability and longevity. In the preferred embodiment, the invention uses one or more porous stents that function to...
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6659995 |
Autologous myocyte micro granual retrieval and implantation (AMMGRI)
In a method for autologous myocardial implantation treatment, a donor area of a patient containing healthy skeletal muscle is located. Myocyte micro granules are retrieved from the donor area using...
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6623472 |
Method for inducing therapeutically-effective proteins
A method for inducing therapeutically-effective protein includes selecting a syringe having inner structures coated with an inductor, disposing a therapeutically-effective protein therein with a...
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6610044 |
Method for genetic immunization
A method is disclosed for enhanced vaccination and genetic vaccination of mammals. The vaccination is accomplished by delivering molecules such as proteins and nucleic acids into skeletal muscle...
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6599274 |
Cell delivery catheter and method
A cell delivery catheter having one of more apearutres is used to positon and deliver cells to an implant site in a patient.
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6595979 |
Methods for sterile aspiration/reinjection of bodily fluid
Methods for aspiration and filtering of a bodily fluid containing undesired components are provided and for treatment of the bodily fluids in a sterile environment in preparation for reinjection of...
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6585972 |
Process for crosslinking of collagen in the vitreous of the eye and inducing separation of the posterior hyaloid from the retina
A process for inhibiting vascular proliferation introduces a composition into the eye inducing posterior vitreous detachment. The composition includes a combination of plasminogen, a collagen...
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6569149 |
Method of treatment using electroporation mediated delivery of drugs and genes
A method for in vivo electrotherapy, or electroporation-mediated therapy, using a needle array apparatus is provided. Treatment of tumors with a combination of electroporation using the apparatus...
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6530912 |
Apparatus for connecting a compatibility liner with a source of perishable therapeutic
An apparatus for connecting a compatibility liner with a source of perishable therapeutic is provided. In one exemplary system for connecting a reservoir of perishable therapeutic with a lumen, a...
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6527760 |
Out-patient joint lavage kit and protocol
Out-patient knee lavage is performed by use of a kit comprising: A. Means for preparing the knee joint for lavage; B. An optional surgical drape; C. A first needle and a first syringe containing a...
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6527759 |
Ultrasound assembly for use with light activated drugs
A kit and method for causing tissue death within a tissue site is disclosed. The kit includes a media with a light activated drug activatable upon exposure to a particular level of ultrasound...
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6519492 |
Method and apparatus for direct in vivo gene transfer by electrotransfection
This invention is directed to a novel method for direct in vivo electrotransfection of a plurality of cells of a target tissue. In the method, the target is perfused with a transfection solution....
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6426332 |
Matrix-free osteogenic devices, implants and methods of use thereof
Provided herein are methods for inducing bone formation in a mammal sufficient to fill a defect defining a void, wherein osteogenic protein is provided alone or dispersed in a biocompatible...
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6402733 |
Intrapulmonary delivery of polypeptide growth factors and cytokines
Polypeptides selected from the group of growth factors and cytokines are administered by intrapulmonary inhalation. Disclosed are novel compositions and devices for effecting the intrapulmonary...
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6368298 |
Preparing autologous fibrin glue
A method of preparing a solid-fibrin web is disclosed. The method includes drawing blood from a patient, separating plasma from the blood, contacting the plasma with a calcium-coagulation activator...
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6358917 |
Cosmetic use of botulinum toxin for treatment of downturned mouth
This invention provides the use of Botulinum toxin (BTX) to cause paralysis of a depressor anguli oris (DAO) musculature in a patient to alleviate downturn at corners of the patient's mouth.
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6356784 |
Method of treating movement disorders by electrical stimulation and/or drug infusion of the pendunulopontine nucleus
The present invention discloses techniques for treating movement disorders by electrical stimulation and/or drug infusion. The present invention utilizes an implantable signal generator and an...
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6331175 |
Method and kit for imaging and treating organs and tissues
Provided are methods and compositions for detecting and treating normal, hypoplastic, ectopic or remnant tissue, organ or cells in a mammal. The method comprises parenterally injecting a mammalian...
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6309381 |
Use of human growth hormone to treat acute myocardial infarction
A method of treating an acute myocardial infarction (AMI) using human growth hormone to prevent most of the complications and the destructive process of cells and collagen framework which are...
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6299590 |
Implant, and method and device for inserting the implant
A ball-shaped implant made out of a pliable fiber. The fiber is introduced into the body and when it encounters body tissue it folds upon itself to form a ball-shaped implant. A fluid may be placed...
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6296632 |
Ball-shaped fiber implant, and method and device for inserting the implant
In the method proposed, the implant material in the form of a fibre is unwound from a bobbin (10) with the aid of a stream of air (24) and injected through a tube (19) into the body (22). In front...
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6264646 |
Method for preventing and reversing atherosclerosis in mammals
A method for delaying the onset, retarding the progression, and causing regression of atherosclerosis in a mammal comprises: (a) treating an aliquot of mammalian blood ex vivo with at least one...
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6179826 |
Implantable therapy systems and methods
Implantable therapy systems are disclosed for the local and controlled delivery of a biologically active factor to the brain, spinal cord and other target regions of a subject suffering from a...
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6176871 |
Apparatus and methods for intraluminal photothermoforming
A method and apparatus for molding polymeric structures in vivo is disclosed. The structures comprise polymers that may be heated to their molding temperature by absorption of visible or...
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6174299 |
Method for treating hemophilia A and B and AIDS and devices used therein
The present invention provides a method for treating Hemophilia A or B which comprises implanting in fluid communication with the bloodstream of a mammal in need of such treatment a permeable...
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6168587 |
Needleless syringe using supersonic gas flow for particle delivery
A needleless syringe having a membrane (28) which is ruptured by gas pressure to generate a supersonic gas flow in which particles containing a therapeutic agent are injected.
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5665372 |
Autologous dermal fibroblasts for the repair of skin and soft tissue defects
The application concerns a method of repairing sequelae of acne vulgaris in a subject which comprises the steps of: a) providing a fibroblast-seeded clot having dermal fibroblasts derived from the...
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5656267 |
Implantable cells that alleviate chronic pain in humans
This invention provides a method of alleviating chronic pain in humans. Viable, implantable cells are selected which release neuroactive substances that reduce chronic pain. The cells are cultured...
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5652225 |
Methods and products for nucleic acid delivery
The present invention provides a method for the delivery of a nucleic acid to an arterial cell comprising contacting the cell with a hydrophilic polymer incorporating the nucleic acid. The nucleic...
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5609571 |
Apparatus and method of cardioplegia delivery
A cardioplegia delivery device and method of use for delivering warm or cold cardioplegia fluid to the heart of a patient. The delivery device includes an air chamber having a housing with an...
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5609629 |
Coated implantable medical device
A coated implantable medical device 10 includes a structure 12 adapted for introduction into the vascular system, esophagus, trachea, colon, biliary tract, or urinary tract; at least one layer 18...
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5599307 |
Catheter and method for the prevention and/or treatment of stenotic processes of vessels and cavities
A catheter for preventing the stenosis or restenosis of a body vessel or cavity, e.g., a blood vessel, whereby a membrane may be applied to the inner surface of the vessel or cavity. The inventive...
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5593974 |
Localized oligonucleotide therapy
Disclosed is a method for localized application of antisense oligonucleotides, which has been found to be effective in inhibiting expression and translation of a variety of genes. The method...
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5584804 |
Brain resuscitation and organ preservation device and method for performing the same
The invention discloses methods for preserving organs in brain-dead humans or cadavers which allows additional time for the organs to remain viable such that they may be harvested for subsequent...
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5571083 |
Method and system for cell transplantation
A system and method are disclosed for internally delivering cellular transplants to a patient under the automatic control of a computer. A diagnostic imaging modality, such as a CAT or MRI scanning...
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