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7553319 |
Auto-injector apparatus and methods for sealing a vascular puncture
Apparatus for sealing a puncture communicating with a blood vessel includes a pair of syringe barrels having sealing components therein, and a plunger assembly biased to slide within the barrels...
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7549978 |
Needle assembly
A needle assembly has a first body and a guide rod supported for sliding movement between an extended position and a retracted position. A second body is attached to the guide rod. The second body...
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7503913 |
Methods and compositions for use in perfusion applications
Methods and compositions for use in perfusion applications are provided. In the subject methods, a subject or derivative thereof, e.g. isolated organ or tissue, is infused, perfused and/or...
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7500970 |
Catheter drug delivery system and method for use
A catheter system for injecting therapeutic agents including large molecules into the body. The catheter includes a distensible penetrating element with a distally locating expansion coil and a...
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7481803 |
Intra-aortic renal drug delivery catheter
A catheter for delivering a therapeutic or diagnostic agent to a branch blood vessel of a major blood vessel, generally comprising an elongated shaft having at least one lumen in fluid...
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7473247 |
Intradermal delivery of vaccines and gene therapeutic agents via microcannula
The present invention relates to methods and devices for administration of vaccines and gene therapeutic agents into the intradermal layer of skin.
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7452344 |
Platelet concentration syringe kit
A single-use system for separating blood and producing platelet concentrates includes an elongated container for receiving blood from a patient. The container has a movable plunger mounted within...
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7431717 |
Central nervous system administration of medications by means of pelvic venous catheterization and reversal of Batson's Plexus
An infusor system for administering medications to a venous blood vessel in the body of a patient. The infusor system includes a flexible, elongated delivery tube having opposite ends. One of the...
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7419482 |
Systems and methods for delivering agents into targeted tissue of a living being
A method of vascularizing cardiac tissue using an instrument through the vascular system to an entry situs located at or adjacent the cardiac tissue is provided including providing a flowable agent...
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7413556 |
Sheath for use with an ultrasound element
A system for delivering ultrasound energy to a treatment section in a vessel is disclosed. The system includes a sheath with a utility lumen and an energy delivery section at least partially...
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7371228 |
Delivery of therapeutics to treat aneurysms
A method and device for the treatment of an aneurysm are provided. Different therapeutic agents are delivered to the aneurysmal site by a reservoir and delivery means in a localized, and, in some...
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7322960 |
Catheter with puncture sensor
A catheter for percutaneous insertion includes a sheath portion, an insertion member, an injection needle, and paired electrodes. The sheath portion has a lumen extending therein. The insertion...
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7314466 |
Minimally invasive vascular surgery
A mixture for intravenous injection to treat damaged vascular structures contains a mixture of carbamide peroxide and a sclerosing agent. The injected mixture expresses blood from the affected...
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7302289 |
Readable probe array for in-vivo use
A disposable high density optically readable polydeoxynucleotide array with integral fluorescence excitation and fluorescence emission channels is described. The compact array size allows...
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7241284 |
Method of inhibiting restenosis
A method of inhibiting restenosis is disclosed. The method includes reducing contaminants during manufacturing of angioplasty devices and during angioplasty procedures. An angioplasty device is...
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7182755 |
Method and apparatus for treatment of thrombosed hemodialysis access grafts
A method for the treatment of thrombosed hemodialysis access grafts or fistulas defining a shunt positioned between an arterial side and a venous side is achieved by inserting a balloon catheter...
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7166097 |
Cerebral perfusion augmentation
Methods are provided for partial aortic occlusion for cerebral perfusion augmentation in patients suffering from global or focal cerebral ischemia. The descending aorta is accessed. A device is...
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7122541 |
Methods of inhibiting metastases
The invention relates to methods for preventing and treating disseminating cancers. Inhibition metastases of a primary tumor to a liver tissue is carried out by directly contacting a liver tissue...
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7033344 |
Methods for reducing distal embolization
A method for reducing distal embolization during insertion of devices to treat plaque, thrombi and other intravascular occlusions. Using a guide catheter, a guidewire is delivered to a site...
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7011654 |
Dilating and support apparatus with disease inhibitors and methods for use
A dilating and support apparatus with disease inhibitors and methods for use is disclosed that is particularly useful for repairing and/or serving as a conduit for body passageways that require...
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7008411 |
Method and apparatus for treating vulnerable plaque
An apparatus and method to treat vulnerable plaque. In one embodiment, the apparatus has an elongated catheter body adapted for insertion in a body lumen, with a drug delivery device attached near...
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6969379 |
Intravascular cannulation apparatus and methods of use
This invention is a cannulation apparatus, and related methods for providing indirect access to a surgical site within a patient. The cannulation apparatus includes at least two fluid flow paths...
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6835193 |
Methods for controlled depth injections into interior body cavities
A flexible tissue injection catheter is used to accomplish injections at a precisely controlled depth of precisely controlled volumes of a therapeutic or diagnostic agent into an interior body...
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6827711 |
Nested tubing sections and method for making same
The invention provides a nested tubing cannula which comprises outer and inner elongate tubular members, both having a proximal end, a distal end, and a lumen therebetween. The inner tubular member...
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6808518 |
Methods and devices for treating diseased blood vessels
The present invention provides a mechanism by which the physical properties of diseased blood vessel walls can be manipulated to achieve an effective vessel lumen diameter for a prolonged period of...
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6790204 |
Method for containing and removing occlusions in the carotid arteries
A method for the treatment of a stenosis or an occlusion in a blood vessel is disclosed in which a main catheter is first delivered to a site proximal to the occlusion. The main catheter may...
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6776991 |
Methods for treating priapism
A method for treating priapism in a mammal by administration of a botulinum toxin.
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6767345 |
Partial aortic occlusion devices and methods for renal and coronary perfusion augmentation
A method for increasing renal and/or coronary blood flow. A catheter is inserted into the descending aorta. An expandable member on a distal region of the catheter is positioned in the aorta...
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6753328 |
Methods of inhibiting metastases
The invention relates to methods for preventing and treating disseminating cancers. Inhibition metastases of a primary tumor to a liver tissue is carried out by directly contacting a liver tissue...
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6723085 |
Arterial filter with aspiration and methods of use
A filter comprising a porous material is arranged in a generally conical shape having an expandable base and a vertex. An elongate member having a proximal end and a distal end is attached to the...
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6719747 |
Proton generating catheters and methods for their use in enhancing fluid flow through a vascular site occupied by a calcified vascular occulation
Catheter devices and methods are provided for enhancing fluid flow through a vascular site occupied by a calcified lesion. The catheter devices of the subject invention at least include, at their...
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6699231 |
Methods and apparatus for perfusion of isolated tissue structure
Organs and other tissue structures are isolated and perfused with a therapeutic agent. Isolation is effected by endovascularly positioning catheters having occlusion balloons within the arteries or...
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6682481 |
Resuscitation from shock
Methods, software, and apparatuses are described for resuscitation of shock due to trauma and/or hemorrhage. A representative embodiment involves a method of treating shock in a patient. A...
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6669662 |
Perfusion catheter
A perfusion catheter with a shaft having a lumen and a plurality of ports through the shaft. A rotatable core with a core groove is disposed within the lumen. The plurality of ports can be exposed...
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6659995 |
Autologous myocyte micro granual retrieval and implantation (AMMGRI)
In a method for autologous myocardial implantation treatment, a donor area of a patient containing healthy skeletal muscle is located. Myocyte micro granules are retrieved from the donor area using...
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6632223 |
Pulmonary vein ablation stent and method
A system for treating atrial fibrillation includes a stent and a delivery catheter for carrying the stent to a treatment site. The stent is self-expanding, for example, being formed of a shape...
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6613037 |
Methods and apparatus for treating aneurysms and arterio-venous fistulas
Methods and apparatus are provided for temporarily excluding an aneurysm or an arterio-venous fistula from a flow path by transluminally disposing a hollow balloon catheter structure within the...
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6599282 |
Intravenous set flow volumetric measurement device
A method and device for volumetric measurement of a drop of fluid administered in a gravity intravenous set. Radiation, preferable infrared light is passed through from the exterior of the drip...
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6599266 |
Occlusion cannula and methods of use
The invention provides a nested tubing cannula which comprises outer and inner elongate tubular members, each having a proximal end, a distal end, and a lumen therebetween. The inner tubular member...
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6592568 |
Balloon assembly for stent delivery catheter
The present invention discloses a stent delivery catheter that reduces stent displacement during deployment. In particular, the stent delivery catheter provides expansion of a stent that originates...
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6589224 |
Method of introducing fluids into a patient's body
A method of introducing a fluid into a patient's body has the steps of accommodating the fluid in a plastic container, connecting an introducer to the plastic container so that the fluid can flow...
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6569148 |
Methods for emboli containment
A multi-catheter emboli containment system is disclosed which is adapted to provide at least one pair of optimized paths for irrigation and aspiration fluid flow. Through careful design of the...
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6561996 |
Apparatus and method for in vivo hemodialysis
A method of removing toxins from a patient's blood comprises implanting a filter device having a dialysis membrane with an exterior surface exposed to the patient's blood and a dialysate cavity...
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6547753 |
Pulsatile flow generation in heart-lung machines
Pulsatile blood flow in a heart-lung machine is accomplished by pumping blood into a bladder at a constant rate, and cyclically emptying the bladder into aortic line of the heart-lung machine...
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6541116 |
Superoxide dismutase or superoxide dismutase mimic coating for an intracorporeal medical device
A method of providing a therapeutic, diagnostic or lubricious hydrophilic coating on an intracorporeal medical device and the coated device produced thereby, wherein the coating is durable. In one...
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6540733 |
Proton generating catheters and methods for their use in enhancing fluid flow through a vascular site occupied by a calcified vascular occlusion
Catheter devices and methods are provided for enhancing fluid flow through a vascular site occupied by a calcified lesion. The catheter devices of the subject invention at least include, at their...
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6540732 |
Fluid collection device with captured retractable needle
A retractable needle fluid transfer device is provided. The device includes a manually operable actuator for affecting retraction. Upon depressing the actuator, a spring displaces the needle...
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6538026 |
Compositions useful for remodeling body spaces
A composition comprising of a monomer component comprised of at least one alkyl cyanoacrylate and at least one inhibitor, and a second component comprised of a resultant aggregate structure formed...
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6537243 |
Device and method for obtaining interstitial fluid from a patient for diagnostic tests
A device for obtaining a sample of interstitial fluid from a patient for use in monitoring the level of blood glucose in the patient. The device comprises a hollow tube having a wall surrounding a...
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6533751 |
Micro catheter and guidewire system having improved pushability and control
A micro catheter and guidewire system for use in tortuous regions of a vasculature includes a catheter body having a distal end, a guidewire lumen, a proximal region with an outer diameter, and a...
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