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6723318 Targeting of biomolecules  
The present invention provide methods to improve the treatment of cancer in mammals, including ovarian cancer, where intraperitoneal administration of cytotoxic medical agents or immunoconjugates...
6719738 Device for directly delivering an active substance within a cell tissue, means for implanting said device and appliances for injecting active substance into said device  
The invention concerns a device for directly delivering an active substance within all or part of a human or animal tissue cell, characterized in that it is in the form of a hollow tube ( 1 ),...
6699211 Method and apparatus for treatment of glaucoma  
A new and improved method and apparatus for treating glaucoma is described herein. A device for directing aqueous humor from an anterior chamber to Schlemm's canal comprises a seton, and may...
6699212 Phaco thermal control apparatus and method  
Control apparatus for an ultrasonic phacoemulsification handpiece utilizes flow rates and temperature measurements as well as power provided to a handpiece for calculating a matrix of power level...
6696430 Use of vital dye for facilitating surgical procedures for vitreo-retinal surgery  
A method for performing retinal membrane removal is disclosed using vital dyes which are applied to the membrane. Compositions including vital dyes which are useful in the retinal membrane removal...
6689070 Devices, methods and systems for collecting material from a breast duct  
The invention provides methods, devices and systems for collecting breast ductal fluid comprising cellular material and other useful markers for analysis. The methods typically comprise access of...
6685678 Drug delivery and monitoring system  
A drug administration system includes a cradle attached about an intravenous injection port having a flange extending therefrom. The cradle supports first drug administration information in the...
6682545 System and device for preventing restenosis in body vessels  
The present invention relates to a system and device for preventing stenosis and/or restenosis after an invasive procedure in a body vessel or cavity having an inner wall surface, the system...
6679859 Amelioration of ischemic damage using synthetic oxygen carriers  
A method of ameliorating tissue damage resulting from hypoxia or ischemia by administering systemically a synthetic oxygen carrier to an individual having or suspected of having blood vessel...
6676622 Extracorporeal affinity adsorption methods for the treatment of atherosclerosis, cancer, degenerative and autoimmune diseases  
Extracorporeal affinity adsorption treatments which are aimed at the substantial removal of two or more compounds that are etiological in the pathogenesis of diseases in man provide effective...
6673024 Cytological evaluation of breast duct epithelial cells retrieved by ductal lavage  
Methods and systems for cytologically evaluating breast duct epithelial cells retrieved by ductal lavage by morphology and other parameters.
6669661 Method and device for central nervous system protection during whole body hyperthermia or hypothermia  
A method and device for intentionally inducing whole-body hyperthermia or hypothermia in a patient for medical treatment while protecting the central nervous system from damage includes a tub for...
6666841 Bifurcatable trabecular shunt for glaucoma treatment  
A trabecular shunt and methods for treating glaucoma are disclosed. The method comprises placing a trabecular shunt through diseased trabecular meshwork, between the anterior chamber and Schlemm's...
6663829 Method and apparatus for reducing the degradation of heat sensitive components in medical substances during heat sterilization  
Methods and apparatus are disclosed for reducing the degradation of heat sensitive components contained in a medical substance during heat sterilization of a heat sterilizable container including a...
6656147 Method and delivery device for the transdermal administration of a substance  
A device for delivering a substance into the skin of a patient includes a housing and a plurality of microneedles for penetrating the skin. The housing includes a bottom wall with a plurality of...
6652818 Implant sterilization apparatus  
This invention includes a novel method for safely, effectively and efficiently pooling of tissues for treatment prior to implantation into a recipient in need thereof. In one embodiment, the method...
6645167 Methods for embolizing vascular sites with an embolizing composition  
Disclosed are novel methods for embolizing blood vessels comprising delivering, via a catheter, an embolic composition comprising a biocompatible polymer, a biocompatible water insoluble contrast...
6641566 Reusable medication delivery device  
A medication injection or delivery system is provided for injecting fluids such as insulin within body tissue. The device includes a housing, a flexible shaft movably mounted within the housing,...
6641572 Interstitial space saturation  
Providing a means for perfusing a high concentration of medication to treat a lesion, specifically cancer, infection, or autoimmune process, while averting the leakage of a substantial quantity of...
6626859 High performance cannulas  
A cannula having a proximal end, a distal end, and a lumen extending between the proximal and distal ends is provided. The diameter of the lumen of the cannula can be varied to take into account...
6620120 Method for high efficiency hemofiltration  
Disclosed herein is an apparatus that efficiently clears solutes from blood of patients with renal disease solely by convection and with a single filter that includes a hemofilter, a blood pump for...
6620139 Catheter system for performing intramyocardiac therapeutic treatment  
The multilumen catheter ( 2 ) is provided at one end with a needle system ( 9, 9 ′) formed by two or more single-lumen needles which are provided with respective discharge openings ( 110, 111 )...
6595941 Methods for external treatment of blood  
Vascular access systems, devices and methods for facilitating repeated access to a blood vessel. These systems, devices and methods can be used in external blood treatment, such as dialysis, and in...
6596234 Reversing flow blood processing system  
A tubular set is provided for the extracorporeal treatment of blood, for example hemodialysis. The set has a patient arterial line and a patient venous line, each line having a patient connector at...
6585682 Method and apparatus for preventing protein loss with peritoneal dialysis  
Methods of peritoneal dialysis are disclosed including draining spent peritoneal dialysis solution from a patient to a drain bag, passing the spent peritoneal dialysis solution from the drain bag...
6561996 Apparatus and method for in vivo hemodialysis  
A method of removing toxins from a patient's blood comprises implanting a filter device having a dialysis membrane with an exterior surface exposed to the patient's blood and a dialysate cavity...
6558343 Device for peritoneal dialysis and method for using said device  
The present invention relates to the treatment of kidney insufficiency and more particularly to a peritoneal dialysis device. The device is adapted to function in tidal peritoneal dialysis (TPD)...
6551302 Steerable catheter with tip alignment and surface contact detector  
A steerable percutaneous catheter for guiding at least one functional device to selected surfaces of a body for treatment thereon, particularly adapted for laser-assisted Percutaneous...
6544206 Dialysis access system and method  
A method of and system for providing vascular access in a patient for hemodialysis involves attaching the distal end of an access catheter to the abdominal aorta of the patient and the proximal end...
6544211 Tissue liquefaction and aspiration  
A method and apparatus are disclosed for liquefying target tissue within a body and aspirating the same while leaving non-target tissue intact. A biocompatible fluid is heated and contacted with...
6544210 Disposable laparoscopic smoke evacuation system  
A disposable laparoscopic smoke evacuation system. The system utilizes a small fan unit and filter housed in a single disposable housing adapted to be connected between two laparoscopic surgical...
6537243 Device and method for obtaining interstitial fluid from a patient for diagnostic tests  
A device for obtaining a sample of interstitial fluid from a patient for use in monitoring the level of blood glucose in the patient. The device comprises a hollow tube having a wall surrounding a...
6537241 System and method for site specific therapy  
A system, including catheter apparatus, and related method for performing site specific therapy. The catheter apparatus can include one or more semipermeable microcatheters (preferably in the form...
6517510 Automatic patient control device  
The present invention relates to regulating the temperature of a desired medium that is applied to the exterior surface of a mammal. These devices have been used in the past but not with the...
6494859 Methods using pressure to obtain fluids and cellular material from breast ducts  
Methods, kits, and apparatus for obtaining cellular, chemical, and other materials from breast ducts are described. A single milk duct is accessed and washed with a washing fluid to obtain marker...
6485450 Brain resuscitation apparatus and method  
A resuscitation apparatus includes a fluid pathway in fluid communication with a source of medical fluid, an interface unit for attaching the fluid pathway to the cardiovascular system of a mammal...
6484050 Minimally invasive surgical instrument for tissue identification, dislodgment and retrieval and methods of use  
A probe or sheath for use on a probe for detecting and removing radioactively tagged tissue, e.g., a sentinel lymph node, within the body of a living being. The probe or sheath and probe is...
6471667 Medical suctioning methods  
A medical fluid suctioning device for selectively applying varied levels of suction pressure at a device-tissue interface includes a direct “trumpet”-type control mechanism in conjunction with...
6470889 Method for injecting a contrast medium to generate prolonged uniform vascular enhancement  
A contrast medium injector for injecting a patient with contrast medium for a CT scan is programmed to provide an injection protocol that is a representation of an ideally defined exponential curve...
6458323 Method and device for the vascular pressure-controlled selective perfusion of fluids through blood vessels  
A method for selective perfusion of fluids through blood vessels is controlled by the pressure in the blood vessels. A tubing line open at the proximal end for the perfusion of fluids through a...
6455027 Methods and kits for identifying ductal orifices in a nipple  
Methods, kits, and apparatus for locating, labelling, and accessing breast ducts are described. An orifice to one or more ductal networks is marked to enhance visibility. In a first embodiment, the...
6428502 Punctal cannula  
A lacrimal cannula, which is used for the removal of plugs or obstructions from mammalian lacrimal canaliculi having a punctum, includes a body having a distal portion, a proximal portion, an...
6423028 Process for generating a pulsatile stream of a pulsed-suctioned sterile fluid jet and resulting pulsed jet for a handpiece, in particular for surgical use  
The process consists in generating a firing pulse pattern characterized in that it implements a pressurized liquid channel and a pneumatic aspiration channel and in that the periodic firing of the...
6413233 Perfusion hyperthermia treatment system and method  
Method and apparatus to automatically monitor and control a perfusion hyperthermia treatment using a system including one or more programmed computers, and mechanical and sensor subsystems. The...
6401975 Pressurized fluid delivery apparatus  
A fluid delivery apparatus is provided that includes a pressure tube and a first cap assembly having a control system, with the first cap assembly coupled to a first end of the pressure tube for...
6398773 Aspiration system and method  
Aspiration catheters and methods for the treatment of an occlusion in a blood vessel. These catheters and methods are especially useful in the removal of occlusions from saphenous vein grafts, the...
6391016 Methods for trephination and irrigation of the frontal sinus cavity  
A method of trephination and irrigation involves treating the frontal sinus through a hole drilled through the frontal bone. A small incision is made large enough to accept a soft tissue sleeve...
6383162 Apparatus and method for abdomino-pelvic chemotherapy perfusion and lavage  
An abdomino-pelvic perfusion and lavage apparatus is disclosed to which skin surrounding an incision formed through an abdominal wall of a patient can be attached and suspended. The apparatus...
6379331 Medical device for selective intrathecal spinal cooling in aortic surgery and spinal trauma  
The invention provides a medical device having two elongate catheters, a pump, a refrigeration system, and a manometer. Each catheter has a proximal end, a distal end, a lumen therebetween and...
6325475 Devices for presenting airborne materials to the nose  
An ink-jet dispenser for the micro-dispensation of airborne materials into an individual's airspace for inhalation or sniffing. The ink-jet dispenser will allow the study of temporal integration...