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7621895 |
Needle array devices and methods
Methods and delivery devices for maximizing injectate dispersion in lesioned tissue using needle-based injection devices are herein disclosed. The delivery devices include injection devices with...
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7597687 |
Injection of fibrin sealant including an anesthetic in spinal applications
A method of treating a disc that is leaking nucleus pulposus through at least one defect in the annulus fibrosus. The method includes injecting a fibrin sealant into the disc to reduce at least a...
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7591807 |
Penetrating injection needle
A penetrating injection needle for the injection of a pharmaceutical product into a human or animal body. The needle includes a tubular body having two opposing ends, a first end for connection to...
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7591806 |
High-aspect-ratio microdevices and methods for transdermal delivery and sampling of active substances
High-aspect-ratio microdevices comprising microneedles, microknives and microblades and their manufacturing methods are disclosed. These devices can be used for the delivery of therapeutic agents...
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7569044 |
Safety needle with positive flush
A needle assembly including a positive flush mechanism for use with a vascular access port. The needle assembly is configured to supply fluid to the port and to provide a positive flush to overcome...
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7547294 |
Microfabricated surgical device for interventional procedures
An actuator for an interventional surgical procedure is described. The actuator may include an actuator body having a distal end and a proximal end. A central expandable section is located between...
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7494478 |
Catheter assembly
A catheter assembly comprises an outer catheter comprising a distal end curved portion having a first curved shape, and an inner catheter which comprises a distal end curved portion having a second...
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7481826 |
Fluid emitting suture needle
A multifunctional suture needle that may be used to draw a suture through tissue surrounding a wound while simultaneously delivering a bioactive fluid through the needle tip. The suture needle...
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7473244 |
Active needle devices with integrated functionality
An active needle device for fluid injection or extraction includes at least one hollow elongated shaft defining at least one channel. The channel provides communication between at least one input...
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7470255 |
Introducer assembly with suspended seal
A surgical access apparatus includes an access member dimensioned for insertion within tissue and having a longitudinal opening to permit introduction of a surgical object through the access member...
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7448868 |
Tool holder for flexibly-deformable tool
The invention relates to a tool holder ( 1 ) which is intended to receive a flexibly-deformable tool ( 12 ), such as an injection needle or a cutting tool. The operating direction ( 15 ) of the...
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7435240 |
Flexible injection needle
An injection needle, for injection into a body tissue, is flexible in the introduced or post-inserted state and comprises a channel for the introduction of a fluid. The injection needle is at least...
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7435239 |
Injection needle with needle point offset from central plane
An injection needle that can reduce the pain associated with piercing a patient's skin with a needle. The needle has a needle tip provided by forming at least two or more ground surfaces after a...
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7416541 |
Intracutaneous microneedle array apparatus
Improved microneedle arrays are provided having a sufficiently large separation distance between each of the individual microneedles to ensure penetration of the skin while having a sufficiently...
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7402163 |
Device for controlled endoscopic penetration of injection needle
An endoscopic needle device includes a handle and a catheter sheath connected to the handle, wherein the catheter sheath has at least one lumen, for example a needle lumen and a stabilization...
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7402155 |
Injection apparatus for delivering therapeutic
A catheter for delivering therapeutic to an injection site within the body is provided. This catheter can include a shaft having a proximal end, a distal end, and an infusion lumen extending...
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7393344 |
Hypodermic syringe needle assembly and method of making the same
A retractable needle assembly for use in medical procedures comprising a needle assembly including a hub, a hollow needle passing through the hub and projecting from the posterior end of the hub. A...
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7344518 |
Apparatus for delivering ablation fluid to treat lesions
A surgical apparatus for delivering fluid to treat a lesion comprising an elongated member having a distal tip and a plurality of slots formed in a sidewall proximal of the distal tip, a plurality...
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7331943 |
Injection needle for sclerotherapy
An injection needle ( 1 ) particularly adapted for sclerotherapy is disclosed, comprising a cannula ( 2 ) with mainly longitudinal development defining a main axis (X), a duct ( 4 ) for passage of...
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7291497 |
Medical device for analyte monitoring and drug delivery
The invention relates to an ingestible, implantable or wearable medical device comprising a microarray which comprises a bioactive agent capable of interacting with a disease marker biological...
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7285113 |
Systems and methods for the transport of fluids through a biological barrier and production techniques for such systems
A device for the transport of fluids through a biological barrier includes a number of microneedles projecting from the front face of a substrate. A conduit is associated with each of the...
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7273489 |
Device for occluding a hole in a body wall and a unit for inserting said device
The device includes a solid disk ( 1 ) whose diameter is larger than the diameter of a hole ( 2 ) to be treated and which is formed by a peripheral deformable thread ( 6 ) made of a shape memory...
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7273474 |
Flexible substrate structure for microneedle arrays and its manufacturing method
The present invention is related to a flexible substrate structure for microneedle arrays and its manufacturing method, whose structure mainly comprising: tapered shape objects and flexible...
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7252654 |
Apparatus with weeping tip and method of use
The invention provides surgical needles with a porous distal portion from which a liquid injectate will weep or ooze multidirectionally under injection pressure while the porous distal portion of...
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7252653 |
Liquid injection needle and liquid injection device
A liquid injection needle ( 10 ) includes a hollow needle part ( 2 ) for injecting a liquid ( 8 ) and a supporting part ( 3 ), to which the needle part ( 2 ) is fixed. The needle part ( 2 )...
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7250036 |
Intradermal syringe and needle assembly
A method for using a needle assembly for an intradermal injection, and a drug delivery device is provided, which includes a needle cannula and a limiter surrounding the needle cannula and includes...
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7244270 |
Systems and devices for soft tissue augmentation
Medical devices, systems and kits for filling tissue are disclosed. The device has a first configuration wherein the device can pass through a small catheter or needle placed in the tissue to be...
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7217263 |
Device and method for manual retinal vein catheterization
A microcatheter system that allows for vascular infusion into retinal veins for extended periods of time. The microcatheter system includes a flexible cannula that is inserted into the retinal vein...
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7211062 |
Solid solution perforator for drug delivery and other applications
A solid drug perforator (SSP) system and an associated drug reservoir are provided for delivering theraputic, prophylactic and/or cosmetic compounds, for nutrient delivery and for drug targeting....
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7204828 |
Collection needle
A needle structure having proximal and distal ends and including a collection needle section at a more proximal end of the needle structure and a skin plug retainer section at the very distal end...
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7182757 |
Medical guide wire
In a medical guide wire ( 1 ) formed by a helical hollow wire body which is arranged to retractably move against a needle tip ( 6 ), the helical hollow wire body is formed into a wire-stranded...
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7150735 |
Drug container entry mechanisms and method
The invention of this application relates generally to intravenous (IV) infusion of drugs to patients, and more particularly to aspects of an IV infusion system comprising an infusate cassette and...
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7127284 |
Electroporation microneedle and methods for its use
Electroporation of cells in target tissues is performed using microneedles having integral electrode structures. In a first embodiment, a pair of electrode structures are disposed on opposite sides...
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7108679 |
Intradermal syringe and needle assembly
A needle assembly for an intradermal injection device, and a drug delivery device, which includes a needle cannula and a limiter surrounding the needle cannula and includes a skin engaging surface...
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7103418 |
Active fluid delivery catheter
A medical system incorporating fluid delivery and lead delivery lumens dispense fluid into a volume of tissue. The fluid comprises or contains a pharmacologic, genetic, or biologic agent. The fluid...
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7097637 |
Safety needle with positive flush
A safety needle device and positive flush mechanism for use with a vascular access port. In one embodiment, the combination needle assembly includes a needle, a body and a base, the body being...
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7097631 |
Self-actuating applicator for microprojection array
An applicator for applying a microprojection member to the stratum corneum of a patient having a housing, a piston moveable within the housing and a cap adapted to activate the applicator. The...
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7087040 |
Apparatus for delivering ablation fluid to treat lesions
A surgical apparatus for delivering fluid to treat a lesion comprising a housing, an elongated member extending from the housing, and a plurality of tines positioned in the housing. Each of the...
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7077830 |
Medical syringe needle
A needle for medical use, which is free from breakage of a cannula even if subjected to reapeated bending operations or puncture into the root of teeth in use. The needle is charactrized in that a...
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7070583 |
Medical bevel needle
A medical bevel needle ( 1 ) having an open bevel end surface 3 is provided, wherein cutting edges ( 9 ) that linearly extend from the front end of the front-end portion ( 2 ) on the right and...
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7070582 |
Injection devices that provide reduced outflow of therapeutic agents and methods of delivering therapeutic agents
Injection devices are provided, which reduce potential outflow of therapeutic agents from an injection site. Devices are provided having at least a first lumen containing one or more therapeutic...
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7060056 |
Biocompatible pharmaceutical articles
Many conventional pharmaceutical articles contain seemingly inert components that come into contact with a pharmaceutically active material during use, which contact substantially reduces the...
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7048723 |
Surface micromachined microneedles
Surface micro-machined micro-needles ( 32 ) are formed as single needles ( 32 ) or in two-dimensional or three-dimensional micro-needle arrays ( 30 ). The micro-needles ( 32 ) are fabricated on a...
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7037296 |
Curved multi-purpose phacoemulsification needle
A multipurpose phacoemulsification needle includes a needle body having a lumen therethrough for aspiration of fluids and tissue. A needle body includes a proximal end adapted for attachment to a...
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7024749 |
Method for manufacturing a cannula assembly
The present invention is directed to a novel process for inserting a cannula, such as a hypodermic needle, into a hub member by roughening a first portion of the cannula while leaving a second...
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6980855 |
Microneedles for minimally invasive drug delivery
The present invention provides a microneedle incorporating a base that is broad relative to a height of the microneedle, to minimize breakage. The microneedle further includes a fluid channel and a...
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6979339 |
Medico-surgical instruments
The rear end of a dual lumen oocyte recovery needle is sealed in a plastics hub by means of two polyurethane seals compressed between the outside of the needle and opposite ends of a bore through...
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6960196 |
Detectable heavy duty needle
The present invention provides a detectable heavy duty needle cannula ( 12 ) for use in hypodermic syringes and the like. Needle cannula ( 12 ) comprises a magnetizable or magnetized stainless...
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6960193 |
Method and apparatus for the transdermal administration of a substance
A transdermal delivery device includes a plurality of microneedles for injecting a substance such as a pharmaceutical agent into or below the stratum corneum of the skin. The device has housing...
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6958056 |
Multi-purpose phacoemulsification needle
A multipurpose phacoemulsification needle includes a needle body having a lumen therethrough for aspiration of fluids and tissue. A needle body includes a proximal end adapted for attachment to a...
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