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7569029 |
Multi-lumen catheter
The invention provides a catheter for placement within a vessel of a patient. The catheter comprises an elongated catheter body, a septum extending longitudinally through the interior of the...
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7393501 |
Method, apparatus and system for treating biofilms associated with catheters
An apparatus, system and method for preventing or treating biofilm associated with catheters. A piezo-ceramic element may be attached to a catheter, and a vibration processor may be connected to...
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7223226 |
Brachytherapy needle and methods for assembling same
Needles and methods of plugging a needle having a tip opening with an inside diameter and a needle tip length, wherein the methods generally comprise the steps of, providing a plug material having...
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7182758 |
Apparatus and method for drainage
An apparatus for drainage of a wound or surgical site of a human or animal fits anatomically, passes from inside the wound or surgical site percutaneously or covering an open wound surface and...
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7125402 |
Surgical drain
An improved surgical drain tube 10 having an internal passageway 12 , a plurality of portions 14 of the external wall of the tube extending outwardly and being arranged in opposing pairs, the...
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7108674 |
Catheter
A catheter comprising a dual lumen tube with a bolus at its distal end having a bullet nose. A venous port is formed in one side of the bolus adjacent the bullet nose of the bolus. An arterial port...
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7071235 |
Latent reactive blood compatible agents
A reagent and related method for use in passivating a biomaterial surface, the reagent including a latent reactive group and a bifunctional aliphatic acid (e.g., fatty acid), in combination with a...
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6979317 |
Device for delivering non-biodegradable bulking composition to a urological site
A device for delivery of a biocompatible polymer composition for treatment of urinary incontinence provides for delivery of biocompatible polymer material and a solidification agent through two...
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6908455 |
Surgical suction probe system with an easily cleaned internal filter
A suction probe system for cleaning debris from a surgical site includes a probe tip, a cylindrical filter with inner and outer chambers in fluid communication with the probe tip, and a suction...
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6852097 |
Mechanically active infusion catheter
A device and method to dissolve or eliminate blood clots from a patient relies upon a non-rapid moving mechanism to physically dissolve clots without damaging endothelium of the arteries and veins...
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6830556 |
Debridement extension providing irrigation and mechanical scrubbing for removal of dead, devitalized, or contaminated tissue from a wound
A debridement extension including a proximal end and a distal end, with the proximal end being adapted for connection to both an irrigation source and a suction source. The debridement extension...
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6733480 |
Declogging multilumen discharge assembly
A multilumen discharge assembly for delivering mixed biological adhesives is provided, which comprises a base portion including a flow path to provide mixed biological adhesives therethrough, and...
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6730120 |
Medical device for delivering a therapeutic substance and method therefor
A device useful for localized delivery of a therapeutic material is provided. The device includes a structure including a porous material; and a water-insoluble salt of a therapeutic material...
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6723121 |
Polycarbonate-polyurethane dispersions for thrombo-resistant coatings
A coating for a medical device is described which enhances the bio-activity of the surface of a medical device, rendering the surface substantially bio-compatible. The bio-compatible coating is...
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6656217 |
Medical device coated with a polymer containing a nitric oxide releasing organometallic nitrosyl compound useful for the prevention of platelet aggregation
The aggregation of platelets on the surface of a foreign body exposed to the flowing blood of a living being (such as plastic tubing, a balloon or the end of a catheter surgically inserted in a...
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6630580 |
Silyl and Heparin compositions
The present invention provides an anti-thrombogenic and cellular-adhesion coating composition for blood-contacting surfaces. The coating comprises a covalent complex of from 1 to 30 hydrophobic...
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6626874 |
Anticoagulant internally coated needle
To prevent blood from clotting or being diluted (which causes inaccuracy in the measurement of the characteristics of blood drawn from a patient), a needle assembly has the interior portion of its...
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6596699 |
Nucleic acid coating compositions and methods
A nucleic acid coating composition including a polyanion bound, directly or through one or more intermediates, to a medical device surface, with a condensate comprising a polycation and nucleic...
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6517531 |
Medical suction device
A medical device for fragmenting objects and aspirating remaining debris enables a physician or other medical personnel quickly and easily remove objects, such as kidney stones, from a patient. The...
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6348042 |
Bioactive shunt
The present invention relates to a shunt, and a method for treating catheters, more particularly shunts, wherein the catheter is made of a biocompatible material and adapted at least for insertion...
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6342591 |
Amphipathic coating for modulating cellular adhesion composition and methods
The present invention provides an anti-thrombogenic and cellular-adhesion coating composition for blood-contacting surfaces. The coating comprises a covalent complex of from 1 to 30 hydrophobic...
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6293927 |
Stationary central tunnel dialysis catheter with optional separable sheath
A stationary central dialysis catheter having a planar axially elongated sinuous tubular member having a plurality of axially extending lumens therein and at least a part having a predetermined...
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6273875 |
Medical devices having improved antimicrobial/antithrombogenic properties
An enhanced antimicrobial antithrombogenic medical device is formed by using an oligodynamic metal and a noble metal with a polymer, and forming the mixture into a device. By using low...
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6197051 |
Polycarbonate-polyurethane dispersions for thromobo-resistant coatings
A medical device is described which has on a surface thereof a bio-compatible coating. This bio-compatible coating is formed from a composition which includes an aqueous emulsion or dispersion of a...
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6193752 |
Urological implant, in particular vascular wall support for the urinary tract
A urological implant, in particular a vascular wall support for the urinary tract, is provided with a substantially tubular, inherently stable carrier, a spacer film bonded to the carrier...
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6033393 |
Method and apparatus for overpressure protection of a catheter
A method and apparatus for overpressure protection of a catheter from an indwelling catheter. A method in one embodiment includes injecting an agent into the catheter and relieving overpressures in...
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5955588 |
Non-thrombogenic coating composition and methods for using same
The present invention provides an anti-thrombogenic coating composition for blood-contacting surfaces. The coating comprises a covalent complex of from 1 to 30 hydrophobic silyl moieties of Formula...
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5897534 |
Body fluids and solids drainage system
A medical system for facilitating the removal of body matter including solids, liquids and gases from a body cavity. The system includes mechanical energy applied to the interior surface of a...
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5871692 |
Method and apparatus for cleaning, decontaminating, and sterilizing catheters
A method for cleaning, decontaminating, and sterilizing catheters (10) using a combination of liquid and gaseous/plasma sterilization techniques to ensure the complete and efficient sterilization...
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5868720 |
Indwelling catheter with stable enzyme coating
An improved indwelling catheter adapted for long-term usage includes a stable enzyme coating to prevent occlusion of the catheter lumen. The enzyme coating includes a fibrinolytic and/or lipolytic...
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5821235 |
Gene therapy using the intestine
Method for in vivo introduction of a nucleic acid cassette into stem cells of intestinal epithelium. The nucleic acid cassette is introduced via vector solution. The vector solution can be...
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5814025 |
Self-venting fluid system
A system and method is provided which substantially eliminates the effect of air entrapped in tubing for delivering a liquid from a container. The inner diameter of the tubing is selected such that...
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5800412 |
Hydrophilic coatings with hydrating agents
According to the invention, hydrating agents in ultrafine form may be incorporated in an organic coating solution with a uniform distribution that does not change due to settling. In preferred...
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5797887 |
Medical device with a surface adapted for exposure to a blood stream which is coated with a polymer containing a nitrosyl-containing organo-metallic compound which releases nitric oxide from the coating to mediate platelet aggregation
A surface of a foreign body exposed to the flowing blood of a living being which normally would promote the aggregation of platelets in that blood to form a layer affixed to that surface and thus...
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5762944 |
Antithrombotic resin, antithrombotic tube, antithrombotic film and antithrombotic coat
The invention presents an antithrombotic resin which is prepared by blending at least one type of antithrombotics, in polyurethane or polyurethane urea polymerized by using at least one type of...
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5760130 |
Aminosilane/carbodiimide coupling of DNA to glass substrate
A method for coupling DNA to a glass substrate by aminating the glass substrate with an aminosilane, reacting DNA with a carbodiimide/imidazole solution to create a 5'-phosphorimidazolide, and...
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5731087 |
Lubricious coatings containing polymers with vinyl and carboxylic acid moieties
Lubricious coatings comprising a binder polymer having a vinyl moiety and a carboxylic acid moiety and a hydrophilic polymer are disclosed. The coatings can be applied to a variety of substrates...
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5728751 |
Bonding bio-active materials to substrate surfaces
A medical device having a bio-active coating is prepared by providing a polymeric substrate having hydroxyl and/or amine functionality on a surface thereof and applying the bio-active coating to...
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5728437 |
Articles exhibiting a blood-compatible surface layer and process for providing articles with such a surface layer
Article exhibiting at least one surface of glass, metal or hydrophobic polymer coated with blood-compatible surface layer, in which the biocompatible surface layer consists of an adsorbed...
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5686409 |
Antirestenosis protein
A method of treating primary and recurrent atheromatous plaque development is provided. The method involves administering a therapeutically effective amount of SERP-1, admixed in a pharmaceutically...
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5679659 |
Method for making heparinized biomaterials
An improved method of making a medical device having immobilized heparin on a blood-contacting surface in which heparin is admixed with sufficient periodate to react with not more than two sugar...
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5668193 |
Solid substrate coated with an aminopolysaccharide
A solid substrate, the surface of which has been modified to introduce reactive groups of a hydrophilic nature thereon, the modification being provided by a primer comprising a first polysaccharide...
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5665077 |
Nitric oxide-releasing nitroso compositions and methods and intravascular devices for using them to prevent restenosis
A surface of a foreign body exposed to the flowing blood of a living being which normally would promote the aggregation of platelets in that blood to form a coating firmly affixed to that surface...
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5628306 |
Respiratory manifold with accessory access port
A ventilator manifold is disclosed which includes a port for attachment and detachment of an accessory device thereto without interruption of continuous respiratory support of the patient. A...
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5591140 |
Radiofrequency plasma treated polymeric surfaces having immobilized anti-thrombogenic agents
Polymeric surfaces of medical devices or components of medical devices are provided that have enhanced biocompatibility properties. The polymeric surface presents an anti-thrombogenic, fibrinolytic...
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5569463 |
Medical device polymer
A medical device and a method for its manufacture. The function of the medical device requires exposure of the device to the tissue of a patient. The device has a tissue-exposed portion constructed...
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5562922 |
Drug incorporating and release polymeric coating for bioprosthesis
In accordance with the present invention, there are provided prosthetic articles having polyurethane coatings with biologically active compounds incorporated within the interstices of the polymer....
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5562610 |
Needle for ultrasonic surgical probe
A hollow operating needle for an ultrasonic surgical probe for fragmenting and removing material from the body has an elongated tapered portion which is coupled at its larger end portion to an...
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5545213 |
Method for administering a bioactive agent
Articles having a graft polymer with a net ionic charge bonded to a polymeric substrate surface provide an improved method for administering a bioactive agent having a net ionic charge. The...
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5509932 |
Fixed tissue medical devices comprising albumin-binding dyes
An implantable medical device is provided which comprises a fixed tissue incorporating an amount of an albumin-binding dye effective to form a coating of endogenous albumin on said device when the...
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