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7616989 |
Manufacturing methods for an apparatus for the controllable modification of compound concentration in a tube
Apparatus and methods for delivery of a drug or compound into a fluid flowing within a tube or catheter. In one embodiment a catheter includes an inner surface coated with a polymer matrix such as...
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7608064 |
Depth probe for intracranial treatment
A depth probe for intracranial treatment is provided having a body that includes a distal portion with one aperture and at least one element mounted upon the exterior surface, a lumen defined by...
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7596407 |
Transdermal iontophoretic delivery of piperazinyl-2(3H)-benzoxazolone compounds
The invention is related to an iontophoretic method for the delivery of a compound of the formula
wherein R is defined herein, and pharmaceutically acceptable salts and prodrugs thereof;...
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7593770 |
Method and device for enhanced delivery of a biologically active agent through the spinal spaces into the central nervous system of a mammal
A delivery method and implantable apparatus that allows for controlled, enhanced and (pre)-programmable administration of a biologically active agent into the spinal structures and/or the brain via...
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7590444 |
Iontophoresis device
An iontophoresis device for administering drug ions via the first ion-exchange membrane, comprising a first semi-permeable film having a number of pores passing through the film from a front...
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7588551 |
Hemodialysis access with on-off functionality
A treatment assembly is positioned along an AV-fistula and couples therapeutic energy to an adjacent area due to a material response to an applied energy field from a remotely located energy...
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7574256 |
Iontophoretic device and method of delivery of active agents to biological interface
An iontophoresis device includes: an active electrode element operable to provide an electrical potential; an inner active agent reservoir comprising: a first compartment having a diluent; a second...
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7558625 |
Combined micro-channel generation and iontophoresis for transdermal delivery of pharmaceutical agents
The present invention relates to methods of transdermal delivery of pharmaceutical agents. In particular, the present invention relates to a method for transdermal delivery by generating...
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7558624 |
Apparatus for reverse iontophoresis and method for reverse iontophoresis
An apparatus for reverse iontophoresis has a base, an electrode provided on the base, an electrolytic gel provided on the electrode adapted for contacting a first part of a specimen, and for...
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7555337 |
Method for non-invasively determining the relative levels of two biological substances
The method for non-invasively determining the relative levels of two substances present in a biological system includes the steps of extracting by reverse iontophoresis charged and uncharged...
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7536221 |
Coatings comprising self-assembled molecular structures
A coating for an implantable medical device is disclosed, the coating including a self-assembled molecular structure. The coating can be used for altering the release rate of a therapeutic...
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7534740 |
Method to produce photo-catalyst physical water molecule for medical purposes
A method to produce photo-catalyst physical water molecule for medical purposes includes the following steps: mixing aqua pura and TiO 2 at the ratio of 1:1 at a temperature range of 50 to 60° C....
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7532926 |
Method and apparatus for skin absorption enhancement and transdermal drug delivery
A removable component for a probe used to treat a patient's skin with a skin-treatment substance, include an attachment device having a plurality of holes for respectively accommodating a plurality...
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7526334 |
Electrochemical treatment of tissues, especially tumors
A technique and apparatus therefor adapted to treat in situ specified tissue, especially a malignant tumor, use being made of electrodes implanted in the tissue at spaced positions. Applied across...
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7524327 |
Light activated gene transduction using long wavelength ultraviolet light for cell targeted gene delivery
In accordance with the present invention, methods are provided for treating a patient through the use of ultraviolet light activated gene therapy. Embodiments of the present invention include...
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7522955 |
Method and apparatus for the ultrasonic cleaning of biofilm coated surfaces
To treat body surfaces, such as the sinuses, which are coated with biofilms, the surface is irrigated and suctioned with a fluid which may contain a biocide or other chemical agent for disrupting...
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7522954 |
Device for the transcutaneous administration of substances by means of iontophoresis
A device for the transcutaneous administration of substances by means of iontophoresis comprises an operative head ( 1 ) provided with an inlet ( 2 ) for a fluid transporting substances to be...
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7519418 |
Mechanical apparatus and method for dilating and delivering a therapeutic agent to a site of treatment
An apparatus for delivering a medicament, such as a liposome or micelle-encapsulated therapeutic agent or medicament, to an obstruction within a vascular segment or a body passageway. The apparatus...
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7517342 |
Polymer coated device for electrically medicated drug delivery
The present invention relates to a catheter with an expandable distal end for delivering one or more medicaments. The catheter is manufactured with materials of construction that allow the transfer...
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7515957 |
Catheter-based, dual balloon photopolymerization system
A system for applying a polymer (hydrogel) to the inner surface of a vessel by photopolymerization includes a catheter having a first inflatable member and a guidewire having a second inflatable...
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7511031 |
Noninvasive vascular therapy
The present invention is drawn to apparatus for transcutaneous photodynamic therapy (“PDT”) of a target tissue or compositions in a mammalian subject, which includes a light source that is...
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7507228 |
Device containing a light emitting diode for treatment of barrier membranes
The present invention features a device having a barrier membrane contacting surface, the device containing: a power source; a first conductive electrode; a second conductive electrode; a first...
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7505812 |
Electrosurgical system for treating restenosis of body lumens
The present invention comprises apparatus and methods for maintaining patency in body passages subject to occlusion by invasive tissue growth. The apparatus and methods of the present invention may...
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7495146 |
Wound dressing
A wound dressing or bandage that provides a galvanic current for extended periods of time before having to change the dressing or bandage is addressed in the present invention. The present...
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7490049 |
Patient oriented point of care system and method
Computer-assisted methods, systems and mediums for providing, to a physician, information relating to a patient. One embodiment of the present invention is a method that comprises the steps of...
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7486989 |
Device for delivery of oxidizing agents to barrier membranes
The present invention features a method of treating infection in a barrier membrane by applying to the membrane a device having a barrier membrane contacting surface that administers an oxidizing...
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7483738 |
Combination stimulating and exothermic heating device and method of use thereof
The present invention is of an apparatus and method for enhancing skin, muscle and nerve stimulation and controlled delivery of an active substance to a subject's skin. Moreover, the present...
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7483737 |
Electrode chip for biological application and its using method
This invention relates to a technology for preventing leakage of liquid from gel ( 70 ). The electrode chip ( 10 ) comprises a cup-like support ( 20 ) including a cup part ( 210 ), and a sheet-like...
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7483736 |
Feedback control device for transcutaneous drug delivery and uses therefor
Provided herein is a device for altering a biological membrane in an individual comprising a means for delivering energy to the surface of said biological membrane; a means for monitoring a...
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7480530 |
Device for treatment of barrier membranes
The present invention features a device having a barrier membrane contacting surface, the device containing: a power source; a first conductive electrode; a second conductive electrode; and a...
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7479133 |
Methods of treating acne and rosacea with galvanic generated electricity
The present invention features a method of treating acne or rosacea on the skin by applying electricity to skin in need of such treatment wherein said electricity is generated by a first conductive...
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7479132 |
Patch material for ionic medicine administration
The present invention discloses a patch for use in administration of an ionic medicine into a living body by infiltration of the ionic medicine into the living body through the living body surface...
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7477941 |
Methods of exfoliating the skin with electricity
The present invention features a method of exfoliating the skin by applying to skin in need of such exfoliating a device including a housing having a skin contacting surface, a first conductive...
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7477940 |
Methods of administering an active agent to a human barrier membrane with galvanic generated electricity
The present invention features a method of administering an active agent to a human barrier membrane by applying to the membrane a device including a housing having the barrier membrane contacting...
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7477939 |
Methods of treating a wound with galvanic generated electricity
The present invention features a method of treating a wound by applying electricity to a barrier membrane in need of such treatment wherein said electricity is generated by a first conductive...
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7477938 |
Device for delivery of active agents to barrier membranes
The present invention features a device having a barrier membrane contacting surface, the device containing: a power source; a first conductive electrode; a second conductive electrode; and a...
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7476222 |
Methods of reducing the appearance of pigmentation with galvanic generated electricity
The present invention features a method of reducing the appearance of pigmentation on the skin by applying electricity to skin in need of such treatment wherein said electricity is generated by a...
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7476221 |
Methods of treating acne and rosacea with electrochemically generated zinc ions
The present invention features a method of treating acne or rosacea by applying to the skin electrochemically generated zinc ions. In one embodiment, the method includes topically applying a device...
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7474919 |
Laser-based method and system for enhancing optical breakdown
An additive, preferably in the form of metal nanoparticles or nanodomains, greatly improves a laser-based method and system for inducing optical breakdown. The use of ultrashort laser pulses to...
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7460914 |
Devices and methods to stimulate therapeutic angiogenesis for ischemia and heart failure
A method for stimulating angiogenesis is provided that includes the use of an electrical output channel adapted to deliver a sub-threshold voltage, a lead that includes a proximal end adapted to be...
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7458982 |
Photokinetic delivery of biologically active substances using pulsed incoherent light
The invention relates generally to transdermal and transmembrane delivery of biologically active substances through the skin, sub-dermal tissues, blood vessels and cellular membranes without...
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7457667 |
Current producing surface for a wound dressing
In an embodiment, an article includes a primary surface, and a pattern of spaced dissimilar materials, on the primary surface. The pattern is to spontaneously produce electrical surface currents...
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7457661 |
Catheter-based, dual coil photopolymerization system
A system for applying a polymer (hydrogel) to the inner surface of a vessel by photopolymerization includes an inner catheter received within an outer catheter and a fluid channeling structure...
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7440798 |
Substance delivery system
A system being suitable for being secured substantially adjacent to a surface of a subject so as to effect delivery of at least one substance through the surface and into the subject. The system...
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7428435 |
Medical instrument for transdermally administering ionic medicine
A medical instrument for transdermally administering a medicine, in which an ionic medicine or an ionic medicine-containing substance is sealed in a bag made of an ion-exchange membrane. The...
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7427657 |
Aromatic sulfenates for type 1 phototherapy
The present invention discloses novel sulfenate derivatives and their bioconjugates for phototherapy of tumors and other lesions. The sulfenates of the present invention are designed to absorb...
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7424199 |
Fiber tip fluid output device
A fiber tip fluid output device is provided for holding a fiber tip in an electromagnetic energy cutting apparatus and for directing water particles over a radiation delivery end of the fiber tip....
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7415306 |
Transdermal delivery system for anti-emetic medication
The present invention provides a transdermal delivery system for hydrophilic anti-emetic agents and methods of using thereof. The system includes an anti-emetic hydrophilic adhesive composition of...
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7415302 |
Method and system for leading macromolecule substances into living target cells
A method and system for leading macromolecule substances into target cells includes an image picking unit, an image merging unit, an injection unit, and an energy conversion module. The image...
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7404815 |
Tissue ablation by shear force for sampling biological fluids and delivering active agents
The present invention relates to a method and a device for transporting a molecule through a mammalian barrier membrane of at least one layer of cells comprising the steps of: ablating said...
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