|
Match
|
Document |
Document Title |
|
|
5725817 |
Iontophoretic structure for medical devices
An iontophoretic structure for medical devices is provided that uses controlled electrical current derived from two dissimilar galvanic materials to drive oligodynamic metal ions into solution to...
|
|
|
5720710 |
Remedial ultrasonic wave generating apparatus
A remedial ultrasonic wave generating apparatus which allows highly efficient dispensation of a medicine without complicated preparations is provided. An ultrasonic wave generating apparatus for...
|
|
|
5718913 |
Reservoir which can be impregnated with a solution of active principle, for an iontophoretic device for transdermal delivery of medicinal products and method of manufacture of such a resevoir
The reservoir loaded with a divided material which can be impregnated with the solution of active principle, comprises a) a support sheet (1) made of a cavitied material which is permeable to the...
|
|
|
5713845 |
Laser assisted drug delivery
The present invention provides a process for laser assisted drug delivery through the skin. A drug and a explosive absorber of light energy are applied topically to the skin. The treated area of...
|
|
|
5713846 |
Iontophoretic drug delivery system, including method for activating same for attachment to patient
An iontophoretic drug delivery system including a patch, a controller and a magazine. The patch may be secured in a compartment formed in the magazine so that upon insertion of the controller along...
|
|
|
5711761 |
Iontophoretic drug delivery
Improved methods of ionophoretic drug delivery are described. By the intentional selection of drug(s) with specific characteristics, of ionotophoresis device, components or both permits the...
|
|
|
5709653 |
Photodynamic therapy balloon catheter with microporous membrane
A photodynamic therapy balloon catheter with microporous membrane is provided which has an elongated optical fiber, an inner tubular member, a porous balloon member surrounding the inner tubular...
|
|
|
5710148 |
Corneal opacification inhibitory composition
An ophthalmic preparation which comprises a fumagillol derivative represented by the general formula(I): ##STR1## wherein R 1 is hydrogen; R 2 is a halogen, N(O) m R 5 R 6 , N + R 5 R 6 R 7 ...
|
|
|
5709676 |
Synergistic treatment of stenosed blood vessels using shock waves and dissolving medication
A method for removing a thrombus or plaque deposit from the wall of a blood vessel of a patient is enhanced by synergistic action of two individual procedures. A catheter is introduced into a blood...
|
|
|
5702359 |
Needle electrodes for mediated delivery of drugs and genes
An electrode apparatus for the application of electroporation to a portion of the body of a patient, comprises a support member, a pair of electrodes adjustably mounted on the support member for...
|
|
|
5700481 |
Transdermal drug delivery process
A calcitonin, its derivative or a salt thereof is transdermally delivered by iontophoresis in which a substantially constant voltage in the range of 3 to 20 V is applied at an electric current of...
|
|
|
5700243 |
Balloon perfusion catheter
The present invention is an improved balloon-type catheter with an integral fiber optic assembly for delivering light to a intraluminal target wherein the improvement comprises the use of a...
|
|
|
5698189 |
Method for local application of polymeric material to tissue
This invention relates to devices and techniques for applying therapeutic polymeric material to living tissue.
|
|
|
5698866 |
Uniform illuminator for phototherapy
A light delivery device including an interchangeable handpiece and a semiconductor light source module adapted to releasably attach to the handpiece. The light source module includes a...
|
|
|
5695482 |
UV treated catheter
A unitary, flexible, substantially noncollapsible catheter tube of biocompatible material is comprised of hard and soft regions. The hard regions can be ring shaped or helical. The hard regions...
|
|
|
5695459 |
Iontophoresis system
The present invention relates to an iontophoresis system. A power supply circuit for applying pulsating voltages to iontophoretic elements includes an element selector and a potential difference...
|
|
|
5688231 |
Iontophoresis assembly including cleanable electrical contacts
An iontophoretic delivery system permits transcutaneous delivery of a drug contained on a patch. The system includes a flexible planar patch having a medicament-containing surface in contact with...
|
|
|
5688233 |
Electronincorporation enhanced transdermal delivery of molecules
A method of transdermal molecular delivery comprising molecules to be delivered mixed with particles, contacting a selected area of a skin surface with the particles and molecules, applying a...
|
|
|
5685837 |
Galvanically active transdermal therapeutic system
A transdermal therapeutic system which is composed of layers exhibits an electrically insulating backing layer (1) being impermeable to active substances, and two galvanic elements which are...
|
|
|
5683381 |
In-line microwave warming apparatus
A microwave apparatus for warming of a liquid such as blood or IV fluids in which the warming occurs in-line by means of a microwave heating cavity having a source of microwave energy coupled...
|
|
|
5676648 |
Iontophoretic drug delivery apparatus and method for use
A portable iontophoresis apparatus for facilitating delivery of medication across the cutaneous membrane into adjacent underlying tissues and blood vessels. The apparatus employs a modular,...
|
|
|
5676646 |
Flow through electroporation apparatus
A flow through apparatus for implanting molecules into living blood cells of a patient, comprises a housing including an elongated flow through chamber having an inlet and an outlet at opposite...
|
|
|
5671317 |
Fiber optic positioner
Method and apparatus for stabilizing a fiber optic relative to the skin surface of a patient so that radiation from the fiber optic strikes a defined surface area on the skin independently of...
|
|
|
5667487 |
Ionosonic drug delivery apparatus
An improved apparatus for the iontophoretic-ultrasonic (ionosonic) transdermal delivery of medication across the skin or other biological membrane so the medication can be absorbed by the adjacent...
|
|
|
5667491 |
Method for rapid temporal control of molecular transport across tissue
A method is disclosed for treating tissue in response to a stimulus generated by the tissue. In one embodiment, the method transdermally treats an organism in response to a stimulus. In this...
|
|
|
5668170 |
Composition and method enhancing transdermal electrotransport agent delivery
A composition comprises an agent to be delivered through a body surface and an electrotransport enhancer having a hydrophobic tail and a polar head of specific characteristics. An electrotransport...
|
|
|
5660178 |
Hydrophilic pressure sensitive adhesives
A hydrophilic, pressure sensitive adhesive of a poly(ethylene oxide) derived network plasticized with an essentially non-volatile, polar plasticizer present in an amount sufficient to form a...
|
|
|
5658879 |
Enhancement of antitumor therapy with hemoglobin-based conjugates
The use of hemoglobin-polymer conjugates to enhance antitumor therapy in mammals is disclosed. The methods include administering an effective amount of an antitumor therapy such as radiation in...
|
|
|
5645527 |
Hydration assembly for hydrating a bioelectrode element
The present invention provides methods and apparatus permitting rapid and thorough hydration of an initially dry hydratable matrix element contained within a bioelectrode element for use in an...
|
|
|
5645526 |
Apparatus and method for ensuring compatibility of a reusable iontophoretic controller with an iontophoretic patch
An iontophoretic drug delivery device including a reusable controller and patch are disclosed. The controller and patch include electronics which ensure compatibility of the reusable iontophoretic...
|
|
|
5637084 |
Electrochemical method and device for drug delivery
An iontophoretic method for drug delivery may be powered by producing the necessary electropotential to deliver the drug using a difference in concentration of a salt across an anion selective...
|
|
|
5637085 |
Method of cancer tumor treatment by slow release delivery of 1,2,4-benzotriazine oxides to tumor site
Disclosed are a method and composition for intralesional therapy of solid cancer tumors, and especially brain tumors, comprising, delivering a compound of a 1,2,4-benzotriazine oxide contained in a...
|
|
|
5637749 |
Aryl imidate activated polyalkylene oxides
Water-soluble aryl imidate activated polyalkylene oxides having improved hydrolytic stability and conjugates of the aryl imidate activated polyalkylene oxides with biologically active nucleophiles...
|
|
|
5634895 |
Apparatus and method for transpericardial delivery of fluid
Method and apparatus for treating blood vessels in a mammal, particularly humans, especially coronary blood vessels, for vascular thrombosis and angioplasty restenosis, thereby to decrease...
|
|
|
5630793 |
Aqueous ophthalmic sprays
A method of administering to the eye a liquid ophthalmic formulation, comprising an ophthalmologically acceptable liquid and optionally containing an ophthalmologically-active substance,...
|
|
|
5630804 |
Metallic silver-plated silicon ring element for exit site disinfection and a method for preventing contamination at an exit site
A ring element (10) attaches to a length of tubing (12) to prevent contamination at a site (24) through which a portion of the length of tubing (12) extends. A resilient material having a first end...
|
|
|
5628729 |
Interface for iontophoresis with hydrating mechanism
An interface composed of an aqueous solution supply portion capable of providing a fine hole for supplying an aqueous solution, a water-permeable electrode, and a water-absorbable or...
|
|
|
5628727 |
Extracorporeal virioncidal apparatus
An extracorporeal radiation-therapy apparatus for use in treating the blood of a donor for diseased cells or organisms. The apparatus separates the blood by a density gradient device and treats the...
|
|
|
5627353 |
Spheres containing active compounds, their synthesis and the method of opening the spheres
Spheres with a tetrahedral, octahedral and icosohedral geometry containing active compounds, wherein the spheres embrace the same volume as the fullerenes of the same symmetry, and are described by...
|
|
|
5626617 |
Methods for treating disorders by administering radio frequency signals corresponding to growth factors
The present invention comprises homeopathic dilutions of growth factors and methods for their use. Disorders which may be effectively treated with the compositions of the present invention include...
|
|
|
5624415 |
Reduction of skin irritation and resistance during electrotransport
An electrotransport delivery device utilizing reservoir buffering at a select pH ranges in order to reduce skin irritation and skin resistance is provided. Cathodic reservoirs are buffered to a pH...
|
|
|
5624908 |
Antineoplastic compositions
Anti-cancer compositions containing chiral monosaccharides and methods of their use are disclosed herein. The compositions, exhibiting cytostatic and cytotoxic properties with regard to neoplastic...
|
|
|
5622944 |
Testosterone prodrugs for improved drug delivery
Compositions and methods are provided for enhanced transdermal electrotransport of 17-hydroxy sterol compounds, including testosterone. The parent sterols are modified at the 17-hydroxy position by...
|
|
|
5620580 |
Iontophoresis device
To avoid a reduction of the conductivity in iontophoresis due to the electrical decomposition and the changes in chemical properties of the electrodes themselves, covering by an electrical...
|
|
|
5621780 |
X-ray apparatus for applying a predetermined flux to an interior surface of a body cavity
The present invention is directed to an x-ray source for irradiating a surface defining a body cavity in accordance with a predetermined dose distribution. The source comprises a housing, an...
|
|
|
5620416 |
Methods of using topical agents with systemically administered active agents
The present invention relates to the simultaneous administration of topical agents and systemic active agents to treat diseases of the skin and surrounding tissues, wherein the topical drug is...
|
|
|
5618265 |
Iontophoretic delivery device with single lamina electrode
An electrically powered transdermal iontophoretic delivery device (10, 20) and a method of making same is provided. The device utilizes electrode assemblies (8, 9 ) composed of a substantially...
|
|
|
5618275 |
Ultrasonic method and apparatus for cosmetic and dermatological applications
Low frequency ultrasonic pressure waves of high intensity are applied to the skin to cause cavitation. A therapeutic agent may be applied to the skin in a predetermined amount prior to the...
|
|
|
5607691 |
Compositions and methods for enhanced drug delivery
The present invention relates to methods of delivering pharmaceutical agents across membranes, including the skin layer or mucosal membranes of a patient. A pharmaceutical agent is covalently...
|
|
|
5607420 |
Surgical tool for use with a contact laser
The surgical tool is used in conjunction with a direct contact laser that is powered through a small diameter laser power tube. In one embodiment, the tool includes a bendable, rigid tube having a...
|