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7462442 |
Biocompatible microchip and a method for producing the same
The invention relates to a process for the production of biocompatible structures. For this purpose, a chemically amplified photoresist is applied to a substrate and is structured. The photoresist...
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7335376 |
Method for photodynamic therapy and applicator for carrying out said therapy
The present invention relates to medicine, more concretely to photodynamic therapy, and may be used in oncology and dermatology. A method is proposed for photodynamic therapy of pathological...
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7094418 |
Crosslinkable macromers
A crosslinkable macromer system and related methods of preparing the system and using the system in the form of a crosslinked matrix between a tissue site and an implant article such as a tissue...
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7011093 |
Microencapsulated fragrances and methods of coating microcapsules
Nasal dilators and strips, methods of their manufacture, and methods for improving the breathing of individuals are provided. The strips and dilators include an elongated substrate, with or without...
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6916909 |
Collagen peptides modified by grafting mercapto functions, method for the production thereof and uses thereof as biomaterials
The invention relates to novel collagen peptides that are modified by grafting free or substitued thiol functions carried by mercaptoamine radicals. The aim of the invention is to provide thiol...
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6790438 |
Cross-linked collagenic peptide for preventing post-surgical adhesions
The aim of the invention is to provide a modified collagen peptide for preventing post-operative adhesions that is non-toxic, economic, in addition to being easy to obtain, sterilize, manipulate...
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6582713 |
Compositions and methods for promoting wound healing
The present invention provides methods and compositions for promoting wound healing and reducing scar formation. In particular, the present invention provides cyanoacrylate polymer sealants...
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6326025 |
Tissue reactive adhesive compositions
The present invention is directed to a biocompatible tissue reactive composition comprising a functionalized polymer having tissue reactive substituents that are capable of forming covalent bonds...
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6198016 |
Wet skin adhesive article
The present invention provides an adhesive article that includes a backing substrate and a discontinuous adhesive layer disposed thereon, wherein the backing substrate comprises a fibrous web and...
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6150581 |
Chitosan/alginate anti-adhesion barrier
Chitosan/alginate post-surgical anti-adhesion barriers, methods of preventing post-surgical adhesions, and methods and devices for forming post-surgical anti-adhesion barriers are provided. An...
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6143946 |
Therapeutic mat
A therapeutic mat for application to a person includes a relatively elastic substrate of a predetermined size, a hydrogel substance connected to the elastic substrate, and a plurality of...
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6043407 |
Debridement pad
A debridement pad is provided having fibrinolysin enzyme, desoxyribonuclease enzyme and cellulosic material in the form of a lyophilized sponge-like pad. Placement of the pad over an open wound...
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6040251 |
Garments of barrier webs
The present invention includes novel barrier webs that have certain desirable physical qualities such as water resistance, increased durability, improved barrier qualities and the like. The present...
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5997895 |
Dural/meningeal repair product using collagen matrix
Dural substitutes are provided, which include collagen treated and/or prepared to be physiologically compatible and substantially free of active viruses and prions. Suitable forms for the dural...
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5957877 |
Methods for draping surgical sites using peripheral cyanoacrylate drapes
Disclosed are methods for draping a surgical site prior to surgery. Specifically, the methods of this invention involve the in situ formation of a cyanoacrylate polymeric drape on the skin surface...
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5856245 |
Articles of barrier webs
A barrier web comprising a fabric that has been treated with a curable shear thinned thixotropic polymer composition, the fabric being adapted to be substantially impermeable to liquids, permeable...
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5763579 |
Collagen derivatives, process for producing them and their application to the preparation of biomaterials
The present invention relates to a modified collagen which is soluble in water and/or in aprotic polar organic solvents and which comprises free or substituted thiol functional groups carried by...
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5735812 |
Water soluble wound dressing materials
The invention provides water soluble wound dressing materials comprising from 5% to 50% of an alginate ester of a C 1 -C 6 polyhydric alcohol; from 50% to 95% of a humectant consisting of one or...
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5681580 |
Patch-type device for iontophoretic transdermal delivery of insulin
The present invention is a patch-type device for iontophoretic transdermal medication of insulin of one-piece form having a container for holding gel-like insulin and a power supply for furnishing...
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5681579 |
Polymeric support wound dressing
In accordance with the present invention a novel wound dressing providing superior absorption and preventing leakage is disclosed. The present dressing comprises a hydrocolloid-containing polymeric...
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5662925 |
Transdermal delivery system with adhesive overlay and peel seal disc
A device for administering an active agent to the skin or mucosa of an individual comprising a laminated composite of an adhesive overlay, a backing layer underlying the central portion of the...
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5580923 |
Anti-adhesion films and compositions for medical use
Anti-adhesion films useful for the prevention of surgical adhesions are disclosed. These films comprise substrate materials (such as collagen) and hetero-bifunctional anti-adhesion binding agents,...
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5567806 |
Collagen crosslinked with a crosslinking agent for the manufacture of a suturable, biocompatible slowresorbing membrane, and such a membrane
Suturable, biocompatible, control-resorbing membranes are disclosed for use in guided tissue regeneration, comprising a cross-linked collagen material either obtained by crosslinking a starting...
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5496872 |
Adhesive compositions for surgical use
The invention relates to an adhesive, biocompatible, biodegradable and non-toxic composition for surgical use, in particular for binding tissues, which composition is of the following general...
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5462536 |
Protein nonadsorptive membranes for wound dressings
Controlled release membranes are prepared from polyureaurethane polymer derived from prepolymer units at least 75% of which are oxyethylene-based diols or polyols having essentially all of the...
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5420248 |
Unpigmented fish skin, particularly from flat fish, as a novel industrial source of collagen, extraction method, collagen and biomaterial thereby obtained
The present invention relates to the use of unpigmented skin from flat fish as novel industrial source of collagen. As unpigmented skin, the ventral skin is used in particular, from sole, dab,...
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5418222 |
Multi-layered collagen film compositions for delivery of proteins and methods of using same
The present invention relates to single and multiple layer collagen films that are useful for improved sustained release delivery of pharmaceuticals.
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5412076 |
Crosslinkable collagen derivatives, process for their production and their application to the preparation of biomaterials
The present invention relates to a crosslinkable modified collagen which is soluble in water and/or in aprotic polar organic solvents and which contains free or substituted thiol groups carried by...
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5201745 |
Visceral surgery patch
A patch for visceral surgery is made from a biomaterial consisting of two layers of collagen superimposed and closely combined, namely a porous adhesive layer of fibrous collagen and a film of...
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5149469 |
Method of manufacturing a wound dressing
A method of manufacturing a wound dressing having microscopic web-like interconnections and a porous structure of continuous pores throughout the wound dressing. In the first embodiment of the...
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5003970 |
Roll form medical bandaging product, method of constructing same and container for roll form bandaging product
An outer container (31) formed of moisture-impervious material having an elongate product dispensing sleeve (32) having a moisture-proof sealable opening (33) on one end and an enlarged product...
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4948540 |
Method of preparing collagen dressing sheet material
A mechanically stable, conformable collagen wound dressing sheet material is fabricated by lyophilizing (freeze-drying) a collagen composition and compressing the porous pad thus produced at a...
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4947840 |
Biodegradable templates for the regeneration of tissues
This invention relates to porous, biodegradable materials in which the pore size, biodegradation rate, and pore volume fraction are controlled and within values at which skin contraction rates...
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4841962 |
Collagen matrix/polymer film composite dressing
A wound dressing comprising a crosslinked collagen matrix; a bioabsorbable adhesive coated on one surface of the collagen matrix; a multilayer polymer film imparting pre-selected moisture vapor and...
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4837285 |
Collagen matrix beads for soft tissue repair
Collagen-based compositions for augmenting soft tissue, wound dressings, implants, injectable formulations or other drug delivery systems, comprising resorbable collagen matrix beads, the beads...
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4784653 |
Absorbent adhesive dressing
An absorbent adhesive dressing is disclosed which is intended for use in treating wounds of the ulcer and burn type where there is significant wound exudate, which has a three layer sandwich-type...
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4760131 |
Wound-healing composition
A soft tissue wound healing composition comprising an aqueous mixture of fibrillar collagen, heparin, and undegranulated platelets or platelet releasate. The composition is applied topically to the...
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4759354 |
Wound dressing
Novel wound dressings comprising the following essential elements, in order: a thin outer vapor-permeable layer; an absorbent adhesive layer for adhering the wound dressing to the skin and for...
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4755593 |
Novel biomaterial of cross-linked peritoneal tissue
A biomaterial suitable for use in medical devices which comprises peritoneal tissue, especially animal parietal peritoneum tissue, which has been chemically treated to crosslink the collagen in the...
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4738849 |
Composite medical articles for application to wounds and method for producing same
A composite medical article comprising a porous body, a first layer of a medicinal substance and a second layer of a medicinal substance. A method for forming a composite medical article comprising...
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4725671 |
Collagen membranes for medical use
Collagen membranes with desired properties are prepared by using a variety of gel-forming techniques in combination with methods for converting the gels to solid forms. The properties of these...
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4696812 |
Thrombin preparations
Thrombin solutions can be rendered storage stable using stabilizing quantities of an anti-autolytic buffer in combination with low levels of saline and glycerol to prevent denaturation.
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4683142 |
Resorptive sheet material for closing and healing wounds and method of making the same
A resorptive sheet material for closing and healing wounds substantially consists of a glycoprotein matrix containing substances which cause and, respectively, are conductive to the coagulation of...
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4668228 |
Debriding tape
Debriding tapes are disclosed which contain a proteolytic enzyme useful for debridement of eschar and necrotic tissue, e.g., subtilisin, bromelain, in dry powdered form on the adhesive mass surface...
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4655980 |
Process of making collagen membranes for medical use
A process for preparing collagen membranes useful in tissue repair, and wound healing and related membranous implant materials useful in both hard and soft tissue applications is disclosed. The...
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4655211 |
Hemostatic agent
A hemostatic agent and method for preparation thereof are described, said hemostatic agent comprising a carrier in the shape of flake or fiber having thrombin and Factor XIII fixed thereto, wherein...
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4621631 |
Process for the production of a bonded collagen fiber sheet
A process for the production of an unnative and biologically active bonded collagen fiber sheet from human placentae is described, in which process collagen-containing material from placentae is...
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4606910 |
Composite hemostatic article including a hemostatic agent onlay and methods for preparing the same
An improved hemostatic article is made by fusing an onlay of hemostatic agent to a porous body which is already impregnated with the same or with a different hemostatic agent. The hemostatic...
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4578067 |
Hemostatic-adhesive, collagen dressing for severed biological surfaces
Hemostatic-adhesive, collagen dressings in the form of dry-laid, non-woven, self-supporting webs of collagen fibers and methods for preparing those webs are disclosed. The webs are formed from a...
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4576817 |
Enzymatic bandages and pads
Enzymatic absorbent materials such as bandages and pads, for body contact applications, contain serum-activated oxidoreductase enzyme for producing hydrogen peroxide upon contact of the enzymatic...
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