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7610082 |
Optical system and method for in-vivo transcranial examination of brain tissue of a subject
An optical examination technique employs an optical system for in vivo non-invasive transcranial examination of brain tissue of a subject. The optical system includes an optical module arranged for...
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7610080 |
Method and device for determining tension in ligaments and tendons
Infrared and Raman spectroscopy methods are used to assess the tension of ligaments, tendons and other tissue. The device includes an electromagnetic radiation source for directing radiation energy...
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7596404 |
Method of chemical imaging to determine tissue margins during surgery
A method and system to differentiate a tissue margins during various medical procedures. A region containing a biological tissue is irradiated, with a substantially monochromatic light. Raman...
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7588535 |
Apparatus, method and system for intravascular photographic imaging
An apparatus, system and method for providing an image enhancing effect for a photographic image of a target region within an intravascular environment. The image enhancing effects may be a...
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7587236 |
Optical spectroscopy for the detection of ischemic tissue injury
An optical method and apparatus is utilized to quantify ischemic tissue and/or organ injury. Such a method and apparatus is non-invasive, non-traumatic, portable, and can make measurements in a...
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7553280 |
Implanted sensor processing system and method
A quantitative measurement system includes an external unit ( 101 a ) and an internal unit ( 102 a ) are provided for obtaining quantitative analyte measurements, such as within the body. In one...
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7535935 |
Spectroscopic catheter system with widely tunable source and method of operation
A laser system for a spectroscopic catheter system uses multiple semiconductor gain media having gain peaks at different wavelengths. The output from the gain media is preferably coupled into...
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7529577 |
Method and apparatus for locating foreign objects in the ear canal
The invention concerns a method for locating foreign objects on the internal surface of ear and ear canal whereby a probe having a light emitting distal portion is inserted into the ear canal, the...
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7519411 |
Method for elucidating reaction dynamics of photoreactive compounds from optical signals affected by an external magnetic field
A method elucidates reaction dynamics of photoreactive compounds from time-resolved optical signals affected by an external magnetic field. A coil or magnet applies a magnetic field at a region of...
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7515952 |
System for characterization and mapping of tissue lesions
The present invention provides a method and an apparatus for the in vivo, non-invasive, early detection of alterations and mapping of the grade of these alterations, caused in the biochemical...
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7505802 |
Capsule endoscope
A capsule endoscope is disclosed that includes a capsule and a transparent cover having a central axis and that is located in front of an objective optical system within the capsule. The objective...
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7495208 |
Portable optical wound scanner
In a wound scanning apparatus and method, a beam or sheet of light is scanned on a wound and reflections of the scanned beam or sheet of light interacting with the wound at a plurality of points...
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7486985 |
Near-infrared spectroscopic analysis of blood vessel walls
The invention relates to methods and devices for characterizing tissue in vivo, e.g., in walls of blood vessels, to determine whether the tissue is healthy or diseased.
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7426410 |
Spectroscopy of deeply-scattered light
A spectroscope includes first and second beam redirectors in optical communication with first and second fibers respectively. The first and second beam redirectors are oriented to illuminate...
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7359748 |
Apparatus for total immersion photography
Total Immersion Photography (TIP) is disclosed, preferably for the use of screening for various medical and cosmetic conditions. TIP, in a preferred embodiment, comprises an enclosed structure that...
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7336990 |
Equipment for subsurface autofluorescence spectroscopy
An equipment includes an excitation source ( 1 ), elements for injecting ( 2 ) an excitation signal produced by the source in an ordered bundle ( 3 ) of flexible optical fibers, elements for...
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7336989 |
System and method for quantitative or qualitative measurement of exogenous substances in tissue and other materials using laser-induced fluorescence spectroscopy
Methods and systems for determination of one or more substances within a material are described. A flow of fluorescence-exciting/ablative energy (e.g., laser pulse(s), preferably in the ultraviolet...
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7310547 |
Fluorescent fiberoptic probe for tissue health discrimination
A system and method for the in situ discrimination of healthy and diseased tissue. A fiberoptic based probe is employed to direct ultraviolet illumination onto a tissue specimen and to collect the...
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7302287 |
Methods of detecting inflammation of an epithelium layer in the oral region with a probe using diffuse-reflectance spectroscopy
The invention provides a device and method for monitoring inflammation of the epithelium. The device consists of a head region, a handle region and an optical bundle. At least two of the optical...
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7282723 |
Methods and apparatus for processing spectral data for use in tissue characterization
The invention provides methods for processing tissue-derived spectral data for use in a tissue classification algorithm. Methods of the invention comprise application of spectral and/or image masks...
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7280866 |
Non-invasive screening of skin diseases by visible/near-infrared spectroscopy
A non-invasive tool for skin disease diagnosis would be a useful clinical adjunct. The purpose of this study was to determine whether visible/near-infrared spectroscopy can be used to...
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7242832 |
Device for tissue characterization
A probe for use in characterizing tissue. The probe includes a plurality of optical fibers and an optical element. Each fiber includes a distal portion and a proximal portion. The fibers transmit...
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7236815 |
Method for probabilistically classifying tissue in vitro and in vivo using fluorescence spectroscopy
Fluorescence spectral data acquired from tissues in vivo or in vitro is processed in accordance with a multivariate statistical method to achieve the ability to probabilistically classify tissue in...
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7235045 |
Fluorescence imaging endoscope
An endoscope having an optical guide that is optically coupled to a first broadband light source and a second laser light source that emits light at a wavelength in a range of 350 nm to 420 nm. The...
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7231243 |
Optical methods for tissue analysis
The invention relates to methods and systems to optically analyze samples such as tissue based on speckle patterns of microscopic motion, such as Brownian motion.
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7197404 |
Computation of radiating particle and wave distributions using a generalized discrete field constructed from representative ray sets
The present system and method for simulating particles and waves is useful for calculations involving nuclear and full spectrum radiation transport, quantum particle transport, plasma transport and...
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7195923 |
Ratiometric determination of glycated protein
The present invention provides methods for determining a ratio of an amount of a glycated form of a protein to a total amount of the protein in a sample containing the glycated protein, the...
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7190991 |
Multi-mode internal imaging
The invention described herein provides systems and methods for multi-modal imaging with light and a second form of imaging. Light imaging involves the capture of low intensity light from a...
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7181265 |
Fluorescent image obtaining apparatus
A fluorescent image obtaining apparatus for obtaining as an image the data relating to the fluorescent light emitted from a measurement portion upon the irradiation thereof by an excitation light,...
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7167742 |
Utilization of an infrared probe to discriminate between materials
A method of evaluating the surface of a material that has a distinguishable infrared spectrum comprising (a) positioning an infrared fiber optic probe to be in contact with a surface of the sample...
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7151956 |
Imaging apparatus and an imaging head used therefor
An imaging apparatus in which an imaging head having an observation hole for intaking images of an object to be observed formed at a top end is exchangeably mounted to a main body having an imaging...
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7127282 |
Optical methods and systems for rapid screening of the cervix
A method and a system is provided for discriminating between healthy cervical tissue and pathologic cervical tissue based on the fluorescence response of the tissue to laser excitation (LIF) and...
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7113818 |
Apparatus for high resolution imaging of moving organs
Apparatus for high resolution imaging of a moving object comprises a source of low coherence light, an optical coherence tomography imaging instrument or a dual channel, optical coherence...
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7113817 |
Optical imaging of blood circulation velocities
New devices and methods are provided for noninvasive and noncontact real-time measurements of tissue blood velocity. The invention uses a digital imaging device such as a detector array that allows...
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7058441 |
Optical measuring system for diagnosing ear conditions
A system for detecting and diagnosing ear related conditions. The system includes a device capable of obtaining a spectrum of reflected light from an ear of a subject and a processing unit in...
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7054674 |
Method of and apparatus for investigating tissue histology
Apparatus for monitoring the presence of one or more chromophores in a tissue sample, comprises a light source for projecting light to illuminate an area of such tissue sample, a photo-receptor for...
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7039452 |
Method and apparatus for Raman imaging of macular pigments
A method and apparatus are provided for Raman imaging of carotenoids and related chemical substances in biological tissue, such as macular pigments. The method and apparatus utilize the technique...
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7016718 |
Medical laser apparatus and diagnostic/treatment apparatus using the medical laser apparatus
In photodynamic diagnosis and photodynamic therapy, the oscillating wavelength of laser light from a light source is fitted to a plurality of different kinds of photosensitizers and exciting...
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7013173 |
Optical probe with reference fiber
A system for characterizing tissue includes the steps of generating an emission signal, generating a reference signal, directing the emission signal to and from the tissue, directing the reference...
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6993376 |
Radiation measurement within the human body
A displacement difference dosimetry method is provided for use with in-vivo scintillating fiber radiation detectors. A scintillating fiber includes an insertion end which is incrementally inserted...
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6990369 |
Probe using diffuse-reflectance spectroscopy
The invention provides a device and method for monitoring inflammation of the epithelium. The device consists of a head region, a handle region and an optical bundle. At least two of the optical...
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6984828 |
Quantified fluorescence microscopy
The present invention relates to calibration apparatuses, methods or tools used in microscopy. A calibration tool for fluorescent microscopy includes a support, a solid surface layer including a...
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6984228 |
Phototherapy methods and systems
The invention features methods and systems for treating inflammatory, proliferative skin disorders, such as psoriasis, with ultraviolet phototherapy. The methods and systems use optical techniques...
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6975899 |
Multi-modal optical tissue diagnostic system
An apparatus and method according to the invention combine more than one optical modality (spectroscopic method), including but not limited to fluorescence, absorption, reflectance, polarization...
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6965793 |
Method for Raman chemical imaging of endogenous chemicals to reveal tissue lesion boundaries in tissue
Apparatus and methods for spatially resolved Raman detection of molecules indicative of the borders of lesions with normal tissue are disclosed. A region of biological tissue was illuminated with...
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6954667 |
Method for Raman chemical imaging and characterization of calcification in tissue
Apparatus and methods for spatially resolved Raman detection of calcification in tissues are disclosed. A region of soft non-arterial biological tissue is illuminated with monochromatic light. A...
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6932796 |
Liquid metering system
Systems and methods for measuring the flow of a liquid along a conduit are disclosed. A heat source applies thermal energy to a portion of a liquid flowing along a conduit thereby elevating its...
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6912412 |
System and methods of fluorescence, reflectance and light scattering spectroscopy for measuring tissue characteristics
The present invention utilizes a plurality of spectroscopic systems and methods to measure characteristics of tissue useful in the diagnosis of disease. In a preferred embodiment, a combination of...
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6895269 |
Device for controlling equipment by using signals from a living body
A device for controlling equipment includes at least one light projector adapted to project light onto a head of a living body. A light collecting section for collecting the light having passed...
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6766188 |
Tissue oxygen measurement system
A device and method in accordance with the invention for determining the oxygen partial pressure (PO 2 ) of a tissue by irradiating the tissue with optical radiation such that the light is emitted...
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