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7616987 |
Microprobe for 3D bio-imaging, method for fabricating the same and use thereof
A microprobe that is capable of using an incident and reflected radiation ray for three-dimensional (3-D) bio-imaging. The microprobe comprises a hollow body closed at one end and having an...
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7616986 |
Optical fiber scanner for performing multimodal optical imaging
An optical fiber scanner is used for multiphoton excitation imaging, optical coherence tomography, or for confocal imaging in which transverse scans are carried out at a plurality of successively...
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7616985 |
Method and apparatus for 3-D imaging of internal light sources
The present invention provides systems and methods for obtaining a three-dimensional (3D) representation of one or more light sources inside a sample, such as a mammal. Mammalian tissue is a turbid...
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7616984 |
Modification of the normalized difference method for real-time optical tomography
Computation-saving techniques and stability-adding techniques provide for fast, accurate reconstructions of a time series of images involving large-scale 3D problems, such as real-time image...
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7616321 |
Optical coupler for rotating catheter
An optical coupler for coupling to a rotating catheter has a housing with a rotatable distal face and a stationary proximal face. The distal face has an eccentric port and a central port. A lens is...
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7613505 |
Device for the detection and characterization of biological tissue
Method for detection and location of a difference in density and/or structure and/or chemical composition of a biological tissue ( 7 ) which is subjected to continuous illumination in a first...
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7613504 |
Spectroscopic cross-channel method and apparatus for improved optical measurements of tissue
According to the invention, a sampling system for spectroscopic measurements of a biological sample is disclosed. The sampling system includes a plurality of illumination points, a plurality of...
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7613503 |
Device with infusion holes for imaging inside a blood vessel
An imaging device such as a catheter has a plurality of infusion holes adapted to infuse liquid into the blood stream while substantially preventing radial jetting. An example imaging catheter...
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7610081 |
Method and device for generating an image using optical coherence tomography
The invention relates to a method for generating an image using optical coherence tomography, with a control device controlling the operation of an image generation device and a rinsing device...
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7610080 |
Method and device for determining tension in ligaments and tendons
Infrared and Raman spectroscopy methods are used to assess the tension of ligaments, tendons and other tissue. The device includes an electromagnetic radiation source for directing radiation energy...
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7610074 |
Multi-functional plasmon-resonant contrast agents for optical coherence tomography
A method of forming an image of a sample, comprising: forming an image of a mixture, by exposing the mixture to electromagnetic radiation; wherein the mixture comprises the sample and...
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7603167 |
Method and apparatus for 3-D imaging of internal light sources
The present invention provides systems and methods for obtaining a three-dimensional (3D) representation of one or more light sources inside a sample, such as a mammal. Mammalian tissue is a turbid...
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7603166 |
Method and apparatus for detection of vulnerable atherosclerotic plaque
Methods for the detection of inflammation associated with vulnerable atherosclerotic plaque to prevent heart attack and stroke are disclosed. The methods are also applicable to detection of...
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7603160 |
Intra-subject position display system
An intra-subject position display system for displaying a position of an intra-subject device, which is introduced into a subject and moves therein, wherein a relative position of the intra-subject...
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7603031 |
Programmable, multi-spectral, image-capture environment
A multi-flash photography system provides a dynamically-configurable lighting environment for a single exposure that is created and shaped through the sequentially firing of various light sources...
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7599732 |
Method and system for near-infrared fluorescence contrast-enhanced imaging with area illumination and area detection
According to one embodiment of the invention, a method for biomedical imaging includes directing time-varying excitation light at a surface area of a light scattering material, the material...
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7599731 |
Fluorescent light tomography
Described herein are systems and methods for obtaining a three-dimensional (3D) representation of the distribution of fluorescent probes inside a sample, such as a mammal. Using a) fluorescent...
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7598088 |
Optical imaging method and system for characterization and mapping of tissue lesions
The present invention provides a method and an apparatus for the in vivo, non-invasive, early detection of alterations and mapping of the grade of these alterations, caused in the biochemical...
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7596404 |
Method of chemical imaging to determine tissue margins during surgery
A method and system to differentiate a tissue margins during various medical procedures. A region containing a biological tissue is irradiated, with a substantially monochromatic light. Raman...
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7596403 |
System and method for determining path lengths through a body lumen
A system and method for determining the path length through a body lumen, for example to a specified location, is described. A location detection system may identify the location in space of an...
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7593763 |
Non-invasive in vivo measurement of macular carotenoids
A non-invasive in vivo method for assessing macular carotenoids includes performing Optical Coherence Tomography (OCT) on a retina of a subject. A spatial representation of carotenoid levels in the...
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7588535 |
Apparatus, method and system for intravascular photographic imaging
An apparatus, system and method for providing an image enhancing effect for a photographic image of a target region within an intravascular environment. The image enhancing effects may be a...
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7587236 |
Optical spectroscopy for the detection of ischemic tissue injury
An optical method and apparatus is utilized to quantify ischemic tissue and/or organ injury. Such a method and apparatus is non-invasive, non-traumatic, portable, and can make measurements in a...
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7583993 |
Fluorescence image display apparatus
A fluorescence image display apparatus is provided; wherein, when a pseudo color image representing the tissue state of a target subject is obtained, based on a fluorescence image emitted from the...
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7574253 |
Signal processing using non-linear regression with a sinusoidal model
A method for processing signals, such as a tomography signal, in the time domain provides both high spatial resolution and high frequency resolution but at low cost. The method uses non-linear...
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7570988 |
Method for extraction of optical properties from diffuse reflectance spectra
An iterative process calculates the absorption and scattering coefficients of tissue from a set of diffuse reflectance measurements made with an optical spectrometer operating in the UV-VIS...
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7570984 |
Diagnostic imaging apparatus
A diagnostic imaging apparatus of hand piece type suitable for medical or dental use, comprising a main body held by operator's fingers, a luminous means for irradiating at least one of lights...
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7570983 |
Method and data processing device to support diagnosis and/or therapy of a pathological change of a blood vessel
In a method to support the diagnosis and/or therapy of a pathological change of a blood vessel of a patient, in particular in the context of coronary heart disease at a first point in time of a...
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7567833 |
Enhanced illumination device and method
A light source illuminates a field of interest that includes an illumination module capable of projecting illumination light to the field of interest and a light projector associated with the...
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7565192 |
Biological optical measurement system
A typical task assigned for measuring a brain activity signal lasts from 10 to 30 seconds. The frequency band of the Mayer wave noise signal is very close to the frequency bands of brain activity...
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7561908 |
System and method for changing transmission from an in vivo sensing device
A device and system enables obtaining data such as in vivo images from within body lumens or cavities, such as images of the gastrointestinal (GI) tract. A device may include an imaging system and...
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7561733 |
Patient registration with video image assistance
A method and device for reciprocally assigning a spatial position of a patient and/or a part of a patient's body and an acquired, stored patient data set includes producing at least two video image...
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7558620 |
Capsule-type medical device
In order to realize a capsule-type medical device suitable for improving efficiency of wireless transmission/reception using an antenna to increase radiowave power, a capsule-type medical device is...
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7558619 |
Raman instrument for measuring weak signals in the presence of strong background fluorescence
A method for measuring a chemical concentration in tissue has two measurement steps. A portion of tissue is illuminated with a first generated light and a second generated light. A first Raman...
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7558618 |
Method for extracting images of vascular structure and blood flow from image sequences
Periodic biological functions and their related anatomy that cannot be seen in image sequences using typical means, can nonetheless be made visible by demodulating the image sequence according to...
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7558416 |
Apparatus and method for measuring photodamage to skin
An apparatus and method for assessing photodamage has a digital imaging system for recording blue light imagining and in particular the green signal response intensity of the skin of a person,...
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7555334 |
Small animal light intensity monitor
Disclosed are methods and apparatus for collecting light emitted from an animal, where a luminescent reporter has been injected into the animal is disclosed. The apparatus includes a chamber for...
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7555333 |
Integrated optical scanning image acquisition and display
An apparatus and method for providing image acquisition and/or image display in a limited region of interest (ROI). The apparatus comprises a micro electro-mechanical system (MEMS), preferably...
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7555332 |
Fluorescent light tomography
Described herein are systems and methods for obtaining a three-dimensional (3D) representation of the distribution of fluorescent probes inside a sample, such as a mammal. Using a) fluorescent...
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7554572 |
Image pickup apparatus for capturing spectral images of an object and observation system including the same
An image pickup apparatus has a construction in which a diffraction element is provided in an observation optical system. Zero-order light that is transmitted straight through the diffraction...
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7553280 |
Implanted sensor processing system and method
A quantitative measurement system includes an external unit ( 101 a ) and an internal unit ( 102 a ) are provided for obtaining quantitative analyte measurements, such as within the body. In one...
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7553276 |
Method and device for imaging body lumens
An in-vivo imaging device including a ballast that may for example orient such device in a known orientation relative to the gravitational force on such ballast. Such imaging device may, for...
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7551955 |
Device, system and method for image based size analysis
A device, system and method for calculating a size of an object using images acquired by a typically moving imager, for example in the gastrointestinal (GI) tract. A distance traveled by the moving...
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7548776 |
Method and system for performing fever triage
A method and a system are disclosed for performing fever triage. At first, a thermal image-detecting unit is used to detect a testee at a time-point and a position so as to form thermal image data....
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7546156 |
Method of indexing biological imaging data using a three-dimensional body representation
A system and method for managing imaging data related to a biological trait, including generating a three-dimensional representation of the external surface of the body a patient; obtaining the...
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7539531 |
Catheter device
Catheter device for insertion into a vessel of a human or animal body, comprising a guide catheter and, incorporated in same, an OCT catheter with an OCT imaging device, the guide catheter having a...
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7539530 |
Method and system for spectral examination of vascular walls through blood during cardiac motion
A method for improving the treatment and/or examination of vessel walls through fluid, such as blood, functions by identifying the points in time when the catheter is closest to the vessel wall or...
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7538326 |
Visible light and IR combined image camera with a laser pointer
Methods and apparatuses of registering on a camera display separate fields of view of a visible light camera module and an infrared camera module by focusing the IR camera module. The fields of...
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7536217 |
System for detecting position of capsule endoscope in subject
A system is for detecting a position of a device. The device is swallowed, passes through a subject, and includes a magnetic field generator generating a constant magnetic field. The system also...
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7536213 |
Reduction in scattering from a turbid medium by photo-bleaching
A method is proposed whereby photo-bleaching is used not only to change the absorption and fluorescence of a sample but is also employed to change its scattering characteristics. When the compounds...
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