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6454761 Laser surgery device and method  
Laser surgery is controlled by interferometry.
6442409 Diagnostic system and method using radiant energy and implants  
A system for testing for the existence of a biomedical condition of an animal test subject having first and second devices for projecting radiant energy. The first device for projecting radiant...
6427082 Optical methods and systems for rapid screening of the cervix  
A method and a system is provided for discriminating between healthy cervical tissue and pathologic cervical tissue based on the fluorescence response of the tissue to laser excitation (LIF) and...
6422994 Fluorescent diagnostic system and method providing color discrimination enhancement  
A fluorescent imaging device to prevent the breakdown of a fluorescent image high-sensitivity imaging apparatus has a light source for endoscope use which selectively switches between an excitation...
6421553 Spectral data classification of samples  
A system and method for classifying tissue by application of discriminant analysis to spectral data. Spectra are recorded as amplitudes at a series of discrete wavelengths. Pluralities of reference...
6418339 Method and apparatus for determining the lines of optimal direction for surgical cuts in the human skin  
The invention relates to a method and a device for in vivo detection of the direction of Langer's lines in the skin. Light is irradiated into the skin as primary light at one defined site ( 7 )...
6415172 Optical imaging of turbid media with depth-related discrimination  
The method for scanning a turbid medium involves displacing an optical signal source over a first face of the medium and a corresponding optical detector over an opposite face from one respective...
6413084 Method and system of scanning  
In accordance with a specific embodiment of the present invention, an image is projected upon a surface. The image can include a pattern having a plurality of individual shapes used to measure and...
6411839 Fundus blood vessel examination apparatus  
A blood vessel examination apparatus includes a presentation device for presenting a fixation reference mark to the eye to be examined, an irradiation device for irradiating a blood vessel on the...
6411838 Systems and methods for optical examination of samples  
The present invention relates to systems and methods for examining a sample using a substantially monostatic, substantially confocal optical system comprising transmitting optics that focus an...
6405073 Miniature spectrometer system and method  
A miniature spectrometer can be used in situ to diagnose tissue and organs through tissue autofluorescence.
6397099 Non-invasive imaging of biological tissue  
An optical system for in vivo, non-invasive imaging of tissue change includes an optical module with an array of input ports and detection ports located in a selected geometrical pattern to provide...
6393315 Detecting and mapping of inflamed zones in a living tissue  
A method for detecting and mapping inflamed zones in living tissues and a device for implementing the method. The method includes subjecting the tissues to be analyzed to a luminous excitation with...
6385484 Spectroscopic system employing a plurality of data types  
A system and method for classifying specimens using a plurality of spectral data types. Spectra are recorded as amplitudes at a series of discrete wavelengths. Pluralities of reference spectra are...
6381489 Measuring condition setting jig, measuring condition setting method and biological information measuring instrument  
A measurement condition setting fixture 2 is secured to a measurement site 1 of a living body prior to the measurement. At the time of measurement, a light irradiation section 3 and a light...
6381018 Method for measuring changes in light absorption of highly scattering media  
The noninvasive measurement of variations in absorption that are due to changes in concentrations of biochemically relevant compounds in tissue is important in many clinical settings. One problem...
6377840 Signal acquisition and processing system for reduced output signal drift in a spectrophotometric instrument  
A spectrophotometric instrument including a source of measurement light signals having measurement light wavelengths, and a probe having a tissue-engaging surface, a plurality of send fibers...
6377842 Method for quantitative measurement of fluorescent and phosphorescent drugs within tissue utilizing a fiber optic probe  
A fiber optic based probe has been designed to sample the fluorescence or phosphorescence signal from animal or human tissues, such that the light intensity is not multiply scattered. This type of...
6374128 Blood vessel imaging system  
A blood vessel imaging system includes a measuring light source which emits a measuring light beam. An optical heterodyne detection system consists of an optical system which splits the measuring...
6364831 Endofluorescence imaging module for an endoscope  
An endofluorescence module is utilized with an interventional device insertible in a body to provide at least one fluorescence excitation source. The module can be attached to the distal end of an...
6364829 Autofluorescence imaging system for endoscopy  
A system and method for imaging tissue autofluorescence through a video endoscope is described, comprising a light source capable of providing both ultraviolet light capable of inducing tissue...
6360115 System for imaging mechanically stabilized tissue  
A system is provided having a clamping apparatus with first and second members, which are spaced apart from each other. An attachment mechanism is connected to the first member for attaching the...
6356780 Method and apparatus for managing peripheral devices in a medical imaging system  
A technique for managing data relating to peripheral devices and subsystems in an imaging system includes providing memory circuitry and, where desired, signal processing circuitry resident in the...
6352502 Methods for obtaining enhanced spectroscopic information from living tissue, noninvasive assessment of skin condition and detection of skin abnormalities  
Disclosed is a method for obtaining feedback to drive a servo system for aligning and maintaining alignment in optical systems that bring light to an in vivo skin sample, for adjusting the focus of...
6351663 Methods for diagnosing and treating conditions associated with abnormal vasculature using fluorescent dye angiography and dye-enhanced photocoagulation  
Methods concerning medical uses for fluorescent dyes, e.g., Indocyanine green (ICG), fluorescein, rose bengal, for diagnosis and treatment. Methods for enhancing the clarity of fluorescent dye...
6347244 Process and arrangement for targeted application of a therapy beam, particularly for the treatment of diseased areas in the eye  
The invention is directed to a process for the targeted application of therapy radiation in the treatment of diseased areas in the eye by means of a therapy beam which is directed into the eye...
6345195 Methods and apparatus for 3D scanning of the human body form  
A method for scanning an inner surface through an outer layer of material, the method including the steps of a) creating an energy beam with a wavelength, intensity, cross-section, and impact angle...
6345194 Enhanced high resolution breast imaging device and method utilizing non-ionizing radiation of narrow spectral bandwidth  
The present invention provides a method and apparatus for high resolution breast imaging using collimated non-ionizing radiation in the near ultraviolet, visible, infrared and microwave regions...
6343227 Miniature spectrometer  
A miniaturized spectrometer is adapted for placement within a body near tissue to be characterized. The spectrometer includes a light source and a plurality of light detectors. The light source...
6343228 Method and apparatus for fluorescence imaging of tissue  
Fluorescence imaging of tissue is used as a diagnostic tool in which geometric effects and specular reflections are compensated for by normalizing a fluorescence image with a cross-polarized image.
6339716 Method for determining viability of a myocardial segment  
A method of determining the viability of a hibernating or stunned myocardial segment comprises the administration of ribose, a vasodilator and an inotropic agent. The preferred agent is dobutamine,...
6337993 Blood flow measuring apparatus  
A blood flow measuring apparatus includes a system control unit that sends outputs for controlling the start and end of the measurement to optimum gain calculation units, which calculate the...
6336044 Reliable body fat measurement in self-service health parameter Measuring system  
In a self-service health parameter measuring apparatus and method, a person's elbow is placed at a spatial reference point, and means surrounding a user's forearm locate an infrared body fat...
6331700 Detector array variable gain amplifiers for use in a laser imaging apparatus  
A detector array for a laser imaging apparatus comprises a plurality of detectors disposed in an arc around an opening in which an object to be scanned is disposed; and a variable gain integrator...
6332093 Scanning module for imaging through scattering media  
A scanning module for imaging through scattering media is provided. The scanning module image through scattering media while alleviating adverse effects of the weak transmission through highly...
6332092 Optical probe having and methods for uniform light irradiation and/or light collection over a volume  
A variety of optical probes and optical methods have utility in the examination of various materials, especially materials in the interior of cavities having restricted access through orifices or...
6330468 System using green light to determine parmeters of a cardiovascular system  
A reflectance pulse oximeter that determines oxygen saturation of hemoglobin using two sources of electromagnetic radiation in the green optical region, which provides the maximum reflectance...
6327493 Light scanning devices of a water-tight structure to be inserted into a body cavity to obtain optical information on inside of a biological tissue  
A light scanning device has a tip structure which includes a light scanning part connected to a light source, and which is insertable into a body cavity and is formed so as to be water-tight. A...
6327489 Method of localizing an object in a turbid medium  
The invention relates to a method of localizing an object in a turbid medium. After measurement of the intensities for a plurality of light paths between the light sources and the detectors, the...
6324418 Portable tissue spectroscopy apparatus and method  
A portable tissue spectroscopy apparatus includes at least one light source, at least one light detector, a power source and a controller module all disposed inside a housing that is insertable...
6324419 Apparatus and method for non-invasive measurement of stretch  
A method and apparatus for noninvasive, non-contacting measurement of stretches and deformations on the surface of a material or an object by utilizing changes which occur in the reflection...
6317624 Apparatus and method for demarcating tumors  
The invention features an apparatus and method for demarcating the margins of a tumor in a target tissue by exposing the target tissue to radiation of a wavelength that induces fluorescence in...
6311083 Method for determining an examination point for the diaphanoscopic examination of a being and device for realizing the same  
In a method and an apparatus for locating an examination size for diaphanoscopic examination of a living subject, a region of the living subject wherein the optimum examination location is...
6304771 Systems and methods for imaging fluorophores  
The systems comprise source means for illuminating the fluorophores with diffuse photon density waves of a first specified wavelength, whereby the fluorophores will fluoresce re-radiated diffuse...
6292686 Apparatus and method for thermal tissue modulation  
Disclosed is a tissue modulation device for use dining spectroscopy of tissue of a subject. In one embodiment, the device comprises an inner sheath, an outer sheath and a window disposed through...
6285904 Method and apparatus for determining fat content of tissue  
A method and apparatus for determining characteristics of tissue is disclosed. The method comprises supplying optical energy to a tissue and detecting at a plurality of locations consequent energy...
6280386 Apparatus for enhancing the visibility of a luminous object inside tissue and methods for same  
Imaging of objects within tissue is enhanced by applying a contrast agent to a sample to be imaged to augment the emissions from an object, thereby forming a luminous object. The tissue is then...
6275718 Method and apparatus for imaging and analysis of ocular tissue  
A method and accompanying apparatus are provided for in vivo imaging of corneal tissue which, in general, includes a laser beam having a substantially planer configuration so as to illuminate the...
6275726 Methods of enhanced light transmission through turbid biological media  
A new process to increase light transmission in biological tissue has been developed. The technique involves temporarily replacing tissue water with a fluid that has a refractive index closer to...
6272367 Examination of a biological tissue using photon migration between a plurality of input and detection locations  
A spectroscopic method and system for examination of biological tissue includes multiple input ports optically connected to at least one light source, multiple detection ports optically connected...