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6788965 Intelligent system for detecting errors and determining failure modes in noninvasive measurement of blood and tissue analytes  
An intelligent system for detecting errors and determining failure modes operates on an absorbance spectrum of in vivo skin tissue. Application of the system results in improved prediction accuracy...
6780158 Signal processing method and pulse wave signal processing method  
A first signal and a second signal are provided as two continuous signals having an identical fundamental frequency. A first spectrum which is either one of a frequency spectrum or a frequency...
6778846 Method of guiding a medical device and system regarding same  
A method and system to guide a medical device within a patient using image data, e.g., chemical image data, includes acquiring image data of a view region within the patient. A movable element of...
6775565 Imaging apparatus for displaying concentration ratios  
Imaging apparatus for representing an image of concentration ratios between a first and a second substance in a region of interest of an object, with different measuring values being represented...
6772003 Endoscope apparatus  
A general-light observation light image can be obtained by illuminating the polarized frame sequence light or polarized white light, for example. In addition, a parallel polarized component and a...
6766187 Method for detecting coagulation in laser treatment of blood vessels  
Onset of coagulation of blood in a blood vessel irradiated by electromagnetic radiation is detected by directing light at the blood vessel and monitoring the intensity of a portion of the light...
6763259 Surgical system supported by optical coherence tomography  
An OCT-supported surgical system includes an OCT module that includes a surface scanner, the position of which can be sensed by a position sensing unit, and an evaluation and display unit, which is...
6763262 Method and apparatus for detecting tumorous tissue  
The present invention relates to an apparatus for detecting tumorous tissue comprising at least one excitation light source 12 , which first excitation light source 12 emits a first excitation...
6760613 Substantially monostatic, substantially confocal optical systems for examination of samples  
The present invention relates to systems and methods for examining a sample using a substantially monostatic, substantially confocal optical system comprising transmitting optics that focus an...
6754518 Method and apparatus for detecting an object within a dynamic scattering media  
A method of detecting an object located within a dynamic scattering media, includes i) directing a continuous coherent light wave of predetermined wavelength into the media; ii) detecting...
6748259 Optical imaging of induced signals in vivo under ambient light conditions  
A method for detecting and localizing a target tissue within the body in the presence of ambient light in which an optical contrast agent is administered and allowed to become functionally...
6748251 Method and apparatus for detecting mastitis by using visual light and/or near infrared lights  
A method for diagnosing mastitis of cows, includes the steps of (1) irradiating visual light rays and/or near infrared rays in a wavelength range of 400 to 2500 nm into urine, raw milk or a mammary...
6745067 System for marking the locations of imaged tissue with respect to the surface of the tissue  
A system is provided for marking on a recording medium ( 36 ), such as a label, the location of imaged tissue with respect to an exposed surface of the tissue ( 34 ). Tissue is imaged by a...
6738659 Optical imaging using the temporal direct reflective signal from a minimized pulse width laser  
A laser is used to radiate a non-homogeneous body comprising two or more materials, with varying scattering characteristics with reference to the radiation. The ballistic or snake radiation is...
6735458 Self-calibrating optical imaging system  
The present invention generally relates to optical imaging systems and methods for providing images of two-dimensional and/or three-dimensional distribution of properties of chromophores in various...
6735463 Doppler flow imaging using optical coherence tomography  
A method for generating a velocity-indicating, tomographic image of a sample in an optical coherence tomography system includes the steps of (a) acquiring cross-correlation data from the...
6728565 Diagnostic catheter using a vacuum for tissue positioning  
A diagnostic catheter using a vacuum for tissue positioning is provided. A method for analyzing tissue in accordance with one embodiment of the present invention includes inserting a catheter...
6728561 Multispectral image processing method, apparatus and computer program product for determining the blood oxygen saturation in a vessel  
Methods, apparatus and computer program products are provided for more accurately determining the percent transmittance of a vessel, such as a retinal vessel, at each of a number of different...
6721583 Method for non-invasive identification of individuals at risk for diabetes  
The invention provides methods for the use of Raman spectroscopy to non-invasively detect molecular characteristics of the constituents of the aqueous humor, vitreous humor, lens or retina. The...
6716162 Fluorescent endoscope apparatus  
A fluorescent endoscope apparatus in which the fluorescent light, which becomes noise, emitted from the photographic element propagating the autofluorescent light emitted from a living-tissue...
6718196 Multimodality instrument for tissue characterization  
A system with multimodality instrument for tissue identification includes a computer-controlled motor driven heuristic probe with a multisensory tip. For neurosurgical applications, the instrument...
6699198 Ocular-blood-flow meter  
An ocular blood-flow meter includes an optical system for applying measuring light to a blood vessel of a subject eye, and for receiving light scattered by the blood vessel of the subject eye. A...
6701181 Multi-path optical catheter  
First and second optical-redirectors mounted on a catheter couple radiation to a target along separate first and second paths. Either the first or second optical-redirectors, or both, can include a...
6697652 Fluorescence, reflectance and light scattering spectroscopy for measuring tissue  
Preferred embodiments of the present invention utilize a plurality of spectroscopic techniques to measure characteristics of tissue useful in the diagnosis of disease. Fluorescence, reflectance and...
6687520 Analysis of a composition  
An analysis apparatus, in particular a spectroscopic analysis apparatus, comprises an excitation system (exs) for emitting an excitation beam (exb) to excite a target region during an excitation...
6687534 Fluorescent-light image display apparatus  
A fluorescent-light image display apparatus for displaying on a monitor a fluorescent-light image emitted from a target area irradiated by a excitation light. A photo-detector inputs the output...
6685650 Fundus blood flowmeter  
When a blood flow velocity in a blood vessel on the fundus is to be measured, a cofocal aperture is inserted to eliminate the influence of scattered light from regions other than a measurement...
6684099 Apparatus and method for reducing spectral complexity in optical sampling  
An optical sampling subsystem and method that reduces the effect of errors in an optical sampling subsystem when heterogeneously distributed samples are measured in the path of a spectrometer. The...
6681130 Method for improving the accuracy of data obtained in a laser imaging apparatus  
A method for collecting data for use in image reconstruction of an object being scanned, comprises providing a plurality of detectors disposed in an arc around the object being scanned to detect...
6678541 Optical fiber probe and methods for measuring optical properties  
A probe for the characterization of optical properties, including scattering and absorption properties of a sample, such as medical and industrial samples, includes an illumination fiber to radiate...
6675035 Phantom for optical and magnetic resonance imaging quality control  
A breast-shaped phantom for optical imaging comprises a cup in the shape of a human breast in its natural pendant position and a filler occupying the volume of the cup. The cup forms an outer skin...
6668185 Endoscope apparatus for setting a scanning area  
An endoscope apparatus that has an OCT function and can efficiently obtain an optical tomographic image is provided. An image of an area within a body cavity is displayed on a monitor, and an...
6668187 Optical mammography  
Apparatus for imaging cross-sectional views of the inner structure of the breast, the apparatus comprising: a source of light ( 12 ) illuminating the breast situated at a first position of the...
6667803 Calibration mode recognition and calibration algorithm for spectrophotometric instrument  
A spectrophotometric instrument including light signal sources, a detector, a processor/controller, a probe and a calibration device. The light signal sources include a source of measurement light...
6665555 Radiosurgery methods that utilize stereotactic methods to precisely deliver high dosages of radiation especially to the spine  
A system for delivery of high dosage of radiation to a targeted spinal area is provided. This is accomplished by a system which provides for precise immobilization and positioning of the treated...
6665556 Method and apparatus for examining a tissue using the spectral wing emission therefrom induced by visible to infrared photoexcitation  
Method and an apparatus for examining a tissue using the spectral wing emission therefrom induced by visible to infrared photoexcitation. In one aspect, the method is used to characterize the...
6662039 Optical probing of neuronal connections with fluorescent indicators  
This invention provides methods of identifying a connection between a first neuron and a second neuron or plurality of neurons in a neural tissue slice with a fluorescent indicator. This invention...
6662042 Diagnostic tomographic laser imaging apparatus  
A laser imaging apparatus comprises a platform for supporting a female patient in frontdown, prone position, including an opening permitting a breast of the patient to be vertically pendant below...
6662030 Non-invasive sensor having controllable temperature feature  
Devices and methods for non-invasively measuring at least one parameter of a sample, such as the presence or concentration of an analyte, in a body part wherein the temperature is controlled. The...
6662040 Methods of photoacoustic imaging  
The invention relates to a method of generating an image of an animate human or non-human animal body or part thereof. The method comprises administering to said body a physiologically tolerable...
6658282 Image registration system and method  
An apparatus for registering a series of video images of a spherical or quasi-spherical surface subject to movement relies on projecting at least four diffusely scattering spots of light on the...
6652836 Method for viewing tumor tissue located within a body cavity  
Methods are provided for in vivo detection of diseased tissue in a subject, such as tumor tissue located in a body opening, by administering to the subject a biologically compatible fluorescing...
6654630 Apparatus and method for the optical imaging of tissue samples  
A catheter based optical system for generating data as to the condition of a tissue sample of a mammalian vessel. The system includes an elongated catheter shaft having a tissue engaging distal end...
6652459 Ophthalmic uses of lasers  
There is disclosed a method for analysis and therapy of the eye utilizing laser-induced ultrasound.
6650923 Method for accessing the left atrium of the heart by locating the fossa ovalis  
Disclosed is an access catheter for identifying and providing access through a tissue structure such as the fossa ovalis on the intraatrial septum. The access catheter comprises an elongate...
6647285 Optical probe with light fluctuation protection  
An optical probe for tissue identification includes an elongated body. Optical fibers are located within the elongated body for transmitting light to and from the tissue. Light fluctuation...
6643538 Directional intraoperative probe  
An introperative surgical probe incorporating both a fiber optic imaging system and multi-element beta/gamma radiation directional indicating system is described.
6640132 Forensic hyperspectral apparatus and method  
This invention relates to portable imaging devices, such as hyperspectral imaging devices, useful for forensic and other analysis, and methods for using these devices. Devices of the present...
6640131 Device for photodynamic diagnosis or treatment  
An endoscopic or microscopic apparatus for diagnosis by means of a light-induced reaction in biologic tissue “in vivo” which is created by a photo-amboceptor or by autofluorescence is provided....
6640129 Determination of liver function using the rate at which plasma disappears  
A method and a device for determining liver function are described. Liver function is determined after injection of an indicator dye into the bloodstream, optical measurement of the resulting...