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5846834 |
Method for assaying photosensitizing drug in whole blood
A concentration of a photosensitizing drug in a patient, for PhotoDynamic Therapy treatment of the patient by a treatment light at a treatment light wavelength, is determined by the steps of...
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5845640 |
Chemiluminescent sources for photodynamic therapy and photomedicine
An optical source (10) for exciting a photosensitive drug that responds to light within a predetermined band of wavelengths. The optical source uses a chemiluminescent source in combination with at...
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5842995 |
Spectroscopic probe for in vivo measurement of raman signals
An optical probe is disclosed which is suitable for rapidly measuring Raman spectra in vivo. The probe is designed to minimize interfering Raman and fluorescence signals generated within the probe...
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5836883 |
Measuring the characteristics of a scattering medium
Apparatus for measuring characteristics of a scattering medium. A light source irradiates the medium to be measured with a plurality of measurement light beams. A wavelength selector unit...
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5833612 |
Method and apparatus for diagnosis skin lesions
A method and apparatus for determining skin lesion parameters comprise directing light to the skin in which the lesion is located and monitoring the reflection of that light. Then, the spatial and...
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5832921 |
Analog heater control for medical instrument
An instrument for determining a characteristic of a biological fluid or a control includes a heater and a heater control. The heater comprises a heater element, supported in heat conducting...
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5832931 |
Method for improved selectivity in photo-activation and detection of molecular diagnostic agents
A method for the imaging of a particular volume of plant or animal tissue, wherein the plant or animal tissue contains at least one photo-active molecular agent. The method includes the steps of...
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5830135 |
Fuzzy logic alarm system for pulse oximeters
A new alarm system for pulse oximeters, based on fuzzy logic, will differentiate false alarms, caused by artifact, from true alarms. Numeric input variables and corresponding fuzzy sets (oxygen...
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5827191 |
Method and a device for monitoring milk volume during breast feeding
A method for monitoring a volume of milk during breast feeding utilizes an elastic nipple shaped cover applied over a nipple area of a woman's breast with holes in the cover positioned above the...
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5827190 |
Endoscope having an integrated CCD sensor
An apparatus and method for imaging diseases in tissue are presented. The apparatus employs a light source for producing excitation light to excite the tissue to generate autofluorescence light and...
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5820558 |
Optical techniques for examination of biological tissue
Methods and systems are described that examine a subject positioned between an input port and detection ports of a spectroscopic system applied to the subject. At least one source of a visible or...
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5819736 |
Viewing method and apparatus particularly useful for viewing the interior of the large intestine
An optical viewing device includes a housing of a size and shape for introduction into the large intestine of a subject and for movement therein in either direction, and an image transducer located...
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5816245 |
Electronic pneumothorax monitoring device
The device presented here is a device for detecting the presence of pneumothorax in a patient including a non-coherent light source for shining light on a patient, mounted on a first patch, capable...
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5813987 |
Spectral volume microprobe for analysis of materials
An optical probe collects light emanating from a specimen that selectively andpreferentially represents a localized volume element within the sample, with illuminationintensity and collection...
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5813988 |
Time-resolved diffusion tomographic imaging in highly scattering turbid media
A method for imaging objects in highly scattering turbid media. According to one embodiment of the invention, the method involves using a plurality of intersecting source/detectors sets and...
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5807261 |
Noninvasive system for characterizing tissue in vivo
A tool for nondestructive interrogation of the tissue including a light source emitter and detector which may be mounted directly on the surgical tool in a tissue contacting surface for...
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5807262 |
Device for localizing an object in a turbid medium using a modulated light source
A device (700) for localizing an object (726) in a turbid medium (710) includes one light source (722) and two detectors (723,724), being symmetrically situated relatively to the light source...
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5807387 |
Optical designation device especially for microsurgical operations
Optical designating device, especially for use in microsurgery, comprising a tool-carrier stage (2) integral with the optical instrument (1), supporting at least one light source (4, 5) for...
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5807263 |
Imaging of biological tissue using photon migration with high directionality techniques
A method and system for examination of a subject positioned between input and detection ports of the spectroscopic system applied to the subject. The systems shown include at lease one light source...
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5799656 |
Optical imaging of breast tissues to enable the detection therein of calcification regions suggestive of cancer
A method for detecting the presence of one or more calcifications within a portion of a turbid medium, such as a breast tissue. According to one aspect, the method involves illuminating at least a...
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5792051 |
Optical probe for non-invasive monitoring of neural activity
The invention features an optical probe for non-invasive monitoring of neural activity. The optical probe includes a light source constructed to introduce electromagnetic radiation of a visible or...
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5788639 |
Confocal imaging through thick dermal tissue
A handheld confocal imaging system for in vivo observation of dermal and subdermal tissue allows diagnosis of conditions substantially beneath the surface of the skin. A confocal head has optics...
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5787888 |
Absorption tomography system and method using direct reconstruction of scattered radiation
A method for the direct reconstruction of an object from measurements of the transmitted intensity of diffusively scattered radiation effected by irradiating the object with a source of continuous...
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5788634 |
Multi purpose sensor
The multi-purpose sensor includes a pair of arms, light-emitting device and light-receiving device that are fitted in an end portion of the arms, respectively, and electrodes that are made of an...
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5787890 |
Eye examination apparatus employing polarized light probe
Apparatus is provided for determining the topography, thickness, and fiber orientation of the nerve fiber layer at the fundus of the eye by measuring the polarization shift induced in a return beam...
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5787887 |
Apparatus for tissue examination using bidirectional transirradiation with light
An apparatus for examining tissue with light, for identifying inhomogeneities, such as tumors, in the tissue, bidirectionally transirradiates the tissue with light, and detects the light emerging...
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5785658 |
In vivo tissue analysis methods and apparatus
A tool for nondestructive interrogation of the tissue including a light source emitter and detector which may be mounted directly on the surgical tool in a tissue contacting surface for...
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5782771 |
Dual, fused, and grooved optical localization fibers
Optical localization fiber embodiments (200, 260, 270, 290, 310, 330, and 350) suitable for preoperative localization of soft tissue lesions by X-ray mammography, CT MRI, ultrasonography or nuclear...
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5782770 |
Hyperspectral imaging methods and apparatus for non-invasive diagnosis of tissue for cancer
Techniques and devices for diagnosing tissue via hyperspectral imaging are presented. A three dimensional "image" where one dimension contains spectral information is formed from a region of...
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5782755 |
Monitoring one or more solutes in a biological system using optical techniques
A scheme for monitoring one or more solutes in a biological system comprising the steps of: delivering light into a biological system containing one or more solutes, the light having a wavelength...
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5779631 |
Spectrophotometer for measuring the metabolic condition of a subject
One preferred embodiment utilizes differential measurement of radiation that migrated in two migration paths between two source (100) detector (110) pairs placed on the head in a manner that each...
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5772597 |
Surgical tool end effector
A tool for nonactive interrogation of the tissue including a light source emitter and detector which may be mounted directly on the surgical tool in a tissue contacting surface for interrogation or...
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5772598 |
Device for transillumination
Human or other tissue is transluminated by light from a coded aperture and focussed on a focal plane in which the object is positioned. The light traversing the light is collimated and a...
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5769076 |
Non-invasive blood analyzer and method using the same
A non-invasive blood analyzer contains a light applicator for illuminating a detection region under the skin of a living body including a blood vessel; a camera for capturing an image of the...
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5769081 |
Method for detecting cancerous tissue using optical spectroscopy and fourier analysis
A method for detecting cancerous tissue using optical spectroscopy and Fourier analysis. According to a preferred embodiment, a tissue sample is illuminated with light at a wavelength of...
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5769791 |
Tissue interrogating device and methods
A tool for nondestructive interrogation of the tissue including a light source emitter and detector which may be mounted directly on the surgical tool in a tissue contacting surface for...
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5766127 |
Method and apparatus for improved photoplethysmographic perfusion-index monitoring
An improved method and apparatus for the monitoring perfusion of the tissue of a patient by arterial blood is provided. An optical path length change is calculated for a number of digitized samples...
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5762609 |
Device and method for analysis of surgical tissue interventions
A class of novel surgical tools constructed from the surgical tools and a tissue state monitoring device to assess or image changes in the chemical or structural composition of tissue over time,...
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5762607 |
Emission tomography system and method using direct reconstruction of scattered radiation
A method for the direct reconstruction of an object from measurements of the quantum efficiency determined from both a diffusing wave and a reradiated diffusing wave effected by irradiating the...
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5758653 |
Simultaneous absorption and diffusion imaging system and method using direct reconstruction of scattered radiation
A method for the direct reconstruction of the absorption and diffusion images from measurements of the transmitted intensity of the scattered radiation effected by irradiating the object with a...
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5752519 |
Device and method for detection, localization, and characterization of inhomogeneities in turbid media
The present invention provides a detection or imaging device and method that measures an effect upon the path traveled by a radiative wave through a medium where scattering of the radiative wave is...
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5752914 |
Continuous mesh EMI shield for pulse oximetry sensor
An improved electromagnetic shield for a photodetector which uses a wire mesh screen laminated to an insulating layer. A portion of the wire mesh screen and laminated layer sandwich can then be cut...
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5749830 |
Fluorescent endoscope apparatus
A fluorescent endoscope apparatus having: an endoscope that irradiates a subject portion to be observed with light transmitted through a light transmission device to obtain an object image of the...
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5738101 |
Optical imaging through turbid media with a degenerate four-wave mixing correlation time gate
Optical imaging through turbid media is demonstrated using a degenerate four-wave mixing correlation time gate. An apparatus and method for detecting ballistic and/or snake light while rejecting...
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5730700 |
Method for measuring incident light in a body cavity
An obturator for measuring incident light in a remote situs such as a body cavity which includes a treatment tubular member through which light is delivered to the remote situs and one or more...
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5730133 |
Optical functional mamoscope
The invention belongs to the field of medicine and biology, and more specifically, the invention encompasses an apparatus for performing functional imaging of biological objects. It can be used to...
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5722407 |
Apparatus and method for examining tissue with light of different wavelengths
In an apparatus and method for examining tissue by transillumination of the tissue, light having different, defined wavelengths is emitted from a plurality of monochromatic light sources into...
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5713364 |
Spectral volume microprobe analysis of materials
An optical probe collects light responses from a specimen that selectively and preferentially emanates from a localized volume element within the sample, with illumination irradiance and collection...
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5701902 |
Spectroscopic burn injury evaluation apparatus and method
A burn evaluation apparatus and related method, that allows a surgeon to make a quick evaluation of the extent and depth of a skin burn injury by employing induced ultraviolet or blue light...
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5699798 |
Method for optically imaging solid tumor tissue
The present invention provides a method and apparatus for determining the presence of solid tumor tissue, for identifying and mapping the margins of solid tumors during surgical or diagnostic...
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