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8133696 |
Method for determining thrombin activity
Methods and kits to determine thrombin activity are provided. They have the great advantage that there is no need to measure the whole calibrator curve in each individual medium, since a...
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8076144 |
Protocol for risk stratification of ischemic events and optimized individualized treatment
A hemostasis analyzer, such as the Thrombelastograph® (TEG®) hemostasis analyzer is utilized to measure continuously in real time, the hemostasis process from the initial fibrin formation, t...
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8070678 |
Detection of restenosis risk in patients receiving a stent by measuring the characteristics of blood clotting including the measurement of maximum thrombin-induced clot strength
A method of selecting a stent for implantation in the circulatory system of a human being includes the steps of determining a threshold level of platelet hyper-coaguability (PHC). One marker of PHC...
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8008086 |
Protocol for monitoring direct thrombin inhibition
A hemostasis analyzer, such as the Thrombelastograph® (TEG®) hemostasis analyzer is utilized to measure continuously in real time, the hemostasis process from the initial fibrin formation, t...
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7947505 |
Method for testing efficacy of antithrombotic agent
The present invention provides a method for testing quickly and easily the manner in which an antithrombotic agent inhibits the acceleration of blood coagulation when a platelet agonist causes...
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7939329 |
Protocol for risk stratification of ischemic events and optimized individualized treatment
A hemostasis analyzer, such as the Thrombelastograph® (TEG®) hemostasis analyzer is utilized to measure continuously in real time, the hemostasis process from the initial fibrin formation, t...
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7901629 |
Cartridge device for blood analysis
A cartridge device having a receiving portion for receiving a blood sample and a jack portion for receiving a plug; a stirring device for circulating the blood sample within the receiving portion;...
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7892188 |
Method and apparatus for characterization of clot formation
Methods, apparatus and systems for characterizing changes in at least one physical property of soft tissue. A series of acoustic pulses is generated and directed into the soft tissue such that at...
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7879615 |
Hemostasis analyzer and method
A method and device for blood hemostasis analysis is disclosed. A blood sample is displaced to reach a resonant state. The resonant frequency of the blood sample is determined before, during and...
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7867771 |
Reagent for measuring clotting time and method for stabilizing tissue factor
The present invention provides a reagent for measuring clotting time including a nonionic surfactant, a nickel ion and a tissue factor. A method for stabilizing a tissue factor, and use of a...
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7857761 |
Acoustic blood analyzer for assessing blood properties
An acoustic blood analyzer with a transducer section of acoustic biosensors for measurement of blood properties including, but not limited to blood coagulation, platelet function and various blood...
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7828729 |
Method of measuring bleeding volume
A method of measuring blood clotting ability of a patient. A known volume of blood is dispensed on a reference disc of blotter paper, such that at least one reference blotch is formed on the...
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7775976 |
Method to determine a coagulation property of a fluid
Apparatus and method for analysing a biological fluid sample to determine a disturbance of haemostasis resulting in a change of viscosity.
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7767459 |
Method for determining prothrombin time
A method for determining prothrombin time of a plasma or whole blood sample includes measuring prothrombin time for at least two different dilutions for a test sample to determine tmin or INRmin....
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7767458 |
Method for determining coagulation activation and device for carrying out said method
A method is disclosed of assaying circulating microparticles contained in a sample of whole blood or blood plasma from a patient to determine the patient's ability to generate thrombin or Factor Xa...
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7754489 |
Protocol for risk stratification of ischemic events and optimized individualized treatment
A hemostasis analyzer, such as the Thrombelastograph® (TEG®) hemostasis analyzer is utilized to measure continuously in real time, the hemostasis process from the initial fibrin formation, t...
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7745224 |
Procedure for the standardization of coagulation tests
The present invention lies in the field of coagulation diagnosis and relates to a procedure for the standardization of coagulation tests, where calibrators are used to which a discrete standard...
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7745223 |
Device with novel and improved surface properties
To increase the adhesion strength of coagulated blood on a surface by increasing the surface interaction of blood-inherent components like fibrin/fibrinogen and thrombocytes it is described to...
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7732213 |
Method of evaluating patient hemostasis
A hemostasis analyzer, such as the Thrombelastograph® (TEG®) hemostasis analyzer is utilized to measure continuously in real time, the hemostasis process from the initial fibrin formation, t...
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7588942 |
Standard/reference/control for blood coagulation testing
A whole-blood-based substitute composition that is useful in coagulation assays as a standard, reference, control, calibrator, linearity verifier, or training material is prepared by combining a...
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7544514 |
Method and system for determining platelet-mediated clot formation
The present subject matter concerns methods for determining platelet medicated clot formation. Specifically, the subject matter provides a method for determining platelet-medicated clot formation...
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7439069 |
Blood coagulation test cartridge, system, and method
A system and method for determining a coagulation time, e.g., thrombin time, PT, aPTT, and ACT, of a blood sample deposited in a test cartridge is disclosed. The test cartridge includes a blood...
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7422905 |
Blood coagulation test cartridge, system, and method
A system and method for determining a coagulation time, e.g., TT, PT, aPTT, and ACT, of a test sample deposited in a test cartridge is disclosed. A cartridge housing having upper and lower major...
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7399637 |
Blood coagulation test cartridge, system, and method
A system and method for determining a coagulation time, e.g., TT, PT, aPTT, and ACT, of a blood test sample deposited in a test cartridge is disclosed. A cartridge housing having upper and lower...
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7364545 |
Method of measuring bleeding volume
A method of measuring blood clotting ability of a patient. A known volume of blood is dispensed on a reference disc of blotter paper, such that at least one reference blotch is formed on the...
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7361306 |
Device and method for measuring coagulation time and platelet activity
The present invention refers to a novel device for measuring coagulation time and platelet activity wherein the patient can measure his or her coagulation time and platelet activity without the aid...
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7314596 |
Apparatus for sensing coagulation of blood sample
A blood sample sensing apparatus includes a moving device which moves a sample container containing a blood sample to a sensing position, a turning mechanism which is connected to the moving device...
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7291310 |
Microsystem for determining clotting time of blood and low-cost, single-use device for use therein
A microsystem for determining clotting time of blood and a low-cost, single-use device for use therein are provided wherein the device has no moving parts or expensive optical sensors or magnets....
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7276376 |
Analyzing method of a blood coagulation reaction
An analyzing method of a blood coagulation reaction by detecting an optical change of a blood sample with an elapse of time, the method includes: setting at least one checkpoint or check region...
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7276377 |
Method and apparatus for determining anticoagulant therapy factors
Methods and apparatus are disclosed for determining a new anticoagulant therapy factor (nATF) for monitoring oral anticoagulant therapy to help prevent excessive bleeding or deleterious blood clots...
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7247488 |
Method and kit for testing a multi-channel blood assay cartridge
A method and kit for testing a multi-channel blood-testing cartridge. In particular, blood-testing cartridges are tested with plasma samples with clotting times measured to indicate whether a batch...
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7211438 |
Method and apparatus for predicting the presence of haemostatic dysfunction in a patient sample
Methods for predicting the presence of haemostatic dysfunction in a patient from a time-dependent measurement profile include performing a time-dependent measurement on an unknown sample and...
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7182913 |
Sample retention apparatus for use in measuring hemostasis
A sample retention apparatus for use in a device for measuring hemostasis. The device for measuring hemostasis may include a sample articulation apparatus including a guide shaft coupled for...
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7179652 |
Protocol for monitoring platelet inhibition
A hemostasis analyzer, such as the Thrombelastograph® (TEG®) hemostasis analyzer is utilized to measure continuously in real time, the hemostasis process from the initial fibrin formation, t...
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7144495 |
Electrochemical test strip with an integrated micro-needle and associated methods
Methods and devices for electrochemically detecting a change in the viscosity of a fluid are provided. In the subject methods, a fluid sample (e.g., a whole blood sample) is introduced into an...
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7071001 |
System and method for in vitro bleeding time testing
The invention includes an in vitro bleeding time device having an opening through a sheet of material across an outlet. At least a portion the sheet of material contains a coating which includes...
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6980958 |
Apparatus and methods for monitoring and modifying anticoagulation therapy of remotely located patients
A patient apparatus is configured to receive and analyze information regarding patient compliance with anticoagulation medication and self-test coagulation regimens related to anticoagulation...
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6955923 |
Device and method for investigating the flowability of a physiological fluid sample
To investigate the flowability of a physiological fluid sample, an uptake passage (12) for the fluid sample (16), an actuator device (18) for the cyclic change in orientation of measuring particles...
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6890299 |
Method and apparatus for monitoring hemostasis in connection with artificial surface devices
A method and apparatus for monitoring hemostasis in a connection with a recipient of an artificial surface device provide a multi-phase monitoring protocol. In a first, pre- and intra-operative...
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6849456 |
Test strip qualification system
In connection with a fluidic medical diagnostic device that permits measurement of the coagulation time of blood, software, methods and associated devices for quality control are provided. The...
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6797519 |
Method and apparatus for diagnosing hemostasis
A system and method for diagnosing hemostasis utilizing a communication network. A blood hemostasis analyzer tests a blood sample and provides a parameter indicative of hemostasis. The blood...
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6787363 |
Method and apparatus for hemostasis and blood management
A procedure for hemostasis and blood management, particularly for cardiovascular procedures, provides: sampling instructions, i.e., when to draw blood samples and how to pre-treat the blood...
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6773923 |
Induced aggregation and agglutination of platelets
The invention relates to a method for measuring the aggregation or agglutination of platelets, where a reaction mixture is mixed in a first reaction phase, and is mixed less vigorously or not at...
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6759009 |
Method and device for clotting time assay
A self-contained analyzer quantitatively detects a clotting event in a biological fluid. The device includes a base having an open reservoir for receiving the biological fluid. A carrier for a...
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6746872 |
Control compositions and methods of use for coagulation tests
Compositions, methods, devices and kits for use in the calibration of coagulation tests. The control compositions include particles capable of aggregating in plasma and calcium ions which, when...
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6730026 |
Medical system for monitoring a measured value of a patient relating to blood-clotting
A medical system for monitoring a measured value of a patient characterizing blood clotting and/or for setting a medication that influences blood clotting for a patient in a home environment, has a...
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6709390 |
Method, device and catheter for in vivo determining blood properties such as blood viscosity
The invention relates to a method for determining properties of blood, such as the blood viscosity of a person, comprising of generating in vivo for a determined time, by means of an electrical...
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6699718 |
Method, reagent and test cartridge for determining clotting time
The invention is a method, reagent and test cartridge for the determination of the clotting time of a blood sample by means of a reagent containing tissue factor and a sulfatide. In an alternative...
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6686204 |
Collection device
The present invention is a container assembly that includes a coating composition on an interior surface of the container assembly and more particularly a coating composition for rapid clotting of...
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6676902 |
Method and device for testing a sample of fresh whole blood
A method and device for testing a sample of fresh whole blood. In particular the present invention provides a method and device for testing a sample of fresh whole blood to determine whether a...
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