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7611830 |
Device to lavage a blood vessel
The present invention provides for compositions and methods for the preservation of tissues and organs ex vivo and in situ. In addition, the present invention provides for kits that may be used in...
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7559953 |
Method for fixing tissue
A method of preparing a fixed biological tissue includes, shaping the biological tissue, cross-linking the biological tissue, sterilizing the biological tissue, and inactivating prions in the...
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7513866 |
Intestine processing device and associated method
A device for preparing small intestines of a vertebre is provided. The device includes a body for cooperation with the small intestines. The body defines an external periphery of the body. The...
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RE40570 |
Apparatuses and methods for treating biological tissue to mitigate calcification
An apparatus for treating fixed biological tissue to inhibit calcification of the biological tissue following implantation thereof in a mammalian body. The apparatus includes a container for...
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7438722 |
Method for treatment of restenosis
A method for inhibiting restenosis is described. The method comprises implanting a stent in a patient's vasculature and simultaneously delivering a restenosis-inhibiting medicine to the treatment...
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7429241 |
Dural graft and method of preparing the same
A dural graft is provided having improved stiffness characteristics relative to conventional dural substitutes. The dural graft can be formed from a collagen material having a stiffness between...
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7427261 |
System for preparing a craft vessel for anastomosis
A system for preparing a graft vessel for anastomosis includes one or more tools held within a functional package. The package includes a tray and tray top, either or both of which may include one...
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7353153 |
Method and system for modeling bone structure
The present invention discloses a structural and mechanical model and modeling methods for human bone based on bone's hierarchical structure and on its hierarchical mechanical behavior. The model...
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7348175 |
Bioreactor with plurality of chambers for conditioning intravascular tissue engineered medical products
A microprocessor controlled and instrumented bioreactor for conditioning intravascular tissue engineered medical products. One bioreactor design including an integrated pump to provide a relatively...
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7322932 |
Method for suturelessly attaching a biomaterial to an implantable bioprosthesis frame
A bioprosthetic valve graft comprises a valve frame and valve flaps, the latter acting to open or close a valve aperture to directionally control fluid flow through the bioprosthesis. The...
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7306627 |
Acellular matrix grafts of collagen and elastic fiber
Acellular matrix grafts are provided with are isolated from natural sources and consist essentially of a collagen and elastin matrix which is devoid of cellular components. The grafts are useful...
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7300444 |
Surgical system and method for connecting hollow tissue structures
A system for performing anastomosis between a graft vessel and a target vessel includes a tissue effector that may be configured to deploy a user-selectable number of connectors. The system...
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7294144 |
Preserved implantable vessel derived from a human umbilical cord or placenta
A preserved vessel isolated from a human umbilical cord or placenta and lyophilized for use as an allograft which improves blood supply to human tissue without antigenicity.
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7211040 |
Vein harvesting system and method
A system and a method for harvesting a section of a blood vessel from a patient's body for further use. The system includes an expandable hood that creates a workspace for the dissection and...
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7185597 |
Method for manufacturing a medical implant
A method for stitching thread onto the wall of a tubular medical implant (preferably a graft) employs a sewing machine with an elongate bobbin or a needle on an elongate element, depending on...
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7175979 |
Preserved tissue matrix of a hollow organ, particularly of a blood vessel, a method of producing same, and the use thereof
The invention relates to a preserved, deantigenated tissue matrix of an animal or human hollow organ, e.g. of a blood vessel, of the ureter or urinary bladder, which matrix is autologous, allogenic...
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7156803 |
Devices for controlling fluid flow through a medium
A fluid flow system for preparing an implantable substrate is provided having a fluid permeable container that is capable of retaining a biocompatible, implantable substrate, and a driver mechanism...
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7141064 |
Compressed tissue for heart valve leaflets
A process and system for compressing bioprosthetic tissue for use in medical implants. The process involves placing the tissue between two compressive surfaces and applying a force to reduce any...
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7137947 |
Endovascular prosthesis having a layer of biological tissue
An apparatus ( 10 ) for grafting of a blood vessel ( 12 ) and a method of forming the apparatus ( 10 ) is provided. The apparatus ( 10 ) comprises an expandable support member ( 16 ) having inner...
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7121999 |
Method of preparing layered graft prostheses
The invention is directed to bioengineered graft prostheses made from two or more superimposed, chemically bonded layers of processed tissue material prepared from cleaned tissue material derived...
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7070557 |
Tissue graft material and method of making
The present invention relates to a method of making a tissue graft material. The method includes placing body tissue and a blood component in a chamber and extruding the body tissue and blood...
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7066875 |
Apparatus and method for vein removal
A device and method for removing a generally cylindrical tissue structure such as a blood vessel from the body of a human or animal. The device includes a body portion having distal and proximal...
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7060022 |
Decellularized vascular prostheses resistant to thrombus occlusion and immunological rejection
The present invention relates to decellularized vascular prostheses that are resistant to thrombus occlusion and have a low level of immunogenicity. The vascular prostheses are denuded of cells,...
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7037332 |
Medical device with coating that promotes endothelial cell adherence
A medical device coated with one or more antibodies and one or more layers of a matrix is disclosed. The antibodies or fragments thereof react with an endothelial cell surface antigen. Also...
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7029434 |
Methods for treating implantable biological tissues to mitigate post—implantation calcification
A method for treating fixed biological tissue inhibits calcification of the biological tissue following implantation thereof in a mammalian body. The method includes placing the biological tissue...
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7011623 |
Ex vivo remodeling of excised blood vessels for vascular grafts
The present invention provides an ex vivo vascular remodeling methods and system by which an excised, small diameter blood vessel can be harvested and expanded to provide viable vascular grafts, as...
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7008763 |
Method to treat collagenous connective tissue for implant remodeled by host cells into living tissue
The invention relates to a method of treatment of collagenous connective tissue removed from a donor for implant into a recipient which is re-habited or re-colonized by host cells without an immune...
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7001328 |
Method for using tropoelastin and for producing tropoelastin biomaterials
It is a general object of the invention to provide a method of effecting repair or replacement or supporting a section of a body tissue using tropoelastin, preferably crosslinked tropoelastin and...
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6991628 |
Device and method for creating a vascular graft in vitro
Methods and apparatus are provided for forming a vascular graft in vitro by axially distending a blood vessel to induce growth. The apparatus comprises a chamber containing a tissue culture medium,...
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6986735 |
Method of making a bioremodelable vascular graft prosthesis
The invention is directed to methods of making bioremodelable graft prostheses prepared from cleaned tissue material derived from animal sources. The bioengineered graft prostheses of the invention...
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6976952 |
Expanded polytetrafluoroethylene vascular graft with coating
A vascular graft comprised of a tubular polytetrafluoroethylene (ePTFE) sheet is provided. The ePTFE sheet has a substantially uniform coating of bioresorbable gel material, for example gelatin, on...
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6939668 |
Compositions and methods for treatment of lung transplants
Methods and compositions for pre-treatment of lung transplants to reduce susceptibility to post-operative B. cepacia infection are provided. The methods and compositions employ saccharides,...
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6899728 |
Reinforced graft
A graft is provided with a flexible sheet of graft material to which is sewn a reinforcing wire, preferably of shape-memory alloy. Sewing of the wire is carried out while the sheet is substantially...
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6899669 |
Autologous vascular grafts created by vessel distension
Devices and methods are provided for forming a vascular graft by axially distending a blood vessel to induce growth. In one embodiment, a device for distending a blood vessel of a human or animal...
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6878168 |
Treatment of bioprosthetic tissues to mitigate post implantation calcification
Bioprosthetic tissues are treated by immersing or otherwise contacting fixed, unfixed or partially fixed tissue with a glutaraldehyde solution that has previously been heat-treated or pH adjusted...
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6866686 |
Tissue graft
The present invention relates to a method of preparing a tissue graft material. The invention also relates to a multipurpose tissue graft material and to methods of using same as a replacement for...
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6824560 |
Double-butted superelastic nitinol tubing
A medical device such as a stent made from single or double-butted tubing is disclosed. The butted tubing may be made from stainless steel or a nickel-titanium (nitinol) alloy. The butted tubing is...
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6821513 |
Method for enhancing hematopoiesis
A method is provided for enhancing hematopoiesis. The method includes transplanting at least a therapeutically effective portion of an isolated vascular tissue into a subject, wherein the vascular...
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6796977 |
Variable graft tensioner
A graft preparation board that enables an exact tensioning of soft tissue grafts. The graft preparation board allows the amount of tensile load to be easily determined so that the operator can...
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6787357 |
Plasma-derived fibrin-based matrices and tissue
The invention is directed to use of fibrin as an extracellular matrix and, together with cells, its use in forming engineered tissue. The engineered tissue can include the synthetic manufacture of...
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6786862 |
Graft vessel preparation device and methods for using the same
A graft vessel preparation device and a method for using the graft vessel preparation device is provided. The graft vessel preparation device establishes and maintains a critical dimension on a...
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6716239 |
ePTFE graft with axial elongation properties
An improved ePTFE material and method of preparing the improved ePTFE material provides a tubular structure with enhanced axial elongation, radial expansion, and physical recovery characteristics.
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6716225 |
Implant devices for nerve repair
An implant device including a tubular matrix made of a biocompatible and bioresorbable biopolymeric material. The matrix has a first end and a second end, a wall of a homogeneous thickness; a...
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6705986 |
Vein harvesting system and method
A system and a method for harvesting a section of a blood vessel from a patient's body for further use. The system includes an expandable hood that creates a workspace for the dissection and...
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6685625 |
Curved implantable sheath and method of making same
A method for making a curved implantable sheath includes placing a sheet of flexible material into engagement with a member having a curved surface having a desired configuration. The sheet and...
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6668836 |
Method for tissue expansion using pulsatile motion
A method of increasing the rate of expansion of tissue area and volume, either in vivo or in vitro, which comprises preparing a tissue for expansion and subjecting the tissue to stretching forces,...
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6663617 |
Devices for creating vascular grafts by vessel distension using fixed post and moveable driver elements
Devices and methods are provided for forming a vascular graft by axially distending a blood vessel to induce growth. The device preferably comprises a stretching mechanism which includes (i) a...
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6652595 |
Method of repairing inguinal hernias
A universal, surgical prosthesis for hernia repair is provided in the form of a foldable sheet. The prosthesis includes a barrier layer formed of a material adapted to prevent biological adherence...
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6626823 |
Implant material
Disclosed are tissue implant materials for use in grafting procedures. More particularly non-vascular tissue for use as vascular graft material and a method of vascular grafting using non-vascular...
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6592618 |
In vitro modification of cardiac valvular xenografts
The present invention is directed to methods for obtaining heart valves from a donor animal that have a reduced tendency to cause inflammation when implanted into a human patient. The valves...
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