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8906048 Modular vessel harvesting system and method  
A vessel harvesting system that is suitable for harvesting target vessels such as the saphenous vein or radial artery for cardiac artery bypass graft surgery. The system includes a vessel...
8876692 Method and device for preserving the vitality and function of a harvested blood vessel  
Blood vessel preservation technology is disclosed wherein harvested blood vessels are attached to stationary attachment fixtures at one end, and to a non-stationary (freely extending) fixture at...
8846390 Methods of conditioning sheet bioprosthetic tissue  
Methods for the conditioning of bioprosthetic material employ bovine pericardial membrane. A laser directed at the fibrous surface of the membrane and moved relative thereto reduces the thickness...
8834349 Tissue modification  
A tissue modification apparatus includes a first and a second guide, a first and a second set of mounts, and a first and a second actuator. The first guide defines a first axis, and the second...
8790241 Selective adherence of stent-graft coverings  
A method for making a radially expandable stent-graft, including positioning a radially expandable stent member concentrically over a first polymeric member, locating a second polymeric member...
8785196 Methods for modulating osteochondral development using bioelectrical stimulation  
Compositions and methods are provided for modulating the growth, development and repair of bone, cartilage or other connective tissue. Devices and stimulus waveforms are provided to differentially...
8777835 Vein harvesting system and method  
A tissue illumination system and a method for harvesting a section of a blood vessel from a patient's body for further use. The tissue illumination system includes a light catheter inserted into a...
8684960 Endothelial scaffold graft and method therefor  
An endothelial scaffold may used to form a graft with an endothelial lining or endothelium. The scaffold allows a natural vessel or other endothelial lumen to line a channel of the scaffold to...
8669043 Cyclic implant perfusion, cleaning and passivation process and implant produced thereby  
A method for perfusion of a porous implant which achieves efficient interpenetration of desired factors into and removal of undesirable factors from the pores of the implant, cleaning of the...
8660664 Methods for forming implantable medical devices  
A method of forming an implantable medical device includes providing an implantable microstimulator. The microstimulator includes a body with a first end and an opposing second end. The...
8591544 Suture loop construct with free floating needle and method of surgery  
A system and method for tissue repair employing a continuous loop of suture attached to a free floating needle. The free floating needle is not swaged on the suture so that, after passing the...
8540619 Fabric cutting system and method  
A fabric cutting system and/or method can include a mandrel having a body and first and second legs, a centered chuck, and an offset chuck, each chuck configured to receive either one of the legs...
8491457 Tissue engineered blood vessels  
The invention is directed to methods for preparing artificial blood vessels by preconditioning a matrix seeded with endothelial cells to fluid flow conditions that mimic blood flow.
8470022 Implantable valve  
Described are implantable prosthetic valve devices comprising isolated granulation tissue. Also described are methods of treatment that include implanting at least one of these valves within a body...
8409847 System and method for controlling the diameter of a mammilian hybrid coronary bypass graft  
Systems and methods are provided for controlling the diameter of a mammalian hybrid coronary bypass graft. The system includes a controller having at least one input for receiving information and...
8399243 Method of manufacturing a tissue-engineered prosthesis  
Developing heart valves are exposed to dynamic strains by applying a dynamic pressure difference over the leaflets. The flow is kept to a minimum, serving only as a perfusion system, supplying the...
8353814 Apparatus and method for mounting an external scaffold to a vascular graft  
A method for securing a compliant scaffold to an outer surface of a vascular graft includes positioning the scaffold radially about an elongated support tube which includes first and second...
8337554 Skin substitute membrane, mold, and method of evaluating external preparation for skin  
A skin substitute membrane includes a surface on one side including a groove-shaped depressed portion and a planar portion, the depressed portion having a cross section having a chamfered V-letter...
8329450 Methods and apparatus for organ support  
An organ support apparatus includes: (a) a fluid circuit defining upstream and downstream legs adapted to be connected to an organ to be supported; (b) a circulation pump connected to the fluid...
8318414 System and method to simulate hemodynamics  
A system for hemodynamic simulation comprises a vessel having properties of a blood vessel, a reservoir containing a quantity of fluid, tubing connecting the vessel and reservoir, and at least one...
8292799 Biological artificial blood vessel and method of making  
A prosthetic device for implantation into a human body is made by a method that includes the steps of providing a natural animal tissue that has a substrate, crosslinking and fixing the substrate,...
8202725 Cell sodding method and apparatus  
Tissue engineering methods and biochamber apparatus are provided for making tissue grafts for implantation into a patient. The methods include applying a sustained low magnitude pressure gradient...
8192348 Engineered blood vessels  
The present invention relates to engineered blood vessels and methods of making such vessels using matrices comprising endothelial and smooth muscle cells, or cells capable of differentiating into...
8172746 Compliant venous graft  
A venous graft for replacement of a section of an artery and methods of making the graft. The graft comprises a flexible, resilient, generally tubular external support and a vein segment carried...
8162815 Method and device for preserving the vitality and function of a harvested blood vessel  
A blood vessel preservation device is disclosed comprised of a vessel cannister, cannister cap, vessel alignment insert, pulsatile pump and both inlet and outlet tubing. The vessel canister is...
8158407 Systems and methods of coating a hybrid hemodialysis access graft or a hybrid femoral artery bypass graft in a mammal  
Hybrid synthetic grafts and embodiments of systems and methods for producing hybrid vascular grafts that can yield implantable grafts that combine synthetic grafts with living cells. Embodiments of...
8142991 Cyclic implant perfusion, cleaning and passivation process and implant produced thereby  
This invention is a novel method for perfusion of a porous implant which achieves efficient interpenetration of desired factors into and removal of undesirable factors from the pores of the...
8123672 Blood vessel preparation and preservation kit  
A vessel preparation and preservation kit supports a blood vessel during processing for use in bypass graft surgery. The device comprises a clamshell base having first and second trays latchable in...
8088060 Progenitor endothelial cell capturing with a drug eluting implantable medical device  
A medical device for implantation into vessels or luminal structures within the body is provided, which stimulates positive blood vessel remodeling. The medical device, such as a stent and a...
8048442 Modified heparin-based coatings and related drug eluting stents  
Systems comprising modified heparin-based coatings to form coatings on medical devices are provided. The systems improve the suitability of the heparin-based coatings.
8039246 Systems and methods of promoting endothelialization of a hybrid hemodialysis access graft or a hybrid femoral artery bypass graft in a mammal  
Hybrid synthetic grafts and embodiments of systems and methods for producing hybrid vascular grafts that can yield implantable grafts that combine synthetic grafts with living cells. Embodiments of...
RE42857 Method of laser cutting pericardial tissue for use with an implantable medical device  
A method of cutting material for use in an implantable medical device employs a plotted laser cutting system. The laser cutting system is computer controlled and includes a laser combined with a...
8034608 Systems and methods of promoting endothelialization of a hybrid hemodialysis access graft or a hybrid femoral artery bypass graft in a mammal  
Hybrid synthetic grafts and embodiments of systems and methods for producing hybrid vascular grafts that can yield implantable grafts that combine synthetic grafts with living cells. Embodiments of...
7968329 Method of conditioning a hybrid synthetic tubular structure to yield a functional human hybrid coronary bypass graft  
A method of yielding a functional human hybrid coronary bypass graft is provided. The method includes conditioning a hybrid synthetic tubular structure having stem cells and/or endothelial cells on...
7968335 Cell culturing method using biomechanical stimulation loading and system therefor  
A cell culturing method employing biomechanical stimulation loading and a system for applying, in in vitro culture, stimulation similar to vertical weight load stimulation or sideward shear stress...
7964387 Method of conditioning a hybrid synthetic tubular structure to yield a functional human hybrid hemodialysis access graft  
A method of yielding a functional human hybrid hemodialysis access graft is provided. The method includes conditioning a hybrid synthetic tubular structure having stem cells and/or endothelial...
7959553 Vein harvesting system and method  
A tissue illumination system and a method for harvesting a section of a blood vessel from a patient's body for further use. The tissue illumination system includes a light catheter inserted into a...
7887558 Modular vessel harvesting system and method  
A vessel harvesting system that is suitable for harvesting target vessels such as the saphenous vein or radial artery for cardiac artery bypass graft surgery. The system includes a vessel...
7857748 Photocurable endoprosthesis methods of manufacture  
Methods of manufacture of endoprostheses comprising one or more photocurable materials are disclosed. The endoprostheses may comprise regions wherein the photocurable materials are selectively...
7851200 Bioreactor for growing engineered tissue  
A bioreactor and a method for growing engineered tissue provide facing surfaces in a vessel for containing cell-culture media. The facing surfaces are equidistant and define a gap therebetween...
7846123 Conduit device and system for implanting a conduit device in a tissue wall  
Various embodiments of the present invention provide a conduit device including an attaching device configured for defining a helical pathway through a tissue wall and complementary ring in...
7833148 Lumen formation-inducible material and instrument to be inserted into the body  
The present invention discloses a fistula formation-inducing material having a property of forming a fistula wherein cells are exposed on at least a portion of the fistula luminal surface. This...
7811315 Implant valve for implantation in a blood vessel  
An implant valve for implantation in a blood vessel is comprised of a flexible tube and a hollow, substantially cylindrical support with a casing, expandable in diameter from an initial position to...
7785438 Multilayer composite vascular access graft  
A multilayer composite vascular access graft and a method of constructing such a graft are disclosed. The mcVAG has improved performance characteristics, which include desirable handling...
7775965 Decellularized grafts from umbilical cord vessels and process for preparing and using same  
A tissue graft is disclosed that includes a decellularized umbilical vessel having a luminal surface and an ablumenal surface, wherein the decellularized umbilical vessel is prepared by an...
7763081 Tissue graft  
The present invention relates to a method of preparing a tissue graft material. The invention also relates to a multipurpose tissue graft material and to methods of using same as a replacement for...
7759120 Seeding implantable medical devices with cells  
Apparatus and methods for seeding an implantable medical device, such as a vascular prosthesis, with cells, such as endothelial cells, are described. The invention supports techniques for seeding a...
7753840 Tissue material process for forming bioprosthesis  
A biomaterial useful for bioprostheses such as bioprosthetic heart valves is provided in which the fixed tissue has improved elastic properties. The high elastin-containing biomaterial is further...
7745105 Method of preparing soft tissue for a biological scaffold by lyophilizing, heating and elastase treatment  
A method for preparing a scaffold material for use in the prosthesis therapy is disclosed. The method comprises (a) lyophilizing a segment of native soft tissue of mammalian origin, heating the...
7744526 Bioreactor for the manufacture of tissue engineered blood vessels  
The invention relates to bioreactors having an enclosed chamber, a sheet growth module, a rollable mandrel, and a clamp for holding the sheet to the mandrel for rolling for the manufacture of a...
Matches 1 - 50 out of 320 1 2 3 4 5 6 7 >