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8095198 Methods for detecting osteolytic conditions in the body  
Methods and systems for detecting a biological response indicative of osteolysis or osteolytic pre-conditions in bone.
8055322 Ion sensor for long term use in complex medium  
Devices and methods for measuring a target ion concentration uses an electrode pair. The pair includes a working electrode and a reference electrode. The working and reference electrodes are...
7970449 Method and apparatus for background current arrangements for a biosensor  
Embodiments of the present invention provide for raising a background current setting for a biosensor above the actual (measured) background current present (i.e., overestimating the background...
7826880 Electrochemical sensor for in-vivo or ex-vivio measurements of the carbon dioxide partial pressure of living tissue  
A physiological sensing device for the measurement of pCO2 includes a closed chamber bounded, at least partially, by a carbon dioxide permeate e membrane (12). There are two electrodes (10) within...
7813780 Biosensors and methods for making and using them  
Embodiments of the invention provide analyte sensors having optimized permselective membranes and methods for making and using such sensors. Embodiments of the invention also provide analyte...
7809441 Implantable medical device with chemical sensor and related methods  
In an embodiment, the invention includes an implantable medical device with a pulse generator and a chemical sensor in communication with the pulse generator, the chemical sensor configured to...
7736310 On-body medical device securement  
Devices and methods for maintaining a medical device on-body are provided. Embodiments include medical device securement systems having first and second on-body securement elements. Also provided...
7729737 Method and apparatus for background current arrangements for a biosensor  
Embodiments of the present invention provide for raising a background current setting for a biosensor above the actual (measured) background current present (i.e., overestimating the background...
7630747 Apparatus for ascertaining blood characteristics and probe for use therewith  
An apparatus for use with a patient having a vessel carrying blood to ascertain characteristics of the blood. The apparatus includes a display module and a probe having a distal extremity adapted...
7389132 Mold-in method and apparatus  
The present invention mainly relates to a method and apparatus for measuring the concentration of a solute in a solvent. Disclosed is an apparatus or method for determining the concentration of a...
7383072 Sweat sensor system and method of characterizing the compositional analysis of sweat fluid  
A method of sensing the concentration level of at least one particular electrolyte in the sweat fluid of a subject, includes providing a sweat sensor system having sweat fluid absorbing material,...
7383071 Microsensor system and method for measuring data  
One embodiment is a microprobe. An example of the microprobe comprises a housing having an aperture. This example of the microprobe also comprises an ISFET attached to the housing. The ISFET may...
7373195 Ion sensor for long term use in complex medium  
Devices and methods for measuring a target ion concentration uses an electrode pair. The pair includes a working electrode and a reference electrode. The working and reference electrodes are...
7231242 Method for measuring blood urea level by reverse iontophoresis  
A method for measuring and determining urea level in human blood by reverse iontophoresis comprising the following steps of: placing an anode electrode on skin,placing a container comprising a...
6701341 Scalable real-time ultrasound information processing system  
An ultrasound information processing system is disclosed in which ultrasound image data is packetized into ultrasound information packets and routed to one or more of a plurality of processors for...
6616614 Apparatus and method for ascertaining cardiac output and other parameters  
Apparatus for ascertaining cardiac output of the heart of a patient comprising a control and display module. A venous probe is inserted into a vein in the forearm of the patient and is coupled into...
6411834 Biological sensor  
An annul protecting portion 23 having a thickness larger than the thickness of a sensor sensitive portion 1 is provided in such a manner as to surround the sensor sensitive portion 1, the sensor...
6219567 Monitoring of total ammoniacal concentration in blood  
Total ammoniacal concentration (TAC) in blood is measured and displayed on a repetitive basis by a controller driven sensor arrangement which may be utilized either with a catheter structure or...
6023630 Probe assembly and apparatus for measuring the PH of a tissue of a human or animal organ  
A probe assembly includes at least two electrodes for measuring a potential difference between two measurement sites of a tissue of a human or animal organ and at least one sensor for measuring the...
5728281 Implantable medical device including an arrangement for measuring a blood property having a carbon reference electrode  
An implantable medical device for in vivo electrochemical measurements of blood properties, such as measurements of, inter alia, oxygen pressure, glucose and pH, avoids the problem with the...
5698083 Chemiresistor urea sensor  
A sensor to detect and quantify urea in fluids resulting from hemodialysis procedures, and in blood and other body fluids. The sensor is based upon a chemiresistor, which consists of an...
5680858 Method and apparatus for in vivo determination of the concentration in a body fluid of metabolically significant substances  
A method for in vivo determination of the concentration in a body fluid of metabolically significant substance comprises storing of a needle with a sensor in a liquid-filled ampoule, brief...
5617851 Ultrasonic transdermal system for withdrawing fluid from an organism and determining the concentration of a substance in the fluid  
A noninvasive method and apparatus for withdrawing fluid from an organism and determining the concentration of a substance in the fluid is disclosed. The noninvasive apparatus comprises a substance...
5513636 Implantable sensor chip  
An implantable sensor chip, which is preferably small enough to be injected through a hypodermic needle, includes a base constructed of an electrically insulating material, and at least one sensor...
5511547 Solid state sensors  
A stabilized bio-inert sensor for the determination of an analyte, especially pO2, pCO2 and pH, in a medium which comprises a chemical indicator sensitive to the analyte in association with a...
5507289 System and method to diagnose bacterial growth  
A system and a method for monitoring intragastrointestinal concentrations of ammonium, and urease, during short or prolonged periods is presented, as an indicator of the presence and activity of an...
5505828 Calibration solutions useful for analysis of biological fluids and methods employing same  
Novel calibration solutions are provided which are useful, for example, with sensor assemblies used for analysis of CO2, and optionally, for concurrent analysis of O2, especially in combination...
5425868 Sensor for non-invasive, in vivo determination of an analyte and blood flow  
The sensor (1) comprises a sensor body (3) thermostatable by means of a first thermostating system (14,15) and having an outer surface (3a,40a) for application to the human body (28) in heat...
5354448 Electrochemical sensor  
An electrochemical sensor for the determination of the partial pressure of oxygen in a bloodstream comprising a cathode and an anode immersed in an electrolyte contained in a chamber defined by an...
5330634 Calibration solutions useful for analyses of biological fluids and methods employing same  
Novel calibration solutions are provided which are useful, for example, with sensor assemblies used for analysis of CO2, especially in combination infusion fluid delivery/blood chemistry analysis...
5322609 Device for detecting electrolytes in liquid samples  
A biosensor device for detecting electrolytes in liquid samples includes a capillary tube having a lumen extending therethrough. This lumen receives and retains liquid to be sampled for...
5284139 Hemometrix temperature compensation  
A method for converting a value for the partial pressure of oxygen (pO2) in blood at a measurement temperature to a corresponding value at a reference temperature (37° C.). A value for pO2 is ...
5251633 Optical probe  
An improved optical probe for the invasive measurement of partial carbon dioxide pressures is disclosed that minimizes pCO2 reading drift. An optical probe for the invasive measurement of the...
5250419 Method for the direct measurement of at least one chemical parameter of skin using a biosensor  
This biosensor comprises a membrane (8), in which an enzyme catalyzing the transformation of a substrate used in the cutaneous metabolism is immobilized, means for detecting and measuring a...
5192417 Lithium ion sensor  
A lithium ion sensor includes a FET, a redox layer having a redox function covering a gate isolating membrance of the FET, and a lithium ion-sensitive layer selectively sensing lithium ion covering...
5145565 Contamination-free method and apparatus for measuring body fluid chemical parameters  
A sample of a body fluid, such as blood, is collected in a cartridge having a sample chamber for storing the sample and one or more calibration chambers, each for storing a respective calibration...
5078137 Apparatus for measuring oxygen partial pressure and temperature, in living tissue  
A probe adapted for insertion in living tissue for measuring oxygen partial pressure and temperature at a plurality of sites in living tissue is provided. A temperature sensitive resistor is...
5039492 Optical pH and gas concentration sensor  
An optical pH sensor and a gas sensor utilizing the pH sensor. The pH sensor includes an indicator whose absorbance is a function of the concentration of hydronium ions in a media surrounding the...
5018527 Sensor for the measurement of ion activity  
A sensor for measuring the activity of ions by means of ion-selective membranes (4) improves the measuring possibilities and reduces the dimensions of the sensor in that a plurality of such...
4974592 Continuous on-line blood monitoring system  
A continuous on-line blood monitoring system for determining the ionic concentrations of certain ions within blood is disclosed. By use of a synchronized valving mechanism within the device, as...
4890620 Two-dimensional diffusion glucose substrate sensing electrode  
Enzyme electrode assembly suitable for sensing physiologically important molecules such as glucose wherein the rate of accessibility of enzyme substrates to the enzyme is differentially regulated...
4841974 Apparatus and method for the examination of a liquid medium  
A measuring canal is provided which is connected to a catheter. The canal includes a measuring sensor and a reference sensor. The catheter includes several lumens that have a common opening to the...
4835477 Process for the determination of the hematocrit level of whole blood and apparatus for carrying out the process  
There is described a method and apparatus for the determination of hematocrit levels in which both the conductivity of whole blood and the conductivity of blood plasma are determined together....
4815471 Catheter assembly  
A compact catheter assembly provides for the communication of a reference pressure to a pressure-sensing transducer by forming a passageway between spaced electrical conductors mounted on a planar...
4808292 Arrangement for stabilizing a gas-reference electrode  
In a catheter or hollow needle type electrolytic measuring device having a measuring electrode and a gas reference electrode, an arrangement for stabilizing the operation of the gas reference...
4748562 Portable circuit and method for performing a time study and analysis of bodily characteristics  
A portable circuit and method for performing a time study and analysis of bodily ionic characteristics as esophageal pH includes a transducer 11 for measuring pH and generating a proportional...
4706678 Electrochemical reference electrode  
An electrochemical reference electrode having improved potential stability is provided, such reference electrode being suitable for use as a second-order or half-cell component within a system for...
4700709 Apparatus and method for determining ammonium ion concentration and total ammonia concentration in fluids or tissue  
Apparatus comprising an ammonia electrode, a pH electrode and a thermistor is utilized in determining ammonium in concentration and total ammonia concentration by simultaneously measuring to...
4697450 Gas monitor having trend indicators  
An improved device for determining the trend of the partial pressure of a gas, such as oxygen or carbon dioxide, which diffuses outwardly through a patient's skin. The device, such as a cutaneous...
4682602 Probe for medical application  
A medical probe having at least one transducer or electrode for registering or influencing tissue activities is disclosed. The probe comprises a substrate having a supporting surface and a cover...
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