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6567678 Multiplex sensor and method of use  
A method for using a multiplex sensor that provides enhanced selectivity and sensitivity. In this method, one or more parameters of a sample are measured by means of multiple spectroscopic...
6564076 Time-resolved spectroscopic apparatus and method using streak camera  
Methods and apparatus using the principles of time-resolved spectroscopy are disclosed. The present invention employs incident light pulses of sufficiently short duration to permit the rate of the...
6560470 Electrical lockout photoplethysmographic measurement system  
A photoplethysmographic measurement system includes an electrical lockout to effectively prevent users, such as patients and medical personnel, from being exposed to high levels of light energy...
6556854 Blood vessel imaging system using homodyne and heterodyne effects  
A homodyne interference system splits first and second light beams from a common light source and causes the first and second light beams to impinge upon an irradiating point of an organism at...
6556852 Earpiece with sensors to measure/monitor multiple physiological variables  
An apparatus and method for positioning sensors relative to one another and anatomic features in a non-invasive device for measuring and monitoring multiple physiological variables from a single...
6556851 Detection probe for optical spectroscopy and spectrometry  
The invention relates to a detection probe for spectroscopy and/or spectrometry in tissue ( 4 ) with the aid of optical fibers ( 1,2 ). At least one fiber ( 2 ) transmits light into the tissue ( 4...
6556858 Diffuse infrared light imaging system  
An imaging system illuminates body tissue with infrared light to enhance visibility of subcutaneous blood vessels, and generates a video image of the body tissue and the subcutaneous blood vessels...
6549794 Single use disposable protective cap  
A disposable protective cap and method for covering a probe in a spectral imaging apparatus are provided. The cap protects the probe from direct contact with a subject's tissues. The cap is hollow...
6546267 Biological sensor  
A light emitting portion 3 and a light receiving portion 4 are separately formed, and firmly interposed between tape members 21 and 25 and between tape members 23 and 26 , respectively....
6542761 Multifunction sensor  
A device for measuring parameters of medical fluids having a measurement chamber through which the fluid to be measured passes. The chamber is sealed on one side by a flexible membrane, and it also...
6542762 Near-infrared noninvasive determination of pH in pulse mode  
Methods and apparatus for, preferably, determining noninvasively and in vivo pH in a human. The non-invasive method includes the steps of: generating light at three or more different wavelengths in...
6542246 Blood vessel imaging system  
A blood vessel imaging system includes a measuring light source which emits a measuring light beam. An optical heterodyne detection system consists of an optical system which splits the measuring...
6540675 Analyte monitor  
Provided is an analyte monitoring device having a housing, the device comprising: a plurality of needles, each having a tip, a retracted position, a position wherein the tip is extended from the...
6542763 Optical measurement equipment and recording medium and optical measurement method  
In a system for performing imaging measurement of a test object by mounting many optical fibers to the test object, incident positions of the test object on which to illuminate light, detection...
6530915 Photothermal structure for biomedical applications, and method therefor  
A photothermal structure designed for the uniform application of a photothermal material, such as, for example, a dye or a pigment, to a tissue, e.g., the stratum corneum. In one embodiment, the...
6527716 Microporation of tissue for delivery of bioactive agents  
A method of enhancing the permeability of a biological membrane, including the skin or mucosa of an animal or the outer layer of a 20 plant to a permeant is described utilizing microporation of...
6529768 Method and apparatus for acquiring fluorescence images  
Intrinsic fluorescence, which has been produced from living body tissues when excitation light is irradiated to the living body tissues, is detected with an image sensor and is read out as an...
6526299 Spectrum processing and processor  
An elastic scattering spectrum taken from human tissue is taken and preprocessed by dividing the absorption spectrum into a plurality of wavelength ranges and fitting the measured absorption...
6524242 Non-contact method for measuring amount of sebum or oil on substrate in real time using fluorescence dye  
The invention provides a non-contact (non-invasive) method for measuring quantity of sebum oil on skin or other substrate. The method includes applying fluorescent lipophilic dye to the substrate...
6526297 Method and apparatus for quantifying the hypnotic component of the depth of anesthesia by monitoring changes in optical scattering properties of brain tissue  
A method/apparatus for non-invasively measuring a neurological activity state in the brain of a subject to ascertain, for example, the state of the hypnotic component of the subject's anesthesia....
6526309 Transcranial in vivo examination of brain tissue  
An optical system and method for transcranial in vivo examination of brain tissue includes a spectrophotometer coupled to an array of optical fibers and a processor. The array of optical fibers is...
6526298 Method for the non-invasive determination of analytes in a selected volume of tissue  
A method for the determination of concentrations of analytes, e.g., glucose, and other metabolites in human tissue, wherein the temperature of a defined cutaneous volume of tissue, e.g., human...
6522911 Apparatus for imaging a blood vessel  
A first measuring light beam of wavelength λ 1 equal to a wavelength at the isosbestic point between oxyhemoglobin and deoxyhemoglobin and a second measuring light beam of wavelength λ 2 ...
6510329 Detection of sensor off conditions in a pulse oximeter  
A system for detecting sensor off conditions in a pulse oximeter is disclosed. In one implementation, a detector off condition is identified based a volatility of a signal quality of a filtered...
6501973 Apparatus and method for measuring selected physical condition of an animate subject  
An apparatus for measuring at least one selected physical condition of an animate subject is disclosed. The apparatus comprises: (a) a light source; (b) a light receiver that receives resultant...
6501982 System for the noninvasive estimation of relative age  
Noninvasive instrumentation and procedures have been developed for estimating the apparent age of human and animal subjects based on the irradiation of skin tissue with near-infrared light. The...
6501002 Disposable surface wipe article having a waste contamination sensor  
Disclosed is a disposable surface wipe having a sensor which detects bodily waste contamination on a surface and which provides a signal indicating the presence of such contamination, desirably by...
6498942 Optoacoustic monitoring of blood oxygenation  
An optoacoustic apparatus is disclosed which includes a radiation source of pulsed radiation and a probe having a front face to be placed in close proximity to or in contact with a tissue site of...
6491644 Implantable sound receptor for hearing aids  
In an implantable sound receptor for hearing aids, the sound sensor is designed as an optical sensor ( 5 ) and arranged within the ear at a distance from the surface of a sound transmission part (...
6493566 Classification system for sex determination and tissue characterization  
Instrumentation and procedures for noninvasively determining the sex of human and animal subjects in vivo have been developed based on the irradiation of skin tissue with near infrared light. The...
6493565 Examination of biological tissue by monitoring one or more solutes  
This invention is a scheme for monitoring a solute in a biological system comprising the steps of delivering light into a biological system ( 12 ) containing a solute, the light having a wavelength...
6487428 Extravasation detection apparatus and method based on optical sensing  
Extravasation of a fluid applied to a patient is determined by monitoring light transmitted through the tissue of the patient in proximity to a site at which the fluid is being injected. Light is...
6487439 Glove-mounted hybrid probe for tissue type recognition  
A probe configured as a finger tip of a glove used to recognize tissue types in a human patient and adapted to perform both optical and electrical measurements to diagnose tissue type while scanned...
6484044 Apparatus and method for detecting a substance  
An apparatus for detecting a substance in a sample, particularly for in vivo detecting and measuring glucose in body tissue or blood contains a semiconductor laser for emitting mid-infrared laser...
6475144 Non-contact method for measuring amount of skin sebum or oil in real time using fiber optic probe  
The invention provides a non-contact process for measuring amount of sebum or oil on skin or other substrate. Process is preferably done in vivo because of ability to measure formation of sebum/oil...
6470199 Elastic sock for positioning an optical probe  
A positioner, such as an elastic sock, is fitted with an optical probe, preferably designed for pulse oximetry. The sock preferably substantially forms to the shape of a wearer's foot or hand. In...
6466807 Optical glucose detector  
A device for the in vivo measurement of the concentration of an analyte in an aqueous solution comprises a transmitter for illuminating a body part with light at a plurality of predetermined...
6466806 Photoacoustic material analysis  
Disclosed is a method and apparatus for determining the concentration of an interest component in a medium by resonant photoacoustic spectroscopy (RPAS) with a light pulse-train comprising...
6463309 Apparatus and method for locating vessels in a living body  
A method and apparatus for facilitating the locating of vessels in a living body, the apparatus having an enclosure for surrounding a portion of the living body, a light source positioned to...
6449500 Probe for optical measurement  
A second optical component is an optical fiber bundle charged in a clearance between an inner cylinder and an outer cylindrical outer peripheral part in the form of a ring. These elements are...
6442411 Method for improving calibration of an instrument for non-invasively measuring constituents in arterial blood  
The absence of a defined optical pathlength for in vivo measurements creates problems for the noninvasive measurement of analyte concentration. These problems can be reduced by combining...
6437863 Method and apparatus for detecting and measuring conditions affecting color  
A method and apparatus for determining the condition of a test subject based on color uses a color measuring instrument to detect change in a color factor indicative of a condition such as a...
6438397 Method and apparatus for analyte detection using intradermally implanted skin port  
A transcutaneous, implantable skin port sensor includes an access component and a sensor component, both of which can be made from inexpensive biocompatible materials. The access component provides...
6430513 Monitoring constituents of an animal organ using statistical correlation  
Constituents such as oxy- and deoxy-hemoglobin are monitored non-invasively in an animal organ such as a brain with a spectrometric instrument by passing radiation through the organ. Concentrations...
6430422 Intraoral jig for optical measurement  
A jig body of resin is formed with a concave part engaging with an upper backside of teeth and another concave part engaging with a lower backside of teeth, and includes a portion coming into...
6424848 Method for preparing skin surface and determining glucose levels from that surface  
This involves a non-invasive glucose measurement device and a process for determining blood glucose level in the human body using the device. In typical operation, the glucose measurement device is...
6424960 Unsupervised adaptation and classification of multiple classes and sources in blind signal separation  
A computer-implemented method and apparatus that adapts class parameters, classifies data and separates sources configured in one of multiple classes whose parameters (i.e. characteristics) are...
6415167 Fiber optic probe placement guide  
A fiber optic probe placement guide minimizes sampling errors during optical sampling of a tissue measurement site by allowing repeatable placement of the fiber optic probe at a targeted tissue...
6410333 Assessment of human skin damage following exposure to harmful agents  
The present invention relates to the assessment of ultraviolet radiation UV effects on sunscreen-treated and non-treated human skin using a more sensitive technique.
6402690 Isolating ring sensor design  
A monitoring system for monitoring the health status of a patient by performing measurements such as skin temperature, blood flow, blood constituent concentration, and pulse rate at the finger of...