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6697653 Reduced wire count voltage drop sense  
The present invention provides a reduced wire count voltage-drop sense system and method wherein the voltage drop across a load device is determinable using only one sense lead regardless of the...
6697652 Fluorescence, reflectance and light scattering spectroscopy for measuring tissue  
Preferred embodiments of the present invention utilize a plurality of spectroscopic techniques to measure characteristics of tissue useful in the diagnosis of disease. Fluorescence, reflectance and...
6697655 Low power pulse oximeter  
A low power pulse oximeter includes an input stage for amplifying a signal received from a light detector that is switchably connected to the power supply that powers the amplifier. The oximeter...
6697656 Pulse oximetry sensor compatible with multiple pulse oximetry systems  
An oximeter sensor can be used with multiple oximeter systems. The oximeter sensor includes a first light-emitting diode, a second light-emitting diode and a photodetector. Electrical connections...
6694158 System using a portable detection device for detection of an analyte through body tissue  
A portable optical system includes interrogation of an implanted sensor located in a body tissue. The sensor contains a labeled analogue and a reference, which emit light at different wavelengths....
6694157 Method and apparatus for determination of pH pCO2, hemoglobin, and hemoglobin oxygen saturation  
This invention relates to a method and apparatus for in-vivo, real time measurement of pH, pCO 2 , base excess, hemoglobin, and hemoglobin oxygen saturation. Specifically, the invention relates to...
6687532 Optical CT apparatus and image reconstructing method  
An optical CT apparatus 10 is mainly composed of a container 12 filled with an optical interface member 20 ; a light-projecting section, comprising a light source 22 and an optical switch ...
6687521 Noninvasion biological optical measuring instrument, measured portion holding device, and method for manufacturing the same  
The present device is equipped with a measurement site holder 3 that is constructed using a negative impression of the measurement site 10 . As a result, variation in the measured values caused...
6684099 Apparatus and method for reducing spectral complexity in optical sampling  
An optical sampling subsystem and method that reduces the effect of errors in an optical sampling subsystem when heterogeneously distributed samples are measured in the path of a spectrometer. The...
6681126 Method and apparatus for improving the durability of a sensor  
The present invention relates to a method and apparatus for improving the durability of a sensor, specifically one attached by an adhesive material to a subject. Specifically, the present invention...
6681128 System for noninvasive hematocrit monitoring  
A system determines heamtocrit transcutaneously and noninvasively. Disclosed are a finger clip assembly and an earlobe clip assembly, each including at least a pair of emitters and a photodiode in...
6679841 Fluid collection and monitoring device  
An article capable of both collecting interstitial fluid and detecting an analyte in that fluid and a method for use of that article. Preferably, the article is also capable of measuring the amount...
6678542 Calibrator configured for use with noninvasive analyte-concentration monitor and employing traditional measurements  
A method calibrates a monitor that comprises a non-invasive blood constituent monitor and a traditional measurement system. The non-invasive blood constituent monitor includes a thermal gradient...
6678541 Optical fiber probe and methods for measuring optical properties  
A probe for the characterization of optical properties, including scattering and absorption properties of a sample, such as medical and industrial samples, includes an illumination fiber to radiate...
6674916 Interpolation in transform space for multiple rigid object registration  
A method of mapping a chosen point in real space to its corresponding location in image space includes obtaining a diagnostic medical image of a subject including multiple rigid objects, and...
6675029 Apparatus and method for quantification of tissue hydration using diffuse reflectance spectroscopy  
An apparatus and method for non-destructively estimating a tissue property, such as hydration, of a living subject utilizes in vivo spectral measurements made by irradiating skin tissue with near...
6671542 Non-invasive method of determining skin thickness and characterizing layers of skin tissue in vivo  
A novel approach to measuring the overall and layer-by-layer thickness of in vivo skin tissue based on near infrared absorbance spectra is described. The different biological and chemical compounds...
6671526 Probe and apparatus for determining concentration of light-absorbing materials in living tissue  
A probe 1 includes a light irradiating device 2 and a light receiving device 3 , which are oppositely disposed sandwiching living tissue 10 . The light irradiating device 2 includes a light...
6668181 Method for quantification of stratum corneum hydration using diffuse reflectance spectroscopy  
An apparatus and method for non-invasively quantifying the hydration of the stratum corneum of a living subject utilizes in vivo spectral measurements made by irradiating skin tissue with near...
6665551 Current driving system of light emitting diode  
Three current supply lines 44, 45, 41 and connection terminals 32, 34, 30 thereof for respectively driving the light emitting diodes on the probe side are arranged in a light emitting diode...
6662030 Non-invasive sensor having controllable temperature feature  
Devices and methods for non-invasively measuring at least one parameter of a sample, such as the presence or concentration of an analyte, in a body part wherein the temperature is controlled. The...
6662031 Method and device for the noninvasive determination of hemoglobin and hematocrit  
A method for the determination of hemoglobin and hematocrit by means of an apparatus that is capable of controlling the temperature of a defined subcutaneous volume of human skin. The method...
6654620 Method for improving non-invasive determination of the concentration of analytes in a biological sample  
A method for determining the concentration of an analyte in a biological sample comprising the steps of: (1) providing an optical measuring instrument comprising a thermally controllable optical...
6647280 Method and apparatus for processing a physiological signal  
A signal processing method, preferably for extracting a fundamental period from a noisy, low-frequency signal, is disclosed. The signal processing method generally comprises calculating a numerical...
6643020 Optical analysis method for inhomogeneous turbid media  
Light is made incident into an inhomogeneous medium, and transmitted light or reflected light is detected. The intensity of the detected light is represented by the linear sum of exponential...
6636752 Measurement, data acquistion, and signal processing for a photonic molecular probe  
An opto-electronic device utilizes a band of partially polarized polychromatic light for quantitative analysis of a specimen containing a target molecule. The device comprises: a polarizer for...
6636759 Apparatus and method for determination of the adequacy of dialysis by non-invasive near-infrared spectroscopy  
Methods and apparatus for non-invasive tissue urea concentrations during or subsequent to hemodialysis using near-infrared spectroscopy are discussed. Near-infrared tissue spectra can be obtained...
6636753 Solid-state non-invasive infrared absorption spectrometer for the generation and capture of thermal gradient spectra form living tissue  
A solid-state spectrometer for the non-invasive generation and capture of thermal gradient spectra from human or animal tissue. The spectrometer includes an infrared transmissive thermal mass...
6633771 Solid-state non-invasive thermal cycling spectrometer  
A solid-state device for the non-invasive generation and capture of thermal gradient spectra from sample tissue. The device includes an infrared transmissive layered window assembly, a means for...
6631289 System and method of fluorescence spectroscopic imaging for characterization and monitoring of tissue damage  
A method for monitoring a biological tissue includes illuminating the tissue, including a fluorophore, with a wavelength of light, the wavelength selected for exciting the fluorophore, determining...
6625480 Apparatus and method for measuring a concentration of a component of a target material  
Apparatus and method for measuring concentration of a component of target material including a pumping light source for emitting light; a first wavelength conversion unit for converting and...
6625479 Optical sensor for in situ measurement of analytes  
An implantable sensor for use in the detection or quantitative measurement of an analyte in subcutaneous fluid, the sensor being biodegradable or hydrolysable in vivo. The sensor incorporates an...
6622034 Oximeter sensor with functional liner  
This invention is an improve non-invasive electro-optical sensor probe ( 10 ) that is initially L shaped to provide a mechanical means for accurate positioning of the sensor for subsequent use in...
6622032 Method for non-invasive blood analyte measurement with improved optical interface  
A method for non-invasively measuring the concentration of an analyte, particularly blood analyte in blood. The method utilizes spectrographic techniques in conjunction with an improved optical...
6615062 Referencing optical catheters  
The invention provides methods and apparatus to reference or normalize optical measurements, by removing or accounting for background factors and artifacts, such as motion artifacts, that arise...
6615061 Optical sensor having a selectable sampling distance for determination of analytes  
A method and apparatus for the measurement of trans-cutaneous diffuse reflectance at a single sampling distance for determining the concentration of an analyte in a biological sample, such as, for...
6611698 Optical measuring instrument  
A highly reliable optical measuring instrument for multi-channel simultaneous measurement has an intensity of light emitted from a light source modulated at different frequencies and the light is...
6609014 Use of PDT to inhibit intimal hyperplasia  
Long-term dialysis requires provision of safe and reliable vascular access, often in the form of an arteriovenous (AV) fistula. The primary cause of AV fistula loss or failure is stenosis caused by...
6606509 Method and apparatus for improving the accuracy of noninvasive hematocrit measurements  
A device and a method to provide a more reliable and accurate measurement of hematocrit (Hct) by noninvasive means. The changes in the intensities of light of multiple wavelengths transmitted...
6596016 Phototherapy of jaundiced newborns using garments containing semiconductor light-emitting devices  
A phototherapy garment contains a flexible backing material, a transparent liner, and a flexible printed circuit sheet containing surface-mounted light-emitting diodes (LEDs) positioned between the...
6597931 System and method for absolute oxygen saturation  
The present invention generally relates to an apparatus and method for obtaining absolute values of concentrations of chromophores of a medium and/or absolute values of their ratios. More...
6594510 Photonic molecular probe  
An opto-electronic device utilizes a band of polychromatic light for quantitative analysis of a target molecule within a mixed specimen. A movable polarizer produces a segmented band of partially...
6591121 Measurement, data acquisition, and signal processing  
In an opto-electronic device utilizing a band of light for quantitative analysis of a specimen containing a target molecule, the opto-electronic device comprising a specimen cell adapted for...
6587701 Method of assessing tissue viability using near-infrared spectroscopy  
Prolonged and severe tissue hypoxia results in tissue necrosis in pedicled flaps. We demonstrate the potential of near-infrared spectroscopy for predicting viability of compromised tissue portions....
6587703 System and method for measuring absolute oxygen saturation  
The present invention generally relates to apparatus and methods for obtaining absolute values of concentrations of chromophores of a medium and/or absolute values of their ratios. In particular,...
6587702 Classification and characterization of tissue through features related to adipose tissue  
A non-invasive system for characterizing and classifying the state and structure of a tissue sample operates on a near infrared absorbance spectrum of in vivo tissue. A method that uses...
6580935 Method and system for stabilizing reflected light  
A light stabilizing interface operatively linked to a collection wave guides for combining and stabilizing reflected light into a substantially even spatial distribution of light energy with a...
6577884 Detection of stroke events using diffuse optical tomagraphy  
The invention relates to a method of using diffuse optical tomography and oxygen in a stroke patient, or a patient suspected of having a stroke, to detect ischemic events or bleeds in the brain.
6571113 Oximeter sensor adapter with coding element  
An oximeter sensor adapter which allows a sensor without a resistor in parallel with its LEDs to operate with an oximeter expecting such a resistor in parallel. The adapter includes LED drive...
6571117 Capillary sweet spot imaging for improving the tracking accuracy and SNR of noninvasive blood analysis methods  
The accuracy of noninvasive blood analysis methods is limited by the so-called tracking error. The correlation between the component concentration in the probed skin volume and the component...