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5956144 Method and apparatus for use of polarized light vectors in identifying and evaluating constituent compounds in a specimen  
A device and method for determining the identity and concentration of constituent compounds of a test specimen. The device and method are based upon the polarization effect that a specimen will...
5944660 Disposable cartridge assembly with optional integrated temperature control system, and systems containing same  
A cartridge assembly is provided for analyzing characteristics of a sample fluid. The cartridge assembly comprises an assembly body having a passageway, a cavity and, interposed between the...
5935076 Method and apparatus for accurately measuring the transmittance of blood within a retinal vessel  
The method and apparatus for measuring the transmittance of blood within a retinal vessel detects the intensity of light reflected from illuminated portions of an eye, including the retinal vessel...
5931779 Real-time in-vivo measurement of myoglobin oxygen saturation  
A method for determining myoglobin oxygen fractional saturation in vivo in muscle tissue and intracellular oxygen tension (pO 2 ), typically in the presence of hemoglobin, is provided. The method...
5933226 Attachment for a concentration measuring apparatus and a concentration measuring system  
An attachment is designed such that a concentration measuring apparatus is attachable to and detachable from it. Inside the leading end portion of the attachment, leading ends of two light guide...
5924982 Oximeter sensor with user-modifiable color surface  
An oximeter sensor with an emitter and a detector, and a sensor body surface having a first color proximate to at least one of the emitter or detector. The color can be modified by a user to adapt...
5924979 Medical diagnostic apparatus with sleep mode  
A method and apparatus for conserving power in a medical diagnostic apparatus by using a sleep mode during a monitoring state. The sleep mode allows not only the processor to be put to sleep, but...
5916152 Lung permeability analysis  
A spectrophotometric analytical method for lung permeability is described. An exogenous polydispersed macromolecule is administered, and fluid of the patient is evaluated using infrared spectroscopy.
5916153 Multifunction catheter  
A modified Foley type catheter has a pressure sensor near the insertion end, an inflatable balloon, a temperature sensor, a light emitter, and a blood oxygen level detector near the light emitting...
5916171 Tissue monitor  
A single signal-single probe multiparameter analyzer apparatus for monitoring various parameters of the identical volume element of body tissue, which includes an input signal generator, a single...
5911689 Subcutaneous radiation reflection probe  
A subcutaneous radiation reflection probe for measuring oxygen saturation in living tissue includes an elongate drive shaft on one end of which is detachably coupled a mounting cup. The mounting...
5912179 Method for determining a level of oxidative stress of a tissue sample  
Systems and methods for material analysis are disclosed in which an organic sample (e.g., a foodstuff, tissue sample or petroleum product) is illuminated at a plurality of discrete wavelengths...
5908384 Apparatus for non-invasive measurement within a human or animal body  
An apparatus for non-invasive measurement within a human or animal body with an emitter for emitting electromagnetic radiation into the human or animal body and a detector for detecting the...
5893364 Apparatus for light reflection measurements  
An apparatus for light transport measurements on a test object with a measuring head which includes a contact surface for placing against an interface of the test object, light irradiation device...
5891029 Method of and device for positioning a living body for biological measurement and apparatus for measurement of biological information  
To secure a highly accurate measurement value of biological information with minimized variation by positioning a target part of a living body with good reproducibility and by positioning the...
5891021 Partially rigid-partially flexible electro-optical sensor for fingertip transillumination  
A sensor is provided for transillumination of a blood-profused portion of a human fingertip. The sensor includes an opaque, semi-cylindrical substantially rigid cradle member having a photosensor...
5891022 Apparatus for performing multiwavelength photoplethysmography  
A photoplethysmographic measurement device that utilizes wavelength division multiplexing is provided. Signals from multiple light emitters are combined into a single multiplexed light signal in a...
5882940 Method for assaying photosensitizing drug in plasma  
A concentration of a photosensitizing drug in a patient, for PhotoDynamic Therapy treatment of the patient by a treatment light at a treatment light wavelength, is determined by the steps of...
5879294 Tissue chromophore measurement system  
A measurement system and method for measuring a relative concentration of a first form of a chromophore having a first form and a second form. The method comprises irradiating a tissue sample with...
5873821 Lateralization spectrophotometer  
The present invention utilizes differential measurement of radiation that migrated into two migration paths between two source-detector pairs placed on the head in a manner that each path is...
5873831 Method and system for measurement of macular carotenoid levels  
The present invention is directed to a new and useful method and apparatus for use in determining the levels of macular pigments in the tissue of live subjects. Specifically, the method and...
5865167 Method of living system organism diagnostics and apparatus for its realization  
A method of diagnostics of living organism state and an apparatus for its realization, comprising the steps of (i) illuminating living organism surface (1) with electromagnetic radiation from...
5857462 Systematic wavelength selection for improved multivariate spectral analysis  
Methods and apparatus for determining in a biological material one or more unknown values of at least one known characteristic (e.g. the concentration of an analyte such as glucose in blood or the...
RE36044 Path constrained spectrophotometer and method for determination of spatial distribution of light or other radiation scattering and absorbing substances in a radiation scattering medium  
A spectrophotometer for providing an image of a radiation scattering medium having one or more radiation attenuating constituents is disclosed herein. The spectrophotometer includes a light source...
5855551 Integral sheathing apparatus for tissue recognition probes  
The invention incorporates an opto-electronic section in the tip of the sheath cover for a diagnostic probe that makes both electric and optical measurements of tissue contacted by the sheath. In...
5851178 Instrumented laser diode probe connector  
This apparatus places the laser diode light source in the connector affixed to the distal end of the cable, proximate to the patient. The disposable portion of the probe simply consists of the...
5846834 Method for assaying photosensitizing drug in whole blood  
A concentration of a photosensitizing drug in a patient, for PhotoDynamic Therapy treatment of the patient by a treatment light at a treatment light wavelength, is determined by the steps of...
5833602 Process of continuous noninvasive hemometry  
This invention relates to a process of determining continuously and non-invasively (without the withdrawal of blood.) the concentrations of hemoglobin. This is done by measurement of the path...
5825488 Method and apparatus for determining analytical data concerning the inside of a scattering matrix  
A method and an apparatus for determining analytical data concerning the inside of a scattering matrix, in particular of a biological sample. In a detection step detection measurements are carried...
5818985 Optical oximeter probe adapter  
The present invention provides an adapter which actively connects a two terminal oximeter probe or monitor to a three terminal monitor or probe. This is done actively, with the alternating drive...
5813403 Optical measurement of tissue pH  
The invention provides an optical method and apparatus for determining the pH of a tissue. The method includes the step of first irradiating the tissue with optical radiation. The radiation may...
5814599 Transdermal delivery of encapsulated drugs  
Applications of low-frequency (20 KHz) ultrasound enhances transdermal transport of high-molecular weight proteins. This method includes a simultaneous application of ultrasound and protein on the...
5810724 Reusable sensor accessory containing a conformable spring activated rubber sleeved clip  
A reusable accessory for a sensor (such as a pulse oximeter or a plethysmograph) that allows close conformance between the sensor heads and the patient tissue to be measured. The accessory thus...
5807248 Medical monitoring probe with modular device housing  
The manufacture of the electronics component of the probe is simplified by using an integral lead frame on which is mounted all of the passive and active elements so that the entire electronics...
5807246 Display device in medical examination and treatment system  
A pulse oximeter display device which displays oxygen saturation data is provided. The device comprises a multicolor display unit which displays oxygen saturation data in first and second colors. A...
5808304 Method and apparatus for detecting malignancies in living tissue  
The most common method of determining whether a breast contains cancerous tissue utilizes ionizing radiation, i.e. x-rays, which possible have tissue damaging properties. It has been found that...
5807247 Method and apparatus for facilitating compatibility between pulse oximeters and sensor probes  
A sensor probe operable to transmit light of a first wavelength for scattering by a tissue sample is described for use with a pulse oximeter designed to operate with another type of sensor probe...
5795295 OCT-assisted surgical microscope with multi-coordinate manipulator  
Embodiments of the present invention provide method and apparatus for use during a neurosurgical procedure to enable a multi-coordinate manipulator ("MCM") to locate blood vessels and nerves in a...
5795292 Method for improving signal-to-noise in clinical spectrometric procedures  
A method of conducting clinical examination procedures by use of electrically actuated spectrometric apparatus, of the type which uses a sensor that is placed in contact with the patient to...
5792051 Optical probe for non-invasive monitoring of neural activity  
The invention features an optical probe for non-invasive monitoring of neural activity. The optical probe includes a light source constructed to introduce electromagnetic radiation of a visible or...
5792050 Near-infrared noninvasive spectroscopic determination of pH  
Methods and apparatus for, preferably, determining noninvasively and in vitro pH in a human. The non-invasive method includes the steps of: generating light at three or more different wavelengths...
5787887 Apparatus for tissue examination using bidirectional transirradiation with light  
An apparatus for examining tissue with light, for identifying inhomogeneities, such as tumors, in the tissue, bidirectionally transirradiates the tissue with light, and detects the light emerging...
5786592 Pulse oximetry sensor with fiberoptic signal transmission  
A pulse oximetry sensor has a light emitting and light detecting part containing light emitting diodes and a photo detector electrically connected to a pulse oximetry instrument, and a two-halved...
5785651 Distance measuring confocal microscope  
A novel apparatus and method for the quick and accurate determination of surface profile and depth reading within little or no mechanical motion is presented comprising a polychromatic light...
5778879 Electronic blood pressure meter with posture detector  
This invention provides an electronic blood pressure meter which can measure blood pressure with great accuracy. The angle of inclination is detected by inclination sensor and the height of the...
5778878 Laser doppler microscopy methods and instruments  
The velocity of blood cells in skin or other tissue capillaries is determined by a laser Doppler technique. A laser beam is focussed on to a capillary by means of a lens, mirror and beam splitter...
5772588 Apparatus and method for measuring a scattering medium  
An apparatus and method are provided for measuring a scattering medium containing a light absorbing substance. The apparatus includes a light source; a photodetector; a gate voltage applying...
5770454 Method and aparatus for determining an analyte in a biological sample  
A method and apparatus for analytical determination of a concentration of an analyte in a biological sample include a series of hardware elements and method steps which perform at least two...
5766125 Apparatus for determining the concentration of light-absorbing materials in blood  
Light beams of different wavelengths, emitted from a light generating device, are transmitted through a living tissue. The transmitted light beams are converted into electrical signals by a...
5766131 Pulse-wave measuring apparatus  
To achieve a pulse wave measuring apparatus whereby the sensor unit can be easily and consistently worn against the skin surface, a wristwatch type pulse wave measuring apparatus is comprised as...