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6010453 |
Tonometric catheter combination
A tonometric device for use in hollow viscus tonometry and remote sensing of patient fluid parameters is disclosed. The device is capable of monitoring certain critical fluid properties of...
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6010454 |
Fluid and electrolyte balance monitoring system for surgical and critically ill patients
A computer based system for tracking a patient's fluid volume and electrolyte (cation or anion concentration) balances, during the period extending from before surgical procedures through the...
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5976085 |
In situ calibration system for sensors located in a physiologic line
A method is provided for calibrating sensors used to analyze characteristics of physiologic fluids such as blood. The method involves the use of a sensor assembly having an analyte-responsive...
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5978694 |
Method and apparatus for detecting a magnetically responsive substance
Method and apparatus for detecting in a sample a substance which responds to an applied magnetic field, such as a paramagnetic substance. The sample is placed in an applied magnetic field, and the...
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5957839 |
Apparatus and method for continuous monitoring of tissue gas composition and pH using recirculating gas tonometry
A tonometry catheter apparatus comprises an elongate, flexible, multilumen tube having a proximal end to be positioned outside the human body and a distal end to be positioned within a portion of...
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5947911 |
Method and apparatus for reducing purge volume in a blood chemistry monitoring system
A method and apparatus for reducing the volume of fluid required to purge a patient's blood from a blood sampling site after the blood has been sampled for measurement. A coil is formed in the...
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5925021 |
Medication delivery device with a microprocessor and characteristic monitor
A medication delivery device, such as a pen-type injector, jet injector, medication pump, inhaler, spray or the like has a microprocessor coupled to the device that records the date, the time, and...
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5885211 |
Microporation of human skin for monitoring the concentration of an analyte
A method of enhancing the permeability of the skin to an analyte for diagnostic purposes or to a drug for therapeutic purposes is described utilizing microporation and optionally sonic energy and a...
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5882494 |
Polyurethane/polyurea compositions containing silicone for biosensor membranes
A homogenous polymer composition useful as a membrane for biosensors is disclosed. The polymer composition comprises the reaction products of a diisocyanate, a hydrophilic diol or diamine, and a...
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5840055 |
Disposable device for transfer of an active liquid into an intracorporeal cavity
A disposable device for transfer of an active liquid into an intracorporeal cavity, having a central element able to contact the mucous membrane of an intracorporeal cavity; an absorbent peripheral...
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5840020 |
Monitoring method and a monitoring equipment
Monitoring equipment including means for receiving a measurement result indicating the patient's blood glucose level, and for staring it in a first memory means. In order to improve and facilitate...
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5833601 |
Methodology for determining oxygen in biological systems
The invention provides apparatus and methods for measuring oxygen tensions in biological systems utilizing physiologically acceptable paramagnetic material, such as India ink or carbon black, and...
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5832921 |
Analog heater control for medical instrument
An instrument for determining a characteristic of a biological fluid or a control includes a heater and a heater control. The heater comprises a heater element, supported in heat conducting...
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5830129 |
Process and apparatus for measuring blood flow through an organ or other biological tissue
A process for measuring parameters of organs and tissues, especially blood flow through an organ, particularly the liver, is based on a medical technology apparatus that can be constructed in...
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5823953 |
Secretion analysis apparatus and method
A method and device for distinguishing between yeast infection and other secretion-causing conditions makes use of the observation that secretions caused by yeast infection generally have a pH of...
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5814599 |
Transdermal delivery of encapsulated drugs
Applications of low-frequency (20 KHz) ultrasound enhances transdermal transport of high-molecular weight proteins. This method includes a simultaneous application of ultrasound and protein on the...
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5801057 |
Microsampling device and method of construction
A minimally intrusive and less painful, self-use microsampling device and method for the measurement of glucose and other analytes in blood are provided. The device of the invention may have one or...
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5793292 |
System for inhibiting use of a hand-operated machine by an impaired individual through detection of toxins in the individual
A system for inhibiting use of a hand-operated machine by an impaired individual through detection of toxins in the individual has affixed to a portion of the machine which the operator regularly...
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5788631 |
Hollow viscus and solid organ tonometry
Ischemia in a hollow internal organ can be detected in its incipient stages by obtaining a CO 2 sample from within the organ of interest, measuring the partial pressure of CO 2 sample, measuring...
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5787885 |
Body fluid analysis system
A device and method for sampling and testing the breath of human beings to detect maladies in the esophagus, stomach or gastrointestinal tract by the automatic analysis of the chemical contents of...
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5782754 |
Non-invasive monitoring of a constituent of a physiological fluid
For non-invasively monitoring the concentration of a substance in blood, use is made of a pickup unit, with a cavity through which a liquid is passed. The cavity is held against the skin and the...
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5758643 |
Method and apparatus for monitoring blood chemistry
An improved system is disclosed for monitoring a patient's blood chemistry, wherein the system intermittently draws blood samples from the patient into a special sensor assembly having a plurality...
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5758653 |
Simultaneous absorption and diffusion imaging system and method using direct reconstruction of scattered radiation
A method for the direct reconstruction of the absorption and diffusion images from measurements of the transmitted intensity of the scattered radiation effected by irradiating the object with a...
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5735832 |
Reinforced microdialysis probe
A microdialysis probe having a center tube surrounded by a thin dialysis tube (3), which is located between two tubular fitting parts (2, 5). With the purpose of reinforcing the probe and...
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5735274 |
Apparatus and method for analyzing particles including shifting a judgement region
An apparatus and method for analyzing particles includes a distribution data preparation device for measuring parameters that characterize particles contained in a specimen and for preparing a...
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5728074 |
Pen-type injector with a microprocessor and blood characteristic monitor
A medical injection device, such as a pen-type injector has a microprocessor coupled to the injector that records the date, the time, and the amount of each injection. The microprocessor may also...
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5720284 |
Apparatus for measuring hemoglobin
Light of various wavelengths emitted from light sources and transmitted through vital tissues is converted by light sensors and current/voltage transducers, into electric signals. The signals are...
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5713351 |
Intrauterine meconium detection system
A system for intrauterine detection of one or more biological substances, such as meconium or blood, is described. The presence in amniotic fluid of such biological substances indicates an abnormal...
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5706807 |
Sensor device covered with foam membrane
An implant is provided with an open-celled silicone elastomer foam outer layer. The implant may be formed by compressively deforming beads mixed with liquid elastomer in a mold containing a...
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5706806 |
Linear microdialysis probe with support fiber
An improved linear microdialysis probe assembly has a short semipermeable membrane portion containing a flexible, internal support or reinforcement fiber bonded to long lengths of inlet and outlet...
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5676142 |
Method and apparatus for measuring scattering property and absorption property in scattering medium
Measuring scattering and absorption properties of a scattering medium according to the following: (a) causing pulsed measuring light having a predetermined wavelength to enter the scattering...
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5544650 |
Automated specimen classification system and method
A semi-automated method of classifying a histological specimen for the presence of premalignant or malignant cells, including the steps of treating a specimen with an immunohistochemical marker to...
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5490506 |
Peripheral blood flow evaluating apparatus
An apparatus for evaluating a peripheral blood flow of a living subject, including a reflection-type pulse wave detecting device including two pairs of light-emitting and light-receiving elements...
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5477468 |
Concentration analyzer
The concentration analyzer of the present invention is used to determine the cross-sectional concentration at multiple locations within a fluid line, such as an artery or vein, of dissolved...
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5477327 |
High resolution low noise optical polarimeter
Two linearly polarized beams of monochromatic laser light are amplitude modulated with low frequency sinusoids. The first laser is modulated with a sinusoid 90° out of phase from the second laser....
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5471981 |
Method and apparatus for converting a modulated optical signal to an electrical signal with correction for modulation jitter
A method for accurately converting to an electrical signal a modulated optical signal, the modulation frequency of which randomly varies in a narrow range about a predefined optimum modulation...
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5466348 |
Methods and devices for enhanced biochemical sensing
A method and application for detecting and measuring the presence of a binding target material employs a semiconductor device having a receptor-covered surface topgate, separated by a dielectric...
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5441481 |
Microdialysis probes and methods of use
A microdialysis probe arranged to have a primary probe, e.g., an electrical probe, secured to it so that the microdialysis probe extends about and is concentric with the primary probe to enable the...
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5421328 |
Intravascular blood parameter sensing system
A parameter of blood is sensed in vivo with a system which includes a catheter and a probe. The catheter has a lumen extending therethrough, a proximal end, a distal end and a distal opening at the...
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5353791 |
Optical organism measuring apparatus
Disclosed herein is an optical organism measuring apparatus in which cables provided on both light transmission and receiving sides are sufficiently reduced in diameter and provided with...
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5334189 |
Device for controlled diffusion of a chemical substance
A device and methods of use and manufacture are disclosed for controlled diffusion of chemical substances of interest intraorally. The device includes ported structure formed of material that is...
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5251126 |
Diabetes data analysis and interpretation method
An automated diabetes data interpretation method is provided which combines symbolic and numeric computing approaches in order to identify and highlight key clinical findings in the patient's...
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5237993 |
Process and device for determining parameters of interest in living organisms
In order to determine at least one parameter of interest in a living organism, a perfusion is directly introduced in the tissues. After its partial balancing by the tissue parameter of interest,...
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5183042 |
Electromagnetic method and apparatus to measure constituents of human or animal tissue
To deterine glucose or other constituents of the human or animal body, near-infrared radiation containing two alternating wavelengths that have equal extinction coefficients in the tissue is...
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5078135 |
Apparatus for in vivo analysis of biological compounds in blood or tissue by microdialysis and mass spectrometry
The present invention combines microdialysis with mass spectrometry, for example continuous flow fast atom bombardment, to follow the pharmacokinetics of drugs or other compounds directly in the...
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5046497 |
Structure for coupling a guidewire and a catheter
A method and system for introducing one or more devices into a biological fluid vessel. The system includes a device having a coupling structure comprising a pair of spaced-apart fingers adapted...
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4947845 |
Method of maximizing catheter longevity in an implantable medication infusion system
A method of significantly enhancing the period of time that an implanted intraperitoneal catheter used for the delivery of therapeutic medication will operate without encountering significant...
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4911168 |
Method of screening and selecting intraperitoneal medication infusion pump candidates
A method of screening potential recipients of an implantable medication infusion system including an implanted intraperitoneal catheter is disclosed which seeks to select only those candidates who...
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4844096 |
Method of diagnosing growth hormone disorders employing somatostatin infusion
A diagnostic method whereby the sensitivity of inhibition of nocturnal growth hormone secretion by a growth hormone inhibiting factor is tested. The inhibiting factor or hormone, somatostatin is...
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4830849 |
Extravascular circulation of oxygenated synthetic nutrients to treat tissue hypoxic and ischemic disorders
A novel system and method for treating ischemic neurologic tissue is disclosed wherein an oxygenated nutrient emulsion is circulated through at least a portion of the cerebospinal pathway. The...
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