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8834338 Dosimetry implant for treating restenosis and hyperplasia  
The present invention discloses a method of selectively providing radiation dosimetry to a subject in need of such treatment. The radiation is applied by an implant comprising a body member and...
8834340 Radiation containing seeds and method for high visibility magnetic imaging  
A radioactive seed and method for making a radioactive seed with selective magnetic imaging characteristics are provided. The seed includes a housing which may include a metal shell for at least...
8814775 Expandable brachytherapy apparatus and methods for using them  
Brachytherapy treatment apparatus are provided that include an elongate body including a core member and an outer member surrounding and movable relative to the core member. One or more helical...
8808156 Minimally invasive applicator for intraoperative radiotherapy  
The present invention relates to an applicator for delivering any of a plurality of predetermined radiation fields to a target in intraoperative radiotherapy. In a variant, the applicator...
8798716 Fiducial markers and related methods  
In part, the invention relates to fiduciary markers suitable for affixing to a patient that are detectable with respect an imaging modality such as MRI and methods of making the same. The markers...
8795145 Brachytherapy apparatus and methods for using same  
Apparatus, systems and methods are provided for delivering brachytherapy to a target tissue region of a human or other mammalian body. A flexible brachytherapy device may be implanted that includes...
8771161 Expandable brachytherapy apparatus and methods for using them  
Apparatus for delivering brachytherapy to a target tissue region includes an elongate body including a proximal end, a distal end sized for introduction into a tissue tract and carrying a plurality...
8758214 Radiation catheter with multilayered balloon  
A catheter device for irradiating tissue surrounding a body site within a body of a patient, includes an elongated shaft which has a distal portion configured to be deployed within the body site. A...
8758213 Minimally invasive applicators for robotic and non-robotic-assisted intraoperative radiotherapy  
An applicator is provided, for manipulating one or more catheters carrying a radiation generating device, for delivering a radiation field to a target, the applicator having a proximal end and a...
8753255 Methods and compositions for treating luminal inflammatory disease  
Compositions, articles, and methods for treating and imaging vulnerable plaque and other inflamed regions in a patient rely on delivery of a conversion electron emitting source (CEES) to a body...
8740762 Specific inhibition of cPLA2 enhances the efficacy of radiotherapy  
A method for increasing the radiosensitivity of a target tissue in a subject is disclosed. In some embodiments, the methods includes administering a cytosolic phospholipase A2 (cPLA2) antagonist to...
8740763 Multilumen brachytherapy balloon catheter  
The disclosure describes a device for asymmetrical irradiation of a body cavity or site, such as after removal of tissue, e.g. biopsy or lumpectomy. The device includes an elongated tubular shaft...
8734313 Accelerated partial breast irradiation with shielded brachytherapy applicator system and method of use  
The system and methods of the invention partially shields the radiation dose to the skin and/or other anatomical organs by using magnetically responsive material that blocks radiation, which may be...
8734314 Method and kit for delivery of brachytherapy to a subject  
The present invention provides a kit for delivering catheter brachytherapy to a subject comprising a medical balloon catheter (1) having a proximal (2) and distal (3) end, comprising a elongated...
8721514 Electromagnetic pose sensing of HDR brachytherapy applicator  
An implantable applicator (10) has at least one guide channel (12) for guiding a radioactive seed or source (66) to a target region. A plurality of imageable fiducials (40) are configured for...
8702579 Control system and method for precisely guiding a percutaneous needle toward the prostate  
A needle holder device for treating the prostate, involving a series of steps of inserting a needle into the prostate, has a rectal probe for ultrasonic 3D imaging and a computer for processing the...
8696539 Positioning device and a procedure for treating the walls of a resection cavity  
A positioning device (1) for treating the inner walls of a resection cavity, which was created by surgically removing of at least a portion of a tumor in a living body, characterized by the fact...
8696545 System and method for minimally invasive disease therapy  
A system for treating a lesion site of a patient is disclosed. The system includes a cannula having a lumen, a conduit in communication with said lumen, an introducer stylet removably disposed...
8690747 Eyelid plaque  
An eyelid plaque and a method of using the plaque to treat eye cancers. The eyelid plaque is placed on the eyelid such that it defines an enclosure within which the radiation source resides. The...
8690746 Expandable brachytherapy device  
A brachytherapy device for the provision of brachytherapy is disclosed. The brachytherapy device has at least one source lumen located outside a movable surface of the device. The source lumen may...
8684900 Health monitoring appliance  
A heart monitoring system for a person includes one or more wireless nodes forming a wireless network; a wearable body sensor having a wireless transceiver adapted to communicate with the one or...
8684898 Ionizing-radiation-responsive compositions, methods, and systems  
A method composition and system respond to ionizing, radiation to adjust biological activity. In some approaches the ionizing radiation is X-ray or extreme ultraviolet radiation that produces...
8684899 Expandable brachytherapy device  
A method for brachytherapy in a lumpectomy cavity of a breast including, positioning a distal end of a brachytherapy device within the cavity, expanding an expandable surface portion located...
8641592 Method and device for image guided dynamic radiation treatment of prostate cancer and other pelvic lesions  
A method and device for image guided dynamic radiation treatment of prostate cancer and other pelvic lesions including: 1) a unique fan geometry of radiation sources; 2) a special collimation...
8636637 Methods for asymmetrical irradiation of a body cavity  
The disclosure describes devices and methods for asymmetrical irradiation at a body cavity or site, such as after removal of tissue, e.g. biopsy or cancer. One device includes a lumen which is...
8629415 Radiation therapy apparatus  
A radiation therapy apparatus includes a gantry having a central aperture that defines a cavity, in which a patient is positionable. The apparatus also includes a positioning device, with which the...
8602959 Methods and devices for delivery of radiation to the posterior portion of the eye  
Methods and devices for delivering radiation to a target at a posterior portion of an eye using a brachytherapy-administering device adapted to be inserted into a suprachoroidal space of the eye...
8567410 Magnet-field controlled active substance transfer for aerosol therapy  
The present invention relates to aerosols containing magnetic particles, wherein the aerosols comprise magnetic particles and a pharmaceutical active agent. The invention furthermore relates to the...
8571180 Miniature X-ray tube for a catheter  
A miniature X-ray tube for intravascular or intracorporeal radiation treatment in living beings is proposed. The X-ray tube comprises a cylindrical housing section with a longitudinal axis. The...
8568284 Expandable brachytherapy device  
A method for brachytherapy in a lumpectomy cavity of a breast including, positioning a distal end of a brachytherapy device within the cavity, expanding an expandable surface portion located...
8545377 Magazine for chain components for a chain with radiation sources and a system consisting of a chain component and a magazine for chain components for a chain with radiation sources  
A magazine for chain components of a chain with radiation sources comprises a housing as well as a first means for receiving chain components that is mounted in a pivotal manner in the housing and...
8529426 Ionizing-radiation-responsive compositions, methods, and systems  
A method, composition and system respond to ionizing radiation to adjust biological activity. In some approaches the ionizing radiation is X-ray or extreme ultraviolet radiation that produces...
8529427 Applicators and methods for intraoperative treatment of proliferative diseases of the breast  
A device for administering brachytherapy to a patient includes a vessel that may be in the form of a hollow cylindrical cup, for fleshing into and substantially filling the open-ended cavity. The...
8517907 Expandable brachytherapy apparatus and methods for using them  
Apparatus for delivering brachytherapy to a target tissue region includes an elongate body including a proximal end, a distal end sized for introduction into a tissue tract and carrying a plurality...
8517906 Brachytherapy device  
A brachytherapy device is configured for use in a system having a fluid source. The brachytherapy device includes a balloon assembly including an inflation conduit coupled to a distensible portion....
8500693 Autoinjector received in external socket  
The present invention relates to a device for automatic injection of a product, comprising: a body (3) housing a container, the container being movable relative to said body between an initial...
8500618 Dual gynecological balloon packing system  
A gynecological balloon apparatus has a first balloon and a second balloon disposed with a gynecological brachytherapy applicator. The first and second balloons are each movable between an inflated...
8489176 Radioactive emission detector equipped with a position tracking system and utilization thereof with medical systems and in medical procedures  
A system for calculating a position of a radioactivity emitting source in a system-of-coordinates, the system comprising (a) a radioactive emission detector; (b) a position tracking system being...
8475353 Brachytherapy apparatus, systems, and methods for using them  
An applicator for delivering brachytherapy includes elongate members movable between collapsed and expanded configurations for delivering brachytherapy within a lumpectomy cavity, a vaginal cavity,...
8454488 Shielded high dose radiation catheters  
An apparatus and method for tailoring the radiation intensity about a radiation source, enabling affected zones of a cancerous tissue mass to receive full radiation dosage while limiting the...
8454489 Implant comprising radioactive seeds  
The present disclosure relates to an implant comprising at least two sheets of a biocompatible material, and at least one radioactive seed disposed between said sheets of material. The disclosure...
8449440 Apparatus for automatic tracking and identification of device components  
Embodiments of an apparatus and method to track and identify radioactive sources are described. In one embodiment, a device includes first housing for a radioactive source having a first electronic...
8444543 Apparatus and computing device for performing brachytherapy and methods of imaging using the same  
An apparatus for determining a distribution of a selected therapy in a target volume is provided. A three-dimensional ultrasound transducer captures volume data from the target volume. A computing...
8444544 Device and method for intensity modulated brachytherapy  
A radiation modulator is used with a low energy source for breast brachytherapy using a balloon-like catheter. The clinical evaluation of the patient determines the modulator's optimal...
8439867 Injection guidance system and method  
A system and method of treating urinary incontinence including a catheter and injection guide operatively disposed together. At least one needle is operatively disposed within at least one lumen...
8430804 Methods and devices for minimally-invasive extraocular delivery of radiation to the posterior portion of the eye  
Methods and devices for minimally-invasive delivery of radiation to the posterior portion of the eye including a cannula comprising a distal portion connected to a proximal portion and a means for...
8423125 Radioimaging  
Radioimaging methods, devices and radiopharmaceuticals therefor.
8421038 Methods and systems for protecting critical structures during radiation treatment  
Methods and systems are provided for protecting a critical structure during the administration of radiation treatment to a patient. A register receives proposed positions for one or more radiation...
8414467 Eyelid plaque  
An eyelid plaque and a method of using the plaque to treat eye cancers. The eyelid plaque is placed on the eyelid such that it defines an enclosure within which the radiation source resides. The...
8409069 Brachytherapy appliance and method  
A brachytherapy appliance and method utilizing a body portion or element removably positionable within a cavity of a living body, such as an oral cavity, the body portion having a shape at least...