|
Match
|
Document |
Document Title |
|
|
8143364 |
Composition made from a diisocyanate and a monoamine and process for preparing it
Process for preparing a composition by reacting a polyisocyanate, a monoalkoxy polyoxyalkylene monoamine and water. The composition and its use in making cellular products are claimed as well.
|
|
|
8119842 |
Process for synthesis of amino-methyl tetralin derivatives
Methods for producing a compound of formula k1 or k2 by reducing a dihydronapthalene amide compound of formula i with hydrogen gas in the presence of a ruthenium catalyst of formula j1 or j2...
|
|
|
8106221 |
Renin inhibitors
The present invention is directed to aspartic protease inhibitors. The present invention is also directed to pharmaceutical compositions comprising the disclosed aspartic protease inhibitors. The...
|
|
|
8071810 |
C5a receptor antagonists
The present invention is related to a compound, preferably a C5a receptor antagonist, having the following structure, R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, R13, R14, R15, R16, R17,...
|
|
|
8066974 |
Contrast agents
The present invention relates to a class of compounds and to diagnostic compositions containing such compounds where the compounds are iodine containing compounds. More specifically the iodine...
|
|
|
7893184 |
Method for producing dendritic or hyperbranched polyurethanes
Dendritic or hyperbranched polyurethanes are prepared by 1) reacting diols or polyols having at least one tertiary nitrogen atom and at least two hydroxyl groups of differing reactivity toward...
|
|
|
7709507 |
Therapeutic fluoroethyl ureas
Compounds of the formula or a pharmaceutically acceptable salt thereof or a tautomer thereof, wherein A and B are as described herein, are useful for treating conditions afflicting mammals.
|
|
|
7678812 |
Aminotetralin-derived urea modulators of vanilloid VR1 receptor
This invention is directed to vanilloid receptor VR1 ligands. More particularly, this invention relates to β-aminotetralin-derived ureas that are potent antagonists or agonists of VR1 which are ...
|
|
|
7521480 |
Aryl ureido benzoic acid derivatives and their use
This invention relates to novel aryl ureido benzoic acid derivatives useful as selective and non-competitive antagonists of the ionotropic GluR5 receptor. Due to their biological activity, the aryl...
|
|
|
7504538 |
Amide or thioamide derivatives and their use in the treatment of pain
The present invention relates to novel compounds, pharmaceutical compositions comprising the same, use of said compounds for the manufacture of a medicament for treatment of pain and disorders...
|
|
|
7339020 |
High-functionality polyisocyanates
High-functionality polyisocyanates are prepared by a process which comprises (i) preparation of an addition product (A) which contains one group which is reactive toward isocyanate and at least two...
|
|
|
7326746 |
Curable electron donor compositions
Electron donor compounds, suitable for use as adhesives or as components in adhesives, contain a carbon to carbon double bond attached to an aromatic ring and conjugated with the unsaturation in...
|
|
|
7323496 |
Compounds for treatment of inflammation, diabetes and related disorders
Novel acyl urea, thiourea, carbamate, thiocarbamate and related compounds are provided which are effective in inhibiting the cytokine-mediated inflammatory response in cultured cells, in...
|
|
|
7271288 |
Aromatic compounds
Disclosed is an aromatic compound expressed by the general formula (I), wherein A represents of a fused aromatic hydrocarbon moiety such as triphenylene, X represents a hydrogen-bonding site such...
|
|
|
7173045 |
4-aminomethyl-1-aryl-cyclohexylamine compounds
The invention concerns 4-aminomethyl-1-aryl-cyclohexylamine compounds, methods for producing same, pharmaceutical formulations containing said compounds and the use of...
|
|
|
7109375 |
Zinc and zinc alloy electroplating additives and electroplating methods
An additive for an alkaline zinc or zinc alloy electroplating bath medium, the additive comprising a random co-polymer comprising the reaction product of: (i) one or more di-tertiary amines...
|
|
|
7087676 |
Blocked polyisocyanates
Blocked polyisocyanates and one-component stoving systems containing these blocked polyisocyanates, and the preparation thereof and their use for the preparation of lacquers, paints, adhesives and...
|
|
|
7067553 |
Thiourea compounds and the pharmaceutical compositions containing the same
The present invention relates to thiourea compounds and the pharmaceutical compositions containing the same, and particularly, to novel thiourea compounds as an antagonist against vanilloid...
|
|
|
7034015 |
Aminobenzoephenones
The invention relates to a novel class of aminobenzophenones derivatives, to pharmaceutical preparations comprising said compounds, to dosage units of such preparations, to methods of treating...
|
|
|
6984647 |
Aminotetralin-derived urea modulators of vanilloid VR1 receptor
This invention is directed to vanilloid receptor VR1 ligands. More particularly, this invention relates to β-aminotetralin-derived ureas that are potent antagonists or agonists of VR1 which are ...
|
|
|
6911457 |
Diabetes imaging probes
The present invention relates to novel imaging probes and methods for using the probes in diagnostic imaging processes and other imaging processes to determine physiological functions.
|
|
|
6908957 |
Curable electron donor compounds
Electron donor compounds, suitable for use as adhesives or as components in adhesives, contain a carbon to carbon double bond attached to an aromatic ring and conjugated with the unsaturation in...
|
|
|
6852738 |
Acyl sulfamides for treatment of obesity, diabetes and lipid disorders
A class of acyl sulfamides comprises compounds that are potent ligands for PPAR gamma and generally have antagonist or partial agonist activity. The compounds may be useful in the treatment,...
|
|
|
6841701 |
Inhibitors for the blood-clotting factor Xa
The invention relates to derivatives of amidino-benzylamine, especially derivatives of 4-amidino-benzylamine, with two bonded amino acids. These derivatives represent a novel group of highly active...
|
|
|
6812250 |
Carboxamide-substituted phenylurea derivatives, process for their preparation and their use as medicaments
The invention relates to carboxamide-substituted phenylurea derivatives and their physiologically tolerated salts and physiologically functional derivatives. Compounds of the formula I in which the...
|
|
|
6803383 |
Inhibition of angiogenesis and tumor growth
Compounds which inhibit tumor growth and angiogenesis, of general formula (II) are provided. These compounds include glycyl lysine derivatives bound to a central aromatic linking core.
|
|
|
6699904 |
PPAR agonists
PPAR alpha activators, pharmaceutical compositions containing such compounds and the use of such compounds to elevate certain plasma lipid levels, including high density lipoprotein-cholesterol and...
|
|
|
6683200 |
N-substituted-N′-substituted urea derivatives and pharmaceutical compositions containing the derivatives
N-Substituted-N′-substituted urea derivatives represented by the following formula, analogs thereof or pharmaceutically acceptable salts thereof are herein provided. These compounds show a TNF-α pr...
|
|
|
6656737 |
Isocynate derivatizing agent and methods of production and use
An organic compound useful for detecting the total quantity of isocyanate in an environmental sample is provided. The compound is 9-anthrcenylmethyl-1-piperazinecarboxylate (PAC), an isocyanate...
|
|
|
6627774 |
N-deacetylthiocolchicine derivatives and pharmaceutical compositions containing them
Derivatives of N-deacetyl-thiocolchicine or of the isoster thereof of formula (I) wherein n is an integer from 0 to 8, Y is a CH2 group or, when n is 1, can also be a group of formula NH. Compounds...
|
|
|
6602903 |
Substituted heterocyclic compounds
The invention relates to compounds of formula (I): and medicinal products containing the same are useful in treating or in preventing melatoninergic disorders.
|
|
|
6531499 |
Matrix metalloproteinase inhibitors and method of using same
Peptoid compounds of Formula I and Formula II are disclosed The compounds are useful in the treatment of matrix metalloproteinase-mediated disorders.
|
|
|
6528543 |
Urea derivatives
Glucokinase activating compounds of the formula wherein R1 and R2 are independently hydrogen, halo, amino, nitro, cyano, sulfonamido, lower alkyl, perfluoro-lower alkyl, lower alkyl thio,...
|
|
|
6492370 |
Urea derivatives and pharmaceutical compositions thereof
Objects of the present invention are to create compounds having urea structure as basic structure and having a sulfur atom and an amide bond in side chains and to find pharmacological effects...
|
|
|
6482804 |
Compositions and methods for delivery of genetic material
A soluble ionic complex is formed by an aqueous mixture of a benzylammonium group-containing surfactant and a polynucleic acid sequence. When the mixture forms a vesicular complex, the sequence is...
|
|
|
6423870 |
Tricyclic compounds, preparation method and pharmaceutical compositions containing same
The invention concerns compounds of formula (I) in which: A forms a tricyclic system of formula A1, A2, A3 or A4; R1 represents a hydrogen atom, an alkyl, hydroxy, alkoxy or oxo group; (R2)m and...
|
|
|
6410573 |
2,5-substituted benzolsulfonylureas and thioureas methods for the production thereof use thereof and pharmaceutical preparations containing the same
Novel 2,5-substituted benzolsulfonyl ureas and thioureas of formula (I) as illustrated in the disclosure. The compounds are useful active ingredients for medicaments. The compounds of formula (I)...
|
|
|
6391917 |
Dialkyl ureas as calcitonin mimetics
Dialkyl urea compounds are described which act as calcitonin mimetics. These compounds are useful in the treatment of diseases which are associated with bone resorption. The calcitonin mimetics of...
|
|
|
6307001 |
Curable hybrid electron donor compounds containing vinyl ether
Hybrid electron donor compounds, suitable for use as adhesives or as components in adhesives, contain a carbon to carbon double bond attached to an aromatic ring and conjugated with the...
|
|
|
6303269 |
Dye precursor, photosensitive material containing dye precursor and method for forming color image
A dye precursor represented by the following formula (I): ##STR1##wherein A1 and A2 each represents an atomic group to form a coupler residue together with --N(R5)R6 and the carbon atom to which A1...
|
|
|
6300456 |
Compounds with electron donor and electron acceptor functionality
Compounds containing both electron donor and electron acceptor functionality are suitable for use in adhesives. The electron donor group is a carbon to carbon double bond attached to an aromatic...
|
|
|
6294694 |
Matrix metalloproteinase inhibitors and method of using same
Peptoid compounds of Formula I and Formula II are disclosed ##STR1##The compounds are useful in the treatment of matrix metalloproteinase-mediated disorders.
|
|
|
6136942 |
Latent amino groups and isocyanate groups comprising polyurethane prepolymers, method for their production and their use
A one-component polyurethane composition is described that comprises a latent curing agent bonded to the prepolymer, from which curing agent aldehyde is liberated upon curing. Said aldehyde...
|
|
|
6127414 |
NPY antagonists
There is provided pharmaceutically useful compounds of formula I, ##STR1## wherein Ar1, R1, R2, R3, R4, R5 and R6 have meanings given in the description, which are useful as antagonists of...
|
|
|
6127423 |
Phenylamidine derivatives, a process for preparing the same and their use as medicaments
The invention relates to new phenylamidine derivatives, processes for preparing them and their use as pharmaceutical compositions. The phenylamidines according to the invention correspond to the...
|
|
|
6127575 |
Process for preparing n,n'-disubstituted urea using selenium-based catalyst
A process is disclosed for preparing N,N'-disubstituted urea by reacting an amine and CO/O2 mixture gas in the presence of a catalyst system comprising at least one selenium compound selected from...
|
|
|
6114493 |
Phosgenated oxime resins and their preparation
This invention relates to methods for preparing novel, solid-phase transfer reagents, specifically phosgenated oxime resins and non-symmetrical ureas, that are useful as supports in combinatorial...
|
|
|
6048877 |
Tetralone derivatives as antiarrhythmic agents
Tetralone derivatives of the formula ##STR1## where R1 is halo, alkyl, alkenyl, alkynyl, cycloalkyl, aryl, (aryl)alkenyl, (aryl)alkynyl, alkoxy, O-alkenyl, O-aryl, O-alkyl(heterocyclo),...
|
|
|
6040339 |
Urea derivatives having ACAT inhibitory activity, their preparation and their therapeutic and prophylactic use
Compounds of formula (I): ##STR1## wherein: R1 is alkyl; R2a, R2b, R2c and R2d are the same or different and each is hydrogen, optionally substituted alkyl or various other organic groups; R3 is...
|
|
|
5902899 |
Process for preparing 1, 3-disubstituted urea
Process for preparing 1,3-disubstituted urea of the formula: ##STR1## wherein R5 is the same as or different from R6, and each of R5 and R6 is independently linear or branched, alkyl of 1-20 carbon...
|