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7605290 |
Processes for the synthesis of O-desmethylvenlafaxine
The present invention describes processes for the preparation of O-desmethylvenlafaxine and tridesmethylvenlafaxine, which may be used as an intermediate in preparing O-desmethylvenlafaxine.
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7528283 |
Process for preparing diamines and polyamines from the diphenylmethane series
The invention provides an improved process for preparing diamines and polyamines from the diphenylmethane series by reacting aniline and formaldehyde in the presence of an acid catalyst, the...
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7456319 |
Para-alkylation of aromatic primary amines
A method is provided for producing primarily para alkyl aromatic amines by alkylating a primary aromatic amine with an olefin in the presence of an acid activated clay.
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7435854 |
Methods for preparing O-desmethylvenlafaxine
The present invention provides an efficient method of making O-desmethyl-venlafaxine.
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7390927 |
Process for preparing 3-aminophenylacetylenes
A process for preparing a 3-aminophenylacetylene compound of formula (5), including: a) reacting a 3-haloaniline compound of formula (1) with an acetylene compound of formula (2) in the presence of...
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7378554 |
Ring alkylation of aniline or an aniline derivative using ionic liquid catalysts
A process for ring-alkylating aniline or an aniline derivative in which aniline or an aniline derivative is reacted with an alkylating agent in the presence of an ionic liquid which includes a...
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7342133 |
Substituted amino compounds as 5-HT/NA uptake inhibitors
The invention relates to substituted amino compounds, to processes for their preparation, to pharmaceutical formulations containing these compounds and to the use of these substances in the...
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7253321 |
Process for the preparation of polyamines of the diphenylmethane series at a low degree of protonation
The invention provides a process for the preparation of polyamines of the diphenylmethane series. This process comprises
a) reacting aniline and formaldehyde in a molar ratio of 1.5:1 to...
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7145038 |
Alkylation of a diphenylamine compound in ionic liquid
A process for alkylation of a diphenylamine compound in an ionic liquid. The use of an ionic liquid permits convenient separation of the alkylated reaction product from the reaction mixture.
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7005553 |
Method for the nitration of phenolic compounds
A method for the regioselective ortho-directed nitration of phenolic compounds useful for the preparation of ortho-nitro-phenols according to formula (I) is described.
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6639102 |
Process for producing polyisocyanates of the diphenyl methane series having a reduced color value
Polyisocyanates of the diphenyl methane series having reduced color values are obtained by a) reacting aniline and formaldehyde in the presence of an acid catalyst to form a polyamine, b)...
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6624201 |
HIGH PURITY (1R,2S,4R)-(−)-2-&lsqb (2′-&lcub N,N-DIMETHYLAMINO&rcub -ETHOXY)&rsqb -2-&lsqb PHENYL&rsqb -1,7,7 -TRI-&lsqb METHYL&rsqb -BICYCLO &lsqb 2.2.1&rsqb HEPTANE AND PHARMACEUTICALLY ACCEPTABLE ACID ADDITION SALTS THEREOF AND A PROCESS FOR THE PREPARATION OF THESE COMPOUNDS AS WELL AS MEDICAMENTS CONTAINING 1 OR MORE OF THESE COMPOUNDS AND THEIR USE
The invention relates to high purity (1R,2S,4R)-(−)-2-[(2′-{N,N-dimethylamino}-ethoxy)]-2-[ph
enyl]-1,7,7-tri-[methyl]-bicyclo[2.2.1]heptane and pharmaceutically acceptable acid addition salts...
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6566571 |
Method of producing biaryls
Process for preparing monofunctional, bifunctional and/or polyfunctional biaryls of the formula (I) Ar—Ar′ (I) by reacting haloaromatics of the formula (II) Ar—X (II) with boron compounds...
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6392111 |
Method for producing olefins
Olefins containing aromatic substituents are synthesized without the addition of phosphonium salts or phosphanes with the aid of a Pd II compound as a catalyst in the presence of...
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6355839 |
Alkylation of diphenylamine with polyisobutylene oligomers
A process for preparation of alkylated diphenylamine antioxidant which comprises alkylating diphenylamine with a polyisobutylene in the presence of a clay catalyst, wherein the polyisobutylene has...
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6315925 |
Nonylated diphenylamines
The invention relates to a mixture of nonylated diphenylamines, especially dinonylated diphenylamines, and to a technically advantageous methodological process for the preparation of that mixture...
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6215035 |
Process for the preparation of aralkylated aromatic compounds using heterogeneous catalyst
The invention relates to a process for the preparation of aralkylated aromatic compound with both small and large size aralkylating agents; wherein the catalyst used is heterogeneous solid catalyst...
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6204412 |
Method of manufacturing alkylated diphenylamine compositions and products thereof
A method of manufacturing an alkylated diphenylamine composition to generate an alkylated diphenylamine composition with relatively low amounts of unsubstituted diphenylamine, based on the total...
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6028225 |
Method of making hydroxy-substituted hydroxylamines and color developers containing same
Hydroxy-substituted hydroxylamine antioxidants can be prepared by reacting hydroxylamine or a mono-substituted hydroxylamine, in free base form, with an epoxide. The antioxidant reaction product...
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5962739 |
Process for the preparation of N,N- dialkylaminophenyl alkanols
The present invention provides a process for the production of an N,N-dialkylaminophenyl alkanol having the formula: ##STR1## in which R 1 and R 2 , independently, are C 1 -C 4 alkyl, R 3 is...
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5902902 |
Process for the industrial preparation of aminoacetylenes
A process for the preparation of 3-aminophenylacetylene derivatives of formula: ##STR1## wherein R 1 is as defined in the disclosure ##STR2## wherein Y is as defined in the disclosure ...
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5817831 |
Alkylation of aromatic amines using a heterpoly catalyst
Aliphatic hydrocarbyl-substituted aromatic amines are prepared by reacting an aromatic amine and an aliphatic hydrocarbylating agent, such as an olefin, in the presence of a heteropolyacid catalyst...
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5750787 |
Liquid alkylated diphenylamine antioxidant
A process for monoalkylating diphenylamine using a clay catalyst is disclosed which results in a reaction product having substantial amounts of desirable monoalkylated diphenylamine and minimal...
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5734084 |
Synthesis of alkylated aromatic amines
An improved method for making alkylated aromatic amines is disclosed. The method includes a new alkylating catalyst system comprising an aromatic amine alkylating catalyst and a non-catalyst solid...
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5659084 |
Processes and intermediates for the preparation of 2-substituted benzaldehydes
Processes for preparing 2-substituted benzaldehydes of general formula (I), wherein: R 1 is CH 2 CH 2 --(L 1 ) p --(CH 2 ) q --(L 2 ) r --CH 2 --(T) 2 --Z; L 1 and L 2 are independently...
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5633407 |
Process for preparing substituted aromatic amines
A process for preparing substituted aromatic azo compounds is provided which comprises contacting a nucleophilic compound and an azo containing compound in the presence of a suitable solvent...
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5599995 |
Electrophotographic photoconductor comprising pyrenylamine derivative, the pyrenylamine derivative, intermediate for preparation thereof, and method for preparing the pyrenylamine derivative and the intermediate
An electrophotographic photoconductor comprises an electroconductive substrate and a photoconductive layer formed thereon comprising as an effective component at least one pyrenylamine derivative...
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5571453 |
Stabilized polyether polyol and polyurethane foam obtained therefrom
A stabilizer composition useful as an additive for polyether polyols, particularly those employed in the manufacture of polyurethane foams, is provided which comprises a...
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5520848 |
Mixtures and compositions containing phenothiazines
A mixture containing phenothiazines which is obtainable by reacting a mixture of diphenylamines comprising TBL ______________________________________ 1 to 5% by weight a) diphenylamine of 8 to 18%...
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5466871 |
Process for preparing nitroaniline derivatives
A process for preparing a nitroaniline derivative comprising a step of reacting an aromatic nitro compound with an O-alkylhydroxylamine or a salt thereof in the presence of a base and optionally a...
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5436371 |
Process for preparing p-nitroaromatic amides and products thereof
A process for preparing p-nitroaromatic amides is provided which comprises contacting a nitrile, nitrobenzene, a suitable base and water in the presence of a suitable solvent system to form a...
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5283363 |
Process for the preparation of (hetero)arylalk(en/in)ylamines and (hetero)arylalkinylamines
The invention relates to a new process for the preparation of (hetero)arylalk(en/in)ylamines of the formula (I) ##STR1## in which A represents ethane-1,2-diyl (ethylene, dimethylene, --CH 2 --CH 2...
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5276194 |
Polyfluoroalkylation of aromatic compounds
A process is provided for the catalytic perfluoroalkylation of aromatic compounds, wherein a perfluoroalkyl iodide or mixture of iodides is reacted with an aromatic compound in the presence of an...
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5243116 |
Alkylation of aromatic compounds
Alkylated benzenes such as ethylbenzene and cumene are produced by alkylation and/or transalkylation in the presence of an acidic mordenite zeolite catalyst having a silica/alumina molar ratio of...
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5214211 |
Alkylation of diarylamines with olefins using rare earth modified pillared clays
Rare earth pillared clays, and especially cerium and lanthanum aluminum chlorohydrite pillared clays, are quite effective catalysts in the alkylation of diaryl amines at temperatures in the range...
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5214186 |
Process for the preparation of arylidine dyes using an active methylene compound
A process for the preparation of arylidene dyes comprises the reaction of an aromatic amine with an enolate salt of a formylated active methylene compound in the presence of a sulfonyl halide...
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5171915 |
Alkylaromatic lubricants from alpha-olefin dimer
It is disclosed that aromatic compounds can be alkylated with mono-olefinic HVI-PAO dimer in contact with an acidic catalyst to produce novel alkylated aromatic compositions. It has been found that...
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5171890 |
Process for preparing methyl- and ethyl-substituted primary anilines
A process is disclosed for the preparation of methyl- and ethyl-substituted anilines by contacting anilines of specified formula at about 250°-525° C. and about 10 kPa-10 MPa of pressure in the...
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5132475 |
Quaternary ammonium fluoride catalyzed halogenation of carbon acids
A process is disclosed for chlorinating, brominating and/or iodinating an organic substrate containing both a single acidic hydrogen atom and at least one electron withdrawing group attached to the...
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5124483 |
Ortho-alkylation of aromatic amines
Aromatic diamines, such as toluenediamine, are alkylated in the ortho position by heating the diamine in the presence of an aluminum alloy, aluminium chloride and, optionally, zinc, and then...
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5087754 |
Process for the preparation of N,N-dialkylaniline
N,N-dialkylanilines can be prepared by reacting the anilines on which they are based with lower alcohols or with the corresponding ethers, at an increased temperature in the gas phase in the...
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5081302 |
Selective C-alkylation of aniline in the presence of zeolite catalysts to para-aniline
The selective ring-alkylation of anilines comprising providing a mixture of a lower alkanol and an aniline, exposing said mixture to a temperature of from 300° C. to 500° C., preferably from...
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5068435 |
Ortho-alkylated aromatic amines via gamma alumina catalyst
This invention relates to a process for producing ring alkylated aromatic amines. In the process an aromatic amine is reacted with an olefin using gamma alumina as a catalyst. Under the conditions...
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5057625 |
Selective alkylation process
Mono-ar-tert-butyl toluenediamine is selectively made by heating a mixture of toluenediamine and an aluminum halide of the formula R n AlX 3 -n or R 3 Al 2 X 3 wherein n is 0, 1 or 2 and R is...
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5043469 |
Process for preparing 5-substituted aminophenols
Process for the introduction of functional or functionalizable substituents para to the amino group in 2-aminophenols and 3-aminophenols. The process proceeds in one step, with substitution...
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5026912 |
Alkylation of aromatic amines over thermally pretreated zeolites
A process for selectively producing ortho-alkylated aromatic amines in high selectivity relative to N-alkylated aromatic amines. The process comprises reacting an aromatic amine, having at least...
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5001263 |
Formation of ortho-alkylated aromatic amines from N-alkylated aromatic amines
This invention relates to a process for producing ring alkylated aromatic amines where the alkyl substituent is ortho to the amino group by reacting an N-alkylated aromatic amine with a C 2 -10...
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RE33549 |
Process for preparing a mixture of methyl- or ethyl-substituted primary anilines
A process is disclosed for preparing an isomeric mixture of a monomethyl-, dimethyl- or monoethyl-substituted aniline consisting essentially of contacting at least one of said anilines with a...
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4973759 |
Process for the isolation of alkylated aromatic amines
Alkylated aromatic amines can be isolated from crude catalyst-containing mixtures of these with olefins by a procedure in which in general equivalent amounts of an inorganic base and water are...
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4967001 |
Alkylation of toluenediamine and para-phenylenediamine with isobutylene in the presence of acidic, crystalline molecular sieves
This invention relates to an improvement in a process for producing tert-butyl-derivatives of aromatic amines, e.g., para-phenylenediamine and toluenediamine by the reaction of isobutylene with the...
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