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7605137 |
Combination therapy comprising cloretazine
This invention provides a method for treating tumor in a subject comprising administering to the subject an effective amount of: (1) VNP40101M, or its equivalent; and (2) a nucleoside, or a...
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7465828 |
Method for preparing hydrazodicarbonamide using biuret as starting material
The method for preparing hydrazodicarbonamide (HDCA) using biuret as a starting material is disclosed. The method comprises the steps of; obtaining metal monohalobiuret salt by reacting a biuret...
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7456314 |
Partially fluorinated ionic compounds
Partially fluorinated ionic compounds are prepared. They are useful in the preparation of partially fluorinated dienes, in which the repeat units are cycloaliphatic.
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6943179 |
Biurethane derivatives
Novel compounds of the formula I in which X, Y, Z, R, R 1 , R 2 and R 3 are as defined in Patent Claim 1 , are inhibitors of coagulation factor Xa and can be employed for the prophylaxis and/or...
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6635785 |
Method for synthesizing hydrazodicarbonamide
A method for synthesizing hydrazodicarbonamide (HDCA) by a reaction of monohalobiuret metal salt having the formula 1 or 2, which is derived from biuret, and ammonia, wherein M is a metal and X is...
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6515177 |
Method of coating materials and materials formed thereby
A method of forming a methylol urea prepolymer and a particle coated in with the prepolymer. The method involves providing a source of methylol urea and a source of aldehyde and reacting the urea...
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6472560 |
Process for preparing hydrazodicarbonamide via ketimines
The present invention relates to a novel process for preparing hydrazodicarbonamide (HDC) that is, after oxidation to azodicarbonamide (ADC), used industrially as a polymer auxiliary.
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6441231 |
Optically active quarternary ammonium salt with axial chirality, method for producing thereof, and application thereof for asymmetric synthesis of α-amino acid
A novel optically active quarternary ammonium salt with an axial chirality is provided. The quarternary ammonium salt can act as a phase-transfer catalyst to convert glycine derivatives into...
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6362359 |
One-component thermoset coating compositions
The present invention relates to compounds containing modified hydrazide groups and corresponding to formula I wherein R represents the residue obtained by removing the isocyanate groups from a...
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6331542 |
Protease inhibitors
The present invention provides compounds which inhibit proteases, including cathepsin K, pharmaceutical compositions of such compounds, and methods for treating diseases of excessive bone loss or...
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6284777 |
Carbohydrazide protease inhibitors
The present invention provides compounds which inhibit proteases, including cathepsin K, pharmaceutical compositions of such compounds, and methods for treating diseases of excessive bone loss or...
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6281211 |
Substituted semicarbazides and the use thereof
This invention is related to substituted semicarbazides represented by Formula (I) or a pharmaceutically acceptable salt or prodrug thereof, wherein: R 1 and R 2 are independently hydrogen,...
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6114493 |
Phosgenated oxime resins and their preparation
This invention relates to methods for preparing novel, solid-phase transfer reagents, specifically phosgenated oxime resins and non-symmetrical ureas, that are useful as supports in combinatorial...
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5858327 |
Hydrazino-type N.sub.2 S.sub.2 radionuclide chelating compounds
Radionuclide chelating compounds are provided for conjugation to targetting molecules such as proteins, peptides or antibodies. The resulting labelled targetting molecules may be used in diagnosis...
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5837874 |
Hydrazide intermediates
The present invention relates to a triazole compound represented by the formula (1): ##STR1## wherein R 1 represents a lower alkyl group which may have a substituent; R 2 and R 3 represent...
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5659064 |
Hydrazone intermediates
The present invention relates to a triazole compound represented by the formula (1): ##STR1## wherein R 1 represents a lower alkyl group which may have a substituent; R 2 and R 3 represent...
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5637619 |
Antitumor 2-aminocarbonyl-1, 2-bis(methylsulfonyl)-1-(substituted)hydrazines
The present invention relates to novel 2-aminocarbonyl-1,2-bis(methylsulfonyl)-1-(2-chloroethyl)hyd
razines and 2-aminocarbonyl-1,2-bis(methylsulfonyl)-1-methylhydrazines, and their use to treat...
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5574140 |
Hydrazino-type N.sub.2 S.sub.2 chelators
Radionuclide chelating compounds are provided for conjugation to targetting molecules such as proteins, peptides or antibodies. The resulting labelled targetting molecules may be used in diagnosis...
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5283248 |
Amino substituted pyrimido[1,6-2]benzimidazoles
The present invention relates to novel substituted pyrimidobenzimidazole derivatives of the formula ##STR1## wherein the substituents are as described in the specification, and pharmaceutically...
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5117057 |
Insecticidal N' substituted-N-N'-disubstituted-hydrazines
This invention relates to insecticidal compositions containing N'-substituted-N,N'-disubstitutedhydrazines, methods of using such compositions and N'-substituted-N, N'-disubstitutedhydrazines....
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5041545 |
2-hydroxybenzophenone hydrazides and derivatives thereof
Hydrazide functionalized 2-hydroxybenzophenone ultraviolet light and heat stabilizers and derivatives are disclosed having the general formula: ##STR1## wherein R 1 , R 2 , R 3 , R 4 , R 5 , R 6 ,...
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4973618 |
Oligomeric semicarbazide additives for spandex
Oligormeric polyether/urethanes with semicarbazide end-groups protect spandex fibers from discoloration in atmospheric fumes and/or light. The oligomers are prepared from polyether glycols,...
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4482738 |
Process for preparing semicarbazide hydrochloride
A process for preparing semicarbazide hydrochloride comprising the steps: (a) reacting an aqueous hydrazine solution with urea at a temperature from about 80° C. to about 130° C. and at a mole...
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4414413 |
1,2-Di[N,N-Bis(2-fluoro-2,2-dinitroethyl)carbamyl]hydrozine
N,N,N',N'-tetrakis(2-fluoro-2,2-dinitroethyl) oxamide, ##STR1## which is prepared by the following reaction sequence ##STR2## N,N,N',N'-tetrakis(2-fluoro-2,2-dinitroethyl) oxamide is a high...
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4331680 |
Pesticidal compounds, compositions and methods
Novel compounds are described which are substituted benzophenone hydrazones. They have pesticidal activity, especially against insects and acarids, and pesticidal compositions and methods are...
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4317928 |
N,N,N',N'-Tetrakis(2-fluoro-2,2-dinitroethyl) oxamide and a method of preparation thereof
N,N,N', N'-tetrakis(2-fluoro-2,2-dinitroethyl) oxamide, ##STR1## which is prepared by the following reaction sequence ##STR2## N,N,N',N'-tetrakis(2-fluoro-2,2-dinitroethyl) oxamide is a high...
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4294972 |
1,2-Disubstituted oxo triazolidine
Compounds of the formula (I): ##STR1## wherein n is 3 to 5; Y is --CH 2 --CH 2 , --CHCH-- or C.tbd.C--; L is O or S; R 1 is C 1 -4 alkyl; R 2 is hydrogen, C 1 -4 alkyl or phenyl; ...
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4176135 |
Process for preparing hydrazodicarbonamide
Hydrazodicarbonamide is prepared by reacting a compound represented by ##STR1## with urea while the former is being continuously or intermittently introduced into the reaction system and while the...
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4175200 |
N,N-Disubstituted sulfonyl hydrazines
N,N'-disubstituted sulfonyl hydrazine with the following structural formula are disclosed: R(SO 2 NR 1 NHR 2 ) n wherein the R 1 and R 2 groups are the same or different and are either --COOR...
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4164611 |
Aromatic sulfonyl hydrazides and semicarbazides as chemical blowing agents
Aromatic sulfonic acid hydrazides and semicarbazides having a sterically hindered phenol group are usable as blowing agents in the manufacture of foamed plastics articles. On heating to about 200...
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4133832 |
Blowing agents -bis(hydrocarbylsulfonyl) carbohydrazides
Hydrocarbylsulfonyl carbohydrazides of the following structural formulae are disclosed for use as blowing agents: ##STR1## The compounds wherein the R groups are alkyl are novel, as are the...
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4104301 |
Synthesis of sulfonyl semicarbazides
A new synthetic route to sulfonyl semicarbazides (sulfonyldiazanecarboxamides) and sulfonyl-1,2-diazanedicarboxyamide wherein a substituted 1,2-diazenedicarboxamide is reacted with a salt of a...
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4066639 |
Benzene-sulfonyl semicarbazides and process for preparing them
A benzene-sulfonyl semicarbazide of the formula ##STR1## wherein R is such as phenyl and substituted phenyl, cyclohexyl or alkyl, Y is -CH 2 CH 2 - or ##STR2## is alkylene-imino of 3 to carbon...
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4049712 |
Method for manufacturing hydrazodicarbonamide
This invention relates to a method for preparing hydrazodicarbonamide ##STR1## which comprises reacting urea, sulfuric acid, water and an azine or a solution containing an azine of the formula...
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4029702 |
Oil-soluble bicarbamamide compounds
The oil-soluble azo compounds of this invention are useful as dispersants, corrosion inhibitors and anti-wear agents in lubricating oil and fuel compositions. The predominant oil-soluble azo...
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4024129 |
Process for the preparation of heterocyclic compounds
A process for the preparation of acylamido derivatives by reaction of a compound of the formula Z - N = C = O, wherein Z is an optionally substituted alkyl-, aryl- (preferably phenyl or naphthyl)...
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4012360 |
Bis-salicyloyl-dicarboxylic acid dihydrazides as stabilizers for polyolefines
New bis-salicyloyl-dicarboxylic acid dihydrazides are stabilizers for polyolefines. They are prepared by reacting a salicylic acid hydrazide with a dicarboxylic acid chloride or a dicarboxylic acid...
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3969466 |
Preparation of hydrazodicarbonamide
A process for preparing hydrazodicarbonamide directly from a ketazine and urea in water without any acid catalyst according to the following reaction is disclosed. ##EQU1## wherein the R groups may...
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3933909 |
Method for producing sulfonyl semicarbazides
A new synthetic route to sulfonyl semicarbazides wherein an azobisformamide is reacted with a free sulfinic acid.
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3903157 |
Sulfonyl semicarbazides
Organic sulfonyl semicarbazides are prepared by reacting a salt of a sulfinic acid with azodicarbonamide in the presence of water. E.g., reaction of sodium p-toluene sulfinate with azodicarbonamide...
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3856786 |
SULFONYLDIISOCYANATE ADDUCTS
Cyclic adducts of the structure ##SPC1## And linear derivatives of the structure ##SPC2## Where R and R' are organic radicals and X is oxygen, nitrogen or sulfur, exhibit bacteriostatic and...
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3843661 |
BENZENE-SULFONYL SEMICARBAZIDES
Benzene-sulfonyl semicarbazides having hypoglycemic properties and corresding to the general formula ##SPC1## Wherein R represents A. phenyl which may be substituted once or twice by substituents...
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3668076 |
DIAGNOSTIC AGENT
Diagnostic agent suitable for use in carrying out rapid analytical determinations of the presence and/or concentration of hydroperoxides, substances which react with the liberation of hydrogen...
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3655391 |
AZODICARBONAMIDE FOG INHIBITORS
Azodicarbonamides, preferably having the general formula wherein R 1 , R 2 , R 3 and R 4 individually are hydrogen, alkyl, aryl, or heterocyclic groups, or wherein the pairs of groups R 1 - R 2 ...
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3626007 |
HYDRAZODICARBOXYLIC AMIDES AND HERBICIDES CONTAINING SAME
Substituted hydrazodicarboxylic amides, particularly those substituted by phenyl or cycloalkyl, and methods for controlling unwanted plant growth with said compounds.
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3546234 |
BENZENE-SULFONYL-SEMICARBAZIDES
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3366622 |
Oxidation of hydrazoamides to azoformamides
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3352909 |
Novel 4-(organosulfonyl) semicarbazides
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3344182 |
Process for producing organic sulfonyl semicarbazides
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3330857 |
N-carbazoylamino acid intermediates for polypeptides
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