Patents in Class 564/183

Matches 1 - 50 out of 216

1 2 3 4 5 >

Match	Document	Document Title
1	7618996	Diaryl ether derivatives and uses thereof Compounds of Formula (I) that act as antagonists at the mu, kappa and/or delta opioid receptors and therefore useful in the treatment of diseases, conditions and/or disorders that benefit from such...
2	7476764	Phenylcarboxyamides as beta-secretase inhibitors There is provided a series of novel phenylcarboxyamides of Formula (I) or a stereoisomer; or a pharmaceutically acceptable salt thereof, wherein R 1 , R 2 , R 3 , X and Y as defined herein,...
3	7297818	Adamantane derivatives The invention provides adamantane derivatives of formula (I), a process for their preparation, pharmaceutical compositions containing them, a process for preparing the pharmaceutical compositions,...
4	7235692	*WITHDRAWN PATENT AS PER THE LATEST USPTO WITHDRAWN LIST* Adamantane derivatives The invention provides adamantane derivatives of formula (I), a process for their preparation, pharmaceutical compositions containing them, a process for preparing the pharmaceutical compositions,...
5	7230018	Substituted propane-1,3-diamine derivatives and the pharmaceutical use thereof Substituted propane-1,3-diamine derivatives, methods for producing such derivatives, and medicaments and pharmaceutical compositions containing such derivatives useful for the treatment or...
6	7012160	Fluorine-containing acetophenone derivative, surface layer material containing the same as photo initiator, article with composite hard coat layer, and method for forming composite hard coat layer The present invention provides a new fluorine-containing acetophenone derivative useful as a photo initiator, and a surface layer material containing the fluorine-containing acetophenone...
7	6936736	Amide derivative A compound of the formula: wherein Ar is optionally substituted phenyl, etc.; n is 0, 1 or 2; R 1 is hydogen atom, optionally substituted alkyl, etc.; R 2 and R 3 are independently...
8	6881754	Adamantane derivatives The invention provides adamantane derivatives of formula (I), a process for their preparation, pharmaceutical compositions containing them, a process for preparing the pharmaceutical compositions,...
9	6790965	Combinatorial dihydrobenzopyran library Combinatorial libraries are disclosed which are represented by Formula I: (T′—L) q —Ŝ—C(O)—L′—II′ I wherein: Ŝ is a solid support; T′—L— is an identifier residue; and...
10	6596902	Process for the preparation of 2-aryl-5- (perfluoro-alkyl)pyrrole compounds from N-&lsqb 1-chloro-1-(perfluoroalkyl)methyl&rsqb arylimidoyl chloride compounds There is provided a process for the preparation of 2-aryl-5-(perfluoroalkyl)pyrrole compounds from N-[1-chloro-1-(perfluoroalkyl)methyl]arylimidoyl chloride compounds. The...
11	6566403	N-acetonylbenzamide fungicides This invention relates to new compositions comprising predominantly one enantiomer of an N-acetonylbenzamide fungicide, methods of preparing N-acetonylbenzamides, and their use as fungicides.
12	6551761	Photoactivatable nitrogen-containing bases based on α-ammonium ketones, iminium ketones or amidinium ketones and aryl borates This invention relates to α-ammonium ketones, iminium ketones or amidinium ketones in the form of their tetraaryl- or triarylalkylborate salts which can be photochemically converted into amines,...
13	6506733	Compounds and compositions as protease inhibitors Compounds of the formula: are provided, and are useful as cysteine protease inhibitors, particularly in the treatment of diseases such as osteoporosis or autoimmune disorders in which cathepsins...
14	6486349	Amide therapeutics and methods for treating inflammatory bowel disease Disclosed are methods for treating or preventing inflammatory bowel disease (IBD) using amide and related compounds. Pharmaceutical compositions containing amide compounds which are useful for the...
15	6441233	Process for the preparation of aromatic carboxylic acid amides A process for the preparation of primary aromatic carboxamides by the carbonylation of an aromatic compound, which contains at least one leaving group, with carbon monoxide, in the presence of a...
16	6436925	Substituted benzamides, their production and their use as cysteine protease inhibitors Benzamides of the formula I and its tautomeric forms, possible enantiomeric and diastereomeric forms, E and Z forms, and possible physiologically tolerated salts, in which the variables have the...
17	6423870	Tricyclic compounds, preparation method and pharmaceutical compositions containing same The invention concerns compounds of formula (I) in which: A forms a tricyclic system of formula A 1 , A 2 , A 3 or A 4 ; R 1 represents a hydrogen atom, an alkyl, hydroxy, alkoxy or oxo group; (R...
18	6420605	Benzamidoxim derivatives, intermediate products and methods for preparing and using them as fungicides The invention relates to benzamidoxim derivatives of formula (I) wherein the substituents have the following meanings: R 1 represents difluoromethyl or trifluoromethyl, R 2 represents hydrogen or...
19	6391175	Carbonate ionophore with improved selectivity The invention pertains to a novel ionophore having the general structure: wherein R 1 , R 2 , R 3 and R 4 are independently straight or branched chain alkyl having 4 to 12 carbon atoms or the...
20	6339157	Synthesis of carboxamides from the catalyzed reaction of aldehydes and amines Aldehydes are catalytically combined with amines to form carboxamides in one step using an oxidant and a metal-ligand complex or metal/ligand composition.
21	6326517	Method of producing benzamides A method of producing benzamides represented by the following general formula (1): ##STR1## where R is trifluoromethyl group, trifluoromethyloxy group, halogen (fluorine, chlorine, bromine or...
22	6323315	Dolastatin peptides The present invention provides compounds of the formula ##STR1## where R 1 -R 5 are each, independently, a hydrogen atom or a normal or branched C 1 -C 6 -alkyl group; A is a methionyl,...
23	6313302	Pyrrolidinyl and pyrrolinyl ethylamine compounds as kappa agonists A compound of the following formula: ##STR1## and the salts thereof, wherein A is hydrogen, halo, or hydroxy; the broken line represents an optional double bond with proviso that if the broken line...
24	6235789	Benzocycloalkene compounds, their production and use A compound of the formula ##STR1## wherein R 1 and R 2 are H, a hydrocarbon group or a heterocyclic group, or R 1 and R 2 are combinedly a spiro ring; R 3 is a hydrocarbon group, a substituted...
25	6177463	Oxime derivatives and their use as pesticides The invention relates to new oxime derivatives, to a plurality of processes for their preparation, and to their use as pesticides.
26	6166273	Processes for fluorinating aromatic ring compounds A process is provided for increasing the fluorine content of benzene or pyridine rings which are optionally substituted with from 1 to 3 inert substituents. The process involves (a) contacting the...
27	6083987	Phenylenediamine derivative, radical scavenger, brain-infarction depressant, and brain-edema depressant A phenylenediamine derivative or a salt thereof in accordance with the present invention is expressed by the following formula 1: ##STR1## wherein A represents a group expressed by --CO--, --CH 2 ...
28	6066766	Process for the preparation of 4-chlorobiphenyls 4-Chlorobiphenyls are prepared by reacting a haloaromatic with an aryl Grignard compound, where halogen is chlorine, bromine or iodine, in the presence of a palladium catalyst of the formula (IV)...
29	6001880	Alkylenediamine derivative, anti-ulcer drug, and antibacterial drug An alkylenediamine derivative or a salt thereof expressed by the following formula 1: ##STR1## wherein each of R 1 and R 2 represents a lower alkyl group, and W represents a group expressed by...
30	5994507	Method for binding albumin and means to be used in the method A method for binding albumin by contacting an aqueous liquid containing an albumin with an albumin-binding compound is selected from albumin-binding compounds containing the scaffold...
31	5965744	Ortho-substituted benzoylguanidines, including composition and methods of using them The present invention relates to ortho-substituted benzoylguanidines of the formula I, defined in the specification. The invention also embraces processes for making these compounds, as well as...
32	5869531	Fluoroalkyl substituted benzoylguanidines Disclosed are 4-(2'-trifluoromethylethyl)benzoylguanidine and 3-methylsulfonyl-4-(2'-trifluoromethylethyl)benzoylguanidine . Also disclosed are pharmaceutical compositions and the use of the...
33	5856574	Ortho-subsituted benzoylguanidines, process for their preparation, their use as a medicament or diagnostic, and medicament containing them Ortho-substituted benzoylguanidines, process for their preparation, their use as a medicament or diagnostic, and medicament containing them Ortho-substituted benzoylguanidines of the formula I...
34	5824821	Process for the preparation of iodinated contrast agents and intermediates therefor The invention provides a process for the production of a 2,3-dihydroxypropylamino compound, said process comprising the reaction steps of: (i) obtaining an allylamino compound; (ii)...
35	5777181	2, 4, 5-trihalogeno- and 2, 3, 4, 5-tetrahalogenobenzene derivatives 2,4,5-Trihalogenobenzene derivatives of the formula ##STR1## in which R is --COOH, --COCl, --COF, --CN, --CONH 2 , --CH 2 OH, --CH 2 Cl, --CHCl 2 , --CCl 3 or --CHO, R 1 is H, Cl or F, and ...
36	5756834	Process for preparing fluorinated aromatics It is known to prepare fluorinated aromatic compounds of the formula I ##STR1## in which X, Y and Z can have the meaning specified in the description, by reacting aromatic compounds of the formula...
37	5756510	Benzamide analogs useful as PARP (ADP-ribosyltransferase, ADPRT) DNA repair enzyme inhibitors A range of 3-oxybenzamide compounds and related quinazolinone compounds are disclosed which can act as potent inhibitors of the DNA repair enzyme poly(ADP-ribose) polymerase or PARP enzyme (EC...
38	5710331	Preparation of N-alkenyl carboxamides Preparation of N-alkenyl carboxamides of the general formula I ##STR1## in which the radicals R 1 to R 4 independently stand for hydrogen or for aliphatic, cycloaliphatic, or aromatic radicals,...
39	5691376	Substituted biphenyl derivatives A compound of the following structure: ##STR1## wherein R 8 =H: R 1 =alkyl, cycloalkyl, arylalkyl, aryl; R 2 =cycloalkyl, aryl, C 3 -C 10 alkyl; X,Y=O, S(O) n , NH; Z=CO 2 R 3 ,...
40	5672751	Method for producing alkylsulfinylbenzamides and 1,2-benzisothiazol-3-ones A method for producing an alkylthiobenzamide by carrying out a reaction of a halobenzamide with an alkanethiol in the presence of a base in a heterogeneous solvent; a method for producing an...
41	5654478	Preparation of N-alkenylcarboxamides N-Alkenylcarboxamides of the formula I ##STR1## where at least one of the radicals R 1 is hydrogen, the second radical R 1 is hydrogen or C 1 -C 4 -alkyl and R 2 is hydrogen or an aliphatic,...
42	5646329	Cyclopropylamine derivatives 2-fluoro-cyclopropylamine is prepared in an advantageous manner by reacting an N-vinyl compound with a carbene of type FXC: (where X=chlorine or bromine) to give the corresponding cyclopropylamine...
43	5614647	Intermediates for the synthesis of bisindolylmaleimides The present invention provides a novel synthesis of the compounds of Formula (I): ##STR1## The compounds are produced in high yield and without utilizing expensive chromatographic separations. The...
44	5609848	Radiohalogenated small molecules for protein labeling Haloaryl compounds are lithiated and thereafter metalated with one of the following organometallic groups: Sn(n--Bu) 3 or SnMe 3 . The resulting aryltin compound can be transmetalated in...
45	5587513	Polyether-substituted imide compounds and their use The present invention relates to novel polyether-substituted compounds of imides and their use as surface-active agents.
46	5580893	Nitroxyalkylamide derivatives Nitroxyalkylamide compounds having the formula: R 1 --(A) n --CONH--B'--ONO 2 wherein R 1 is an optionally substituted furyl, furyloxy, thienyl, thienyloxy, isoxazolyl, phenoxy, phenylthio or...
47	5532363	Heteroaryl substituted oxazinone compounds for the preparation of taxol Process for the preparation of a taxol intermediate comprising contacting an alcohol with an oxazinone having the formula: ##STR1## wherein R 1 is aryl, heteroaryl, alkyl, alkenyl, alkynyl or OR 7...
48	5473095	Process for the preparation of chlorinated 4,5-difluorobenzoic acids, -benzoic acid derivatives and -benzaldehydes The present invention relates to a process for the preparation of compounds of the formula ##STR1## in which R 1 is --CN, --COOH, --COOR', R' being an organic radical having 1 to 6 carbon atoms,...
49	5430060	Acetamide derivatives The invention concerns novel N-phenylacetyl and related acyl derivatives of (4-amino-2,6-dimethylphenylsulphonyl)nitromethane and pharmaceutically acceptable salts thereof which are inhibitors of...
50	5393776	Tocotrienol analogs in the treatment of hypercholesterolemia and hyperlipidemia This invention relates to structurally novel acyclic tocotrienol analogs, which are useful for cholesterol/lipid lowering in cases of hypercholesterolemia and hyperlipidemia, and for...

Matches 1 - 50 out of 216

1 2 3 4 5 >