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7589235 |
High yield and rapid synthesis methods for producing metallo-organic salts
A new method for preparing salts of metal cations and organic acids, especially divalent salts of alkaline earth metal ions from group II of the periodic system and carboxylic acids. The method...
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7358384 |
Processes for the recovery of optically active diacyltartaric acids
When a salt of an amine and an optically active diacyltartaric acid, or a diastereomer salt of an optically active amine and an optically active diacyltartaric acid, obtained by optically resolving...
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7311837 |
Process for the continuous recovery of free tartaric acid from raw materials containing potassium hydrogentartrate
In a process for the continuous recovery of free tartaric acid from raw materials containing potassium hydrogentartrate, the same are mixed with water and the potassium hydrogentartrate is...
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7052875 |
Stable gene preparations
The invention is directed to the retention of the stability of formulations useful for a gene therapy during the preparation and preservation. In the invention, at least one saccharide and/or at...
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6995286 |
Process for preparing isomers of salbutamol
A process for making optically pure (R) and (S) salbutamol comprises obtaining the (R) or (S) isomer of either salbutamol or a salbutamol precursor in substantially optically pure form by resolving...
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6670505 |
Process for the recovery of organic acids from aqueous solutions
A process for recovering a desired organic acid from a solution includes the steps of: providing an aqueous solution including at least one desired organic acid or its acid anion; adjusting the...
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6652820 |
Methods of making cesium salts and other alkali metal salts
A method of making a cesium salt is described and involves reacting a cesium sulfate containing solution with lime to form 1) a solution containing at least cesium hydroxide and 2) a residue...
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6534678 |
Process for producing tartaric acid from a raw material containing potassium hydrogentartrate
Process for producing tartaric acid from a raw material whose dry matter comprises at least 5 wt% potassium hydrogentartrate wherein the raw material containing potassium hydrogen tartrate (KHT) is...
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6495711 |
Process for preparing (-)-(1S, 4R) N-protected 4-amino-2-cyclopentene-1-carboxylate esters
The invention relates to a process for preparing (−)-(1S,4R) N protected 4-amino-2-cylcopentene-1-carboxylate esters represented by the formula (I) wherein R 1 and R 2 are as described...
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6376223 |
Process for purifying polycarboxylic acids
Polycarboxylic acids are purified by contacting a crude polycarboxylic acid with a solvent to produce a substantially pure polycarboxylic acid. The solvent is chosen so that the impurities are...
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6346649 |
Process for the recovery and recycle of D-tartaric acid
There is provided a process for the recovery of essentially enantiomerically pure D-tartaric acid from aqueous and organic waste streams generated in the resolution of racemic...
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6320069 |
Production of optically active ketone
Process for producing an optically active ester by reaction of a racemic alcohol with an optically active amino or tartaric acid derivative, a process for producing an optically active alcohol by...
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5763656 |
Method of preparing tartaric acid
A method of preparing tartaric acid in which 5-ketogluconate is oxidized in a carbonate buffer at an alkaline pH preferably in the range of 8 to 10 using vanadate.
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5762951 |
Effervescent composition and tablet made there from
The present invention relates to an acidic effervescent component for direct tableting of effervescent tablets and a process for its preparation.
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5576459 |
Quaternary nitrogen or phosphorus chirates
An optically-active or chiral compound is described which comprises (A) at least one quaternary nitrogen or phosphorus cation provided that if the cation is a quaternary nitrogen cation containing...
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5451687 |
Process for producing O,O'-diacyltartaric anhydride and process for producing O,O'-diacyltartaric acid
An industrial process for producing O,O'-diacyltartaric anhydride with high purity and high efficiency is disclosed. According to the process of the invention, a carboxylic acid of the formula (I):...
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5412126 |
Carboxylic acid sorption regeneration process
Carboxylic acids are sorbed from aqueous feedstocks into an organic liquid phase or onto a solid adsorbent. The acids are freed from the sorbent phase by treating it with aqueous alkylamine thus...
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5349084 |
Process for recovering high-purity organic acid
The present invention relates to a process for inexpensively and effectively recovering a high-purity organic acid, according to which a crude organic acid is subjected to extraction treatment with...
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5278256 |
Rapidly degradable poly (hydroxyacid) compositions
The depolymerization of poly(hydroxyacids) in a liquid medium is enhanced by the presence of a quaternary ammonium compound. Poly(hydroxyacid) polymers containing a quaternary ammonium salt are...
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5245078 |
Process for separating an organic acid or acids from an organic acid-containing solution
A process for separating an organic acid or acids from an organic acid-containing solution obtained by a fermentation method in which glucose is used as starting material, which comprises...
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5135947 |
1-phenyl-3-naphthalenyloxypropanamines and their use as selective serotonin reuptake inhibitors
The present invention provides 1-phenyl-3-naphthalenyloxypropanamines which are selective inhibitors of serotonin uptake.
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5087746 |
Process for the production of high purity tartaric acid
Disodium tartrate which can be easily converted to tartaric acid is produced by hydrolysis of an epoxysuccinate. Formation of impurities is minimized and the reaction time shortened by performing...
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5017723 |
Substituted ethylamines, their preparation process, their use as medicine and their synthesising agents
Substituted ethylamines of the formula ##STR1## wherein R 1 is phenyl optionally mono-, di- or trisubstituted by halogen, lower alkyl, lower haloalkyl or lower alkoxy, or is an aromatic...
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5001245 |
Process for producing metallic salt of ethercarboxylic acid
A preparation of metallic salt of ethercarboxylic acid in a pure form by restraining the formation of fumaric acid likely to occur when maleic acid and/or maleic anhydride react with oxycarboxylic...
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4950783 |
Treatment of hypertension
Compositions containing (-)-5-{(R)-1-Hydroxy-2[(R)-1-methyl-3-phenylpropyl)amino]eth
yl}salicylamid e exhibit potent vasodilating β-adrenergic blocking properties and are useful for the treatment...
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4923983 |
Method of resolving cis 3-amino-4-[2-(2-furyl)eth-1-yl]-1-methoxycarbonylmethyl-azetidin-2-one
Cis αα/ββ-3-amino-[2-(2-furyl)eth-1-yl]-1-methoxycarbony lmethyl-azetidin-2-one is resolved via optically active tartaric acid.
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4732709 |
Preparation of optically-active di-(3-chloro-2-oxy-propyltrimethylammonium)-tartrate
Process for the production of optically-active di-[3-chloro-2-oxy-propyltrimethylammonium]-tartrate. Racemic 3-chloro-2-oxy-propyltrimethylammonium-chloride is converted by racemate resolution with...
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4705894 |
Process for recovery of organic acids from aqueous solutions
A mixture of trialkyl phosphine oxides (HTRPO) was prepared having the formula: ##STR1## wherein R 1 , R 2 and R 3 are same or different alkyl groups of 5 to 9 carbon atoms and the total number...
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4704407 |
Soluble dobutamine salts
Hydroxyalkanoic or alkandioic acid salts of dobutamine having desirable water solubility, useful in preparing intravenous solution for treatment of cardiogenic shock.
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4656303 |
Novel resolution method of racemic mixture
A novel resolution method of a racemic mixture, wherein four kinds of salts are dissolved in a resolving solvent to fractionally crystallize a desired optically active isomer through an exchange...
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4652584 |
Acetylenic phenoxypropanol derivatives and pharmaceutical compositions for the treatment of hypertension
Phenoxypropanol derivatives having a 2-acetylenic moiety on the phenyl group thereof of the following formula (I): ##STR1## and their use as anti-hypertensives, e.g. in man. Also part of the...
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4597902 |
N-(arylthioalkyl)-N'-(aminoalkyl)ureas
N-(arylthioalkyl)-N'-(aminoalkyl)ureas and thioureas and oxidation derivatives having the formula ##STR1## wherein B is thio, sulfinyl or sulfonyl; R 1 and R 2 are hydrogen, loweralkyl,...
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4411913 |
8'-[(3-Amino-2-hydroxy-propoxy)]-spiro-[cyclopentane-1,2'(1 'H)-(3'H)naphtalen]-4'(3'H)-ones
Compounds of formula I ##STR1## wherein (i) m is O, n is 2 and p is 1 or (ii) m is 0 or 1, n is 1, and p is 1 or (iii) m is 1, n is 1 or 2 and p is 0, R 1 is (i) alkyl of 3 to 7 carbon...
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4399077 |
Certain polyoxy perfluorinated surface active oligomers
Perfluorinated surface-active block or random oligomers of the formula ##STR1## where R denotes a C 2 -C 18 -hydrocarbon or- hydrofluorocarbon radical, Y denotes a C 6 -C 13 -fluorocarbon...
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RE31139 |
Manufacture of malic acid
Synthesis of malic acid from maleic and/or fumaric acid in a reaction zone whose surfaces exposed to the reaction mixture consist of titanium, zirconium or tantalum and alloys containing at least...
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4322437 |
Spiro substituted indanones and tetralones
The present invention relates to a compound of formula I, ##STR1## wherein A is straight chain alkylene of 2 to 4 carbon atoms, or straight chain alkenylene of 2 to 4 carbon atoms, n is 1, 2 or...
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4322370 |
Polycyclic compounds
Compounds of the formula (II): ##STR1## and pharmaceutically acceptable salts thereof, wherein R 1 is phenyl or naphthyl or substituted phenyl or naphthyl group; R 2 is: ##STR2## wherein R 5 is...
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4319045 |
Process for production of a tartronic acid solution
The invention disclosed herein describes a process of making a solution of tartronic acid. The tartronic acid solution was produced by a controlled oxidation reaction employing potassium...
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4150241 |
Process for the production of pure racemic acid and mesotartaric acid and separation of maleic acid from synthetic tartaric acid
Pure racemic acid (dl-tartaric acid) and meso tartaric acid are produced by reaction of an alkali maleate with aqueous hydrogen peroxide in the presence of an alkali tungstate in a process wherein...
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4146637 |
Anti-inflammatory N-acyl substituted benzamides
There are disclosed N-acyl substituted benzamides of the general formula: ##STR1## wherein: X is carbon or nitrogen; R 1 is hydrogen, alkyl, halogen, trifluoromethyl, alkoxy, phenoxy or...
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4138427 |
Sequenced surfactant oligomers of the polyhydroxylated polyether type, process for preparing them and composition containing them
Polyhydroxylated sequenced oligomer surfactants of the formula: HO--C 2 H 3 (CH 2 OH)O-- n --C 2 H 3 (CH 2 ZR)O-- m --C 2 H 3 (CH 2 OH)O-- n , H where R is C 14 -C 18 alkyl, Z...
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4110472 |
Derivatives of 1-(disubstituted phenoxy)-3-amino-2-hydroxypropanes
N-Diphenylmethyl and o-biphenylenemethyl derivatives of 1-(disubstituted phenoxy)-3-amino-2-hydroxypropane and their salts are useful for combatting cerebrovascular insufficiency and producing...
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4105795 |
Antispasmodic substituted sulphoximides
This invention provides compounds of the general formula I ##STR1## wherein R 1 and R 2 independently represent groups selected from the group consisting of straight chain alkyl groups; branched...
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4085138 |
Process for optical resolution of crude trans-1,2-cyclohexanediamine
Crude trans-1,2-cyclohexanediamine (DACH) contained in a mixture of amines derived as a by-product from the manufacture of 1,6-hexanediamine (HDA) or any other synthesis process crude by-product...
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4082851 |
Sulphonamides, compositions containing the same and methods for using the same in the treatment of hypertension or odemeas
The invention relates to a series of new compounds, salts thereof and to methods for the preparation of the compounds which have the general formula ##STR1## in which R 1 stands for an...
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RE29588 |
Preparation of d-2-amino-1-butanol salts
A racemic mixture of dl-2-amino-1-butanol is resolved with separation of the d-2-amino-1-butanol by crystallizing as a salt with L(+)-tartaric acid from an essentially anhydrous solution in ethanol...
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4060535 |
Process for the production of metal salts of organic acids
Metal salts of organic acids are produced rapidly and efficiently by subjecting a reaction mixture that contains a metal oxide, hydroxide, or carbonate, an organic acid that has a melting point...
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4041075 |
Phenoxy-alkanolamine derivatives
Novel 1-amidoaryloxy-3-amidoalkylamino-2-propanol derivatives, processes for their manufacture, pharmaceutical compositions containing them and methods of using them in the treatment of heart...
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4041074 |
1-Hydroxyaryl-2-amidoalkylaminoethanol derivatives
Novel 1-hydroxyaryl-2-amidoalkylaminoethanol derivatives, processes for their manufacture, pharmaceutical compositions containing them and methods of using them in the treatment of heart failure...
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4028407 |
Method of producing tartaric acid
Tartaric acid is produced by epoxidizing acid calcium maleate with aqueous hydrogen peroxide in the presence of a tungstic acid-containing catalyst to produce sparingly soluble acid calcium...
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