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7589235 High yield and rapid synthesis methods for producing metallo-organic salts  
A new method for preparing salts of metal cations and organic acids, especially divalent salts of alkaline earth metal ions from group II of the periodic system and carboxylic acids. The method...
7205273 Fusogenic liposomes  
The present invention relates to liposomes and virosomes and, more particularly, to liposomal and virosomal delivery systems for transporting materials such as drugs, nucleic acids and proteins.
7157449 Medicament for the treatment of diseases caused by parasitic protozoa  
The present invention relates to the use of an inhibitor of CTP synthetase, such as a glutamine analogue, and a substance capable of suppressing toxic effects thereof in vivo, in the manufacture of...
7129375 Metal complexes of α amino dicarboxylic acids  
Neutral alpha amino diacid complexes of trace minerals and their use for animal nutrition.
7101855 Pyroglutamic acid derivatives and related compounds which inhibit leukocyte adhesion mediated by VLA-4  
Disclosed are pyroglutamic acid derivatives and related compounds which bind VLA-4. Certain of these compounds also inhibit leukocyte adhesion and, in particular, leukocyte adhesion mediated by...
6977311 Process for synthesizing L-γ-methylene glutamic acid and analogs  
A process for synthesizing substantially enantiomerically pure L-amino acids, particularly L-γ-methylene glutamic acid, and esters and salts thereof. The process includes the derivatization of...
6911431 Pharmaceutical angiostatic dipeptide compositions and methods of use thereof  
Disclosed are methods of inhibiting neovascularization in a subject by administering to the subject a pharmaceutical preparation of R′-Glu-Trp-R″.
6881861 Method of purifying glutamic acid by transition recrystallization  
Disclosed herein is a method of purifying L-glutamic acid by transformation recrystallization which method comprises maintaining crude crystals of L-glutamic acid containing α crystals of...
6777396 Feed for livestock  
A composition for livestock feed, comprising a feed for livestock and at least two additives selected from the group consisting of nucleic acid, glutamine and glutamic acid; and a method for...
6696611 Chemical methods  
The present invention provides a method for enantioselectively reducing a prochiral carbon centered radical having one or more electron donator groups attached directly to the central prochiral...
6673942 Resolution of DL-racemic mixtures  
The present invention relates to a process for the resolution of DL-racemic mixtures of compounds which crystalize in the form of a conglumerate. Both, the D and L-enantiomers are obtained...
6627732 Glutathione derivatives and their dosage forms  
The present invention provides a glutathione derivative having a dramatically enhanced hematopoiesis promoting effect in the living body represented by the formula (I): where A represents H or a...
6600069 Benzene tricarboxylic acid derivatives as insulin receptor activators  
Compounds of Formula I, and pharmaceutical compositions containing these compounds, activate the insulin receptor kinase, which leads to an increased sensitivity to insulin and an increase in...
6599940 Synthesis of 2-hydroxymethylglutamic acid and congeners thereof  
One aspect of the present invention relates to 2-hydroxymethylglutamic acid and congeners thereof. A second aspect of the invention relates to a method of synthesizing 2-hydroxymethylglutamic acid...
6414029 Vanadium complexes of monohydroxamates and pharmaceutical compositions comprising them  
Monohydroxamate vanadium complexes of the formula (1): R—CO—NHOH.X, wherein R is a residue selected from: (i) H 2 N—CH(COY)—(CH 2 ) n —, wherein n is 1, 2 or 3, and Y is OH or NH 2 ; (ii)...
6392094 Method for recovering amino acids  
A method for recovering amino acids, which comprises supplying a mixed solution containing inorganic acid salts, amino acids and non-electrolytes such as saccharides to a first-step resin layer...
6201132 Inhibitors of DP-mediated processes, compositions, and therapeutic methods thereof  
Compounds selected from those of general formula ##STR1## and A is selected from specified aminoacyl compounds are inhibitors of DP-IV mediated processes.
6147259 Process for producing glutamic acid  
An indirect acidulation process for producing glutamic acid from an aqueous feed containing a glutamate resulting from fermentation includes: a) contacting an aqueous feed stream at an elevated...
6051734 Process for the optical resolution of 3-(p-chlorophenyl)-glutaramide  
A process for the optical resolution of racemic 3-(p-chlorophenyl)glutaramide (GAM) into its R isomer R--COOH and its S isomer S--COOH, which process includes the steps of either: (1) reacting...
5998594 Self-assembling, chromogenic receptors for the recognition of medically important substrates and their method of use  
A chromogenic receptor comprises a self-assembled chromogenic compound having at least one intrinsic binding site. The chromogenic compound is characterized by the property of producing a...
5994560 Resolution of racemic mixtures using polymers containing chiral units  
Described herein is a novel process to resolve a racemic compound into its optically active isomers without need for chemical transformation such as salt formation. The process advantageously...
5990165 Pharmaceutical compounds  
A pharmaceutical compound of the formula: ##STR1## in which n is 1 or 2, R 1 is --CO 2 H, R 2 is hydrogen or C 1 -4 alkyl and R 3 is hydrogen, C 1 -10 alkyl, C 2 -10 alkenyl, optionally...
5981564 Water-soluble derivatives of paclitaxel, method for producing same and uses thereof  
The invention relates to new paclitaxel derivatives showing an increased solubility in water. More particularly, the invention relates to glutarylpaclitaxel, glutarylpaclitaxel 6-aminohexanol...
5907059 Process for the preparation of monosodium glutamate  
The invention provides a process for the preparation of monosodium glutamate from a fermentatively prepared solution containing monoammonium glutamate, the process comprising: a) contacting the...
5837872 Process for preparation of N-acyl-aminodiacids  
This invention relates to an improved process for preparing selected N-acyl-aminodiacids such as lauroyl glutamic acid.
5559092 Cosmetic composition  
A composition suitable for topical application to mammalian skin and hair for inducing, maintaining or increasing hair growth comprises a hair growth promoter chosen from glutamine derivatives and...
5536815 Cyclopropyl based O- and N- and S-protecting groups  
The present invention is directed to the use of a cyclopropylmethyl derivative as a protecting group for compounds containing an amino group, carboxy group, amido group, mercapto group or hydroxy...
5428063 Use of betaine as a hepatic generator of S-adenosylmethionine and as a protective agent against hepatotoxicity  
This invention encompasses pharmaceutical compositions in the dietary supplement for treating or preventing fatty infiltration, the first stage of cirrhosis of the liver comprising and...
5279744 Method for purification of an amino acid using ion exchange resin  
A method for purification of an amino acid which comprises contacting an amino acid solution containing impurities with an ion exchange resin to selectively adsorb the amino acid onto the resin,...
5187270 Racemization free attachment of amino acids to a solid phase  
This invention pertains to amino acids attached to a solid support in a racemization free manner and to a method of covalently linking amino acids to solid supports for use in solid phase peptide...
5091559 Process for the preparation of alkyl 4-oxobutyrate and its acetals  
A process is disclosed for forming alkyl 4-oxobutyrates and its acetals which comprises reacting under anhydrous conditions acrolein or its acetals with carbon monoxide and an alcohol of the...
4942248 Tertiary-alkyl esters of 1H-benzotriazole-1-carboxylic acids  
Tertiary-butyl and tertiary-amyl esters of 1H-benzotriazole-1-carboxylic acids are useful blocking agents for blocking the amino or imino groups of amino acids. The six-membered ring of the...
4929755 Process for making an optically active mixture of an N-acyl-amino acid or ester containing at least two chiral centers  
In the process of hydrocarboxylating an α-enamide with CO and H 2 O or an organic hydroxyl compound to produce an N-acyl-α-amino acid or ester, respectively, the improvement comprising using as...
4912228 Process of extraction of amino acids from aqueous solutions thereof  
An improvement in the process of extraction of amino acids from aqueous solutions in which the amino acids are extracted with quaternary ammonium extractants. A pretreatment of the amino acid...
4720573 Process for synthesis of glutamic acid from acrylate, amide and synthesis gas  
A process for the synthesis of glutamic acid intermediate from an acrylate, amide and syngas by reacting them in the presence of a catalyst comprising a cobalt-containing compound, a bis-phosphine...
4675196 Process for the total or partial elimination of aspartic acid and glutamic acid from protein hydrolyzates and mixtures of aminoacids, and aminoacid compositions therefrom  
A process for the total or partial elimination of aspartic acid and glutamic acid from a protein hydrolyzate or a mixture of aminoacids is described, which consists of passing the hydrolyzate or...
4661606 Extraction of amino acids from aqueous mixtures and quaternary ammonium salt intermediates produced therein  
Amino acids can be purified and/or concentrated by extracting aqueous mixtures such as fermentation broths by contacting an aqueous mixture containing amino acids with an organic solution...
4602096 Process for the racemization of N-acetyl-D,L-α-aminocarboxylic acids  
N-acetyl-D(L)-α-aminocarboxylic acids are thermally racemized by melting, adding a small amount of acetic anhydride to the melt and heating to a temperature between the melting temperature and...
4540792 Process for the preparation of a free L α-amino acid  
This invention relates to a process for the preparation of free L α-amino acids by the complete conversion of their D antipodes taken individually or possibly in racemic mixtures. The process...
4459423 Process for producing α-amino acids  
A process for producing efficiently and economically without using strong acids nor strong bases, α-amino acids from α-amino acid amides by hydrolyzing α-amino acid amides in an aqueous medium...
4436910 Process for the production of aqueous solutions of sodium salts of α- a  
Aqueous solutions of sodium salts of α-aminocarboxylic acids practically free of foreign salts are produced by saponifying the corresponding hydantoin at a temperature between 110° C. and 180°...
4243814 Process for the chemical catalytic hydrolysis of an α-aminonitrile or of one of the salts thereof  
A process for the chemical catalytic hydrolysis of an α-aminonitrile or of one of the salts thereof, characterized in that an aqueous solution containing at least one carbonyl derivative is...
4220590 Asymmetric catalysis  
New optically active bis phosphine compounds which are usful in optically active catalysts. Such catalysts are particularly useful in catalytic asymmetric hydrogenation.
4073898 Composition for reducing the oily appearance of the hair and skin  
A composition for treating oily hair or skin to reduce the oily appearance thereof comprises in an appropriate vehicle an active compound having the formula ##STR1## wherein R 3 is lower alkyl...
3991107 Haloamine transfer  
N-haloamines also containing a hydroxy group, a sulfonic acid group, an N-acyl group or a carboxylic acid group are prepared by reacting an amine with a different N-haloamine to form the...
3985722 Process for preparing N-higher aliphatic acyl derivatives of amino acids, peptides or proteins  
A mixed acid anhydride consisting of higher fatty acid having 6 to 22 carbon atoms and sulfuric anhydride is reacted with amino acids, peptides or proteins in the presence of a base to form...
3873621 Method for preparing amines  
This invention relates to the reduction of compounds containing an imminium group to an amine with an alkali metal cyanoborohydride or quaternary ammonium cyanoborohydride or the corresponding...
3869474 3,4-DIHYDROXY-BENZYLALCOHOL AMINO DERIVATIVES  
A 3,4-dibenzyloxyphenyl-glyoxal is condensed with 3,4,5-trimethoxyphenethylamine compound of the formula: ##SPC1## Wherein R is hydrogen or methyl. The resultant intermediate product is subjected...
3855249 4-PHENOXY-3-HYDROXY-BUTYRAMIDINE DERIVATIVES  
The compounds of the formula: ##SPC1## In which R is hydrogen atom or C 1 -C 5 alkyl and X is hydrogen or OH and their acid addition salts are useful in therapy, e.g., as anti-arrhythmia agents.
3818076 BISDIGUANIDE SALTS  
Novel crystalline, non-hygroscopic salts of chlorhexidine having substantial water solubility and the ability to dissolve rapidly even in very cold water to give a solution of chlorhexidine...
Matches 1 - 50 out of 109 1 2 3 >