Patents in Class 562/495

Matches 1 - 50 out of 152

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Match	Document	Document Title
1	RE43006	Aryl-acrylic acid esters The acrylic acid esters of Formula I are useful for the delivery of organoleptic compounds, especially for flavors, fragrances, masking agents and antimicrobial compounds. They can also deliver...
2	8026280	Histone deacetylase inhibitors Histone deacetylase is a metallo-enzyme with zinc at the active site. Compounds having a zinc-binding moiety, such as, for example, a carboxylic acid group, can inhibit histone deacetylase. Histone...
3	6936636	5-[phenyl-tetrahydronaphthalene-2-yl dihydronaphthalen-2-yl and heteroaryl-cyclopropyl]-pentadienoic acid derivatives having serum glucose reducing activity Compounds of the formula: where the variables have the meaning defined in the specification are capable of reducing serum glucose levels in diabetic mammals without the undesirable side effects of...
4	6927302	Process for the arylation of olefins The present invention encompasses a process for preparing arylolefins by reacting one or more arylamines with one or more organic nitrites, in the presence of one or more olefins which bear at...
5	6756508	Cinnamic acid salts, processes for their preparation, and their use as medicaments The present invention relates to new cinnamic acid salts of salmeterol, processes for the preparation thereof as well as the use thereof as pharmaceutical compositions.
6	6602859	Photocurable hyaluronic acid derivative and process for producing the same, and photocured crosslinked-hyaluronic acid derivative and medical material using the same A photocurable hyaluronic acid derivative of the present invention comprises hyaluronic acid and a photoreactive crosslinking group bonded thereto, wherein a 1.0 wt. % aqueous solution of the...
7	6599938	Compounds having MIF antagonist activity There is disclosed a genus of optionally substituted Schiff base condensation products (and the carba analogs thereof) comprising an amino acid component and a benzaldehyde component, that have MIF...
8	6538154	Process for the preparation of cinnamic esters The present invention relates to a process for the synthesis of cinnamic esters and/or cinnamic acids by condensation of aldehydes with carboxylic anhydrides, using iron(II) salts as catalyst.
9	RE37947	Aromatic polyenic compounds and pharmaceutical/cosmetic compositions comprised thereof Novel pharmaceutically/cosmetically-active aromatic polyenic compounds have the structural formula (I): and are useful for the treatment of a wide variety of disease states, whether human or...
10	RE37670	Antiproliferative and neurotrophic molecules Neurotrophic and antiproliferative compounds related to the antiepileptic drug valproate are provided. These compounds are useful for promoting neuronal function as in neurodegenerative disorders...
11	6331655	Process for the preparation of aromatic carbonyl compounds from styrenes The present invention relates to a novel process for the preparation of aromatic carbonyl compounds by oxidative cleavage of styrenes using lipases and hydrogen peroxide or hydrogen peroxide donors...
12	6278019	Process for acyloxylating side chains of alkyl-substituted aromatic compounds and catalysts used therefor The present invention is a method for acyloxylating an alkyl group substituted aromatic compound at the side chain, by letting the alkyl group substituted aromatic compound and a carboxylic acid...
13	6162943	Method for producing α-alkoxy-α-trifluoromethyl-aryl acetic esters and -aryl acetic acids Process for the preparation of α-alkoxy-α-trifluoromethyl-arylacetic esters of the formula (I) ##STR1## wherein R is a component selected from the group consisting of C1 -C6 -alkyl, C2 -C6 -...
14	6096918	Aryl-acrylic acid esters The acrylic acid esters of Formula I are useful for the delivery of organoleptic compounds, especially for flavors, fragrances, masking agents and antimicrobial compounds. They can also deliver...
15	6087519	Rubber-to-metal adhesion promoter, metal reinforcement, composition made of rubber, metal reinforcement and rubber-to-metal adhesion promoter, and use of the rubber-to-metal adhesion promoter The invention relates to an adhesive substance for improved adhesion between a vulcanizable polymer and a metallic reinforcing carrier.The use of an adhesive substance with the following structure...
16	6028110	Succinyl hydroxamic acid, N-formyl-N-hydroxy amino carboxylic acid and succinic acid amide derivatives as metalloprotease inhibitors A pharmaceutical or veterinary composition comprising a compound of formula I ##STR1## wherein X is a --CO2 H group and R1, R2, R3, R4, R5 are as defined in the specification, or a salt, hydrate or...
17	5981620	Dental compounds, compositions, products and methods The invention provides polymerizable dental, compounds, compositions, including the compounds and products for mixing the compositions and methods of using the compositions. Aryl acid compounds are...
18	5972839	2-fluoroacrylic acid derivatives, novel mixtures of herbicides and antidotes, and their use The invention relates to novel α-fluoroacrylic acid derivatives, to active compound/antidote combinations which comprise α-fluoroacrylic acid derivatives and are outstandingly suitable for use in c...
19	5910606	Process for making α,β-unsaturated carboxylic acids α, β-Unsaturated acids of the formula ##STR1## wherein R1 signifies C1 -C5 -alkyl and Ar signifies an aryl group which is optionally substituted by one or more substituents selected from the g...
20	5817862	Process for the preparation of cinnamic acid derivatives The invention relates to a process for the preparation of cinnamic acid derivatives which involves reacting chlorinated aromatic compounds and acrylic acid derivatives in the presence of palladium...
21	5808148	Preparation of α,β-unsaturated carboxylic acids and esters Disclosed is a process for the preparation of α,β-unsaturated carboxylic acids and esters thereof which comprises contacting formaldehyde or a source of formaldehyde with a carboxylic acid, ester o...
22	5639894	Carbonylation of allylic alcohols and synthesis of an ambergris fragrance compound A process for the carbonylation of allylic alcohols such as nerolidol, farnesol, or their monocyclic analogues with carbon monoxide at a pressure of at least 30 bar in the presence of a polar...
23	5516932	Halogenated cinnamic acids and esters thereof, processes for the preparation thereof and halogenated aryldiazonium salts The present invention relates to compounds of the formula ##STR1## in which R1 and R2 are identical or different and are hydrogen or an alkyl radical having 1 to 18 carbon atoms and optionally...
24	5436369	Alicyclic phospholipase A2 inhibitors Certain novel alicyclic compounds are effective phospholipase A2 (PLA2) inhibitors.
25	5414108	Process for the preparation of carboxylic acids and derivatives of them The subject matter of the invention is a process for the preparation of carboxylic acids and derivatives of them of the general formula ##STR1## wherein R means hydrogen, or a C1-4 alkyl or a (C1-5...
26	5391819	Process of making chiral 2-aryl-1,4-butanediamine derivatives as useful neurokinin-A antagonists Disclosed herein is a process of making chiral 2-aryl-1,4-butanediamine derivatives useful as neurokinin-A antagonists of Formula 7 ##STR1##
27	5360924	Process for preparing aromatic olefins Process for preparing aromatic olefins of the formula (1) ##STR1## in which R1 -R3 are hydrogen, alkyl (C1 -C8) , alkoxy-(C1 -C5), phenyl, fluorine, chlorine, bromine, --OH, --NO2, --CN, --CHO,...
28	5359122	Preparation of 3-arylacrylic acids and their derivatives The preparation of 3-arylacrylic acids and their derivatives I ##STR1## where Ar is aryl which can additionally have substituents which do not react with ketene and are stable under the conditions...
29	5344843	Cat-1 inhibitors, pharmaceutical compositions and methods of use The invention relates to compounds of the formula ##STR1## wherein R1, R2, R2 ' X, Y, Z, A, B, Q and n are as described herein. Their pharmaceutically acceptable salts, and when appropriate,...
30	5334750	Process for the preparation of cinnamic acid derivatives Cinnamic acid derivatives, in particular 2-ethylhexyl p-methoxycinnamate and 2-isoamyl p-methoxycinnamate, are prepared avoiding particular effort for workplace hygiene and ecology by using...
31	5276217	Cyclic anti-tumor promoter compounds, compositions and methods for production and use Novel cyclic anti-tumor promoter compounds and therapeutic compositions are disclosed, along with method for their production and use as anti-cancer and cancer-prevention agents.
32	5274171	Process for the palladium catalyzed coupling of a diazonium salt with an olefinic bond A "one-pot" process for the palladium catalyzed coupling of a diazonium salt with an olefinic bond, in the aqueous medium in which the diazonium salt is made, by employing a carboxylic acid as a...
33	5268506	Process for producing α, β-unsaturated carboxylic acid An α, β-unsaturated carboxylic acid is produced by catalytically reacting an α-hydroxycarboxylic acid amide of the formula (1), ##STR1## where R1 and R2 are independently selected from the group co...
34	5206430	Method for obtaining high-purity cinnamic acid There is here disclosed a method for obtaining high-purity cinnamic acid containing less metals from crude cinnamic acid containing a metallic catalyst which is a mixture prepared by the synthetic...
35	5017723	Substituted ethylamines, their preparation process, their use as medicine and their synthesising agents Substituted ethylamines of the formula ##STR1## wherein R1 is phenyl optionally mono-, di- or trisubstituted by halogen, lower alkyl, lower haloalkyl or lower alkoxy, or is an aromatic heterocycle...
36	4990662	Process for preparation of alpha, beta-unsaturated acids Catalyst and process are disclosed for the improved preparation of alpha, beta-unsaturated acids. The catalyst comprises a porous silica gel component and a Group IA alkali metal component, which...
37	4933367	Carboxylic acid derivatives, processes for the preparation thereof, the use thereof, and pharmaceutical compositions which contain these compounds This invention relates to carboxylic acid derivatives and their use thereof. The compounds are useful in treatment of various diseases such as diabetes, prediabetic conditions, adipositas ailments...
38	4898883	1-Substituted derivatives of 4-methoxy-2,3,6-trimethylbenzene, process for their preparation and medicinal and cosmetic compositions containing them The present invention relates to 1-substituted derivatives of 4-methoxy-2,3,6-trimethylbenzene which are useful in cosmetic or pharmaceutical preparations for use in the treamtnet of dermatological...
39	4892940	Aromatic naphthyl compounds, a process for their preparation and their use in human and veterinary medicine and in cosmetic compositions An aromatic naphthyl compound of the formula ##STR1## wherein n is 0 or 1, R' is hydrogen, OH, acyloxy, alkoxy or NH2, R" is hydrogen or lower alkoxy, or R' and R" taken together form an oxo,...
40	4857658	Preparation of (Z)-2-(2-arylethenyl)arylcarboxylic acids (Z)-2-(2-arylethenyl)arylcarboxylic acids of the general formula I ##STR1## where A is a group for completing an aromatic ring system and Ar is an aromatic radical, are prepared by reacting a...
41	4822913	Process for preparing carboxylic acids from esters of carboxylic acids Esters of carboxylic acids of the formula RCH2 COOR"' and R'CH:C(R")COOR"' are reacted to form a carboxylic acid and an aliphatic alcohol R"'OH wherein R, R', and R" are individually selected from...
42	4806683	Preparation process of cinnamic acids A process is disclosed which prepares a cinnamic acid from a cinnamate ester by starting the hydrolysis reaction of the cinnamate ester with an alkali by use of water as a solvent in a...
43	4748273	Amphiphilic diacetylene compound containing benzene ring and film prepared therefrom Amphiphilic diacetylene compound having benzene ring. The compound can readily form a single crystal and is photopolymerizable. A stable monomolecular film or built-up film can be prepared from the...
44	4727181	Process for the preparation of α-halocinnamate esters Prepare esters of α-halocinnamic acid and related compounds in high yield under relatively mild conditions.
45	4723028	Stilbene derivatives The application discloses certain stilbene compounds, pharmaceutical compositions thereof, method of treating thereof, method of diagnosis therewith, and method for the preparation thereof. The...
46	4713486	Novel compounds A compound of formula (I): ##STR1## or a salt, ester or amide thereof, in which Y is a group --O(CH2)m --, --(CH2)m -- or --CHCH-- where m is an integer of from 1 to 5 n is an integer of from 4 t...
47	4670465	Arachidonic acid analogs Long chain unsaturated hydrocarbon derivatives, having from 13 to 21 carbon atoms, which are substituted at the 1-position by a phenoxy, phenylthio or a phenyl that bear a carboxylic acid group at...
48	4613692	Process for the preparation of cinnamic acids which are optionally substituted in the nucleus A process for the preparation of cinnamic acid is provided by the present invention in which an optionally substituted benzaldehyde and alkali metal salt of carboxylic acid and/or alkali metal (bi)...
49	4609756	Process for the preparation of optionally substituted cinnamic acid in the presence of a catalyst In the preparation of a cinnamic acid by reacting the corresponding benzaldehyde with ketene in the presence of a catalyst, the improvement which comprises using as the catalyst an iron and/or zinc...
50	4599469	Hydrogenation process Process for the hydrogenation of functionally substituted acetylenic compounds employing catalyst comprising nickel boride on an inorganic oxide support is disclosed. Functionally-substituted...

Matches 1 - 50 out of 152

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