Patents in Class 562/491

Matches 1 - 50 out of 137

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Match	Document	Document Title
1	7560589	Cycloalkylidene compounds as modulators of estrogen receptor The present invention relates to novel compounds with a variety of therapeutic uses, more particularly novel substituted cyclic alkylidene compounds that are particularly useful for selective...
2	7442833	Triphenylethylene compounds as selective estrogen receptor modulators Compounds of formula (I): with a variety of therapeutic uses, more particularly novel prodrugs that are particularly useful for delivering a parent compound for selective estrogen receptor...
3	7442832	Painless injectable compositions containing salts of 2-arylpropionic acids The invention relates to pharmaceutical compositions of alkylammonium salts of 2-aryipropionic acids, including ketoprofen, ibuprofen, naproxen and tiaprofenic acid. The compositions are suitable...
4	7425650	Synthesis of asymmetric tetracarboxylic acids and corresponding dianhydrides This invention relates to processes for preparing asymmetrical biphenyl tetracarboxylic acids and the corresponding asymmetrical dianhydrides, namely 2,3,3′,4′-biphenyl dianhydride (a-BPDA),...
5	7338977	Anti-viral compounds Compounds of formula I wherein at least one R 1 is H and the remainder are CH 2 CO 2 K; R 2 is and L is H are described. The compounds are useful as pharmaceutical compositions in the...
6	6864390	Method for the stereoselective synthesis of cyclic amino acids The instant invention is a route to stereospecific 3-substituted 5-membered ring isomers of Formula (A). The final products are useful as agents in the treatment of epilepsy, faintness attacks,...
7	6838574	Dicarba-closo-dodecarborane derivatives A medicament comprising as an active ingredient a compound or a physiologically acceptable salt thereof represented by general formula (I): wherein R 1 represents a...
8	6825378	Process for the synthesis of enantiomerically pure cyclohexylphenyl glycolic acid The present invention provides a process for the synthesis of enantiomerically pure cyclohexylphenyl glycolic acid of formula ( 1 ). The present invention more particularly relates to a process...
9	6743784	Estrogen mimetics lacking reproductive tract effects A method for treating symptoms, diseases and conditions in extra-reproductive tract tissues that are responsive to treatment with estrogen, using triarylethanes of formula (I) wherein R 1 is...
10	6566548	Molecular compounds containing novel carboxylic acid derivatives as the constituent compound Novel molecular compounds containing carboxylic acid derivatives represented by general formula (I) or (II) as the constituent compound and exhibiting excellent performances in various technical...
11	6528681	Halogenated triphenylethylene derivatives as selective estrogen receptor modulators The present invention describes novel halogenated triphenylethylene derivatives, or pharmaceutically acceptable prodrug or salt forms thereof, as selective estrogen receptor modulators for the...
12	6417394	Specific salt forms of triphenylethylene derivatives as selective estrogen receptor modulators This invention pertains to novel salt forms of trophenylethylene compound, such as 3-[4(1,2-diphenyl-but-1-enyl)-phenyl]-acrylic acid, as selective estrogen receptor modulators. This invention also...
13	6376684	Stereoselective process for alkyl phenylglycolic acids A process for preparing an alkyl phenylglycolic acid is disclosed. It follows the sequence of condensing a substituted acetaldehyde with mandelic acid to provide a 5-phenyl-1,3-dioxolan-4-one,...
14	6268535	Synthesis of 3-aryl-1-indanamines The present invention is a method of preparing a 3-aryl-1-indanamine represented by structural formula I: ##STR1## and physiologically acceptable salts thereof. In structure I, phenyl ring A can be...
15	6239284	Aromatic tetracyclic compounds of the retinoid type method for preparing and use The invention concerns aromatic tetralcyclic compounds of the retinoid type of general formula (I). The invention also concerns the method for preparing them and the pharmaceutical compositions...
16	6235923	Trisubstituted phenyl derivatives having retinoid agonist, antagonist or inverse agonist type biological activity Compounds of the formula ##STR1## where the symbols have the meaning defined in the specification, have retinoid, retinois antagonist or retinoid inverse agonist type biological activity.
17	6207716	Non-steroidal ligands for the estrogen receptor Novel non-steroidal ligands for the estrogen receptor which possess tissue-dependent estrogenic and antiestrogenic activity as well as methods for making the same and their applications in treating...
18	6127573	Oxidaton of primary alcohols to carboxylic acids with a TEMPO catalyst using NaClO.sub.2 and NaClO The present invention relates to a TEMPO-catalyzed oxidation of primary alcohols, RCH 2 OH to corresponding carboxylic acids, RCOOH in the presence of catalytic in the presence of catalytic amount...
19	5639894	Carbonylation of allylic alcohols and synthesis of an ambergris fragrance compound A process for the carbonylation of allylic alcohols such as nerolidol, farnesol, or their monocyclic analogues with carbon monoxide at a pressure of at least 30 bar in the presence of a polar...
20	5530157	Anti-inflammatory benzoic acid derivatives Novel benzoic acid derivatives have the formula: ##STR1## wherein --X-- represents C 1 to C 6 alkylene, C 2 to C 6 alkenylene or a divalent moiety having the structure --(CH 2 ) m --Z-- in...
21	5288908	Process for the preparation of fluorine containing monomers Compounds of the formula ##STR1## in which X represents hydrogen, --NO 2 or --NH 2 and Y represents --CH 3 , --COOH, --CONH 2 , --NH 2 or --NN--Z, in which the group --Z is ##STR2## with the...
22	5235091	Process for preparing diphenylmethane compounds A diphenylmethane compound (III) can be produced in a good yield by allowing a phenol compound (I) to react with a stilbene compound (II) in the presence of methanesulfonic acid ##STR1##
23	5189181	Process for preparation 2,6-dihydrobenzo[1:26, 4:5-6]-difuran dyes A process for the preparation of a polycyclic dye of the Formula (1): ##STR1## by reacting a substituted acetic acid of the Formula (2): ##STR2## with a compound of the Formula (3): ##STR3## and...
24	5189212	Triarylethylene carboxylic acids with estrogenic activity Nonsteroidal estrogenic triarylethylene carboxylic acids of the formula ##STR1## wherein R is (CH 2 ) m O or (CH 2 ) n , where m is an integer from 1 to 4 and n is an integer from 0 to 4, X is...
25	5136081	Process for the preparation of cyclopentene, cyclopentane and cyclohexane derivatives The invention provides a process for the preparation of fungicidally active cyclopentene derivatives of the general formula ##STR1## cyclopentane derivatives of the general formula ##STR2## and...
26	4999450	Process for preparing alpha-(3-benzylphenyl) propionic acid derivative A process for preparing α-(3-benzylphenyl)-propionic acid or its derivative, a precursor of ketoprofen (trade name), which comprises dehydrogenating a by-product oil fraction formed in the...
27	4937375	(Phenylethenyl)phenylpropionic acid and its ester, and method for producing (benzoylphenyl)propionic acid or its ester New compounds of α-(3-(1-phenylethenyl)phenyl)-propionic acid and its esters and a method for producing α-(3-benzoylphenyl)propionic acid which is prepared by oxidizing the former compound as an...
28	4897397	Aryl-alkynoic, alkenoic or alkanoic compounds and compositions useful as antiallergy and anti-inflammatory agents Certain aryl-alkynoic, alkenoic and alkanoic acids and derivatives and their use in treating inflammation, allergy and hyperproliferative skin disease are disclosed.
29	4889947	Ultraviolet radiation absorbing naphthalenylidene compositions Sunscreen compositions are described which contain certain substituted naphthalenylidenes which act as UV filters when incorporated in a carrier in amounts ranging from 0.1-50% by weight.
30	4883916	Polyprenyl Compounds A polyprenyl compound terminated with a group of ##STR1## is novel and useful as an antihypercholesterolemic agent and an antiarteriosclerotic agent, in which X is a group of the formula ##STR2##...
31	4849530	Process for the preparation of crystalline salts or aryloxy-propanolamines The invention relates to novel crystalline salts of aryloxypropanolamines with diphenylacetic acid, a process for their preparation and the use of these salts for the preparation of chemically pure...
32	4845281	Method of preparing ketoprofen A method of preparing ketoprofen by reacting aniline with a halide of an alpha-halogen propionic acid, benzylation of 3-methyl-2-indolinone, alkaline hydrolysis of 5-benzyl-3-methyl-2-indolinone,...
33	4777288	Process for preparing a 4,4-diphenylbutanoic acid derivative A novel three-step process for preparing 4-(3,4-dichlorophenyl)-4-phenylbutanoic acid is disclosed, which involves (1) reducing 4-(3,4-dichlorophenyl)-4-ketobutanoic acid to...
34	4767784	Novel crystalline salts of aryloxy-propanolamines, a process for their preparation and their use The invention relates to novel crystalline salts of aryloxypropanolamines with diphenylacetic acid, a process for their preparation and the use of these salts for the preparation of chemically pure...
35	4748272	Phenoxyphenylacetates for use as potential modulators of arichidonic acid pathways This invention relates to new lipoxygenase inhibitors possessing anti-inflammatory and anti-allergic properties. The present new compounds are of the formula: ##STR1## and salts thereof; wherein ...
36	4727181	Process for the preparation of α-halocinnamate esters Prepare esters of α-halocinnamic acid and related compounds in high yield under relatively mild conditions.
37	4705891	Substituted α-[2'-tricyclo[3.3.1.1.sup.3,7 ]decylidene]-benzeneacetic acid derivatives Substituted α-[2'-tricyclo[3.3.1.1 3 ,7 ]decylidene]-benzeneacetic acid derivatives of the formula: ##STR1## where the R 1 , R 2 and R 3 substituents are independently selected from hydrogen,...
38	4658033	Synthesis of interphenylene prostaglandin analogs New interphenylene prostaglandin (PGH) analogs are prepared by a method which involves reacting a bicyclic olefin, an acetylene compound and a benzylic halide together, in the presence of a...
39	4649207	Derivatives of diphenylhexafluoropropane Derivatives of diphenylhexafluoropropane having the formula: ##STR1## where R is an unsubstituted or substituted alkylene, an epoxy, a silyl or alkoxysilyl group; and where X and Y are hydrogen or...
40	4632785	Thermally activable trimerization catalyst Disclosed is a method for the trimerization of organic isocyanates comprising thermally activating, in the presence of said isocyanates, a catalyst comprising a carboxylic acid salt selected from...
41	4622421	Phenylalkanoic acid derivatives and their use Compounds of formula (I): ##STR1## (wherein R represents hydrogen or a C 1 -C 3 alkyl group) have analgesic, anti-inflammatory and immuno-regulatory activities. The compounds exist in the form of...
42	4585594	Preparation of 4-substituted but-3-ene-1-carboxylic acids and their esters 4-Substituted but-3-ene-1-carboxylic acids and their esters R 1 R 2 CCH--CH 2 --CO--O--R 3 (I, where R 1 is an organic radical, R 2 is H or R 1 , or R 1 and R 2 together form a...
43	4567257	Amidinium salts Disclosed is a novel class of amidinium salts having the formula ##STR1## wherein R 1 , R 2 , R 3 , and R 4 when taken individually are independently selected from lower-alkyl, aralkyl and...
44	4556676	Antidepressant derivatives of trans-4-phenyl-1,2,3,4-tetrahydro-1-naphthalenamine Novel trans-isomeric derivatives of 4-phenyl-1,2,3,4-tetrahydro-1-naphthalenamine are useful as antidepressant agents. These novel compounds act to block the synaptosomal uptake of norepinephrine...
45	4492800	Process for the preparation of 1,1-dichloro-alkenes A process for the preparation of a 1,1-dichloro-alkene of the formula ##STR1## in which R 1 is hydrogen, or an optionally substituted alkyl, alkenyl, alkinyl, cycloalkyl, aralkyl, aralkenyl or...
46	4424166	Preparation of 1,1-dihalogeno-alkenes In the preparation of a 1,1-dihalogenoalkene of the formula ##STR1## in which R 1 is a hydrogen atom or an optionally substituted alkyl, alkenyl, alkynyl, cycloalkyl, aralkyl, aralkenyl or aryl...
47	4409397	Asymmetric hydrogenation of tetra-substituted olefinic acids and derivatives Tetra-substituted olefinic acids and derivatives of the formula ##STR1## wherein R is --COOM in which M is a cation forming a soluble salt or --COOR 4 or --CON(R 4 ) 2 in which each R 4 is...
48	4407823	Novel phenylacetic acid derivatives Phenylacetic acid derivatives of the formula ##STR1## wherein n is an integer of 2 to 5; ##STR2## R 1 is hydrogen, halogen, trifluoromethyl, nitro or amino; R 2 and R 3 each independently is...
49	4379765	Pyrazolobenzazepines There are presented compounds of the formulas ##STR1## wherein R 1 is hydrogen or lower alkyl; R 2 and R 3 are selected from the group consisting of hydrogen, lower alkyl, C 2 to C 7 ...
50	4350824	Process for the preparation of 1,1-dichloro-alkenes A process for the preparation of a 1,1-dichloroalkene of the formula ##STR1## in which R 1 is hydrogen, or an optionally substituted alkyl, alkenyl, alkinyl, cycloalkyl, aralkyl, aralkenyl or aryl...

Matches 1 - 50 out of 137

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