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7629155 |
Process for producing 1,4-dihydroxy-2-naphthoic acid
A composition containing 1,4-dihydroxy-2-naphthoic acid at a high concentration is obtained by intracellularly and extracellularly producing 1,4-dihydroxy-2-naphthoic acid using a bacterium...
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7498461 |
Method for the preparation of 6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphthoic acid
A novel method for preparing 6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphthoic acid includes a Suzuki reaction between 3-adamantyl-4-methoxyphenylboronic acid of formula (II):
and...
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6849742 |
Binaphthol derivative and process for producing the same
The present invention provides a binaphthol compound represented by formula [1]:
and a salt thereof. The binaphthol compound of the present invention is useful for manufacturing antiseptic...
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6686386 |
Use of a RAR-&ggr -specific agonist ligand for increasing the rate of apoptosis
The present invention relates to pharmaceutical and cosmetic compositions comprising at least one agonist ligand, which is specific for receptors of the RAR-γ type, which are characterized as...
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6562998 |
Granules of 2-hydroxynaphthalene-3-carboxylic acid and method for preparing the same
Granular product of 2-hydroxynaphthalene-3-carboxylic acid with well-suppressed dusting tendency, and process for preparing the same is provided. Granular product of...
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6548703 |
Toning agent
A toning agent for an azo pigment, an azo pigment with a modified tone, and process for preparing the same are provide. 2-hydroxynaphthalene-3,6-dicarboxylic acid or a derivative thereof is admixed...
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6479549 |
Carnosic acid derivatives for promoting synthesis of nerve growth factor
A novel carnosic acid derivative for promoting the synthesis of nerve growth factor (NGF), a composition comprising the carnosic acid derivative as an effective ingredient, as well as, a method of...
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6465515 |
Solid compositions suitable for oral administration containing non-hydroscopic salts of L-carnitine and alkanoyl L-carnitines
Non-hygrocopic salts of L-carnitine and of the lower alkanoyl L-carnitines with pamoic acid are described, which are used to prepare solid compositions suitable for oral administration. Solid...
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6417178 |
Amyloid binding nitrogen-linked compounds for the antemortem diagnosis of alzheimer's disease, in vivo imaging and prevention of amyloid deposits
Amyloid binding compounds which are derivatives of Chrysamine G, pharmaceutical compositions containing, and methods using such compounds to identify Alzheimer's brain in vivo and to diagnose other...
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6403827 |
Crystal of 2-hydroxynaphthalene-3-carboxylic acid and process for the preparation thereof
The present invention provides crystalline 2-hydroxynaphthalene-3-carboxylic acid (BON) characterized in that the average particle size is equal to or more than 157 μm and the proportion of the...
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6316665 |
Process for producing diacids by carboxylation of phenolic compounds
An oxidation free process for converting a hydroxy substituted aromatic to an aromatic diacid which comprises reacting a hydroxy substituted aromatic with excess basic salt in the presence of...
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6284924 |
Compounds
A novel compound represented by the general formula (1) ##STR1## or salts thereof. The compound is useful as a structural component of polymers such as polyesters and polyamides. The compound...
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6242609 |
Method for manufacturing a color coupler used in a silver halide photographic light-sensitive material
A method for manufacturing a color coupler used in a silver halide photographic light-sensitive material using an ammonium trihalide. Said method for manufacturing the color coupler comprising the...
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6194608 |
Process for separating and purifying alkali metal salts of hydroxynaphthalenecarboxylic acids
The present invention provides a process for separating and purifying alkali metal salts of hydroxynaphthalenecarboxylic acids, in which alkali metal salt(s) of hydroxynaphthalenecarboxylic acid(s)...
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6156750 |
Bioactive bicyclic aromatic compounds and pharmaceutical/cosmetic compositions comprised thereof
Novel pharmaceutically/cosmetically-active bicyclic aromatic compounds have the structural formula (I): ##STR1## and are useful for the treatment of a wide variety of disease states, whether human...
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6124498 |
Hydroxynaphthoic acids and derivatives
In one embodiment, the present invention provides a compound comprising: ##STR1## wherein A=H or OH X=OH, a halogen, OR, NHR, NR'R" where R, R', and R"=H, C 1 -8 alkyl, C 2 -8 alkenyl, or C 2 -8...
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6080888 |
Preparation of olefinic compounds and carboxylic derivatives thereof
Arylolefinic compounds are prepared by reacting aryl halide with an olefinic compound in the presence of a polar liquid reaction medium containing (a) secondary or tertiary amine as a hydrogen...
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5936120 |
Deoxygossylic compounds
The invention provides deoxygossylic compounds having useful biological activities, and methods for the synthesis of these and related compounds. The invention further provides valuable...
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5925487 |
Composition, compound and use
A toner resin composition comprising a toner resin and the metal salt or complex of a carbocyclic hydroxy caboxylic acid containing at least one methylene group optionally substituted by hydroxy or...
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5874614 |
Sodium (S)-2-(6-methoxy-2-naphthyl)propionate monohydrate
Novel and very useful forms of sodium (S)-2-(6-methoxy-2-naphthyl)propionate are provided. These forms are sodium (S)-2-(6-methoxy-2-naphthyl)propionate monohydrate having an average particle size...
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5859292 |
Preparation of high purity sodium (S)-2(6-methoxy-2-naphthyl)propionate
Sodium (S)-2-(6-methoxy-2-naphthyl)propionate of at least 99% chiral purity is formed from (S)-2-(6-methoxy-2-naphthyl)propionic acid having a chiral purity of at least about 82%, but below 99%....
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5859293 |
High purity carnosic acid from rosemary and sage extracts by pH-controlled precipitation
A process for the extraction and isolation of concentrated carnosic acid from plant matter of the Labiatae family including contacting the plant matter with a water-miscible solvent to form a plant...
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5827855 |
Hexahydronaphthalene ester derivatives their preparation and their therapeutic uses
Compounds of formula (I): ##STR1## wherein R 1 represents a group of formula (II) or (III): ##STR2## R 2 is alkyl, alkenyl or alkynyl; R 3 and R 4 are each hydrogen, alkyl, alkenyl or alkynyl;...
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5808142 |
Process for the preparation of 2-hydroxynaphthalene-6-carboxylic acid
A process for the preparation of 2-hydroxynaphthalene-6-carboxylic acid using potassium carbonate and CO at temperatures above 260° C. and at a pressure of at least 10 bar comprises using...
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5792876 |
Process for producing acetals
A process is described for producing acetals comprising reacting an aldehyde or a ketone with an alcohol in the presence of a titanium compound having an acetylacetone as a ligand, or in the...
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5770766 |
Method for separating and purifying hydroxynaphtalenecarboxylic acids
The present invention provides a method for effectively separating independent hydroxynaphthalene-carboxylic acids by treating a mixture containing various kinds of hydroxynaphthalene-carboxylic...
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5686586 |
Polycyclic aromatic derivatives, process for preparing the same and pharmaceutical and cosmetic compositions containing the same
A polycyclic aromatic compound having the formula ##STR1## and its salts have useful therapeutic and cosmetic action particularly in psoriasis. In the formula, X represents --CHCH--, O or S, ...
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5550284 |
Production method for alkoxynaphthalenecarboxylic acid
Alkoxynaphthalenecarboxylic acid is produced by a process comprising the addition of 1,3-butadiene to alkoxyalkylbenzene to yield an adduct. The adduct is cyclized in the presence of an acid...
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5547983 |
Aromatic and polycyclic compounds and their use in human or veterinary medicine and in cosmetics
Aromatic bicyclic compounds of formula (I) ##STR1## where R 1 is specifically --H, CH 3 , --CH 2 OH, --OH, --CHO, --CONH 2 , --COOH, --COOalkyl, --SH, S-alkyl, etc. . . . ; R 2 is H; R 3 is H,...
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5543564 |
Process for releasing acidic organic compounds from salts thereof by carbon dioxide
This invention embodies a process for releasing acidic organic compounds in high yield and good purity from aqueous solutions of their salts which comprises converting the salts by carbon dioxide...
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5525728 |
Process for the production of sclareolide
A process for the production of sclareolide comprising the steps of: (1) providing an aqueous composition comprised of: (a) water; (b) sclareol, abienol, or a mixture of sclareol and abienol, (c)...
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5426111 |
[Alkoxy-, alkenyloxy-, alkynyloxy-, and phenylmethyloxyalkoxycycloalkyl or alkoxycycloheteroalkyl]naphtho[2,3-c]furan-1(3H)-one inhibitors of 5-lipoxygenase
Compounds of formula ##STR1## Ar is selected from (a) phenyl, (b) phenyl substituted with one or more groups selected from halogen, cyano, alkyl, haloalkyl, alkoxy, and alkoxycarbonyl, (c) furyl,...
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5403953 |
1-phenylbicyclo[2.2.2]octane compounds
Compound of formula (I): ##STR1## in which: R 1 represents halogen, or hydroxy, alkyl, alkoxy, cyano, amino, mercapto, alkylthio or phenoxy, R 2 and R' 2 represent two hydrogen when the ring...
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5380922 |
Benzenedimethanol suitable for micronisation
1-Hydroxy-2-naphthalene carboxylate (hydroxynaphthoate) salt of 4-hydroxy-a 1 -[[[6-(4-phenylbutoxy)hexyl]-amino]methyl]-1,3-benzendimetha
nol in the form of spherical accretions of microcrystals,...
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RE34805 |
Benzonaphthalene derivatives and their use in therapeutic and cosmetic compositions
A benzonaphthalene compound has the formula ##STR1## wherein R 1 represents ##STR2## or (ii) --CH 2 OH; R 6 represents ##STR3## or OR 7 wherein R 7 represents hydrogen, alkyl having 1-20...
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5344970 |
Hydrogenation of aromatic-substituted olefins using organometallic catalyst
A ruthenium-phosphite complex having the formula ##STR1## wherein a is from 1 to 3; b is 1 or 2; c is from 0 to 3; and R is hydrogen, alkyl, aryl, halo, amino, acetylamino, or sulfo; and X is...
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5340931 |
Aromatic allene compounds of the formula (CH.sub.2 CH--O).sub.n --R--(A.sub.m in which R is an aromatic group and preparation thereof
Allene compounds have the formula: (CH 2 CCH--O) n --R--(A) m (I) in which R is a substituted or unsubstituted mono- or polyvalent benzene, naphthalene, anthracene, azobenzene,...
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5338773 |
Dental composition and method
The invention provides dental cement compositions and methods of using them for binding hard tooth material, metal and ceramic. The cement compositions include polymerizable acid reactive...
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5338881 |
Process for preparing diketones
This invention concerns a process for preparing diketones and keto-acids by reacting a dicarboxylic acid and an aromatic compound in the presence of an alkylsulfonic acid such as methanesulfonic...
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5332857 |
3,5-dihydroxy-6,8-nonadienoic acids and derivatives as hypocholesterolemic agents
Variously substituted 3,5-dihydroxy-6,8-nonadienoic acids and esters, are blood cholesterol lowering agents and so are useful in the prevention and treatment of cardiovascular diseases such as...
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5258532 |
Compound, preparation and use
A fused ring compound having hydroxy, carboxylic acid and hydroxyalkyl substituent groups and the metal salts or complexes thereof. The hydroxyalkyl group is especially a hydroxymethyl group. The...
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5196575 |
Supercritical separation of isomers of functional organic compounds at moderate conditions
A method of separating isomers of functionalized aromatic compounds using solvent-modified supercritical carbon dioxide is disclosed and claimed. In one embodiment, isomers of hydroxynaphthoic acid...
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5169978 |
Naphthyloxybenzoic and naphthloxynaphthoic acid compounds
Novel (naphthyloxy)benzoic/naphthoic acid compounds, polymerizable into thermotropic polymers have the formulae: ##STR1## in which R is hydrogen, a straight or branched chain aliphatic or...
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5155229 |
Derivatives of pravastatin and method of making the same
Derivatives of pravastatin are provided which are useful in inhibiting cholesterol biosynthesis and in preparing radiolabeled compounds useful in the radioimmunoassay (RIA) of pravastatin and...
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5151549 |
Naphthalene compounds
A compound represented by the formula: ##STR1## and a compound represented by the formula: ##STR2## wherein R is C 1 -C 3 alkyl or C 1 -C 3 alkoxy, which is an intermediate for producing the...
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5084575 |
Quinoline substituted naphthalenepropionic acid derivatives as anti-inflammatory/antiallergic agents
There are disclosed compounds of the formula ##STR1## wherein a is alkyl 3-19 carbon atoms, diloweralkyl allyl, diahaloallyl, diphenylallyl, lower alkynyl, ##STR2## W is --CR 2 O--, --CHCH-- or...
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5081263 |
Dioxane adducts of aromatic meta- or para-hydroxy-carboxlic acids
The invention relates to the dioxane adducts of armoatic meta-or para-hydroxycarboxylic acids, which consist, per mole, of 1 mole of 1,4-dioxane and about 2 moles of hydroxycarboxylic acid. The...
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5047558 |
Process for the preparation of a dioxane adduct of 2-hydroxynaphthalene-6-carboxylic acid
The invention relates to the dioxane adduct of 2-hydroxynaphthalene-6-carboxylic acid which adduct comprises 1 mol of 1,4-dioxane and about 2 mol of 2-hydroxynaphthalene-6-carboxylic acid per mol....
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5041639 |
Polysubstituted derivatives of naphtalene, their process of preparation and their application in the cosmetic and pharmaceutical fields
New polysubstituted derivatives of naphthalene. These derivatives correspond to the following formula: ##STR1## in which: R 1 to R 4 is H or CH 3 R 5 is ##STR2## or (iv) the radical:...
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5026726 |
Gossylic iminolactones and gossylic lactones and their anti-viral activities
A compound of the chemical formula ##STR1## wherein n is 1 or 2, X is NH and O, and R 1 and R 2 are H, (C 1 -C 12 ) alkyl, (C 2 -C 12 )alkenyl, (C 2 -C 12 )alkynyl, (C 2 -C 12 )acyl, (C 6 -C...
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