Matches 101 - 150 out of 384 < 1 2 3 4 5 6 7 8 >
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6271416 Quinolinone derivative, method for preparing the same, and anti-allergic agent  
The present invention relates to a simple method for preparing a quinolinone derivative, which is effective as a medicine, e.g., as an agent for treating allergic diseases and the like; novel amide...
6258982 Process for the preparation of substituted aromatic amino compounds  
The present invention relates to a hydrogenation process for the preparation of aromatic amino compounds containing directly on the aryl ring or in a side chain one or more entities that may also...
6252107 Carboxy amphoteric surfactant complexes  
The present invention is directed to a class of compounds that are made by neutralizing the amino group in an amphoteric surfactant with the carboxylic acid group. The complex has (a) lower...
6245937 Liquid phase parallel synthesis of chemical libraries  
This invention features methods of biphasic synthesis for synthesizing combinatorial libraries and combinatorial libraries of chemical compounds utilizing the template, and combinatorial libraries...
6239111 In vivo method of improving survival rate of brain neurons  
The present invention discloses the use, in the manufacture of a preventive and therapeutic drug of a brain disease, of a compound represented by formula (1): CH 2 CH--CH 2 --S(O) n --R (1)...
6171866 Luminescence indicator for determining calcium ions  
The invention relates to a compound having the general Formula I: ##STR1## including its salts, where Z is either the group having the general Formula II: ##STR2## where R 1 is alkyl having 1-4...
6172058 Compounds with pharmaceutical properties  
A pharmaceutical compound of the formula ##STR1## in which R 1 is C 1 -10 alkyl, C 2 -10 alkenyl, C 2 -10 alkynyl, C 3 -10 cycloalkyl, C 3 -10 cycloalkyl-C 1 -10 alkyl, C 3 -10 cycloalkyl-C 2 -10...
6168913 Coding combinatorial libraries with fluorine tags  
The present invention relates to coding combinatorial chemical libraries synthesized on a plurality of solid supports by attaching "tags" that comprise fluorine containing compounds in combinations...
6130315 Peptidase inhibitors  
This invention relates to analogs of peptidase substrates in which the amide group containing the scissile amide bond of the substrate peptide has been replaced by an activated electrophilic ketone...
6063815 Benzopenones useful in the treatment of insulin resistance and hyperglycemia  
This invention provides compounds of Formula I having the structure ##STR1## wherein Y is ##STR2## R 1 and R 2 are each, independently, hydrogen, alkyl of 1-6 carbon atoms, halogen,...
6034067 Serine protease inhibitors  
The invention relates to a compound having formula (I), wherein A, B, X, N, Z and Q are defined as described in the description. The compounds of the invention have anticoagulant activity and can...
6030619 Molecular mimetics of meningococcal B epitopes  
Molecular mimetics of unique epitopes of Neisseria meningitidis serogroup B ("MenB") are disclosed. Compositions containing such molecular mimetics can be used to prevent MenB or E. coli K1 disease...
6015792 Specific eatable taste modifiers  
Ingestible compounds which are substantially tasteless and which have been found to be effective reducers or eliminators of undesirable tastes for eatables.
6011174 Cyclic amic acid derivatives  
The present invention relates to a compound of the formula (I), or its pharmaceutically acceptable salt or ester: ##STR1## wherein Ar 1 is an aryl group or a heteroaromatic ring group; Ar is a...
6001877 Phenylalkan(en)oic acid  
The phenylalkan(en)oic acids of the formula: ##STR1## as defined herein, posses an antagonistic activity on leukotriene B 4 .
5998654 Retinoic acid receptor antagonist compounds and methods  
Trienoic compounds having activity as antagonists for retinoic acid receptors are provided. Also provided are pharmaceutical compositions incorporating such compounds and methods for their...
5998594 Self-assembling, chromogenic receptors for the recognition of medically important substrates and their method of use  
A chromogenic receptor comprises a self-assembled chromogenic compound having at least one intrinsic binding site. The chromogenic compound is characterized by the property of producing a...
5981595 Sulfonyl urea and carbamate ACAT inhibitors  
A pharmaceutically useful compound which lowers blood cholesterol levels having the formula ##STR1## wherein X is oxygen or --NH--; Ar is phenyl, substituted phenyl, naphthyl or substituted...
5981556 1,3-diazolino and 1,3-diazolidino heterocycles as useful nitric oxide synthase inhibitors  
1,3-diazolino and 1,3-diazolidino heterocycle derivatives useful as nitric oxide synthase inhibitors.
5968581 Dipeptide derivatives and sweetening agents  
Novel dipeptide derivatives, such as N-3,3-dimethylbutyl-α-L-aspartyl-α-methyl-L-phenylalanine methyl ester and N-3,3-dimethylbutyl-α-L-aspartyl-α-methyl-L-tyrosine methyl ester, and sweetening...
5958496 Aspartyl dipeptide amide derivatives and sweeteners  
Novel aspartyldipeptidoamides and salts thereof. The apartyldipeptides are useful as a low-calorie sweetener for food and beverage products and have excellent taste and chemical stability.
5945408 Hydroxyanidino derivatives useful as nitric oxide synthase inhibitors  
The current invention discloses hydroxyamidino derivatives useful as nitric oxide synthase inhibitors.
5942544 α-branched anilines, toluenes, and analogs thereof as factor Xa inhibitors  
The present application describes m-amidino phenyl analogs of formula I: ##STR1## wherein D can be amidino and E can be phenyl, which are useful as inhibitors of factor Xa.
5936055 Acid functionalized polyurethane adducts  
Disclosed is an acid-funtionalized polyurethane adduct and a process for the preparation of such adduct. The adduct having a linear or preferably branched structure comprises a plurality of...
5936119 Chemical process  
The invention provides a process for the preparation of 3-(N,N-dimethylamino)benzoic acid which comprises subjecting an aqueous solution of an alkali metal salt or ammonium salt of 3-aminobenzoic...
5922681 Endothelin antagonists  
Antagonists of endothelin are described, as well as methods of using them and pharmaceutical compositions containing them. These compounds are useful in controlling hypertension, myocardial...
5905166 Type of dye in photographic materials  
A new type of yellow dyes with general formula Q-CO--CO--X is disclosed. They can be used in photographic materials as antihalation dyes, acutance dyes or filter dyes. Preferably they are...
5892112 Process for preparing synthetic matrix metalloprotease inhibitors  
Synthetic mammalian matrix metalloprotease inhibitors are disclosed that are useful for treating or preventing diseases wherein said diseases are caused by unwanted mammalian matrix metalloprotease...
5883129 Hydroxylated anthranilic acid derivatives  
The present invention relates to novel derivatives of 3-hydroxyanthranilic acid, 3-HANA, of the general formula I ##STR1## wherein R 1 and R 2 are the same or different and selected from H and...
5872281 Amino acid derivative having N,N-dialkylaminophenyl group  
A compound of the formula ##STR1## wherein R 1 is hydrogen, lower alkyl, phenyl-lower alkyl, lower alkanoyl or benzoyl, and each phenyl in the phenyl-lower alkyl and the benzoyl is unsubstituted...
5871713 Macromolecular polyamine iodine-containing compound, process for its preparation and its use as a contrast agent  
Biological or synthetic macromolecular polyamine compound. optionally of the dendrimer type, characterized in that it carries at least three radio-opaque iodine-containing derivatives.
5804595 Kappa opioid receptor agonists  
The invention provides certain amino acid conjugates of substituted 2-phenyl-N- 1-(phenyl)-2-(1-heterocycloalkyl- or heterocycloaryl-)ethyl!acetamides useful for selectively agonizing kappa opioid...
5801274 N- mercaptoacyl(amino acid or peptide)! compounds and S-lipophilic aliphatic carbonyl derivatives thereof as antihypertensives  
N- Mercaptoacyl(amino acid or peptide)! compounds and S-lipophilic aliphatic carbonyl derivatives thereof, and pharmaceutical compositions comprising such compounds, as well as the use of these...
5795612 Aspartyldipeptideamine derivatives and sweetner  
Novel aspartyldipeptideamide derivatives of formula (I): L--Asp--X--NH--C*HR 1 R 2 and salts thereof, wherein X is a D-α-amino acid residue or a DL-α-amino acid residue selected from the group...
5783593 Inhibitors of squalene synthetase and protein farnesyltransferase  
The present invention provides a compound of the formula ##STR1## which inhibit squalene synthetase and cholesterol biosynthesis and are useful in the treatment of e.g., hyperlipidaemia,...
5780090 Flavored products and a process for their preparation  
Tripeptides containing a hydrophobic amino acid residue and at least one acidic amino acid residue, together with amino acid derivatives having a structure of the N-lactoyl-X type, where X...
5780509 Compound bearing two, 2,6-diiodophenol-4-YL groups and diagnostic drug for iodine allergy  
A compound bearing at least two 2,6-diiodophenyl-4-yl groups represented by formula (IV), particularly a polymer composed of two to eight iodinated tyrosine molecules condensed with each other....
5777176 4,4-(disubstituted)cyclohexan-1-ol dimers and related compounds  
The present invention relates to novel dimers of 4.4-(disubstituted)cyclohexan-1-ol dimers and delated compounds, pharmaceutical compositions containing these compounds, and their use in treating...
5777160 1, 4, 4-(trisubstituted) cyclohex-1-ene dimers and related compounds  
This invention relates to certain 1,4,4-(trsubstituted)cyclohex-1-ene dimers and rlated compounds which are useful in treating allergic and inflammatory diseases and for inhibiting the production...
5756838 Method of asymmetrically synthesizing optically active compounds using supported phase chiral sulfonated BINAP catalyst  
The present invention relates to water soluble chiral sulfonated 2,2'-bis(diphenylphosphino)-1,1'-binaphthyl and its use as organometallic catalysts for asymmetric synthesis of optically active...
5744611 Process for the reduction of amino acids and the derivatives thereof  
A process is disclosed for reducing amino acids and derivatives thereof Compounds of formula (I), in which n=0 or 1 and R 1 , R 2 , R 3 , R 4 , R 5 and R 6 have the meanings given in the...
5731459 Process for separating amino acids and aminosulponic acids through adsorption on zeolites  
The invention relates to a process for removing amino acids and/or aminosulphonic acids from preferably aqueous solutions which contain these as impurities by adsorbing the amino acids on zeolites....
5721234 Glutamate receptor antagonists: fused cycloalkylouinoxalinediones  
Novel glutamate receptor antagonists represented by the formula ##STR1## or a pharmaceutically acceptable salt thereof, wherein Z is an alicyclic fused ring having 5 to 7 carbon atoms; R 1 ...
5719306 LTA.sub.4 hydrolase inhibitors  
The present invention provides compounds of the formula Ar 1 --Q--Ar 2 --Y--R--Z and pharmaceutically acceptable salts thereof wherein Ar 1 and Ar 2 are optionally substituted aryl moieties, Z...
5717109 Excitatory amino acid receptor antagonists  
The present invention provides compounds of formula ##STR1## in which R represents an organic group, or a pharmaceutically acceptable metabolically labile ester or amide thereof, or a...
5714632 Azlactone-based surfactants  
A compound of the formula ##STR1## wherein Q is an organic group of at least two carbon atoms having at least m substituents, m is 1, 2, 3, 4, 5 or 6, and n is 0 or 1. R 3 is H or methyl,...
5693320 (Meth)acryloyloxy substituted acetylsalicylates and polymers thereof  
Novel acetylsalicylic acid derivatives having general formula (I) are provided, in which R 1 is hydrogen or methyl; R 2 is --O-- or --NH--; and W is hydroxy, halogen, lower alkoxy, lower...
5665876 3-(aminoacyl-amino)-saccharides and processes for their preparation  
The invention pertains to 3-(aminoacyl-amino)-saccharides of the general formula (I), ##STR1## wherein R' is selected from the group consisting of hydrogen, a carboxyl group, a phenyl group and an...
5646184 Preparation for external application to the skin and novel benzoic acid derivatives  
Disclosed is a preparation for external application to the skin characterized by containing at least one of benzoic acid derivatives represented by formula (I) or pharmacologically acceptable salts...
5646327 Method for preparing hydroxylamines using vinylic compounds without base neutralization and reaction mixture produced thereby  
Substituted hydroxylamines useful in photographic processing solution can be prepared by reacting a hydroxylamine with a vinylic compound having an electron withdrawing substituent in a suitable...
Matches 101 - 150 out of 384 < 1 2 3 4 5 6 7 8 >