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7612068 |
Aromatic oxyphenyl and aromatic sulfanylphenyl derivatives
The present invention relates to compounds of formula I wherein the substituents are as defined below. The compounds of formula I are useful for the treatment of diseases such as schizophrenia,...
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7576237 |
Process for the synthesis of 2,5-Dihydroxyterephthalic acid
2,5-dihydroxyterephthalic acid is produced in high yields and high purity from 2,5-dihaloterephthalic acid by contact with a copper source and a ligand that coordinates to copper under basic...
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7553990 |
Process for the synthesis of 2, 5-dihydroxyterephthalic acid
2,5-dihydroxyterephthalic acid is produced in high yields and high purity from 2,5-dihaloterephthalic acid by contact with a copper source and a ligand that coordinates to copper under basic...
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7553794 |
Heteropolyacid and or its salt supported catalyst, production process of the catalyst and production process of compound using the catalyst
A supported catalyst comprising a support having supported thereon at least one member selected from the group consisting of heteropolyacids and heteropolyacid salts, in which the heteropolyacid...
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7534912 |
Process for producing pyromellitic acid
A process for producing pyromellitic acid which comprises step A for oxidizing durene, thereby obtaining a reaction mixture comprising trimethyl benzoic acid, trimethyl benzyl alcohol and trimethyl...
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7528173 |
Plasma carboxypeptidase B inhibitors
Compounds of the following formula (I), for example: (1), wherein R 1 , R 2 , R 3 , and R 4 are described herein, are useful as inhibitors of plasma carboxypeptidase B. Pharmaceutical compositions...
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7511170 |
Process for liquid/solid reaction
A process for carrying out a liquid/solid reaction comprises
a) preparing a reaction suspension in which a first reactant is present in suspended form and a second reactant is present in...
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7507817 |
Prostaglandin prodrugs
Novel compounds, and therapeutic methods, compositions and medicament related thereto are disclosed herein.
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7501478 |
Thermoprecipitating polymer containing enzyme specific ligands, process for the preparation thereof, and use thereof for the separation of enzymes
The present invention provides novel thermoprecipitating polymers of formula 1 containing novel enzyme sensitive ligands of the formula 4, processes for the preparation thereof respectively, and to...
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7498436 |
Substituted hydroxyethylamines
This present invention relates to prodrug compounds of the formula (Y) and pharmaceutical salts thereof:
where R N , R 1 , R 2 , R 3 R 4 and R C are defined herein, which are useful in...
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7468167 |
Method for starting up reactor and reactor system
A method for quickly starting up a reactor and a reactor system therefor are provided. A shell-and-tube reactor in the system is adapted to circulate a heat medium having a solid point in the range...
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7439372 |
Therapeutic compounds
A compound having a structure
is disclosed herein. Compositions, medicaments, and therapeutic methods related thereto are also disclosed.
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7432390 |
Production of carboxylic acids or carboxylic acid esters
In the production of carboxylic acid or carboxylic acid ester, a reaction product containing the carboxylic acid or carboxylic acid ester which has been produced by the reaction of an olefin,...
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7411031 |
Synthesis of polyanhydrides
The present invention provides a method for forming compounds of Formula
HO—C(═O)R 1 —X—R 2 —X—R 1...
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7396955 |
Annealed and promoted catalyst
A mixed metal oxide, which may be an orthorhombic phase material, is improved as a catalyst for the production of unsaturated carboxylic acids, or unsaturated nitrites, from alkanes, or mixtures of...
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7388023 |
Amino acids with affinity for the α2δ-protein
Certain β-amino acids that bind to the alpha-2-delta (α2δ) subunit of a calcium channel are disclosed. These compounds and their pharmaceutically acceptable salts are useful in the treatment of...
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7351855 |
Chemically defined non-polymeric valency platform molecules and conjugates thereof
Chemically-defined, non-polymeric valency platform molecules and conjugates comprising chemically-defined valency platform molecules and biological or chemical molecules including polynucleotide...
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7348457 |
Ketol fatty acid derivatives and plant growth regulators
α-Ketol unsaturated fatty acid derivatives represented by the following formula (1), α-ketol unsaturated fatty acid amide derivatives represented by the following formula (6), and plant growth...
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7339076 |
Process for the synthesis of 2,5-dihydroxyterephthalic acid
2,5-dihydroxyterephthalic acid is produced in high yields and high purity from 2,5-dihaloterephthalic acid by contact with a copper source and a ligand that coordinates to copper under basic...
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7326807 |
Polycarboxylic acid production system with enhanced heating for oxidative digestion
Disclosed is an optimized system for more efficiently and economically producing terephthalic acid. The system includes an novel method for heating the slurry and/or reaction medium subjected to...
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7323590 |
Process for rectificatively separating a liquid comprising acrylic acid and/or methacrylic acid
A process for rectificatively separating a liquid which comprises acrylic acid, methacrylic acid or a mixture thereof, and additionally comprises low molecular weight aldehydes and acetone.
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7309718 |
Dibenzocycloheptene compound
The present invention discloses a dibenzocycloheptene compound represented by the formula (I):
wherein R 1 : hydrogen atom, halogen atom, etc., R 2 : hydrogen atom, halogen atom, etc., A:...
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7294739 |
Basic amine esters or oleic acid and their use as anti-inflammatory or immunobodulatory agents
This invention is directed to compounds of the following formula (I):
wherein R is either:
wherein R 1 and R 2 are as defined in the specification; the use of these...
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7285680 |
β-alanine derivatives and the use thereof
A compound of the general formula (I)
(wherein the symbols are as defined in the description), or a prodrug or a salt thereof.
This compound engages in LPA receptor bonding and antagonism and...
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7285572 |
CaSR antagonist
The present invention provides a compound having a calcium-sensitive receptor antagonistic action, a pharmaceutical composition containing the compound, particularly a calcium receptor antagonist...
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7279594 |
Thermoplastic composition, articles thereof, and method of making the articles
A thermoplastic composition comprises greater than or equal to about 60 wt. % polycarbonate; and about 10 wt. % to about 40 wt. % of a polyimide; wherein weight percents are based on a total weight...
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7247745 |
Process for preparing 1,5-diaryl-3-substituted pyrazoles
A process for making a compound of formula I wherein the substituents are as described in the specification comprising reacting a ketone of formula II with succinic anhydride and an alkoxide base...
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7235357 |
Method of reducing background in fluoresence detection
The present invention provides a method for detecting fluorescence by using a solid support to which a probe molecule to be detected is fixed, wherein background is reduced by using a quenching...
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7148377 |
4-Alkoxy cyclohexane-1-amino-carboxylic acid esters and method for the production thereof
The invention relates to novel 4-alkoxy-cyclohexane-1-amino-carboxylic esters of the formula (IV)
in which R 1 represents OR 3 , R 2 represents alkyl, and R 3 represents alkyl, to...
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7138542 |
Method of treating tinnitus
The invention relates to a method of treating tinnitus by administering an alpha2delta ligand such as, for example, a compound of Formula
and pharmaceutically acceptable salts thereof, wherein...
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7119225 |
Gold catalyst for selective oxidation
A supported gold catalyst is used for selective oxidation. In particular, an alcohol or ketone is oxidized to produce the corresponding carboxylic acid, an alcohol is oxidized to produce the...
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7109370 |
Substituted phenylketoenols
The invention relates to novel phenyl-substituted cyclic ketoenols of the formula (I)
in which
A, B, G, X, Y, Z and W are each as defined in the description, to processes and intermediates for...
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7078564 |
Process for the preparation of ωbenzyl esters of amino diacids and of alkanesulphonates of these esters, and these alkanesulphonates
The invention relates to a process for the preparation of an ω-benzyl ester of an amino diacid, characterized in that the amino diacid is reacted with a benzyl alcohol derivative of formula (I)
...
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7071350 |
Method of introducing amino group and method of synthesizing amino acid compound
The present invention relates to a method for introducing an amino group into an organic acid or an organic ester by reacting an organic salt or an organic ester and ammonia under high-temperature...
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7060250 |
Diagnostic imaging contrast agents with extended blood retention
The present invention relates to contrast agents for diagnostic imaging with prolonged blood retention. In particular, this invention relates to novel compounds that are characterized by an image...
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7026505 |
Method of treating tinnitus
The invention relates to a method of treating tinnitus by administering an alpha2delta ligand such as, for example, a compound of Formula
and pharmaceutically acceptable salts thereof, wherein...
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7022875 |
Thiobutacin and antifungal and antioomycete composition for controlling plant diseases using the same
A novel antibiotic thiobutacin, obtainable from Lechevalieria aerocolonigenes strain VK-A9, and antifungal and antioomycete compositions comprising thiobutacin as an active ingredient for control...
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7019165 |
Polyoxometallate catalysts and catalytic processes
An active and selective hydrocarbon partial oxidation catalyst comprises an activated partially-reduced polyoxometallate, preferably niobium polyoxomolybdate, that is prepared from a suitable...
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7005539 |
Ferulic acid dimers and their pharmaceutically acceptable salts, their preparation and use thereof for treating dementia
The present invention relates to ferulic acid dimers and their pharmaceutically acceptable salts, preparation method and use thereof for treating dementia, which have excellent effect on the...
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7002053 |
Method for preparing high-purity diisobutene
The invention relates to a process for preparing high-purity diisobutene by reaction of isobutene or isobutene-containing hydrocarbon mixtures over a solid acidic ion-exchange resin containing...
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6943272 |
Norbornane and norbornene derivatives, use thereof and perfumed products containing same
The invention concerns a novel compounds of formula (I), wherein the dotted line bond is present or not, and wherein R 1 represents: when the dotted line bond is present —CHCH 3 OH or —CHCH 3...
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6927306 |
Process for producing hydrogenated aromatic polycarboxylic acid and process for producing hydrogenated aromatic polycarboxylic anhydride
Disclosed are processes for industrially advantageously producing at a good yield respectively, a hydrogenated aromatic polycarboxylic acid and an acid anhydride thereof each having a high purity....
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6919380 |
Derivatives of C2-substituted indan-1-ol systems for the prophylaxis or treatment of obesity
Derivatives of C2-substituted indan-1-ol compounds of formula I:
its physiologically acceptable salts, and its physiologically functional derivatives for the prophylaxis or treatment of...
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6911556 |
Processes for the preparation of olefins, unsaturated carboxylic acids and unsaturated nitriles from alkanes
Improved processes for the preparation of olefins, unsaturated carboxylic acids and unsaturated nitriles involve the use of dehydrogenation catalysts suitable for the conversion of alkanes to...
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6909015 |
Aromatic polyetherketones
The invention relates to polyetherketones and to a process for the preparation of aromatic polyetherketones which process comprises: a) self-condensing a compound of formula (I) wherein n...
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6897237 |
MMP-12 inhibitors
A compound of the formula (I):
wherein R 1 is hydroxy and the like; R 2 is optionally substituted lower alkyl and the like; R 3 is hydrogen atom and the like; R 4 is optionally substituted...
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6894185 |
Substituted chiral allosteric hemoglobin modifiers
A family of substituted chiral allosteric effectors of hemoglobin is useful for delivering more oxygen to hypoxic and ischemic tissues by reducing the oxygen affinity of hemoglobin in whole blood.
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6884907 |
Hydroxamic acids and acyl hydroxamines as naaladase inhibitors
This invention relates to new compounds, pharmaceutical compositions and diagnostic kits comprising such compounds, and methods of using such compounds for inhibiting NAALADase enzyme activity,...
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6875890 |
Method of producing N, N-dimethyl glycine hydrochloride
A process for preparing N,N-Dimethyl Glycine Hydrochloride, comprises treating a chloroacetic acid with aqueous dimethylamine, and then dropping by hydrochloric acid to obtain N,N-dimethyl glycine...
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6875888 |
Method for the production of esters of unsaturated carboxylic acids
In a process for preparing an ester of an unsaturated carboxylic acid by reacting an ester of the unsaturated carboxylic acid and a C 1 -C 4 -alkanol with an alcohol R 3 OH, where R 3 is a C 4 -C...
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